The MSDS format adheres to the standards and regulatory requirements
of the United States and may not meet regulatory requirements
in other countries.
DuPont Page 1
Material Safety Data Sheet
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"DuPont" "VELPAR" "K-4" MAX HERBICIDE
M0000639 Revised 21-DEC-2007
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CHEMICAL PRODUCT/COMPANY IDENTIFICATION
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Material Identification
"VELPAR" is a registered trademark of DuPont.
"DuPont", "K-4" are trademarks of DuPont.
Tradenames and Synonyms
VELPAR K-4 MAX
DPX-KQG34
VELPAR DF (HEXAZINONE) COMPONENT
KARMEX XP (DIURON) COMPONENT
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information : 1-800-441-7515 (outside the U.S.
302-774-1000)
Transport Emergency : CHEMTREC 1-800-424-9300(outside U.S.
703-527-3887)
Medical Emergency : 1-800-441-3637 (outside the U.S.
302-774-1000)
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COMPOSITION/INFORMATION ON INGREDIENTS
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Components
Material CAS Number %
*DIURON 330-54-1 61.5
3-(3,4-DICHLOROPHENYL)-1,1-DIMETHYLUREA
*HEXAZINONE 51235-04-2 17.3
[3-CYCLOHEXYL-6-(DIMETHYLAMINO)-1-METHYL-1,3,5-
TRIAZINE-2,4(1H,3H)-DIONE]
INERT INGREDIENTS 21.2
* Disclosure as a toxic chemical is required under Section 313 of
Title III of the Superfund Amendments and Reauthorization Act of 1986
and 40 CFR part 372.
M0000639 DuPont Page 2
Material Safety Data Sheet
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HAZARDS IDENTIFICATION
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Emergency Overview
DANGER! CAUSES EYE DAMAGE. Corrosive, causes irreversible
eye damage. Harmful if swallowed. Do not get in eyes or
on clothing. Avoid contact with skin. Wash thoroughly with
soap and water after handling.
Potential Health Effects
Based on data from animal testing, eye contact may cause
eye irritation with discomfort, tearing, or blurring of
vision.
Based on data from animal testing, skin contact may cause
skin irritation with discomfort or rash.
Based on data from animal testing, ingestion of large
amounts may cause alterations in red blood cell counts
and/or anemia, spleen effects and liver effects.
Carcinogenicity Information
The following components are listed by IARC, NTP, OSHA or ACGIH as
carcinogens.
Material IARC NTP OSHA ACGIH
DIURON A4
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FIRST AID MEASURES
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First Aid
IF IN EYES: Hold eye open and rinse slowly and gently
with water for 15-20 minutes. Remove contact lenses, if
present, after the first 5 minutes, then continue rinsing
eye. Call a poison control center or doctor for treatment
advice.
IF ON SKIN OR CLOTHING: Take off contaminated clothing.
Rinse skin immediately with plenty of water for 15-20
minutes. Call a poison control center or doctor for
treatment advice.
IF SWALLOWED: Call a poison control center or doctor
immediately for treatment advice. Have person sip a glass
of water if able to swallow. Do not induce vomiting unless
told to do so by a poison control center or doctor. Do not
give anything by mouth to an unconscious person.
IF INHALED: No specific intervention is indicated as the
product is not likely to be hazardous by inhalation.
Consult a physician if necessary.
M0000639 DuPont Page 3
Material Safety Data Sheet
(FIRST AID MEASURES - Continued)
Have the product container or label with you when calling a
poison control center or doctor, or going for treatment.
You may also contact 1-800-441-3637 for medical emergencies
involving this product.
Notes to Physicians
Probable mucosal damage may contraindicate the use of
gastric lavage.
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FIRE FIGHTING MEASURES
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Flammable Properties
DIURON:
Flammable limits in Air, % by volume
LEL : 0.096 g/L
Autoignition : 440掳C (824掳F)
HEXAZINONE:
Autoignition : >350掳C (>662掳F)
Like most organic powders or crystals, under severe dusting
conditions, this material may form explosive mixtures in
air. May be ignited by heat or open flame. Hazardous
gases/vapors produced in fire are highly toxic.
Extinguishing Media
Water, Water Spray, Foam, Dry Chemical, CO2.
Fire Fighting Instructions
Evacuate personnel to a safe area. Keep personnel removed and
upwind of fire.
