06/23/2008 Kit components
Product ProFluor® Tyrosine Phosphatase Assay, 4 Plate
Product code V1280
Substance number Description Amount Symbols
V306 Stabilizer Reagent 1 -
V309 Protease Reagent 1 Xi
V325 Control AMC Substrate 1 -
V345 PTPase R110 Substrate 1 -
V343 Sodium Vanadate, 100mM 1 -
V334 5X Reaction Buffer B 1 -
V346 5X Termination Buffer C 1 -
Page 1/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
* 1 Identification of substance
Trade name: Stabilizer Reagent
Article number: V306
Application of the substance / the preparation Laboratory chemicals
Manufacturer/Supplier:
Promega Corporation
2800 Woods Hollow Road
Madison, WI 53711
U.S.A.
1-800-356-9526 or (608)-274-4330
MSDS author: Regulatory.Affairs@promega.com
Emergency information:
CHEMTREC 1-800-424-9300
for call originating outside the United States dial 001-703-527-3887
2 Composition/Data on components
Chemical characterization
Description: Mixture of the substances listed below with nonhazardous additions.
Dangerous components:
64-17-5 ethanol 10-15%
Additional information: For the wording of the listed risk phrases refer to section 15.
3 Hazards identification
Hazard description: Not applicable. Product has been classified as non-hazardous.
Information pertaining to particular dangers for man and environment:
The product does not have to be labelled due to the calculation procedure of international guidelines.
Classification system:
The classification was made according to the latest editions of international substances lists, and is expanded
upon by company and technical literature data.
NFPA ratings (scale 0 - 4)
Health = 0
Fire = 2
Reactivity = 0
HMIS-ratings (scale 0 - 4)
Health = 0
Fire =2
Reactivity = 0
Combustible
OSHA Hazard Overview (Criteria according to 29CFR1910.1200):
Target Organ(s): Not applicable or unknown
USA
(Contd. on page 2)
DR
Page 2/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Stabilizer Reagent
(Contd. of page 1)
4 First aid measures
General information: No special measures required.
After inhalation: Supply fresh air; consult doctor in case of complaints.
After skin contact: Generally the product does not irritate the skin.
After eye contact: Rinse opened eye for several minutes under running water.
After swallowing: If symptoms persist consult doctor.
5 Fire fighting measures
Suitable extinguishing agents:
CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
Protective equipment: No special measures required.
6 Accidental release measures
Person-related safety precautions: Not required.
Measures for environmental protection:
Dilute with plenty of water.
Do not allow to enter sewers/ surface or ground water.
Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Additional information: No dangerous substances are released.
7 Handling and storage
Handling:
Information for safe handling: No special measures required.
Information about protection against explosions and fires: No special measures required.
Storage:
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: None.
8 Exposure controls and personal protection
Components with limit values that require monitoring at the workplace:
64-17-5 ethanol
PEL 1900 mg/m³, 1000 ppm
REL 1900 mg/m³, 1000 ppm
TLV 1880 mg/m³, 1000 ppm
Additional information: The lists that were valid during the creation were used as basis.
Personal protective equipment:
General protective and hygienic measures:
The usual precautionary measures for handling chemicals should be followed.
Breathing equipment: Not required.
Protection of hands:
Protective gloves
(Contd. on page 3)
USA
DR
Page 3/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Stabilizer Reagent
(Contd. of page 2)
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance
of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Eye protection: Goggles recommended during refilling.
* 9 Physical and chemical properties
General Information
Fluid
Form:
Colorless
Color:
Characteristic
Odor:
Change in condition
Melting point/Melting range: Undetermined.
Boiling point/Boiling range: Undetermined.
> 55°C (> 131°F)
Flash point:
425°C (797°F)
Ignition temperature:
Product is not selfigniting.
Auto igniting:
Product does not present an explosion hazard.
Danger of explosion:
Explosion limits:
3.5 Vol %
Lower:
15.0 Vol %
Upper:
Vapor pressure at 20°C (68°F): 59 hPa (44 mm Hg)
Not determined.
