SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 02/18/2008
Date Updated: 02/02/2007
Version 1.5
Section 1 - Product and Company Information
Product Name TERT-BUTYL ISOCYANIDE, 98%
Product Number 260630
Brand ALDRICH
Company Sigma-Aldrich
Address 3050 Spruce Street
SAINT LOUIS MO 63103 US
Technical Phone: 800-325-5832
Fax: 800-325-5052
Emergency Phone: 314-776-6555
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
TERT-BUTYL ISOCYANIDE 7188-38-7 No
Formula C5H9N
Synonyms tert-Butylisonitrile * 2-Isocyano-2-methylpropane
* Propane, 2-isocyano-2-methyl- (9CI) * TBIN
RTECS Number: EQ7102500
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Flammable (USA) Highly Flammable (EU). Highly Toxic (USA) Toxic
(EU).
Toxic by inhalation.
HMIS RATING
HEALTH: 2
FLAMMABILITY: 3
REACTIVITY: 0
NFPA RATING
HEALTH: 2
FLAMMABILITY: 3
REACTIVITY: 0
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
Section 5 - Fire Fighting Measures
FLAMMABLE HAZARDS
Flammable Hazards: Yes
EXPLOSION HAZARDS
Vapor may travel considerable distance to source of ignition and
flash back. Container explosion may occur under fire conditions.
Forms explosive mixtures in air.
FLASH POINT
< 59 藲F < 15 藲C Method: closed cup
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: For small (incipient) fires, use media such as
"alcohol" foam, dry chemical, or carbon dioxide. For large
fires, apply water from as far as possible. Use very large
quantities (flooding) of water applied as a mist or spray; solid
streams of water may be ineffective. Cool all affected
containers with flooding quantities of water.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Vapor may travel considerable distance to source of ignition and
flash back.
Specific Method(s) of Fire Fighting: Use water spray to cool
fire-exposed containers.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
Section 7 - Handling and Storage
ALDRICH - 260630 www.sigma-aldrich.com Page 2
HANDLING
User Exposure: Do not breathe vapor. Avoid contact with eyes,
skin, and clothing. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep container closed. Keep away from heat, sparks,
and open flame.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Use only in a
chemical fume hood.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Use respirators and components tested and approved
under appropriate government standards such as NIOSH (US) or CEN
(EU). Where risk assessment shows air-purifying respirators are
appropriate use a full-face respirator with multi-purpose
combination (US) or type ABEK (EN 14387) respirator cartridges as
a backup to engineering controls. If the respirator is the sole
means of protection, use a full-face supplied air respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Remove and wash contaminated
clothing promptly.
Section 9 - Physical/Chemical Properties
Appearance Color: Colorless
Form: Clear liquid
Property Value At Temperature or Pressure
Molecular Weight 83.13 AMU
pH N/A
BP/BP Range 90.0 - 92.0 藲C
MP/MP Range N/A
Freezing Point N/A
Vapor Pressure N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density 0.736 g/cm3
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point < 59 藲F < 15 藲C Method: closed cup
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index 1.376
Optical Rotation N/A
ALDRICH - 260630 www.sigma-aldrich.com Page 3
Miscellaneous Data N/A
Solubility N/A
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong acids, Strong bases, Strong oxidizing
agents, Strong reducing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide,
and nitrogen oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. Toxic if inhaled.
Ingestion: May be harmful if swallowed.
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
Nausea, headache, and vomiting. Exposure can cause:
TOXICITY DATA
Inhalation
Rat
710 mg/m3
LC50
Remarks: Behavioral:Change in motor activity (specific assay).
Inhalation
Mouse
377 mg/m3
LC50
Remarks: Behavioral:Change in motor activity (specific assay).
Section 12 - Ecological Information
No data available.
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Burn in a chemical incinerator equipped with an afterburner and
scrubber but exert extra care in igniting as this material is
highly flammable. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
ALDRICH - 260630 www.sigma-aldrich.com Page 4
DOT
Proper Shipping Name: Flammable liquids, n.o.s.
UN#: 1993
Class: 3
Packing Group: Packing Group II
Hazard Label: Flammable liquid
PIH: Not PIH
IATA
Proper Shipping Name: Flammable liquid, n.o.s.
