MSDS Number: 6092FR 5/15/02 2:08 PM
VERTREL庐 MCA
6092FR Revised 15-Sept-2001
CHEMICAL PRODUCT/COMPANY IDENTIFICATION
Material Identification
Formula : CF3CHFCHFCF2CF3,CC1H=CC1H(TRANS)
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont
Fluoroproducts
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information : 1-800-441-7515 (outside the U.S.
302-774-1000)
Transport Emergency : CHEMTREC 1-800-424-9300(outside U.S.
703-527-3887)
Medical Emergency : 1-800-441-3637 (outside the U.S.
302-774-1000)
COMPOSITION/INFORMATION ON INGREDIENTS
Components CAS Number %
1,1,1,2,2,3,4,5,5,5-decafluoropentane (HFC-43-10mee) 138495-42-8 59.0-65.0
TRANS, 1,2-DICHLOROETHYLENE (t-DCE) 156-60-5 35.0-41.0
HAZARDS IDENTIFICATION
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Potential Health Effects
Gross overexposure by inhalation to HFC-43-10mee may cause
suffocation if air is displaced by vapors and central
nervous system stimulation with increased activity or
sleeplessness, tremors or convulsions. These effects may be
followed by central nervous system depression with
dizziness, confusion, incoordination, drowsiness or
unconsciousness. Based on data from other fluorocarbons,
gross overexposure to HFC-43-10mee may cause irregular heart
beat with a strange sensation in the chest, "heart thumping"
apprehension, lightheadedness, feeling of fainting,
dizziness, weakness, sometimes progressing to loss of
consciousness and death. Intentional misuse or deliberate
inhalation may cause death without warning. Vapor reduces
oxygen available for breathing and is heavier than air.
Immediate effects of overexposure to HFC-43-10mee by skin
contact may include slight irritation with itching, redness
or swelling. Repeated and/or prolonged exposure may cause
defatting of the skin with itching, redness or rash. Based
on animal data, significant skin permeation, and systemic
toxicity after skin contact, appears unlikely. Immediate
effects of overexposure to HFC-43-10mee by eye contact may
include eye irritation with tearing, pain or blurred vision.
The major ingestion hazard of HFC-43-10mee is aspiration
(liquid entering the lungs during ingestion or vomiting)
which may result in "chemical pneumonia." Symptoms include
coughing, gasping, choking, shortness of breath, bluish
discoloration of the skin, rapid breathing and heart rate,
and fever. Pulmonary edema or bleeding, drowsiness,
confusion, coma and seizures may occur in more serious
cases. Symptoms may develop immediately or as late as 24
hours after exposure, depending on how much chemical entered
the lungs. Increased susceptibility to the effects of
HFC-43-10mee may be observed in persons with pre-existing
disease of the central nervous system or the cardiovascular
system.
Inhalation of t-DCE may cause central nervous system
depression with dizziness, confusion, incoordination,
drowsiness or unconsciousness; or tremors, nausea, vomiting,
weakness, and abdominal cramps. Other effects may include
irregular heart beat with a strange sensation in the chest,
"heart thumping", apprehension, lightheadedness, feeling of
fainting, dizziness, or weakness. Skin contact with t-DCE
may cause severe irritation with burning, redness, swelling,
pain or rash. Eye contact with t-DCE may cause severe eye
irritation with tearing, pain or blurred vision. Ingestion
of t-DCE may cause pulmonary edema (body fluid in the lungs)
with cough, wheezing, abnormal lung sounds, possibly
progressing to severe shortness of breath and bluish
discoloration of the skin: symptoms may be delayed.
Ingestion may also cause pathological changes in the liver,
central nervous system depression with dizziness, confusion,
incoordination, drowsiness or unconsciousness, and
structural (pathological) changes in heart muscle tissue.
Carcinogenicity Information
None of the components present in this material at concentrations
equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH
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as a carcinogen.
FIRST AID MEASURES
First Aid
INHALATION
If inhaled, immediately remove to fresh air. Keep person calm.
If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. Call a physician.
SKIN CONTACT
Flush skin with water after contact. Wash contaminated clothing
before reuse.
EYE CONTACT
In case of contact, immediately flush eyes with plenty of water
for at least 15 minutes. Call a physician.
INGESTION
Material poses an aspiration hazard. If swallowed, do not induce
vomiting. Immediately give 2 glasses of water. Never give
anything by mouth to an unconscious person. Call a physician.
If vomiting occurs naturally, have victim lean forward to reduce
the risk of aspiration.
Notes to Physicians
THIS MATERIAL MAY MAKE THE HEART MORE SUSCEPTIBLE TO ARRHYTHMIAS.
Catecholamines such as adrenaline, and other compounds having
similar effects, should be reserved for emergencies and then used
only with special caution.
FIRE FIGHTING MEASURES
Flammable Properties
Flammable limits in Air, % by Volume
LEL : None.
UEL : None.
Flash Point : None
Method : Pensky-Martens Closed Cup (ASTM D 93)
Flash Point : None
Method : Tag Open Cup (ASTM D 1310)
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AUTOIGNITION TEMPERATURE:
Has not yet been determined for "Vertrel" MCA.