Density:
Solubility in / Miscibility with
Fully miscible.
Water:
Solvent content:
12.0 %
Organic solvents:
87.6 %
Water:
12.0 %
VOC content:
10 Stability and reactivity
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Dangerous reactions No dangerous reactions known.
Dangerous products of decomposition: No dangerous decomposition products known.
11 Toxicological information
Acute toxicity:
Primary irritant effect:
on the skin: No irritant effect.
on the eye: Irritating effect.
Sensitization: No sensitizing effects known.
(Contd. on page 4)
USA
DR
Page 4/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Stabilizer Reagent
(Contd. of page 3)
Additional toxicological information:
The product is not subject to classification according to internally approved calculation methods for
preparations:
When used and handled according to specifications, the product does not have any harmful effects according to
our experience and the information provided to us.
12 Ecological information
General notes:
Water hazard class 1 (Self-assessment): slightly hazardous for water
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
13 Disposal considerations
Product:
Recommendation:
Smaller quantities can be disposed of with household waste.
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings:
Recommendation: Disposal must be made according to official regulations.
Recommended cleansing agent: Water, if necessary with cleansing agents.
* 14 Transport information
Contact Promega Safety Department for additional transportation information
Not regulated
DOT regulations:
3
Hazard class:
UN1170
Identification number:
III
Packing group:
Proper shipping name (technical name): ETHANOL SOLUTION
3
Label
Land transport ADR/RID (cross-border):
3 (F1) Flammable liquids
ADR/RID class:
30
Danger code (Kemler):
1170
UN-Number:
III
Packaging group:
3
Label:
1170 ETHANOL SOLUTION (ETHYL ALCOHOL SOLUTION)
Description of goods:
Maritime transport IMDG:
3
IMDG Class:
1170
UN Number:
3
Label
III
Packaging group:
F-E,S-E
EMS Number:
No
Marine pollutant:
ETHANOL SOLUTION (ETHYL ALCOHOL SOLUTION)
Propper shipping name:
(Contd. on page 5)
USA
DR
Page 5/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Stabilizer Reagent
(Contd. of page 4)
Air transport ICAO-TI and IATA-DGR:
3
ICAO/IATA Class:
1170
UN/ID Number:
3
Label
III
Packaging group:
ETHANOL SOLUTION
Propper shipping name:
* 15 Regulations
Sara
Section 355 (extremely hazardous substances):
None of the ingredients are listed.
Section 313 (Specific toxic chemical listings):
None of the ingredients are listed.
TSCA (Toxic Substances Control Act):
7732-18-5 water, distilled, conductivity or of similar purity
64-17-5 ethanol
Proposition 65
Chemicals known to cause cancer:
None of the ingredients are listed.
Chemicals known to cause reproductive toxicity for females:
None of the ingredients are listed.
Chemicals known to cause reproductive toxicity for males:
None of the ingredients are listed.
Chemicals known to cause developmental toxicity:
64-17-5 ethanol
Cancerogenity categories
EPA (Environmental Protection Agency)
None of the ingredients are listed.
IARC (International Agency for Research on Cancer)
None of the ingredients are listed.
NTP (National Toxicology Program)
None of the ingredients are listed.
TLV (Threshold Limit Value established by ACGIH)
64-17-5 ethanol A4
MAK (German Maximum Workplace Concentration)
64-17-5 ethanol 5
NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients are listed.
OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients are listed.
Product related hazard informations:
Observe the general safety regulations when handling chemicals.
(Contd. on page 6)
USA
DR
Page 6/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Stabilizer Reagent
(Contd. of page 5)
The product is not subject to identification regulations according to directives on hazardous materials.
National regulations:
Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.
* 16 Other information
This information is based on our present knowledge. However, this shall not constitute a guarantee for any
specific product features and shall not establish a legally valid contractual relationship.
Department issuing MSDS:
Promega Corporation
Environmental Health and Safety Department
2800 Woods Hollow Road
Madison, WI
Ph:(608)274-4330
* Data compared to the previous version altered.