IATA UN Number: 1993
Hazard Class: 3
Packing Group: II
Section 15 - Regulatory Information
EU ADDITIONAL CLASSIFICATION
Symbol of Danger: F-T
Indication of Danger: Highly Flammable. Toxic.
R: 11-23
Risk Statements: Highly flammable. Toxic by inhalation.
S: 16-45
Safety Statements: Keep away from sources of ignition - no
smoking. In case of accident or if you feel unwell, seek medical
advice immediately (show the label where possible).
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Flammable (USA) Highly Flammable (EU).
Highly Toxic (USA) Toxic (EU).
Risk Statements: Toxic by inhalation.
Safety Statements: Keep away from sources of ignition - no
smoking. In case of accident or if you feel unwell, seek medical
advice immediately (show the label where possible).
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: No
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2008 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
ALDRICH - 260630 www.sigma-aldrich.com Page 5
SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 02/18/2008
Date Updated: 09/06/2006
Version 1.0
Section 1 - Product and Company Information
Product Name SS BENZOIC ACID,1X2.5ML,CH2CL2,2000UG/ML
Product Number 8S61336
Brand SUPELCO
Company Sigma-Aldrich
Address 3050 Spruce Street
SAINT LOUIS MO 63103 US
Technical Phone: 800-325-5832
Fax: 800-325-5052
Emergency Phone: 314-776-6555
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
BENZOIC ACID IN METHYLENE CHLORIDE None Yes
Ingredient Name CAS # Percent SARA 313
BENZOIC ACID 65-85-0 0.2 No
METHANE, DICHLORO- 75-09-2 99.8 Yes
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Toxic (USA) Harmful (EU).
May cause cancer. Harmful if swallowed. Irritating to eyes,
respiratory system and skin.
Probable Carcinogen (US). Readily absorbed through skin. Calif.
Prop. 65 carcinogen. Target organ(s): Heart. Central nervous
system.
HMIS RATING
HEALTH: 2*
FLAMMABILITY: 1
REACTIVITY: 0
NFPA RATING
HEALTH: 2
FLAMMABILITY: 1
REACTIVITY: 0
*additional chronic hazards present.
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
Section 5 - Fire Fighting Measures
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: For small (incipient) fires, use media such as
"alcohol" foam, dry chemical, or carbon dioxide. For large
fires, apply water from as far as possible. Use very large
quantities (flooding) of water applied as a mist or spray; solid
streams of water may be ineffective. Cool all affected
containers with flooding quantities of water.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves. Wear disposable coveralls and discard them after
use.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe vapor. Do not get in eyes, on
skin, on clothing. Avoid prolonged or repeated exposure. For
protection and handling requirements consult CFR title 29 part
1910.1052.
STORAGE
Suitable: Store under inert gas. Keep tightly closed.
SUPELCO - 8S61336 www.sigma-aldrich.com Page 2
Store at 2-8藲C
SPECIAL REQUIREMENTS
Store under inert gas.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Use respirators and components tested and approved
under appropriate government standards such as NIOSH (US) or CEN
(EU). Use supplied-air or SCBA respirators. Europe permits the use
of type AXBEK full-face cartridge respirators (EN 14387).
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
Section 9 - Physical/Chemical Properties
Appearance Physical State: Liquid
Property Value At Temperature or Pressure
Molecular Weight N/A
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Freezing Point N/A
Vapor Pressure N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density N/A
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
Solubility N/A
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
SUPELCO - 8S61336 www.sigma-aldrich.com Page 3
Stable: Stable.
Conditions to Avoid: Heat.
Materials to Avoid: Aluminum, Alkali metals.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Phosgene gas Carbon monoxide,
Carbon dioxide, Hydrogen chloride gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: Readily absorbed through skin. May be harmful
if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
TARGET ORGAN(S) OR SYSTEM(S)
Target organ: heart because methylene chloride is converted to
carbon monoxide in the body. Target organ: central nervous
system because of possible dizziness, headache, loss of
consciousness and death at high concentrations. Liver. Pancreas.
Blood.
