EMS CATALOG NO: 13390
EMS PRODUCT: Dimethyl Sulfoxide
DATE: 10/24/2007
PAGE NUMBER: One of 6
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered accurate. However,
no warranty is expressed or implied regarding the accuracy of these data or the
results to be obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for personal injury or
property damage to vendees, users or third parties caused by the material. Such
vendees or users assume all risks associated with the use of the material.
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PRODUCT IDENTIFICATION
COMMON NAME: Dimethyl Sulfoxide
COMMERCIAL NAME(S): Not available.
SYNONYM: DMSO; SULFINYLBIS {METHANE}
CHEMICAL NAME: N/A
CHEMICAL FAMILY: Solvent
CHEMICAL FORMULA: (CH3)2SO
CAS#: 67-68-5
RTECS: PV6210000
TSCA: TSCA 8(b) inventory: Dimethyl Sulfoxide
CI#: Not applicable.
COMPOSITION AND INFORMATION ON INGREDIENTS
NAME: Dimethyl Sulfoxide
CAS#: 67-68-5
TWA(mg/m3):
STEL (mg/m3):
% BY WEIGHT: 100
TOXICOLOGICAL DATA ON INGREDIENTS:
ORAL (LD50): Acute: 14500 mg/kg [Rat]. 7920 mg/kg [Mouse].
HAZARDS IDENTIFICATION
POTENTIAL ACUTE HEALTH EFFECTS: Extremely hazardous in case of skin contact
(permeator), of ingestion. Very hazardous in case of eye contact (irritant), of inhalation.
Hazardous in case of skin contact (irritant). Inflammation of the eye is characterized by
redness, watering, and itching.
POTENTIAL CHRONIC HEALTH EFFECTS:
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
The substance is toxic to blood, kidneys, lungs, the nervous system, liver, mucous
membranes. Repeated or prolonged exposure to the substance can produce target
organs damage.
FIRST AID MEASURES
EYE CONTACT: Check for and remove any contact lenses. Immediately flush eyes with
running water for at least 15 minutes, keeping eyelids open. Cold water may be used.
Do not use an eye ointment. Seek medical attention.
SKIN CONTACT: After contact with skin, wash immediately with plenty of water.
Gently and thoroughly wash the contaminated skin with running water and non-abrasive
soap. Be particularly careful to clean folds, crevices, creases and groin. Cold water may
be used. Cover the irritated skin with an emollient. If irritation persists, seek medical
attention. Wash contaminated clothing before reusing.
SERIOUS SKIN CONTACT: Wash with a disinfectant soap and cover the contaminated
skin with an anti-bacterial cream. Seek medical attention.
INHALATION: Remove to fresh air. Loosen tight clothing such as a collar, tie belt or
waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek
immediate medical attention.
SERIOUS INHALATION: Not available.
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Dimethyl Sulfoxide
INGESTION : Induce vomiting. Loosen tight clothing such as a collar, tie, belt or
waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek
immediate medical attention.
SERIOUS INGESTION: Not available.
FIRE AND EXPLOSION DATA
FLAMMABILITY OF THE PRODUCT: Combustible.
AUTO-IGNITION TEMPERATURE: 215oC (419oF)
FLASH POINTS: Closed Cup: 89oC (192.2oF)
Open Cup: 95oC (203oF)
FLAMMABLE LIMITS: Lower: 2.6%
Upper: 42%
PRODUCTS OF COMBUSTION: These products are carbon oxides (CO, CO2), sulfur
oxides (SO2, SO3鈥?)
FIRE HAZARDS IN PRESENCE OF VARIOUS SUBSTANCES: Not available.
EXPLOSION HAZARDS IN PRESENCE OF VARIOUS SUBSTANCES:
RISKS OF EXPLOSION OF THE PRODUCT IN PRESENCE OF MECHANICAL
IMPACT: Not available.
RISKS OF EXPLOSION OF THE PRODUCT IN PRESENCE OF STATIC
DISCHARGE: Not available.
FIRE FIGHTING MEDIA AND INSTRUCTIONS:
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
SPECIAL REMARKS ON FIRE HAZARDS: Not available.
SPECIAL REMARKS ON EXPLOSION HAZARDS: Not available.
ACCIDENTAL RELEASE MEASURES
SMALL SPILL: Dilute with water and mop up, or absorb with an inert dry material and
place in an appropriate waste disposal container. Finish cleaning by spreading water on
the contaminated surface and dispose of according to local and regional authority
requirements.
LARGE SPILL: Combustible material. Keep away from heat. Keep away from sources
of ignition. Stop leak if without risk. If the product is in its solid form: Use a shovel to
put the material into a convenient waste disposal container. If the product is in its liquid
form: Absorb with an inert material and put the spilled material in an appropriate waste
disposal. Finish cleaning by spreading water on the contaminated surface and allow to
evacuate through the sanitary system.
HANDLING AND STORAGE
PRECAUTIONS: Keep away from heat. Keep away from sources of ignition. Ground all
equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapor/ spray.
In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek
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Dimethyl Sulfoxide
medical advice immediately and show the container or the label. Avoid contact with skin
and eyes.