USA
DR
Page 1/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
* 1 Identification of substance
Trade name: Protease Reagent
Article number: V309
Application of the substance / the preparation Laboratory chemicals
Manufacturer/Supplier:
Promega Corporation
2800 Woods Hollow Road
Madison, WI 53711
U.S.A.
1-800-356-9526 or (608)-274-4330
MSDS author: Regulatory.Affairs@promega.com
Emergency information:
CHEMTREC 1-800-424-9300
for call originating outside the United States dial 001-703-527-3887
2 Composition/Data on components
Chemical characterization
Description: Mixture of the substances listed below with nonhazardous additions.
Dangerous components:
7783-20-2 ammonium sulphate 50-75%
Additional information: For the wording of the listed risk phrases refer to section 15.
3 Hazards identification
Hazard description:
Xi Irritant
Information pertaining to particular dangers for man and environment:
Irritating to eyes, respiratory system and skin.
Classification system:
The classification was made according to the latest editions of international substances lists, and is expanded
upon by company and technical literature data.
NFPA ratings (scale 0 - 4)
Health = 1
Fire = 0
Reactivity = 0
HMIS-ratings (scale 0 - 4)
Health = 1
Fire =0
Reactivity = 0
(Contd. on page 2)
USA
DR
Page 2/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Protease Reagent
(Contd. of page 1)
Irritant
OSHA Hazard Overview (Criteria according to 29CFR1910.1200):
Primary route(s) of entry:
Dermal
Inhalation
Oral
Target Organ(s):
Eye irritant
May cause behavioral changes
4 First aid measures
After inhalation: In case of unconsciousness place patient stably in side position for transportation.
After skin contact: Immediately wash with water and soap and rinse thoroughly.
After eye contact:
Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.
After swallowing: If symptoms persist consult doctor.
5 Fire fighting measures
Suitable extinguishing agents:
CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
* 6 Accidental release measures
Person-related safety precautions: Not required.
Measures for environmental protection:
Dilute with plenty of water.
Do not allow to enter sewers/ surface or ground water.
Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Ensure adequate ventilation.
* 7 Handling and storage
Handling:
Information for safe handling:
Ensure good ventilation/exhaustion at the workplace.
Prevent formation of aerosols.
No special precautions are necessary if used correctly.
Information about protection against explosions and fires: No special measures required.
Storage:
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: Keep receptacle tightly sealed.
USA
(Contd. on page 3)
DR
Page 3/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Protease Reagent
(Contd. of page 2)
* 8 Exposure controls and personal protection
Components with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be monitored at
the workplace.
Additional information: The lists that were valid during the creation were used as basis.
Personal protective equipment:
General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Avoid contact with the eyes and skin.
Breathing equipment:
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use
respiratory protective device that is independent of circulating air.
Protection of hands:
Protective gloves
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance
of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Eye protection: Tightly sealed goggles
9 Physical and chemical properties
General Information
Fluid
Form:
Colorless
Color:
Characteristic
Odor:
Change in condition
Melting point/Melting range: Undetermined.
Boiling point/Boiling range: 100°C (212°F)
Not applicable.
Flash point:
Product is not selfigniting.
Auto igniting:
Product does not present an explosion hazard.
Danger of explosion:
Not determined.
Density:
Solubility in / Miscibility with
Fully miscible.
Water:
7.5
pH-value at 20°C (68°F):
Solvent content:
0.0 %
Organic solvents:
46.1 %
Water:
53.4 %
Solids content:
USA
(Contd. on page 4)
DR
Page 4/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Protease Reagent
(Contd. of page 3)
10 Stability and reactivity
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Dangerous reactions Reacts with strong acids.