Fire and Explosion Hazards:
Use water spray or fog to cool containers. Drums may
rupture under fire conditions. Decomposition may occur.
Extinguishing Media
Use media appropriate for surrounding material.
Fire Fighting Instructions
Self-contained breathing apparatus (SCBA) is required if
drums rupture and contents are spilled under fire
conditions.
ACCIDENTAL RELEASE MEASURES
Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Initial Containment
Dike spill. Prevent material from entering sewers, waterways, or
low areas.
&bull Spill Clean Up
Immediately evacuate the area and provide maximum
ventilation, especially in low places where heavy vapors
might collect. Unprotected personnel should move upwind of
spill. Only personnel equipped with proper respiratory and
skin/eye protection should be permitted in area. Soak up
with sawdust, sand, oil dry or other absorbent material.
After all visible traces, including ignitable vapors, have
been removed, thoroughly wet vacuum the area. Do not flush
to sewer. If area of spill is porous, remove as much
contaminated earth and gravel, etc. as necessary and place
in closed containers for disposal.
HANDLING AND STORAGE
&bull Handling (Personnel)
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Avoid breathing vapors or mist. Avoid contact with eyes, skin, or
clothing. Wash thoroughly after handling.
The use of gloves is recommended when working with the
material containers. Material should not be dispensed from
its container by pouring, except for small sample containers
where fume hoods or where other ventilation is used to
manage the exposure limits. The use of a drum pump is
recommended for dispensing from shipping containers.
Storage
Store in a clean, dry area. Do not allow stored product to
exceed 52 C (125 F) to prevent leakage or potential rupture
of container from pressure and expansion. Protect from
freezing temperatures. If solvent is stored below -10 C
(14 F), mix prior to use.
EXPOSURE CONTROLS/PERSONAL PROTECTION
Engineering Controls
Use only with adequate ventilation. Keep container tightly closed.
Vapors are heavier than air posing a hazard of asphyxia if
they are trapped in enclosed or low places.
Personal Protective Equipment
EYE/FACE PROTECTION
Wear safety glasses or coverall chemical splash goggles.
RESPIRATORS
Where there is potential for airborne exposures in excess of
applicable limits, wear NIOSH approved respiratory
protection.
PROTECTIVE CLOTHING
Where there is potential for skin contact have available and
wear as appropriate impervious gloves, apron, pants, and
jacket.
Protective gloves and chemical splash goggles should be used
when handling liquid.
Exposure Guidelines
Applicable Exposure Limits
1,1,1,2,2,3,4,5,5,5-DECAFLUOROPENTANE (HFC-43-10mee)
PEL (OSHA) : None Established
TLV (ACGIH) : None Established
AEL * (DuPont) : 200 ppm, 8 & 12 Hr. TWA
400 ppm, Ceiling
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TRANS, 1,2-DICHLOROETHYLENE (t-DCE)
PEL (OSHA) : 200 ppm, 790 mg/m3, 8 Hr. TWA
TLV (ACGIH) : 200 ppm, 8 Hr. TWA
AEL * (DuPont) : 200 ppm, 8 & 12 Hr. TWA
* AEL is DuPont's Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
PHYSICAL AND CHEMICAL PROPERTIES
Physical Data
Boiling Point : 39 C (102 F)
Vapor Pressure : 464 mm Hg @ 25 C (77 F)
Vapor Density : 5.4 (Air=1.0) Heavier than air.
Form : Liquid
Color : Colorless
Density : 1.41 g/cm3 @ 25 C (77 F)
11.8 lb/gal
STABILITY AND REACTIVITY
Chemical Stability
Stable at normal temperatures and storage conditions.
Incompatibility with Other Materials
Incompatible with alkali or alkaline earth metals - powdered
Al, Zn, Be, Na, Mg, etc.
Incompatible with strong bases such as NaOH, KOH, etc.
Decomposition
Decomposes with heat. High temperatures (open flames,
glowing metal surfaces, etc.) can decompose HFC-43-10mee
forming hydrofluoric acids and possibly carbonyl halides.
HFC-43-10mee is incompatible with strong bases and can react
to form salts of hydrofluoric acid and unsaturated compounds
of unknown toxicity.
1,2-Trans DCE is unstable at high temperatures and will form
hydrochloric acid and unsaturates as well as break down or
react in the presence of caustic to form salts of
hydrochloric acid.
Polymerization
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Polymerization will not occur.
TOXICOLOGICAL INFORMATION
&bull Animal Data
HFC-43-10mee
Oral LD50: > 5,000 mg/kg in rats
Dermal ALD: > 5,000 mg/kg in rabbits
Inhalation, 4 hour LC50: 11,100 ppm in rats
t-DCE
Oral LD50: 1275 mg/kg in rats
Dermal LD50: > 5000 mg/kg in rabbits
Inhalation LC50, 4 hr: 24,100 ppm in rats
Animal testing indicates that HFC-43-10mee is a slight skin
irritant and a mild eye irritant, but is not a skin
sensitizer. Single exposure to 5,000 ppm HFC-43-10mee by
inhalation caused tremors. A different single exposure
study by inhalation in rats caused incoordination,
hyperactivity and prostration; pathological examination of
rats from this study revealed kidney and lung changes, and
external hair loss. Repeated exposures to 1,900 - 3,500 ppm
caused tremors or convulsions, behavioral effects, and
altered clinical chemistry. These effects were temporary.