STORAGE: Flammable materials should be stored in a separate safety storage cabinet
or room. Keep away from heat. Keep away from sources of ignition. Keep container
tightly closed. Keep in a cool, well-ventilated place. Ground all equipment containing
material. Keep container dry. Keep in a cool place.
EXPOSURE CONTROLS/PERSONAL PROTECTION
ENGINEERING CONTROLS: Provide exhaust ventilation or other engineering
controlled to keep the airborne concentrations of vapors below their respective threshold
limit value. Ensure that eyewash stations and safety showers are proximal to the work-
station location.
PERSONAL PROTECTION: Splash goggles. Lab coat. Vapor respirator. Be sure to
use an approved/certified respirator or equivalent. Gloves.
PERSONAL PROTECTION IN CASE OF A LARGE SPILL: Splash goggles. Full suit.
Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used
to avoid inhalation of the product. Suggested protective clothing might not be sufficient;
consult a specialist BEFORE handling this product.
EXPOSURE LIMITS: Not available.
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE AND APPEARANCE: Liquid.
ODOR: Garlic like
TASTE: Not available.
COLOR: Clear Colorless.
MOLECULAR WEIGHT: 78.13 g/mole
pH (1% SOLN/WATER): Not available.
BOILING POINT: 189oC (372.2oF)
MELTING POINT: 18.45oC (62.2oF)
CRITICAL TEMPERATURE: Not available.
SPECIFIC GRAVITY: 1.1008 (Water=1)
VAPOR PRESSURE: 0.417 mm of Hg (@20oC)
VAPOR DENSITY: 2.7 (Air=1)
VOLATILITY: Not available.
ODOR THRESHOLD: Not available.
WATER/OIL DIST. COEFF.: The product is more soluble in oil; log (oil/water)=107
IONICITY (IN WATER): Not available.
DISPERSION PROPERTIES: See solubility in water.
SOLUBILITY: Easily soluble in cold water, hot water.
STABILITY AND REACTIVITY DATA
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Dimethyl Sulfoxide
STABILITY: The product is stable.
INSTABILITY TEMPERATURE: Not available.
CONDITIONS OF INSTABILITY: Not available.
INCOMPATIBILITY WITH VARIOUS SUBSTANCES: Not available.
CORROSIVITY: Non-corrosive in presence of glass.
SPECIAL REMARKS ON REACTIVITY: Not available.
SPECIAL REMARKS ON CORROSIVITY: Not available.
POLYMERIZATION: No.
TOXICOLOGICAL INFORMATION
ROUTES OF ENTRY: Dermal contact. Eye contact. Inhalation. Ingestion.
TOXICITY TO ANIMALS:
Acute oral toxicity (LD50): 7920 mg/kg [Mouse].
CHRONIC EFFECTS ON HUMANS: The substance is toxic to blood, kidneys, lungs, the
nervous system, liver, mucous membranes.
OTHER TOXIC EFFECTS ON HUMANS: Extremely hazardous in case of skin contact
(permeator), of ingestion. Very hazardous in case of inhalation. Hazardous in case of
skin contact (irritant).
SPECIAL REMARKS ON TOXICITY TO ANIMALS: Not available.
SPECIAL REMARKS ON CHRONIC EFFECTS ON HUMANS: Not available.
SPECIAL REMARKS ON OTHER TOXIC EFFECTS ON HUMANS: Not available.
ECOLOGICAL INFORMATION
ECOTOXICITY: Not available.
BOD5 AND COD: Not available.
PRODUCTS OF BIODEGRADATION: Possibly hazardous short term degradation
products are not likely. However, long term degradation products may arise.
TOXICITY OF THE PRODUCTS OF BIODEGRADATION: The products of
degradation are more toxic.
SPECIAL REMARKS ON THE PRODUCTS OF BIODEGRADATION: Not available.
DISPOSAL CONSIDERATIONS
WASTE DISPOSAL: Recycle to process, if possible. Consult your local or regional
authorities.
TRANSPORT INFORMATION
DOT CLASSIFICATION: Not a DOT controlled material (United States).
IDENTIFICATION: Not applicable.
SPECIAL PROVISIONS FOR TRANSPORT: Not applicable.
OTHER REGULATORY INFORMATION
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Dimethyl Sulfoxide
FEDERAL AND STATE REGULATIONS:
TSCA 8 (b) INVENTORY: Dimethyl sulfoxide
OTHER REGULATIONS:
OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200)
OTHER CLASSIFICATIONS:
WHMIS (CANADA):
Class B-3: Combustible liquid with a flash point between 37.8oC (100oF)
and 93.3oC (200oF).
Class D-2A-Material causing other toxic effects (VERY TOXIC).
DSCLA (EEC):
R38-Irritating to the skin
R41-Risk of serious damage to eyes.
HMIS (U.S.A.):
HEALTH HAZARD: 1
FIRE HAZARD: 2
REACTIVITY: 0
PERSONAL PROTECTION: h
NATIONAL FIRE PROTECTION ASSOCIATION (U.S.A.)
HEALTH: 1
FLAMMABILITY: 1
REACTIVITY: 0
SPECIFIC HAZARD:
PROTECTIVE EQUIPMENT:
Gloves.
Lab Coat.
Vapor respirator. Be sure to use an approved/certified respirator
or equivalent. Wear appropriate respirator when ventilation is
inadequate.
Splash goggles.
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Dimethyl Sulfoxide
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