Dangerous products of decomposition:
Carbon monoxide and carbon dioxide
Nitrogen oxides (NOx)
Sulfur oxides (SOx)
11 Toxicological information
Acute toxicity:
LD/LC50 values that are relevant for classification:
7783-20-2 ammonium sulphate
Oral LD50 3000 mg/kg (Rat)
Primary irritant effect:
on the skin: Irritant to skin and mucous membranes.
on the eye: Irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information:
The product shows the following dangers according to internally approved calculation methods for preparations:
Irritant
12 Ecological information
General notes:
Water hazard class 1 (Self-assessment): slightly hazardous for water
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
13 Disposal considerations
Product:
Recommendation:
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings:
Recommendation: Disposal must be made according to official regulations.
Recommended cleansing agent: Water, if necessary with cleansing agents.
* 14 Transport information
Contact Promega Safety Department for additional transportation information
DOT regulations:
Not regulated
-
Hazard class:
(Contd. on page 5)
USA
DR
Page 5/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Protease Reagent
(Contd. of page 4)
Land transport ADR/RID (cross-border):
ADR/RID class: -
Maritime transport IMDG:
-
IMDG Class:
Marine pollutant: No
Air transport ICAO-TI and IATA-DGR:
ICAO/IATA Class: -
* 15 Regulations
Sara
Section 355 (extremely hazardous substances):
None of the ingredients are listed.
Section 313 (Specific toxic chemical listings):
7783-20-2 ammonium sulphate
TSCA (Toxic Substances Control Act):
7783-20-2 ammonium sulphate
7732-18-5 water, distilled, conductivity or of similar purity
1185-53-1 Tris(hydroxymethyl)aminomethane hydrochloride
Proposition 65
Chemicals known to cause cancer:
None of the ingredients are listed.
Chemicals known to cause reproductive toxicity for females:
None of the ingredients are listed.
Chemicals known to cause reproductive toxicity for males:
None of the ingredients are listed.
Chemicals known to cause developmental toxicity:
None of the ingredients are listed.
Cancerogenity categories
EPA (Environmental Protection Agency)
None of the ingredients are listed.
IARC (International Agency for Research on Cancer)
None of the ingredients are listed.
NTP (National Toxicology Program)
None of the ingredients are listed.
TLV (Threshold Limit Value established by ACGIH)
None of the ingredients are listed.
MAK (German Maximum Workplace Concentration)
None of the ingredients are listed.
NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients are listed.
(Contd. on page 6)
USA
DR
Page 6/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Protease Reagent
(Contd. of page 5)
OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients are listed.
Product related hazard informations:
The product has been classified and marked in accordance with directives on hazardous materials.
Hazard symbols:
Xi Irritant
Risk phrases:
Irritating to eyes, respiratory system and skin.
Safety phrases:
Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable gloves.
This material and its container must be disposed of as hazardous waste.
National regulations:
Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.
* 16 Other information
This information is based on our present knowledge. However, this shall not constitute a guarantee for any
specific product features and shall not establish a legally valid contractual relationship.
Department issuing MSDS:
Promega Corporation
Environmental Health and Safety Department
2800 Woods Hollow Road
Madison, WI
Ph:(608)274-4330
* Data compared to the previous version altered.
USA
DR
Page 1/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
* 1 Identification of substance
Trade name: Control AMC Substrate
Article number: V325
Application of the substance / the preparation Laboratory chemicals
Manufacturer/Supplier:
Promega Corporation
2800 Woods Hollow Road
Madison, WI 53711
U.S.A.
1-800-356-9526 or (608)-274-4330
MSDS author: Regulatory.Affairs@promega.com
Emergency information:
CHEMTREC 1-800-424-9300
for call originating outside the United States dial 001-703-527-3887
2 Composition/Data on components
Chemical characterization
Description: Mixture of the substances listed below with nonhazardous additions.
Dangerous components: Void
Additional information: For the wording of the listed risk phrases refer to section 15.
3 Hazards identification
Hazard description: Not applicable. Product has been classified as non-hazardous.
Information pertaining to particular dangers for man and environment:
The product does not have to be labelled due to the calculation procedure of international guidelines.
Classification system:
The classification was made according to the latest editions of international substances lists, and is expanded
upon by company and technical literature data.
