Product Name: Ospray Clethodim 240 EC Selective Herbicide
Page: 1 of 6
This revision issued: September, 2006
Section 1 - Identification of Chemical Product and Company
Ospray Pty Ltd Phone: 07 4685 2441 (BH)
50 Middleton Rd Freecall 1800 624 597
Cottonvale Qld 4375 www.ospray.com.au
Substance: Clethodim is a cyclohexanedione oxime derivative.
Ospray Clethodim 240 EC Selective Herbicide
Trade Name:
Product Use: Agricultural herbicide for use as described on the product label.
Creation Date: September, 2006
Revision Date: September, 2006
Section 2 - Hazards Identification
Statement of Hazardous Nature
This product is classified as: Xn, Harmful. Xi, Irritating. Hazardous according to the criteria of ASCC.
Not a Dangerous Good according to the Australian Dangerous Goods (ADG) Code. However, this is a C1
Combustible Liquid and for storage meets the definition of Dangerous Goods.
Risk Phrases: R65, R20/22, R36/38. Harmful: May cause lung damage if swallowed. Harmful by inhalation and if
swallowed. Irritating to eyes and skin.
Safety Phrases: S20, S38, S46, S24/25, S36/37. When using, do not eat or drink. In case of insufficient ventilation,
wear suitable respiratory equipment. If swallowed, contact a doctor or Poisons Information Centre immediately and
show this container or label. Avoid contact with skin and eyes. Wear suitable protective clothing and gloves.
SUSDP Classification: S5
ADG Classification: None allocated. Not a Dangerous Good under the ADG Code.
UN Number: None allocated
Emergency Overview
Physical Description & Colour: Brown-amber coloured liquid.
Odour: Characteristic aromatic hydrocarbon odour.
Major Health Hazards: Effects of acute exposure to Clethodim or formulated products may include eye or skin
irritation or central nervous system effects, e.g., salivation, decreased motor activity, incoordination, unsteady gait and
hyperactivity. This product is harmful by inhalation and if swallowed, irritating to eyes and skin, if aspirated, may
cause lung damage.
Potential Health Effects
See section 11 for Chronic exposure studies.
Inhalation:
Short Term Exposure: Available data shows that this product is harmful, but symptoms are not available. In
addition product may be mildly irritating, although unlikely to cause anything more than mild transient discomfort.
Skin Contact:
Short Term Exposure: Available data indicates that this product is not harmful. It should present no hazards in
normal use. However product is a skin irritant. Symptoms may include itchiness and reddening of contacted skin.
Other symptoms may also become evident, but all should disappear once exposure has ceased.
Eye Contact:
Short Term Exposure: This product is an eye irritant. Symptoms may include stinging and reddening of eyes and
watering which may become copious. Other symptoms may also become evident. If exposure is brief, symptoms
should disappear once exposure has ceased. However, lengthy exposure or delayed treatment may cause permanent
damage.
MATERIAL SAFETY DATA SHEET
Issued by: Ospray Pty Ltd Freecall 1800 624 597 (Business hours)
Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)
Product Name: Ospray Clethodim 240 EC Selective Herbicide
Page: 2 of 6
This revision issued: September, 2006
Ingestion:
Short Term Exposure: Significant oral exposure is considered to be unlikely. Because of the low viscosity of this
product, it may directly enter the lungs if swallowed, or if subsequently vomited. Once in the lungs, it is very difficult to
remove and can cause severe injury or death. However, this product is an oral irritant. Symptoms may include burning
sensation and reddening of skin in mouth and throat. Other symptoms may also become evident, but all should
disappear once exposure has ceased.
Carcinogen Status:
ASCC: No significant ingredient is classified as carcinogenic by ASCC.
NTP: No significant ingredient is classified as carcinogenic by NTP.
IARC: No significant ingredient is classified as carcinogenic by IARC.
Section 3 - Composition/Information on Ingredients
TWA (mg/m3) STEL (mg/m3)
Ingredients CAS No Conc,%
Clethodim 99129-21-2 240g/L not set not set
Non hazardous emulsifier secret 3 approx not set not set
Aromatic hydrocarbons 64742-94-5 to 100 not set not set
This is a commercial product whose exact ratio of components may vary slightly. Minor quantities of other non
hazardous ingredients are also possible.