SIGNS AND SYMPTOMS OF EXPOSURE
Paresthesia. CNS depression. Prolonged or repeated contact with
skin can cause defatting and dermatitis. Contact with eyes can
cause redness, tearing, and blurred vision. Ingestion may cause
gastrointestinal irritation. A simple asphyxiant, exposure can
cause anesthetic action, difficulty in breathing, headache, and
dizziness. Dichloromethane is metabolized in the body producing
carbon monoxide which increases and sustains carboxyhemoglobin
levels in the blood, reducing the oxygen-carrying capacity of
the blood. Drowsiness. Somnolence. Weakness. Increased liver
enzymes. Ingestion can cause gastrointestinal disorders, nausea,
and vomiting. Irregular breathing. Pulmonary edema. Effects may
be delayed. Conjunctivitis. Convulsions.
CONDITIONS AGGRAVATED BY EXPOSURE
Existing data suggests that methylene chloride may be a weak
mutagen in mammalian systems.
CHRONIC EXPOSURE - CARCINOGEN
Result: This product is or contains a component that has been
reported to be probably carcinogenic based on its IARC, OSHA,
ACGIH, NTP, or EPA classification.
IRIS/EPA CARCINOGEN LIST
Rating: Group B2
CHRONIC EXPOSURE - TERATOGEN
Result: Possible risk of congenital malformation in the fetus.
Section 12 - Ecological Information
No data available.
SUPELCO - 8S61336 www.sigma-aldrich.com Page 4
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: Dichloromethane solution
UN#: 1593
Class: 6.1
Packing Group: Packing Group III
Hazard Label: Toxic Substance
PIH: Not PIH
IATA
Proper Shipping Name: Dichloromethane solution
IATA UN Number: 1593
Hazard Class: 6.1
Packing Group: III
Section 15 - Regulatory Information
EU ADDITIONAL CLASSIFICATION
Symbol of Danger: Xn
Indication of Danger: Harmful.
R: 40
Risk Statements: Limited evidence of a carcinogenic effect.
S: 36/37
Safety Statements: Wear suitable protective clothing and gloves.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Toxic (USA) Harmful (EU).
Risk Statements: May cause cancer. Harmful if swallowed.
Irritating to eyes, respiratory system and skin.
Safety Statements: Avoid exposure - obtain special instructions
before use. In case of contact with eyes, rinse immediately with
plenty of water and seek medical advice. In case of accident or
if you feel unwell, seek medical advice immediately (show the
label where possible).
US Statements: Probable Carcinogen (US). Readily absorbed
through skin. Calif. Prop. 65 carcinogen. Target organ(s):
Heart. Central nervous system.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: Yes
NOTES: This product is or contains a component that is subject
to SARA313 reporting requirements.
UNITED STATES - STATE REGULATORY INFORMATION
OSHA Remarks: OSHA regulated - see CFR title 29 part 1910.1052.
CALIFORNIA PROP - 65
California Prop - 65: This product is or contains chemical(s)
known to the state of California to cause cancer.
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
SUPELCO - 8S61336 www.sigma-aldrich.com Page 5
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2008 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
SUPELCO - 8S61336 www.sigma-aldrich.com Page 6
SIGMA-ALDRICH
Material Safety Data Sheet
Version 3.2
Revision Date 01/11/2008
Print Date 02/18/2008
1. PRODUCT AND COMPANY IDENTIFICATION
Product name : Benzaldehyde
Product Number : 418099
Brand : Aldrich
Company : Sigma-Aldrich
3050 Spruce Street
SAINT LOUIS MO 63103
USA
Telephone : +1 800-325-5832
Fax : +1 800-325-5052
Emergency Phone # : (314) 776-6555
2. COMPOSITION/INFORMATION ON INGREDIENTS
Synonyms : Artificial essential oil of almond
Formula : C7H6O
Molecular Weight : 106.12 g/mol
CAS-No. EC-No. Index-No. Concentration
Benzaldehyde
100-52-7 202-860-4 605-012-00-5 -
3. HAZARDS IDENTIFICATION
Emergency Overview
OSHA Hazards
Combustible Liquid
Target Organ Effect
Harmful by ingestion.
Harmful by skin absorption.
Skin and respiratory sensitizer
Irritant
Target Organs
Central nervous system, Liver, Kidney
HMIS Classification
Health Hazard: 3
Chronic Health Hazard: *
Flammability: 2
Physical hazards: 1
NFPA Rating
Health Hazard: 3
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Fire : 2
Reactivity Hazard: 1
Potential Health Effects
May be harmful if inhaled. May cause respiratory tract irritation.
Inhalation
Harmful if absorbed through skin. May cause skin irritation.