NFPA ratings (scale 0 - 4)
Health = 0
Fire = 0
Reactivity = 0
HMIS-ratings (scale 0 - 4)
Health = 0
Fire =0
Reactivity = 0
Not applicable
OSHA Hazard Overview (Criteria according to 29CFR1910.1200):
Target Organ(s): Not applicable or unknown
USA
(Contd. on page 2)
DR
Page 2/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Control AMC Substrate
(Contd. of page 1)
4 First aid measures
General information: No special measures required.
After inhalation: Supply fresh air; consult doctor in case of complaints.
After skin contact: Generally the product does not irritate the skin.
After eye contact: Rinse opened eye for several minutes under running water.
After swallowing: If symptoms persist consult doctor.
5 Fire fighting measures
Suitable extinguishing agents:
CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
Protective equipment: No special measures required.
6 Accidental release measures
Person-related safety precautions: Not required.
Measures for environmental protection: Dilute with plenty of water.
Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Additional information: No dangerous substances are released.
7 Handling and storage
Handling:
Information for safe handling: No special measures required.
Information about protection against explosions and fires: No special measures required.
Storage:
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: None.
8 Exposure controls and personal protection
Components with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be monitored at
the workplace.
Additional information: The lists that were valid during the creation were used as basis.
Personal protective equipment:
General protective and hygienic measures:
The usual precautionary measures for handling chemicals should be followed.
Breathing equipment: Not required.
Protection of hands:
Protective gloves
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
(Contd. on page 3)
USA
DR
Page 3/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Control AMC Substrate
(Contd. of page 2)
Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance
of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Eye protection: Goggles recommended during refilling.
9 Physical and chemical properties
General Information
Fluid
Form:
Colorless
Color:
Characteristic
Odor:
Change in condition
Melting point/Melting range: 0°C (32°F)
Boiling point/Boiling range: Undetermined.
Not applicable.
Flash point:
Product is not selfigniting.
Auto igniting:
Product does not present an explosion hazard.
Danger of explosion:
1 g/cm³
Density at 20°C (68°F):
Solubility in / Miscibility with
Fully miscible.
Water:
Solvent content:
0.0 %
Organic solvents:
99.6 %
Water:
10 Stability and reactivity
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Dangerous reactions No dangerous reactions known.
Dangerous products of decomposition: No dangerous decomposition products known.
11 Toxicological information
Acute toxicity:
Primary irritant effect:
on the skin: No irritant effect.
on the eye: Irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information:
The product is not subject to classification according to internally approved calculation methods for
preparations:
When used and handled according to specifications, the product does not have any harmful effects according to
our experience and the information provided to us.
USA
(Contd. on page 4)
DR
Page 4/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Control AMC Substrate
(Contd. of page 3)
12 Ecological information
General notes: Generally not hazardous for water
13 Disposal considerations
Product:
Recommendation:
Smaller quantities can be disposed of with household waste.
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings:
Recommendation: Disposal must be made according to official regulations.
Recommended cleansing agent: Water, if necessary with cleansing agents.
* 14 Transport information
Contact Promega Safety Department for additional transportation information
DOT regulations:
Not regulated
-
Hazard class:
Land transport ADR/RID (cross-border):
ADR/RID class: -
Maritime transport IMDG:
-
IMDG Class:
Marine pollutant: No
Air transport ICAO-TI and IATA-DGR:
ICAO/IATA Class: -
15 Regulations
Sara
Section 355 (extremely hazardous substances):
None of the ingredients are listed.
Section 313 (Specific toxic chemical listings):
None of the ingredients are listed.
TSCA (Toxic Substances Control Act):
7732-18-5 water, distilled, conductivity or of similar purity
Proposition 65
Chemicals known to cause cancer:
None of the ingredients are listed.
Chemicals known to cause reproductive toxicity for females:
None of the ingredients are listed.
(Contd. on page 5)
USA
DR
Page 5/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Control AMC Substrate
(Contd. of page 4)
Chemicals known to cause reproductive toxicity for males:
None of the ingredients are listed.
Chemicals known to cause developmental toxicity:
None of the ingredients are listed.