The ASCC TWA exposure value is the average airborne concentration of a particular substance when calculated over a normal 8 hour working day
for a 5 day working week. The STEL (Short Term Exposure Limit) is an exposure value that may be equalled (but should not be exceeded) for no
longer than 15 minutes and should not be repeated more than 4 times per day. There should be at least 60 minutes between successive exposures
at the STEL. The term "peak "is used when the TWA limit, because of the rapid action of the substance, should never be exceeded, even briefly.
Section 4 - First Aid Measures
General Information:
You should call The Poisons Information Centre if you feel that you may have been poisoned, burned or irritated by
this product. The number is 13 1126 from anywhere in Australia (0800 764 766 in New Zealand) and is available at all
times. Have this MSDS with you when you call.
Inhalation: If symptoms of poisoning become evident, contact a Poisons Information Centre, or call a doctor at
once. Remove source of contamination or move victim to fresh air. If breathing is difficult, oxygen may be beneficial if
administered by trained personnel, preferably on a doctor's advice. DO NOT allow victim to move about
unnecessarily. Symptoms of pulmonary oedema can be delayed up to 48 hours after exposure.
Skin Contact: Wash gently and thoroughly with warm water (use non-abrasive soap if necessary) for 10-20 minutes
or until product is removed. Under running water, remove contaminated clothing, shoes and leather goods (e.g.
watchbands and belts) and completely decontaminate them before reuse or discard. If irritation persists, repeat
flushing and seek medical attention.
Eye Contact: Immediately flush the contaminated eye(s) with lukewarm, gently flowing water for 20 minutes or until
the product is removed, while holding the eyelid(s) open. Take care not to rinse contaminated water into the
unaffected eye or onto the face. Obtain medical attention immediately. Take special care if exposed person is wearing
contact lenses.
Ingestion: If swallowed, do NOT induce vomiting. Wash mouth with water and contact a Poisons Information
Centre, or call a doctor.
Section 5 - Fire Fighting Measures
Fire and Explosion Hazards: This product is classified as a C1 combustible product. There is a slight risk of an
explosion from this product if commercial quantities are involved in a fire. Violent steam generation or eruption may
occur upon application of direct water stream on hot liquids. Vapours from this product are heavier than air and may
accumulate in sumps, pits and other low-lying spaces, forming potentially explosive mixtures. They may also flash
back considerable distances.
Fire decomposition products from this product may be toxic if inhaled. Take appropriate protective measures.
Extinguishing Media: Preferred extinguishing media are carbon dioxide, dry chemical, foam, water fog.
Fire Fighting: If a significant quantity of this product is involved in a fire, call the fire brigade.
Flash point: Approx 65掳C, Closed cup
Upper Flammability Limit: No data.
Lower Flammability Limit: No data.
Autoignition temperature: No data.
Flammability Class: C1
MATERIAL SAFETY DATA SHEET
Issued by: Ospray Pty Ltd Freecall 1800 624 597 (Business hours)
Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)
Product Name: Ospray Clethodim 240 EC Selective Herbicide
Page: 3 of 6
This revision issued: September, 2006
Section 6 - Accidental Release Measures
Accidental release: In the event of a major spill, prevent spillage from entering drains or water courses. Wear full
protective clothing including eye/face protection. All skin areas should be covered. See below under Personal
Protection regarding Australian Standards relating to personal protective equipment. Suitable materials for protective
clothing include rubber, PVC. Eye/face protective equipment should comprise as a minimum, protective glasses and,
preferably, goggles. If there is a significant chance that vapours or mists are likely to build up in the cleanup area, we
recommend that you use a respirator. It should be fitted with a type G cartridge, suitable for agricultural chemicals.
Otherwise, not normally necessary.
Stop leak if safe to do so, and contain spill. Absorb onto sand, vermiculite or other suitable absorbent material. If spill
is too large or if absorbent material is not available, try to create a dike to stop material spreading or going into drains
or waterways. Sweep up and shovel or collect recoverable product into labelled containers for recycling or salvage,
and dispose of promptly. Recycle containers wherever possible after careful cleaning. Refer to product label for
specific instructions. After spills, wash area preventing runoff from entering drains. If a significant quantity of material
enters drains, advise emergency services. Full details regarding disposal of used containers, spillage and unused
material may be found on the label. If there is any conflict between this MSDS and the label, instructions on the label
prevail. Ensure legality of disposal by consulting regulations prior to disposal. Thoroughly launder protective clothing
before storage or re-use. Advise laundry of nature of contamination when sending contaminated clothing to laundry.