Skin
May cause eye irritation.
Eyes
Harmful if swallowed.
Ingestion
4. FIRST AID MEASURES
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.
If inhaled
If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
5. FIRE-FIGHTING MEASURES
Flammable properties
Flash point 64 掳C (147 掳F) - closed cup
Ignition temperature 190 掳C (374 掳F)
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special protective equipment for fire-fighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
Under fire conditions, material may decompose to form flammable and/or explosive mixtures in air.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation.
Environmental precautions
Do not let product enter drains.
Methods for cleaning up
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for
disposal.
7. HANDLING AND STORAGE
Handling
Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking. Take measures to prevent the build up of electrostatic charge.
Storage
Keep container tightly closed in a dry and well-ventilated place. Store under nitrogen.
Air, light, and moisture sensitive.
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8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Contains no substances with occupational exposure limit values.
Personal protective equipment
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-
purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If
the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and
components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Hand protection
Handle with gloves.
Eye protection
Safety glasses
Skin and body protection
Choose body protection according to the amount and concentration of the dangerous substance at the work
place.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end
of workday.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
Form liquid
Colour colourless
Safety data
pH 5.9 at 20 掳C (68 掳F)
Melting point -26 掳C (-15 掳F)
Boiling point 177 - 179 掳C (351 - 354 掳F)
Flash point 64 掳C (147 掳F) - closed cup
Ignition temperature 190 掳C (374 掳F)
Lower explosion limit 1.4 %(V)
Upper explosion limit 8.5 %(V)
Vapour pressure 5 hPa (4 mmHg) at 45 掳C (113 掳F)
Density 1.050 g/cm3
Water solubility slightly soluble
Partition coefficient: log Pow: 1.5
n-octanol/water
Relative vapour 3.66
density - (Air = 1.0)
10. STABILITY AND REACTIVITY
Storage stability
Stable under recommended storage conditions.
Conditions to avoid
Air Exposure to moisture. Light. Heat.
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Materials to avoid
Strong oxidizing agents, Strong reducing agents, Strong bases, Alkali metals, Aluminium, Iron, phenols, Oxygen
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides
11. TOXICOLOGICAL INFORMATION
Acute toxicity
LD50 Oral - rat - 1,300 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity). Behavioral:Coma.
LD50 Dermal - rabbit - 1,250 mg/kg
Irritation and corrosion
Skin - rabbit - Skin irritation - 24 h
Eyes - rabbit - Mild eye irritation
Sensitisation
May cause allergic respiratory and skin reactions
Chronic exposure
This product is or contains a component that is not classifiable as to its carcinogenicity based on its IARC, ACGIH,
NTP, or EPA classification.
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as
a carcinogen or potential carcinogen by ACGIH.
NTP: No component of this product present at levels greater than or equal to 0.1% is identified as
a known or anticipated carcinogen by NTP.
OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as
a carcinogen or potential carcinogen by OSHA.
Laboratory experiments have shown mutagenic effects.
Signs and Symptoms of Exposure
Central nervous system depression, Prolonged or repeated exposure to skin causes defatting and dermatitis.
Potential Health Effects
May be harmful if inhaled. May cause respiratory tract irritation.
Inhalation
Harmful if absorbed through skin. May cause skin irritation.
Skin
May cause eye irritation.
Eyes
Harmful if swallowed.
Ingestion
Central nervous system, Liver, Kidney,
Target Organs
12. ECOLOGICAL INFORMATION
Elimination information (persistence and degradability)
Biodegradability Biotic/Aerobic
Ecotoxicity effects
Toxicity to fish LC50 - Lepomis macrochirus - 1.07 mg/l - 96 h
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mortality LOEC - Pimephales promelas (fathead minnow) - 0.45 mg/l - 7 d
mortality NOEC - Pimephales promelas (fathead minnow) - 0.22 mg/l - 7 d
LC50 - Leuciscus idus (Golden orfe) - 62 mg/l - 48 h
Toxicity to daphnia EC50 - Daphnia magna (Water flea) - 50 mg/l - 24 h
and other aquatic
invertebrates.
Further information on ecology
no data available
13. DISPOSAL CONSIDERATIONS
Product
This combustible material may be burned in a chemical incinerator equipped with an afterburner and scrubber.
Observe all federal, state, and local environmental regulations. Contact a licensed professional waste disposal
service to dispose of this material.