Cancerogenity categories
EPA (Environmental Protection Agency)
None of the ingredients are listed.
IARC (International Agency for Research on Cancer)
None of the ingredients are listed.
NTP (National Toxicology Program)
None of the ingredients are listed.
TLV (Threshold Limit Value established by ACGIH)
None of the ingredients are listed.
MAK (German Maximum Workplace Concentration)
None of the ingredients are listed.
NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients are listed.
OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients are listed.
Product related hazard informations:
Observe the general safety regulations when handling chemicals.
The product is not subject to identification regulations according to directives on hazardous materials.
National regulations:
Water hazard class: Generally not hazardous for water.
* 16 Other information
This information is based on our present knowledge. However, this shall not constitute a guarantee for any
specific product features and shall not establish a legally valid contractual relationship.
Department issuing MSDS:
Promega Corporation
Environmental Health and Safety Department
2800 Woods Hollow Road
Madison, WI
Ph:(608)274-4330
* Data compared to the previous version altered.
USA
DR
Page 1/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
* 1 Identification of substance
Trade name: PTPase R110 Substrate
Article number: V345
Application of the substance / the preparation Laboratory chemicals
Manufacturer/Supplier:
Promega Corporation
2800 Woods Hollow Road
Madison, WI 53711
U.S.A.
1-800-356-9526 or (608)-274-4330
MSDS author: Regulatory.Affairs@promega.com
Emergency information:
CHEMTREC 1-800-424-9300
for call originating outside the United States dial 001-703-527-3887
2 Composition/Data on components
Chemical characterization
Description: Mixture of the substances listed below with nonhazardous additions.
Dangerous components:
1185-53-1 Tris(hydroxymethyl)aminomethane hydrochloride 5-10%
1336-21-6 ammonium hydroxide <1.00%
Additional information: For the wording of the listed risk phrases refer to section 15.
3 Hazards identification
Hazard description: Not applicable. Product has been classified as non-hazardous.
Information pertaining to particular dangers for man and environment:
The product does not have to be labelled due to the calculation procedure of international guidelines.
Classification system:
The classification was made according to the latest editions of international substances lists, and is expanded
upon by company and technical literature data.
NFPA ratings (scale 0 - 4)
Health = 0
Fire = 0
Reactivity = 0
HMIS-ratings (scale 0 - 4)
Health = 0
Fire =0
Reactivity = 0
Not applicable
OSHA Hazard Overview (Criteria according to 29CFR1910.1200):
(Contd. on page 2)
USA
DR
Page 2/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: PTPase R110 Substrate
(Contd. of page 1)
Target Organ(s): Not applicable or unknown
4 First aid measures
General information: No special measures required.
After inhalation: Supply fresh air; consult doctor in case of complaints.
After skin contact: Generally the product does not irritate the skin.
After eye contact: Rinse opened eye for several minutes under running water.
After swallowing: If symptoms persist consult doctor.
5 Fire fighting measures
Suitable extinguishing agents:
CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
Protective equipment: No special measures required.
6 Accidental release measures
Person-related safety precautions: Not required.
Measures for environmental protection:
Dilute with plenty of water.
Do not allow to enter sewers/ surface or ground water.
Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Additional information: No dangerous substances are released.
7 Handling and storage
Handling:
Information for safe handling: No special measures required.
Information about protection against explosions and fires: No special measures required.
Storage:
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: None.
8 Exposure controls and personal protection
Components with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be monitored at
the workplace.
Additional information: The lists that were valid during the creation were used as basis.
Personal protective equipment:
General protective and hygienic measures:
The usual precautionary measures for handling chemicals should be followed.
Breathing equipment: Not required.
Protection of hands:
Protective gloves
(Contd. on page 3)
USA
DR
Page 3/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: PTPase R110 Substrate
(Contd. of page 2)
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance
of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Eye protection: Goggles recommended during refilling.
9 Physical and chemical properties
General Information
Fluid
Form:
Colorless
Color:
Characteristic
Odor:
Change in condition
Melting point/Melting range: Undetermined.