Section 7 - Handling and Storage
Handling: Keep exposure to this product to a minimum, and minimise the quantities kept in work areas. Check
Section 8 of this MSDS for details of personal protective measures, and make sure that those measures are followed.
The measures detailed below under "Storage" should be followed during handling in order to minimise risks to
persons using the product in the workplace. Also, avoid contact or contamination of product with incompatible
materials listed in Section 10.
Storage: Note that this product is combustible and therefore, for Storage, meets the definition of Dangerous Goods
in some states. If you store large quantities (tonnes) of such products, we suggest that you consult your state's
Dangerous Goods authority in order to clarify your obligations regarding their storage.
Protect this product from light. Store in the closed original container in a dry, cool, well-ventilated area out of direct
sunlight. Make sure that the product does not come into contact with substances listed under "Incompatibilities" in
Section 10. Some liquid preparations settle or separate on standing and may require stirring before use. Check
packaging - there may be further storage instructions on the label.
Section 8 - Exposure Controls and Personal Protection
The following Australian Standards will provide general advice regarding safety clothing and equipment:
Respiratory equipment: AS/NZS 1715, Protective Gloves: AS 2161, Industrial Clothing: AS2919, Industrial Eye
Protection: AS1336 and AS/NZS 1337, Occupational Protective Footwear: AS/NZS2210.
TWA (mg/m3) STEL (mg/m3)
ASCC Exposure limits
Exposure limits have not been established by ASCC for any of the significant ingredients in this product.
The ADI for Clethodim is set at 0.01mg/kg/day. The corresponding NOEL is set at 1mg/kg/day. ADI means
Acceptable Daily Intake and NOEL means No-observable-effect-level. Values taken from Australian ADI List, Dec
2005.
No special equipment is usually needed when occasionally handling small quantities. The following instructions are
for bulk handling or where regular exposure in an occupational setting occurs without proper containment systems.
Ventilation: No special ventilation requirements are normally necessary for this product. However make sure that
the work environment remains clean and that vapours and mists are minimised.
Eye Protection: Protective glasses or goggles should be worn when this product is being used. Failure to protect
your eyes may cause them harm. Emergency eye wash facilities are also recommended in an area close to where
this product is being used.
Skin Protection: Prevent skin contact by wearing impervious gloves, clothes and, preferably, apron. Make sure that
all skin areas are covered. See below for suitable material types.
Protective Material Types: We suggest that protective clothing be made from the following materials: rubber,
PVC.
Respirator: Usually, no respirator is necessary when using this product. However, if you have any doubts consult
the Australian Standard mentioned above. Otherwise, not normally necessary.
Eyebaths or eyewash stations and safety deluge showers should be provided near to where this product is being
used.
Section 9 - Physical and Chemical Properties:
Physical Description & colour: Brown-amber coloured liquid.
MATERIAL SAFETY DATA SHEET
Issued by: Ospray Pty Ltd Freecall 1800 624 597 (Business hours)
Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)
Product Name: Ospray Clethodim 240 EC Selective Herbicide
Page: 4 of 6
This revision issued: September, 2006
Odour: Characteristic aromatic hydrocarbon odour.
Boiling Point: Not available.
Freezing/Melting Point: No specific data. Liquid at normal temperatures.
Volatiles: No data.
Vapour Pressure: No data.
Vapour Density: No data.
Specific Gravity: 0.95 approx at 20掳C
Water Solubility: Emulsifiable.
pH: Approx 3.5 (5% water emulsion)
Volatility: No data.
Odour Threshold: No data.
Evaporation Rate: No data.
Coeff Oil/water Distribution: No data
Autoignition temp: No data.
Section 10 - Stability and Reactivity
Reactivity: This product is unlikely to react or decompose under normal storage conditions. However, if you have
any doubts, contact the supplier for advice on shelf life properties.
Conditions to Avoid: Protect this product from light. Store in the closed original container in a dry, cool, well-
ventilated area out of direct sunlight.
Incompatibilities: strong acids, strong bases, strong oxidising agents.
Fire Decomposition: Carbon dioxide, and if combustion is incomplete, carbon monoxide and smoke. Oxides of
sulfur (sulfur dioxide is a respiratory hazard) and other sulfur compounds. Most will have a foul odour. Water. Carbon
monoxide poisoning produces headache, weakness, nausea, dizziness, confusion, dimness of vision, disturbance of
judgment, and unconsciousness followed by coma and death.