Wear self-contained breathing apparatus. Wear full
protective equipment Runoff from fire control may be a
pollution hazard. Use water spray. Cool tank/container
with water spray.
If area is exposed to fire and conditions permit, let fire
burn itself out. Burning chemicals may produce by-products
more toxic than the original material.
M0000639 DuPont Page 4
Material Safety Data Sheet
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ACCIDENTAL RELEASE MEASURES
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Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Emergency Response - Chemical resistant coveralls,
waterproof gloves, waterproof boots and face / eye
protection. If dusting occurs use NIOSH approved respirator
protection.
Initial Containment
Dike spill. Prevent material from entering sewers, waterways, or
low areas.
Spill Clean Up
Shovel or sweep up. Never return to container for reuse.
Scoop into bags or boxes with plastic or aluminum shovel.
For minor spills, leaks, etc., follow all precautions
indicated on the label and clean up immediately. Take
special care to avoid contamination of equipment and
facilities during cleanup procedures and disposal of wastes.
In the event of a major spill, fire or other emergency, call
1-800-441-3637 day or night.
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HANDLING AND STORAGE
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Handling (Personnel)
USERS SHOULD: Wash hands before eating, drinking, chewing gum,
using tobacco or using the toilet.
Remove clothing immediately if pesticide gets inside. Then wash
thoroughly and put on clean clothing.
Remove personal protective equipment immediately after handling
this product. Wash the outside of gloves before removing. As
soon as possible, wash thoroughly and change into clean clothing.
Handling (Physical Aspects)
Avoid dust generation.
M0000639 DuPont Page 5
Material Safety Data Sheet
(HANDLING AND STORAGE - Continued)
Storage
Do not contaminate water, food or feed by storage or
disposal.
Store product in original container only. Store in a cool,
dry place.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Engineering Controls
When handlers use closed systems, enclosed cabs or aircraft
in a manner that meets the requirements listed in the Worker
Protection Standard (WPS) for agricultural pesticides
[40 CFR 170.240 (d)(4-6)], the handler PPE requirements may
be reduced or modified as specified in the WPS.
Pilots must use an enclosed cockpit that meets the
requirements listed in the Worker Protection Standard
(WPS) for agricultural pesticides [40 CFR
170.240(d)(6)].
Flaggers supporting aerial applications must use an
enclosed cab that meets the definition in the Worker
Protection Standard (WPS) for agricultural pesticides [40
CFR 170.240(d)(5)] for dermal protection.
Personal Protective Equipment
Some of the materials that are chemical-resistant to this
product are listed below. If you want more options, follow
the instructions for Category A on an EPA chemical-
resistance category selection chart.
Pilots, flaggers and groundboom applicators must wear:
- Long-sleeved shirt and long pants.
- Shoes plus socks.
- Protective eyewear.
Mixers, loaders, other applicators, and other handlers
must wear:
- Long-sleeved shirt and long pants.
- Shoes plus socks.
- Protective eyewear.
- Chemical resistant gloves made of any waterproof
material such as polyethylene or polyvinylchloride.
- A NIOSH approved dust/mist filtering respirator with
any N, R, P, or HE filter or with approval number
prefix TC-21C.
- Chemical resistant apron when mixing, loading, or
cleaning equipment or spills.
M0000639 DuPont Page 6
Material Safety Data Sheet
(EXPOSURE CONTROLS/PERSONAL PROTECTION - Continued)
Discard clothing and other absorbent materials that have
been drenched or heavily contaminated with this product鈥檚
concentrate. Do not reuse them. Follow manufacturer鈥檚
instructions for cleaning/maintaining PPE. If no such
instructions for washables, use detergent and hot water.
Keep and wash PPE separately from other laundry.
Do not apply this product in a way that will contact workers
or other persons, either directly or through drift. Only
protected handlers may be in the area during application.
PPE required for early entry to treated areas that is
permitted under the Worker Protection Standard and that
involves contact with anything that has been treated, such
as plants, soil, or water, is:
- Coveralls.
- Shoes plus socks.
- Chemical resistant gloves made of any waterproof
material.
