SAFETY DATA SHEET
STREPTOZOTOCIN Page 1
Issued: 08/05/2007
Revision No: 1
1. IDENTIFICATION OF THE SUBSTANCE / PREPARATION AND OF THE COMPANY / UNDERTAKING
Product name: STREPTOZOTOCIN
CAS number: 18883-66-4
BIS4356
Product code:
Use / description of product: Toxic. powder
Company name: Apollo Scientific Ltd
Bredbury, Stockport, SK6 2QR,Tel 0161 406 0505
2. COMPOSITION / INFORMATION ON INGREDIENTS
Hazardous ingredients: STREPTOZOTOCIN >90%
3. HAZARDS IDENTIFICATION
Main hazards: Harmful if swallowed. May cause cancer. May cause heritable genetic damage. May cause
harm to the unborn child.
4. FIRST AID MEASURES (SYMPTOMS)
Skin contact: There may be irritation and redness at the site of contact.
Eye contact: There may be pain and redness.
Ingestion: There may be soreness and redness of the mouth and throat. Severe poisoning can cause
unconsciousness and severe and persistent nausea and vomiting. Severe poisoning can cause
shock, unconsciousness and convulsions. Severe poisoning can cause vision to be blurred or
blindness, severe headache and rapid gasping breathing.
Inhalation: There may be shortness of breath with a burning sensation in the throat. Absorption through the
lungs can occur causing symptoms similar to those of ingestion. Nausea and stomach pain may
occur.
4. FIRST AID MEASURES (ACTION)
Skin contact: Remove all contaminated clothes and footwear immediately unless stuck to skin. Drench the
affected skin with running water for 10 minutes or longer if substance is still on skin. Transfer to
hospital if there are burns or symptoms of poisoning.
Eye contact: Bathe the eye with running water for 15 minutes. Transfer to hospital for specialist examination.
Ingestion: Do not induce vomiting. If conscious, give half a litre of water to drink immediately. If
unconscious and breathing is OK, place in the recovery position. Transfer to hospital as soon
as possible.
Inhalation: Remove casualty from exposure ensuring one's own safety whilst doing so. Transfer to hospital
as soon as possible.
5. FIRE-FIGHTING MEASURES
Extinguishing media: Suitable extinguishing media for the surrounding fire should be used. Carbon dioxide. Dry
chemical powder.
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Exposure hazards: Toxic. In combustion emits toxic fumes.
Protection of fire-fighters: Wear self-contained breathing apparatus. Wear protective clothing to prevent contact with skin
and eyes.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions: Notify the police and fire brigade immediately. If outside keep bystanders upwind and away from
danger point. Mark out the contaminated area with signs and prevent access to unauthorised
personnel. Do not attempt to take action without suitable protective clothing - see section 8 of
SDS. Do not create dust.
Environmental precautions: Do not discharge into drains or rivers.
Clean-up procedures: Clean-up should be dealt with only by qualified personnel familiar with the specific substance.
Transfer to a closable, labelled salvage container for disposal by an appropriate method.
7. HANDLING AND STORAGE
Handling requirements: Avoid the formation or spread of dust in the air. Ensure there is sufficient ventilation of the area.
only use in fume hood
Storage conditions: Keep container tightly closed. Store at +4 C or below
Suitable packaging: Must only be kept in original packaging.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering measures: Ensure there is sufficient ventilation of the area.
Respiratory protection: Self-contained breathing apparatus must be available in case of emergency. Respiratory
protective device with particle filter.
Hand protection: Protective gloves.
Eye protection: Safety glasses. Ensure eye bath is to hand.
Skin protection: Protective clothing.
9. PHYSICAL AND CHEMICAL PROPERTIES
State: Powder
Solubility in water: Soluble
Melting point/range掳C: 115
10. STABILITY AND REACTIVITY
Stability: Stable under normal conditions.
Conditions to avoid: Heat.
Materials to avoid: Strong oxidising agents. Strong acids.
Haz. decomp. products: In combustion emits toxic fumes.
11. TOXICOLOGICAL INFORMATION
Chronic toxicity: MAY BE HARMFUL BY INHALATION, INGESTION, OR SKIN ABSORPTION.
Routes of exposure: Refer to section 4 of SDS for routes of exposure and corresponding symptoms. MAY BE
HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN
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STREPTOZOTOCIN Page 3
12. ECOLOGICAL INFORMATION
Mobility: Data not yet known
Persistence and degradability: No data available.
Bioaccumulative potential: No data available.
Other adverse effects: No data available.
13. DISPOSAL CONSIDERATIONS
Disposal operations: MATERIAL SHOULD BE DISPOSED OF IN ACCORDANCE WITH LOCAL, STATE AND
FEDERAL REGULATIONS
Disposal of packaging: Dispose of as special waste in compliance with local and national regulations Observe all
federal, state and local environmental regulations.
NB: The user's attention is drawn to the possible existence of regional or national regulations
regarding disposal.
14. TRANSPORT INFORMATION
ADR / RID
UN no: 3249 ADR Class: 6.1
Packing group: III Classification code: T2
Shipping name: MEDICINE, SOLID, TOXIC, N.O.S.
Labelling: 6.1 Hazard ID no: 60
IMDG / IMO
UN no: 3249 Class: 6.1
Packing group: III EmS: F-A,S-A
Marine pollutant: . Labelling: 6.1
IATA / ICAO
UN no: 3249 Class: 6.1
Packing group: III Packing instructions: 613(P&CA); 615(CAO)
Labelling: 6.1
15. REGULATORY INFORMATION
Hazard symbols: Toxic.
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STREPTOZOTOCIN Page 4
Risk phrases: R22: Harmful if swallowed.
R45: May cause cancer.
R46: May cause heritable genetic damage.
R61: May cause harm to the unborn child.
Safety phrases: S36/37/39: Wear suitable protective clothing, gloves and eye / face protection.
S38: In case of insufficient ventilation, wear suitable respiratory equipment.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label
where possible).
S53: Avoid exposure - obtain special instructions before use.
Restricted to professional users.
Precautionary phrases:
Note: The regulatory information given above only indicates the principal regulations specifically
applicable to the product described in the safety data sheet. The user's attention is drawn to
the possible existence of additional provisions which complete these regulations. Refer to all
applicable national, international and local regulations or provisions.
16. OTHER INFORMATION
Legal disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall
be used only as a guide. This company shall not be held liable for any damage resulting from
handling or from contact with the above product.
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