Polymerisation: This product will not undergo polymerisation reactions.
Section 11 - Toxicological Information
Toxicity: An information profile for Clethodim is available at http://extoxnet.orst.edu/pips/ghindex.html
Acute Toxicity: Clethodim is harmful by ingestion. The reported oral LD50 is 1,630 mg/kg and 1,360 mg/kg in male
and female rats, respectively. Clethodim is practically non-toxic by dermal absorption. The reported dermal LD50 is
greater than 5,000 mg/kg. The technical product did not cause skin irritation in the rabbit, but formulation caused
moderate skin as well as eye irritation in the rabbit. Eye irritation was reversible within 8-21 days. No data regarding
skin sensitization or eye irritation were available for the technical product. Clethodim is practically non-toxic by the
inhalation route. The reported rodent 4-hour inhalation LC50 for Clethodim technical is greater than 3.9 mg/L. Effects
of acute exposure to Clethodim or formulated products may include eye or skin irritation or central nervous system
effects, e.g., salivation, decreased motor activity, incoordination, unsteady gait and hyperactivity. These latter effects
may be in large measure due to the aromatic constituents of the formulation, as these effects commonly occur upon
exposure to such compounds.
Chronic Toxicity: In a one-year feeding study of dogs, doses of 75 mg/kg/day resulted in increased relative and
absolute liver weights, with anaemia-like alterations in blood chemistry such as reduced haemoglobin, erythrocyte and
hematocrit counts. In a two-year chronic study of rats, no compound-related effects on the structure and function of
the liver were observed, and no changes in liver weights were observed at the highest dose tested, approximately 100
mg/kg/day. Reduced body weight gain was observed in another study on rats at 350 mg/kg/day, but not at 100
mg/kg/day, over an unspecified period.
Reproductive Effects: No effects on fertility, length of gestation or growth and development of offspring were
observed at doses up to and including the highest dose tested, 263 mg/kg/day.
Teratogenic Effects: Data suggests that while there have been documented teratological effects in animal studies,
such effects are unlikely in humans under normal conditions of exposure.
Mutagenic Effects: The available data for mutagenicity and genotoxicity yield no evidence for mutagenic or
genotoxic activity.
Carcinogenic Effects: No carcinogenic effects were observed in mice administered Clethodim at doses of 24
mg/kg/day over an 18 month period. Based on the available data, it appears that Clethodim is not carcinogenic.
Organ Toxicity: The liver was the primary organ affected in chronic animal studies. Although potential effects
associated with acute exposure are reported to include central nervous system effects, no available chronic data
pointed to such effects.
Fate in Humans & Animals: Clethodim is readily absorbed in the gastrointestinal tract, with approximately 90%
absorption of oral doses. It is rapidly metabolized and eliminated (primarily sulfoxide metabolites, ca 63%) with less
than 1% recoverable unchanged.
MATERIAL SAFETY DATA SHEET
Issued by: Ospray Pty Ltd Freecall 1800 624 597 (Business hours)
Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)
Product Name: Ospray Clethodim 240 EC Selective Herbicide
Page: 5 of 6
This revision issued: September, 2006
Section 12 - Ecological Information
Effects on Birds: Clethodim is practically non-toxic to birds. Under likely conditions of use, it is unlikely to pose a
hazard to avian species.
Effects on Aquatic Organisms: Clethodim is slightly toxic to fish and aquatic invertebrate species. No effects were
seen at concentrations of 5.5 mg/L in Daphnia. No significant bioaccumulation has been observed in fish. Under likely
conditions of use, it is unlikely to pose a hazard to aquatic species.
Effects on Other Animals (Nontarget species): Clethodim is practically non-toxic to honeybees with reported LD50s of
greater than 100 碌g/bee for both the technical product and formulated product. EPA has stated that "available wildlife
data indicate that the proposed uses on cotton and soybeans will result in minimal hazard to nontarget and
endangered beneficial insect, avian and freshwater fish and mammalian species". Clethodim is selectively toxic to
plants, affecting only grass species.
ENVIRONMENTAL FATE
Breakdown of Chemical in Soil and Groundwater: Clethodim is of low persistence in most soils with a reported half-life
of approximately 3 days. Breakdown is mainly by aerobic processes, although photolysis may make some
contribution.
