RTECS NUMBER : LM5075000
CHEMICAL NAME : Fluorescein
CAS REGISTRY NUMBER : 2321-07-5
BEILSTEIN REFERENCE NO. : 0094324
REFERENCE : 5-19-06-00456 (Beilstein Handbook Reference)
LAST UPDATED : 199707
DATA ITEMS CITED : 10
MOLECULAR FORMULA : C20-H12-O5
MOLECULAR WEIGHT : 332.32
WISWESSER LINE NOTATION : T C666 BO EVJ IR BVQ& MQ
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* Benzoic acid, o-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-
* 9-(o-Carboxyphenyl)-6-hydroxy-3-isoxanthenone
* 9-(o-Carboxyphenyl)-6-hydroxy-3H-xanthen-3-one
* C.I. 45350:1
* C.I. 45350A
* C.I. 45350 (free acid)
* C.I. Solvent Yellow 94
* D+C Yellow No. 7
* 3',6'-Dihydroxyfluoran
* Dihydroxyfluorane
* 3',6'-Dihydroxyspiro(isobenzofuran-1(3H),9'(9H)-xanthen)-3-one
* Fluoran, 3',6'-dihydroxy-
* 3,6-Fluorandiol
* 3',6'-Fluorandiol
* Fluoresceine
* Hidacid fluorescein
* Resorcinolphthalein
* Soap Yellow F
* 3H-Xanthen-3-one, 9-(o-carboxyphenyl)-6-hydroxy-
* 11712 Yellow
* Zlut kysela 73
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJLEAG International Journal of Leprosy and Other Mycobacterial Diseases.
(POB 1097, Bloomfield, NJ 07003) V.1- 1933- Volume(issue)/page/year:
2,257,1934
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #4775625
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJLEAG International Journal of Leprosy and Other Mycobacterial Diseases.
(POB 1097, Bloomfield, NJ 07003) V.1- 1933- Volume(issue)/page/year:
2,257,1934
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
** MUTATION DATA **
TYPE OF TEST : DNA adduct
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 15 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 33350
No. of Facilities: 495 (estimated)
No. of Industries: 18
No. of Occupations: 21
No. of Employees: 5188 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 33350
No. of Facilities: 2171 (estimated)
No. of Industries: 42
No. of Occupations: 55
No. of Employees: 88495 (estimated)
No. of Female Employees: 21558 (estimated)
*** STATUS IN U.S. ***
EPA GENETOX PROGRAM 1988, Inconclusive: B subtilis rec assay
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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