Contaminated packaging
Dispose of as unused product.
14. TRANSPORT INFORMATION
DOT (US)
UN-Number: 1990 Class: 9 Packing group: III
Proper shipping name: Benzaldehyde
IMDG
UN-Number: 1990 Class: 9 Packing group: III EMS-No: F-A, S-A
Proper shipping name: BENZALDEHYDE
Marine pollutant: No
IATA
UN-Number: 1990 Class: 9 Packing group: III
Proper shipping name: Benzaldehyde
15. REGULATORY INFORMATION
OSHA Hazards
Combustible Liquid, Target Organ Effect, Harmful by ingestion., Harmful by skin absorption., Skin and respiratory
sensitizer, Irritant
TSCA Status
On TSCA Inventory
DSL Status
All components of this product are on the Canadian DSL list.
SARA 302 Components
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the
threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards
Fire Hazard, Acute Health Hazard, Chronic Health Hazard
Massachusetts Right To Know Components
CAS-No. Revision Date
Benzaldehyde 100-52-7 1989-12-01
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Pennsylvania Right To Know Components
CAS-No. Revision Date
Benzaldehyde 100-52-7 1989-12-01
New Jersey Right To Know Components
CAS-No. Revision Date
Benzaldehyde 100-52-7 1989-12-01
California Prop. 65 Components
This product does not contain any chemicals known to State of California to cause cancer, birth, or any other
reproductive defects.
16. OTHER INFORMATION
Further information
Copyright 2008 Sigma-Aldrich Co. License granted to make unlimited paper copies for internal use only.
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a
guide. The information in this document is based on the present state of our knowledge and is applicable to the
product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the
product. Sigma-Aldrich Co., shall not be held liable for any damage resulting from handling or from contact with
the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich Corporation
Aldrich - 418099 Page 6 of 6
www.sigma-aldrich.com
SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 02/18/2008
Date Updated: 06/29/2007
Version 1.15
Section 1 - Product and Company Information
Product Name ETHANOL, DENATURED, REAGENT GRADE
Product Number 362808
Brand ALDRICH
Company Sigma-Aldrich
Address 3050 Spruce Street
SAINT LOUIS MO 63103 US
Technical Phone: 800-325-5832
Fax: 800-325-5052
Emergency Phone: 314-776-6555
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
ETHANOL, DENATURED 5% MEOH, 5% IPA 64-17-5 Yes
Ingredient Name CAS # Percent SARA 313
ETHYL ALCOHOL, NON-DENATURED, 200 64-17-5 90 No
PROOF
METHANOL 67-56-1 5 Yes
2-PROPANOL 67-63-0 5 Yes
Formula C2H6O
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Flammable (USA) Highly Flammable (EU). Toxic (USA) Harmful (EU).
Highly flammable. Harmful by inhalation, in contact with skin and
if swallowed. Irritating to eyes and respiratory system. Harmful:
possible risk of irreversible effects through inhalation, in
contact with skin, and if swallowed.
Target organ(s): Eyes. Nerves.
HMIS RATING
HEALTH: 2*
FLAMMABILITY: 3
REACTIVITY: 1
NFPA RATING
HEALTH: 2
FLAMMABILITY: 3
REACTIVITY: 1
*additional chronic hazards present.
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
Section 5 - Fire Fighting Measures
FLAMMABLE HAZARDS
Flammable Hazards: Yes
EXPLOSION HAZARDS
Vapor may travel considerable distance to source of ignition and
flash back. Container explosion may occur under fire conditions.
Forms explosive mixtures in air.
FLASH POINT
48 藲F 9 藲C Method: closed cup
EXPLOSION LIMITS
Lower: 3.3 % Upper: 24.5 %
AUTOIGNITION TEMP
362 藲C
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: For small (incipient) fires, use media such as
"alcohol" foam, dry chemical, or carbon dioxide. For large
fires, apply water from as far as possible. Use very large
quantities (flooding) of water applied as a mist or spray; solid
streams of water may be ineffective. Cool all affected
containers with flooding quantities of water.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Flammable liquid.
Specific Method(s) of Fire Fighting: Use water spray to cool
fire-exposed containers.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
ALDRICH - 362808 www.sigma-aldrich.com Page 2
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe vapor. Avoid contact with eyes,
skin, and clothing. Avoid prolonged or repeated exposure. Do not
use if skin is cut or scratched. Wash thoroughly after handling.
