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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 09/02/2003 Reviewed on 09/02/2003
1 IDENTIFICATION OF SUBSTANCE
Trade name: 5(6)-FAM
Product Number: 3430A
Application of the substance / the preparation: Laboratory chemicals
Manufacturer/Supplier:
Promega Biosciences
277 Granada Drive
San Luis Obispo, CA 93401
Information department: Promega Corporation, Environmental Health and Safety Department
Emergency information: CHEMTREC 1-800-424-9300
2 COMPOSITION/DATA ON COMPONENTS
Chemical characterization
Description: Mixture of the substances listed below with nonhazardous additions.
Dangerous Components:
72088-94-9 5-(and-6)-carboxyfluorescein (5(6)-FAM) *mixed isomers* >95.0%
Additional information:
For applicable regulatory lists, carcogenicity information and wording of Risk phrases, please refer to section 15.
3 HAZARDS IDENTIFICATION
Hazard description (European Union) The toxicological effect of this product has not been investigated
Information pertaining to particular dangers for man and environment
This product does not have to be labelled in accordance with the calculation procedure of the "General
Classification guideline for preparations of the EU" in the latest valid version.
Classification system:
The classification above was made according European Community Directives including the latest editions of
international substance lists. The classification below is made according to 29CFR1910.1200 and both are
expanded upon by technical literature/supplier company information.
National Fire Protection Association (NFPA ratings scale 0-4)
Health = 0
Fire = 0
Reactivity = 0
Hazardous Material Identification System (HMIS Ratings scale 0-4)
Health = 0
Flammability = 0
Reactivity = 0
OSHA Hazard Overview (Criteria according to 29CFR1910.1200):
The toxicological effect of this product has not been investigated.
Potentially Harmful
Primary route(s) of entry:
Oral
Dermal
(Contd. on page 2)
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 09/02/2003 Reviewed on 09/02/2003
Trade name: 5(6)-FAM
(Contd. of page 1)
Target Organ(s): Not applicable or unknown
4 FIRST AID MEASURES
General information No special measures required.
After inhalation: Supply fresh air; consult doctor in case of complaints.
After skin contact: Generally the product does not irritate the skin.
After eye contact: Rinse opened eye for several minutes under running water.
After swallowing: If symptoms persist consult doctor.
5 FIRE FIGHTING MEASURES
Suitable extinguishing agents:
Dry chemical(extinguishing powder), CO2, water or regular foam. Fight larger fires with water spray or alcohol
resistant foam.
Protective equipment: No special measures required.
6 ACCIDENTAL RELEASE MEASURES
Person-related safety precautions: Not required.
Measures for environmental protection: Do not allow to enter sewers/surface or ground water.
Measures for cleaning/collecting: Dispose contaminated material as waste according to item 13.
Additional information: No dangerous substances are released.
7 HANDLING AND STORAGE
Handling
Information for safe handling: Store in cool, dry place in tightly closed receptacles.
Information about protection against explosions and fires: No special measures required.
Storage
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: Protect from heat and direct sunlight.
8 EXPOSURE CONTROLS AND PERSONAL PROTECTION
Components with Occupational Exposure Limits:
The product does not contain any relevant quantities of materials with critical values that require monitoring at
the workplace.
Additional information: The lists that were valid during the creation were used as basis.
Personal protective equipment
General protective and hygienic measures
The usual precautionary measures for handling chemicals should be followed.
Breathing equipment: Not required.
Protection of hands:
Protective gloves.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
Material of gloves:
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer.
(Contd. on page 3)
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 09/02/2003 Reviewed on 09/02/2003
Trade name: 5(6)-FAM
(Contd. of page 2)
Eye protection: Not required.
9 PHYSICAL AND CHEMICAL PROPERTIES
General Information
Solid
Form:
Variable
Color:
Odorless
Odor:
Change in condition
Melting point/Melting range: Undetermined
Boiling point/Boiling range: Undetermined
Not applicable
Flash point:
Product is not selfigniting.
Auto igniting:
Product does not present an explosion hazard.
Danger of explosion:
Not determined
Density:
Solubility in / Miscibility with
Insoluble
Water:
Solvent content
<2.0 %
Organic solvents:
10 STABILITY AND REACTIVITY
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Dangerous reactions: No dangerous reactions known
Dangerous products of decomposition: No dangerous decomposition products known
11 TOXICOLOGICAL INFORMATION
Acute toxicity:
Primary irritant effect
on the skin: No irritating effect.
on the eye: Irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information:
The product is not subject to classification according to the calculation method of the General EU Classification
Guidelines for Preparations as issued in the latest version:
When used and handled according to specifications, the product does not have any harmful effects according to
our experience and the information provided to us.
12 ECOLOGICAL INFORMATION
General notes:
Water hazard class 1 (Self-assessment): slightly hazardous for water.
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 09/02/2003 Reviewed on 09/02/2003
Trade name: 5(6)-FAM
(Contd. of page 3)
13 DISPOSAL CONSIDERATION
Product
Recommendation:
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings
Recommendation: Disposal must be made according to official regulations.
14 TRANSPORT INFORMATION
Contact Promega Safety Department for additional transportation information
DOT regulations: Not regulated
-
Hazard class:
Land transport ADR/RID (cross-border)
ADR/RID class: -
Maritime transport IMDG:
-
IMDG Class:
Marine pollutant: No
Air transport ICAO-TI and IATA-DGR:
ICAO/IATA Class: -
15 REGULATIONS
SARA (Superfund Amendment and Reauthorization Act):
Section 302/304(355.30/355.40-Extremely Hazardous Substances):
None of the ingredients is listed.
Section 313 (40CFR372.65-Specific Toxic Chemicals listing):
None of the ingredients is listed.
TSCA (Toxic Substance Control Act):
None of the ingredients is listed.
Proposition 65
Chemicals known to cause cancer:
None of the ingredients is listed.
Chemicals known to cause reproductive toxicity:
None of the ingredients is listed.
Cancerogenity categories
EPA (Environmental Protection Agency):
None of the ingredients is listed.
IARC (International Agency for Research on Cancer):
None of the ingredients is listed.
NTP (National Toxicology Program):
None of the ingredients is listed.
TLV (Threshold Limit Value established by ACGIH):
None of the ingredients is listed.
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 09/02/2003 Reviewed on 09/02/2003
Trade name: 5(6)-FAM
(Contd. of page 4)
MAK (German Maximum Workplace Concentration):
None of the ingredients is listed.
NIOSH-Ca (National Institute for Occupational Safety and Health):
None of the ingredients is listed.
OSHA-Ca (Occupational Safety & Health Administration):
None of the ingredients is listed.
Markings:
Observe the general safety regulations when handling chemicals
The product is not subject to identification regulations under EU Directives and the Ordinance on Hazardous
Materials (GefStoffV).
Safety phrases:
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
This material and its container must be disposed of in a safe way.
Wear suitable protective clothing.
If swallowed, seek medical advice immediately and show this container or label.
National regulations
Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.
16 OTHER INFORMATION
This information is based on our present knowledge. However, this shall not constitute a guarantee for any
specific product features and shall not establish a legally valid contractual relationship.
Department issuing MSDS:
Promega Corporation
Environmental Health and Safety Department
2800 Woods Hollow Road
Madison, WI
Ph:(608)274-4330
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