Exposure Guidelines
Applicable Exposure Limits
DIURON
PEL (OSHA) : None Established
TLV (ACGIH) : 10 mg/m3, 8 Hr. TWA, A4
AEL * (DuPont) : 1 mg/m3, 8 & 12 Hr. TWA, total dust
HEXAZINONE
PEL (OSHA) : None Established
TLV (ACGIH) : None Established
AEL * (DuPont) : 10 mg/m3, 8 Hr. TWA
* AEL is DuPont鈥檚 Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
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PHYSICAL AND CHEMICAL PROPERTIES
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Physical Data
Color : Light Brown
Physical State : Solid, granules
Odor : Slight
pH : 8.0
Bulk Density (tap) : 0.714 g/mL
M0000639 DuPont Page 7
Material Safety Data Sheet
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STABILITY AND REACTIVITY
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Chemical Stability
Stable at normal temperatures and storage conditions.
Incompatibility with Other Materials
DIURON : None reasonably foreseeable.
HEXAZINONE : Incompatible with strong acids or bases.
Decomposition
DIURON:
Decomposition temperature: 180-190掳C (356-374掳F)
HEXAZINONE:
Decomposition will not occur.
Polymerization
Polymerization will not occur.
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TOXICOLOGICAL INFORMATION
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Animal Data
Velpar DF
Oral LD50: 1310 mg/kg in rats
Dermal LD50: > 5000 mg/kg in rabbits
Inhalation 4-hour LC50: 5.2 mg/L
Velpar DF is a skin irritant, is corrosive to the eye, but is not
a skin sensitizer in animals.
HEXAZINONE
Repeated skin applications indicated no irritation or systemic
activity.
Repeated dosing by ingestion of excessive dietary levels of
Hexazinone resulted in weight loss, alterations in liver weights
alterations in blood chemical measurements, and alterations in
enzyme activities. No evidence of pathological organ damage was
observed. Long-term dosing produced decreased weight gain,
alterations in hematology, clinical chemistry, and blood enzyme
levels, increased liver weights in some species, and pathological
liver changes.
Animal data showed that chronic, excessive dietary exposure to
Hexazinone produced a slight, equivocal increase in liver tumors
in female mice.
M0000639 DuPont Page 8
Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
Animal data show developmental effects only at exposure levels
producing other toxic effects in the adult animal. Animal testing
indicates Hexazinone does not have reproductive effects. The
weight of evidence from a battery of cell culture and laboratory
animal tests indicates Hexazinone does not cause genetic toxicity.
KARMEX XP (Diuron Component)
Oral LD50: > 5,000 mg/kg in rats
Dermal LD50: > 5,000 mg/kg in rabbits
Inhalation LC50, 4 hr: > 2.02 mg/L in rats
KARMEX XP is a moderate eye irritant, and a mild skin
irritant. It is not a skin sensitizer in animals.
DIURON
Repeated ingestion of Diuron led to increased hemolysis
(destruction) of red blood cells and hemolytic anemia after
continued exposure to high doses. Secondary effects as a
result of excessive red blood cell hemolysis included
enlarged spleens, pigment deposits in the spleen, changes in
the bone marrow and kidney. Decreased body weights were
also related to repeated ingestion of high doses of Diuron.
In addition to the effects described above, long-term
effects observed in rodents after repeated ingestion of high
doses also included thickening of the urinary bladder and
kidney epithelium and liver toxicity. In chronic feeding
studies, an increase in urinary bladder and renal pelvic
tumors was observed in high-dose rats. A borderline increase
in mammary tumors was observed in high-dose female mice,
which is considered equivocal.
The weight of the evidence indicates that Diuron does not
produce genetic damage in bacterial or mammalian cell
cultures or in animals. Diuron is not considered a
developmental toxicant. There was no evidence of
developmental toxicity in rabbits. In rats, developmental
effects occurred at doses higher than those which produced
maternal toxicity. Testing in rats demonstrate no
reproductive toxicity.
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ECOLOGICAL INFORMATION
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# Ecotoxicological Information
AQUATIC TOXICITY:
DIURON
96-Hour LC50 - Bluegill sunfish: 25 mg/L
96-Hour LC50 - Rainbow trout: 14.7 mg/L
48-Hour EC50 - Daphnia magna: 1.4 mg/L
EC50 - Algae - 0.018 mg/L
M0000639 DuPont Page 9
Material Safety Data Sheet
(ECOLOGICAL INFORMATION - Continued)
AVIAN TOXICITY:
LD50 - Bobwhite Quail: 1104 mg/kg
AQUATIC TOXICITY:
HEXAZINONE
96-Hour LC50 - Fathead minnows: 274 mg/L
96-Hour LC50 - Bluegill sunfish: > 370 mg/L
96-Hour LC50 - Rainbow trout: > 320 mg/L
AVIAN TOXICITY:
LD50 - Bobwhite quail: 2258 mg/kg
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DISPOSAL CONSIDERATIONS
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Waste Disposal
Do not contaminate water, food, or feed by storage or
disposal. Waste resulting from the use of this product may
be disposed of on the site or at an approved waste disposal
facility.