STORAGE
Suitable: Keep container closed. Keep away from heat, sparks,
and open flame.
SPECIAL REQUIREMENTS
Handle and store under inert gas. Moisture sensitive.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Use only in a
chemical fume hood.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Use respirators and components tested and approved
under appropriate government standards such as NIOSH (US) or CEN
(EU). Where risk assessment shows air-purifying respirators are
appropriate use a full-face respirator with multi-purpose
combination (US) or type ABEK (EN 14387) respirator cartridges as
a backup to engineering controls. If the respirator is the sole
means of protection, use a full-face supplied air respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Remove and wash contaminated
clothing promptly.
Section 9 - Physical/Chemical Properties
Appearance Physical State: Liquid
Property Value At Temperature or Pressure
Molecular Weight 46.07 AMU
pH N/A
BP/BP Range 78 藲C 760 mmHg
MP/MP Range - 130.0 藲C
Freezing Point N/A
Vapor Pressure 44.6 mmHg 20 藲C
Saturated Vapor Conc. N/A
SG/Density 0.785 g/cm3
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
ALDRICH - 362808 www.sigma-aldrich.com Page 3
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point 48 藲F 9 藲C Method: closed cup
Explosion Limits Lower: 3.3 %
Upper: 24.5 %
Flammability N/A
Autoignition Temp 362 藲C
Refractive Index 1.36
Optical Rotation N/A
Miscellaneous Data N/A
Solubility N/A
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: Moisture.
Materials to Avoid: Oxidizing agents, Peroxides, Acids, Acid
chlorides, Acid anhydrides, Alkali metals, Ammonia.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: Harmful if absorbed through skin.
Eye Contact: May cause eye irritation.
Inhalation: Harmful if inhaled. Material may be irritating to
mucous membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.
TARGET ORGAN(S) OR SYSTEM(S)
Nerves. Eyes. Liver. Kidneys. G.I. System. Cardiovascular
system. Heart.
SIGNS AND SYMPTOMS OF EXPOSURE
May cause convulsions. Narcotic effect. Nausea, dizziness, and
headache. Gastrointestinal disturbances. To the best of our
knowledge, the chemical, physical, and toxicological properties
have not been thoroughly investigated. Can cause CNS depression.
Exposure can cause:
CHRONIC EXPOSURE - CARCINOGEN
Result: This product is or contains a component that is not
classifiable as to its carcinogenicity based on its IARC, ACGIH,
NTP, or EPA classification.
Section 12 - Ecological Information
No data available.
ALDRICH - 362808 www.sigma-aldrich.com Page 4
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Burn in a chemical incinerator equipped with an
afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and
local environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: Ethanol [or] Ethyl alcohol [or]
Ethanol solutions [or] Ethyl alcohol solutions
UN#: 1170
Class: 3
Packing Group: Packing Group II
Hazard Label: Flammable liquid
PIH: Not PIH
IATA
Proper Shipping Name: Ethanol solution
IATA UN Number: 1170
Hazard Class: 3
Packing Group: II
Section 15 - Regulatory Information
EU ADDITIONAL CLASSIFICATION
Symbol of Danger: F-Xn
Indication of Danger: Highly Flammable. Harmful.
R: 11-20/21/22-68/20/21/22
Risk Statements: Highly flammable. Harmful by inhalation, in
contact with skin and if swallowed. Harmful: possible risk of
irreversible effects through inhalation, in contact with skin,
and if swallowed.
S: 16-36/37
Safety Statements: Keep away from sources of ignition - no
smoking. Wear suitable protective clothing and gloves.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Flammable (USA) Highly Flammable (EU).
Toxic (USA) Harmful (EU).
Risk Statements: Highly flammable. Irritating to eyes and
respiratory system. Harmful by inhalation, in contact with skin
and if swallowed. Harmful: possible risk of irreversible effects
through inhalation, in contact with skin, and if swallowed.
Safety Statements: Keep away from sources of ignition - no
smoking. Keep container in a well-ventilated place. In case of
contact with eyes, rinse immediately with plenty of water and
seek medical advice. Do not empty into drains. Take
precautionary measures against static discharges.