In a different repeated exposure test the
No-Observed-Adverse-Effect-Level (NOAEL) for convulsions was
1000 ppm. Results indicate convulsions is an acute effect
of HFC-43-10mee. The 90-day No-Observed-Adverse-Effect-Level
(NOAEL) is 500 ppm. In animal testing HFC-43-10mee produced
developmental effects only at exposure levels producing
other toxic effects in the adult animal. No animal data are
available to define the carcinogenic or reproductive hazards
of HFC-43-10mee. Tests have shown that HFC-43-10mee does
not cause genetic damage in bacterial or mammalian cell
cultures. It has not produced genetic damage in tests on
animals.
t-DCE is a severe eye irritant, and a moderate to severe
skin irritant. Single and repeated exposure to t-DCE by
ingestion caused increased kidney weight, histopathological
changes of the lungs, liver effects, decreased motor
activity, pulmonary edema, cardiovascular system changes,
and mortality. Single and repeated exposure to t-DCE by
inhalation caused pathological changes of the liver and
lungs, inactivity or anaesthesia, altered white blood cell
count, cardiovascular system changes and weak cardiac
sensitization, a potentially fatal disturbance of the heart
rhythm caused by a heightened sensitivity to the action of
epinephrine. Long-term exposure caused altered liver and
lung function. A more recent inhalation study (Dec. 1998)
conducted with well-characterized t-DCE containing > 99.4%
t-DCE, produced no adverse, compound-related effects. The
NOEL was 4000 ppm. Exposure of pregnant rats shows maternal
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toxicity at 2000, 6000 and 12,000 ppm. Developmental
toxicity was seen only at 12,000 ppm. Tests have shown that
t-DCE does not cause genetic damage in bacterial or
mammalian cell cultures. No animal data are available to
define the carcinogenic or reproductive hazards of t-DCE.
ECOLOGICAL INFORMATION
Ecotoxicological Information
Aquatic Toxicity:
HFC-43-10mee
96 hour LC50, fathead minnows: 27.2 mg/L
96 hour LC50, rainbow trout: 13.9 mg/L
48 hour LC50, Daphnia magna: 11.7 mg/L
t-DCE
96 hour LC50, bluegill sunfish: 1350 mg/L
48 hour LC50, Daphnia magna: 220 mg/L
DISPOSAL CONSIDERATIONS
Waste Disposal
Treatment, storage, transportation, and disposal must be in
accordance with applicable Federal, State/Provincial, and Local
regulations.
TRANSPORTATION INFORMATION
&bull Shipping Information
DOT/IMO/IATA - Not regulated in containers with less than
2600 lbs. If greater than 2600 lbs. use:
Proper Shipping Name: Environmentally Hazardous Substance,
Liquid, N.O.S. (Trans-1,2-Dichloroethylene)
Hazard Class :9
UN Number : 3082
Packing Group : III
Reportable Quantity : 1000 lbs. (Trans-1,2-Dichloroethylene)
2600 lbs. ("Vertrel" MCA)
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REGULATORY INFORMATION
U.S. Federal Regulations
All Components Are Listed on the TSCA Public Inventory
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute : Yes
Chronic : No
Fire : No
Reactivity : No
Pressure : No
1,1,1,2,2,3,4,5,5,5-DECAFLUOROPENTANE (CAS# 138495-42-8) is
controlled by TSCA Section 5, Significant New Use Rule
(SNUR; 40 CFR 721.5645) The approved uses are: precision and
general cleaning, carrier fluid, displacement drying,
printed circuit board cleaning, particulate removal and film
cleaning, process medium, heat transfer fluid (dielectric
and non-dielectric), and test fluid. Processors and users
of this substance must also comply with the applicable
general SNUR requirements set forth in 40 CFR 721 subpart A
and the applicable record keeping requirements set forth at
40 CFR 721.125.
LISTS:
SARA Extremely Hazardous Substance -No
CERCLA Hazardous Substance -Yes*
*1,2 Dichloroethylene Component Only
OTHER INFORMATION
NFPA, NPCA-HMIS
NPCA-HMIS Rating
Health :1
Flammability :0
Reactivity :1
Personal Protection Rating to be supplied by user, depending on use and conditions.
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VERTREL庐 is a registered trademark of DuPont.
The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Information in this format is provided as a service to our
customers and is intended only for their use. Others may use it
at their own discretion and risk.
The MSDS format adheres to U.S. standards and regulatory
requirements and may not meet regulatory requirements in other
locations.
This information is based upon technical information
believed to be reliable. It is subject to revision as additional
knowledge and experience are gained. Please return to this
website for the most current version.
Responsibility for MSDS:
MSDS Coordinator
DuPont Fluoroproducts
Wilmington, DE 19898
(800) 441-7515
End of MSDS
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