ENVIRONMENTAL HAZARDS
For terrestrial uses, do not apply directly to water, or
to areas where surface water is present or to intertidal
areas below the mean high water mark. Do not contaminate
water when cleaning equipment or disposing of equipment
washwaters.
The active ingredient, hexazinone, in this product is known
to leach through soil into ground water under certain
conditions as a result of agricultural use. Use of this
chemical in areas where soils are permeable, particularly
where the water table is shallow, may result in ground-water
contamination.
Container Disposal
For Plastic Containers: Triple rinse (or equivalent). Then
offer for recycling or reconditioning, or puncture and
dispose of in a sanitary landfill, or incineration, or, if
allowed by State and local authorities, by burning. If
burned, stay out of smoke.
For Fiber Sacks: Completely empty fiber sack by shaking and
tapping sides and bottom to loosen clinging particles.
Empty residue into manufacturing or application equipment.
Then dispose of sack in a sanitary landfill or by
incineration if allowed by State and local authorities.
For Fiber Drums With Liners: Completely empty liner by
shaking and tapping sides and bottom to loosen clinging
particles. Empty residue into application equipment. Then
dispose of liner in a sanitary landfill or by incineration
M0000639 DuPont Page 10
Material Safety Data Sheet
(DISPOSAL CONSIDERATIONS - Continued)
if allowed by State and local authorities. If drum is
contaminated and cannot be reused, dispose of in the same
manner.
For Paper and Plastic Bags: Completely empty bag into
application equipment. Then dispose of empty bag in a
sanitary landfill or by incineration, or, if allowed by
State and local authorities, by burning. If burned, stay
out of smoke.
Container Refilling and Disposal (For Containers up to
250 gal): Refer to the product label for instructions.
Container Disposal for Bulk Containers: Refer to the
product label for instructions.
The container must only be refilled with this pesticide
product. DO NO REUSE THE CONTAINER FOR ANY OTHER PURPOSE.
Do not transport if the container is damaged or leaking.
Disposal of the container must be in compliance with State
and local regulations.
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TRANSPORTATION INFORMATION
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Shipping Information
DOT
Proper Shipping Name : Not Regulated if <100 lbs./pkg. (See
*NOTE)
DOT/IMO
Proper Shipping Name : Not Regulated by IMO
*NOTE: IF 100 lbs. Diuron or more Per Package:
Proper Shipping Name : Environmentally Hazardous Substance,
Solid, N.O.S. (Diuron)
Hazard Class :9
UN/NA No. : UN 3077
Packaging Group : III
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REGULATORY INFORMATION
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U.S. Federal Regulations
Superfund reportable discharge = 100 lb.
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute : Yes
Chronic : Yes
Fire : No
Reactivity : No
M0000639 DuPont Page 11
Material Safety Data Sheet
(REGULATORY INFORMATION - Continued)
Pressure : No
In the United States this product is regulated by the US
Environmental Protection Agency under the Federal Insecticide,
Fungicide and Rodenticide Act. It is a violation of federal law
to use this product in a manner inconsistent with its labeling.
EPA Reg. No. 352-663
ADDITIONAL REGULATORY INFORMATION
SARA/CERCLA Reportable Quantity:
Diuron (100 lbs.)
State Regulations (U.S.)
*** CALIFORNIA PROP 65 ***
THIS PRODUCT CONTAINS DIURON, A CHEMICAL KNOWN TO THE STATE
OF CALIFORNIA TO CAUSE CANCER IN LABORATORY ANIMALS.
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OTHER INFORMATION
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NFPA, NPCA-HMIS
NFPA Rating
Health : 2
Flammability : 1
Reactivity : 0
NPCA-HMIS Rating
Health : 2
Flammability : 1
Reactivity : 0
Personal Protection rating to be supplied by user depending
on use conditions.
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The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Responsibility for MSDS: DuPont Crop Protection
Address : Wilmington, DE 19898
Telephone : 1-888-638-7668
# Indicates updated section.
This information is based upon technical information believed to be
reliable. It is subject to revision as additional knowledge and
experience is gained.
End of MSDS
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