US Statements: Target organ(s): Eyes. Nerves.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: Yes
NOTES: This product is or contains a component that is subject
to SARA313 reporting requirements.
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
ALDRICH - 362808 www.sigma-aldrich.com Page 5
contains all the information required by the CPR.
DSL: No
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2008 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
ALDRICH - 362808 www.sigma-aldrich.com Page 6
SIGMA-ALDRICH
Material Safety Data Sheet
Version 3.0
Revision Date 05/15/2007
Print Date 02/18/2008
1. PRODUCT AND COMPANY IDENTIFICATION
Product name : Distilled water
Product Number : 07-6061
Brand : Katayama OEM Partner
Company : Sigma-Aldrich
3050 Spruce Street
SAINT LOUIS MO 63103
USA
Telephone : +1 800-325-5832
Fax : +1 800-325-5052
Emergency Phone # : (314) 776-6555
2. COMPOSITION/INFORMATION ON INGREDIENTS
Formula : H2O
Molecular Weight : 18.02 g/mol
CAS-No. EC-No. Index-No. Concentration [%]
Water
7732-18-5 231-791-2 - -
3. HAZARDS IDENTIFICATION
Emergency Overview
OSHA Hazards
No OSHA Hazards
HMIS Classification
Health Hazard: 0
Flammability: 0
Physical hazards: 0
NFPA Rating
Health Hazard: 0
Fire : 0
Reactivity Hazard: 0
Potential Health Effects
May cause respiratory tract irritation.
Inhalation
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4. FIRST AID MEASURES
If inhaled
If not breathing give artificial respiration
5. FIRE-FIGHTING MEASURES
Flammable properties
Flash point not applicable
Ignition temperature not applicable
Suitable extinguishing media
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Further information
The product itself does not burn.
6. ACCIDENTAL RELEASE MEASURES
Methods for cleaning up
Wipe up with absorbent material (e.g. cloth, fleece).
7. HANDLING AND STORAGE
Storage
No special storage conditions required.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Contains no substances with occupational exposure limit values.
Personal protective equipment
Respiratory protection
No special protective equipment required.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
Form liquid
Colour colourless
Safety data
pH 6.0 - 8.0 at 25 掳C (77 掳F)
Melting point 0.0 掳C (32.0 掳F)
Boiling point 100.0 掳C (212.0 掳F)
Flash point not applicable
Ignition temperature not applicable
Lower explosion limit not applicable
Upper explosion limit not applicable
Density 1.00 g/cm3
Water solubility completely miscible
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10. STABILITY AND REACTIVITY
Storage stability
Stable under recommended storage conditions.
11. TOXICOLOGICAL INFORMATION
Acute toxicity
LD50 Oral - rat - > 90,000 mg/kg
Irritation and corrosion
no data available
Sensitization
no data available
Chronic exposure
no data available
Potential Health Effects
May cause respiratory tract irritation.
Inhalation
12. ECOLOGICAL INFORMATION
Elimination information (persistence and degradability)
not applicable
Ecotoxicity effects
no data available
Further information on ecology
no data available
13. DISPOSAL CONSIDERATIONS
Product
Taking into account local regulations the product may be disposed of as waste water after neutralisation.
14. TRANSPORT INFORMATION
DOT (US)
Not dangerous goods
IMDG
Not dangerous goods
IATA
Not dangerous goods
15. REGULATORY INFORMATION
OSHA Hazards
No OSHA Hazards
TSCA Status
On TSCA Inventory
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DSL Status
All components of this product are on the Canadian DSL list.
SARA 302 Components
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the
threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards
No SARA Hazards
Massachusetts Right To Know Components
No Components Listed
Pennsylvania Right To Know Components
CAS-No. Revision Date
Water 7732-18-5
New Jersey Right To Know Components
CAS-No. Revision Date
Water 7732-18-5
California Prop. 65 Components
This product does not contain any chemicals known to State of California to cause cancer, birth, or any other
reproductive defects.
16. OTHER INFORMATION
Further information
Copyright 2007 Sigma-Aldrich Co. License granted to make unlimited paper copies for internal use only., The above
information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our knowledge and is applicable to the product with
regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-
Aldrich Co., shall not be held liable for any damage resulting from handling or from contact with the above product.
See reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich Corporation
Katayama OEM Partner - 07-6061 Page 4 of 4
www.sigma-aldrich.com
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