Breakdown of Chemical in Surface Water: Clethodim may be highly persistent in the aquatic environment. Reported
half-lives for Clethodim in the aquatic environment are 128 days in the aqueous phase and 214 days in the sediment.
The reported hydrolysis half-life at pH 7-9 is approximately 300 days.
Breakdown of Chemical in Vegetation: Clethodim is rapidly degraded on the leaf surfaces by an acid-catalysed
reaction and photolysis. Remaining Clethodim will rapidly penetrate the cuticle and enter the plant.
Section 13 - Disposal Considerations
Disposal: There are many pieces of legislation covering waste disposal and they differ in each state and territory, so
each user must refer to laws operating in their area. In some areas, certain wastes must be tracked. The Hierarchy of
Controls seems to be common - the user should investigate: Reduce, Reuse, and Recycle and only if all else fails
should disposal be considered. Note that properties of a product may change in use, so that the following suggestions
may not always be appropriate. The following may help you in properly addressing this matter for this product. Special
help is available for the disposal of Agricultural Chemicals. The product label will give general advice regarding
disposal of small quantities, and how to cleanse containers. However, for help with the collection of unwanted rural
chemicals, contact ChemClear 1800 008 182 http://www.chemclear.com.au/ and for help with the disposal of empty
drums, contact DrumMuster http://www.drummuster.com.au/ where you will find contact details for your area.
Section 14 - Transport Information
ADG Code: This product is not classified as a Dangerous Good. No special transport conditions are necessary
unless required by other regulations.
Section 15 - Regulatory Information
AICS: All of the significant ingredients in this formulation are compliant with NICNAS regulations.
The following ingredients: Clethodim, Aromatic hydrocarbons, are mentioned in the SUSDP.
Section 16 - Other Information
This MSDS contains only safety-related information. For other data see product literature.
Acronyms:
ADG Code Australian Code for the Transport of Dangerous Goods by Road and Rail
AICS Australian Inventory of Chemical Substances
ASCC Office of the Australian Safety and Compensation Council
CAS Number Chemical Abstracts Service Registry Number
Hazchem Code Emergency action code of numbers and letters that provide information to
emergency services especially firefighters
IARC International Agency for Research on Cancer
NOS Not otherwise specified
NTP National Toxicology Program (USA)
R-Phrase Risk Phrase
SUSDP Standard for the Uniform Scheduling of Drugs & Poisons
UN Number United Nations Number
THIS MSDS SUMMARISES OUR BEST KNOWLEDGE OF THE HEALTH AND SAFETY HAZARD INFORMATION OF THE PRODUCT AND
HOW TO SAFELY HANDLE AND USE THE PRODUCT IN THE WORKPLACE. EACH USER MUST REVIEW THIS MSDS IN THE CONTEXT OF
HOW THE PRODUCT WILL BE HANDLED AND USED IN THE WORKPLACE.
IF CLARIFICATION OR FURTHER INFORMATION IS NEEDED TO ENSURE THAT AN APPROPRIATE RISK ASSESSMENT CAN BE MADE,
THE USER SHOULD CONTACT THIS COMPANY SO WE CAN ATTEMPT TO OBTAIN ADDITIONAL INFORMATION FROM OUR SUPPLIERS
MATERIAL SAFETY DATA SHEET
Issued by: Ospray Pty Ltd Freecall 1800 624 597 (Business hours)
Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)
Product Name: Ospray Clethodim 240 EC Selective Herbicide
Page: 6 of 6
This revision issued: September, 2006
OUR RESPONSIBILITY FOR PRODUCTS SOLD IS SUBJECT TO OUR STANDARD TERMS AND CONDITIONS, A COPY OF WHICH IS SENT
TO OUR CUSTOMERS AND IS ALSO AVAILABLE ON REQUEST.
Please read all labels carefully before using product.
This MSDS is prepared in accord with the ASCC document 鈥淣ational Code of Practice for the Preparation
of Material Safety Data Sheets鈥? 2nd Edition [NOHSC:2011(2003)]
Copyright 漏 Kilford & Kilford Pty Ltd, September, 2006.
http://www.kilford.com.au/ Phone (02)9251 4532
MATERIAL SAFETY DATA SHEET
Issued by: Ospray Pty Ltd Freecall 1800 624 597 (Business hours)
Poisons Information Centre: 13 1126 from anywhere in Australia, (0800 764 766 in New Zealand)
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