Boiling point/Boiling range: 100°C (212°F)
Not applicable.
Flash point:
Product is not selfigniting.
Auto igniting:
Product does not present an explosion hazard.
Danger of explosion:
Not determined.
Density:
Solubility in / Miscibility with
Fully miscible.
Water:
Solvent content:
0.0 %
Organic solvents:
94.5 %
Water:
5.1 %
Solids content:
10 Stability and reactivity
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Dangerous reactions No dangerous reactions known.
Dangerous products of decomposition: No dangerous decomposition products known.
11 Toxicological information
Acute toxicity:
Primary irritant effect:
on the skin: No irritant effect.
on the eye: Irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information:
The product is not subject to classification according to internally approved calculation methods for
preparations:
(Contd. on page 4)
USA
DR
Page 4/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: PTPase R110 Substrate
(Contd. of page 3)
When used and handled according to specifications, the product does not have any harmful effects according to
our experience and the information provided to us.
12 Ecological information
General notes:
Water hazard class 1 (Self-assessment): slightly hazardous for water
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
13 Disposal considerations
Product:
Recommendation:
Smaller quantities can be disposed of with household waste.
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings:
Recommendation: Disposal must be made according to official regulations.
Recommended cleansing agent: Water, if necessary with cleansing agents.
* 14 Transport information
Contact Promega Safety Department for additional transportation information
DOT regulations:
Not regulated
-
Hazard class:
Land transport ADR/RID (cross-border):
ADR/RID class: -
Maritime transport IMDG:
-
IMDG Class:
Marine pollutant: No
Air transport ICAO-TI and IATA-DGR:
ICAO/IATA Class: -
15 Regulations
Sara
Section 355 (extremely hazardous substances):
None of the ingredients are listed.
Section 313 (Specific toxic chemical listings):
None of the ingredients are listed.
TSCA (Toxic Substances Control Act):
All ingredients are listed.
(Contd. on page 5)
USA
DR
Page 5/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: PTPase R110 Substrate
(Contd. of page 4)
Proposition 65
Chemicals known to cause cancer:
None of the ingredients are listed.
Chemicals known to cause reproductive toxicity for females:
None of the ingredients are listed.
Chemicals known to cause reproductive toxicity for males:
None of the ingredients are listed.
Chemicals known to cause developmental toxicity:
None of the ingredients are listed.
Cancerogenity categories
EPA (Environmental Protection Agency)
None of the ingredients are listed.
IARC (International Agency for Research on Cancer)
None of the ingredients are listed.
NTP (National Toxicology Program)
None of the ingredients are listed.
TLV (Threshold Limit Value established by ACGIH)
None of the ingredients are listed.
MAK (German Maximum Workplace Concentration)
None of the ingredients are listed.
NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients are listed.
OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients are listed.
Product related hazard informations:
Observe the general safety regulations when handling chemicals.
The product is not subject to identification regulations according to directives on hazardous materials.
National regulations:
Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.
* 16 Other information
This information is based on our present knowledge. However, this shall not constitute a guarantee for any
specific product features and shall not establish a legally valid contractual relationship.
Department issuing MSDS:
Promega Corporation
Environmental Health and Safety Department
2800 Woods Hollow Road
Madison, WI
Ph:(608)274-4330
* Data compared to the previous version altered.
USA
DR
Page 1/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
* 1 Identification of substance
Trade name: Sodium Vanadate, 100mM
Article number: V343
Application of the substance / the preparation Laboratory chemicals
Manufacturer/Supplier:
Promega Corporation
2800 Woods Hollow Road
Madison, WI 53711
U.S.A.
1-800-356-9526 or (608)-274-4330
MSDS author: Regulatory.Affairs@promega.com
Emergency information:
CHEMTREC 1-800-424-9300
for call originating outside the United States dial 001-703-527-3887
2 Composition/Data on components
Chemical characterization
Description: Mixture of the substances listed below with nonhazardous additions.
Dangerous components:
13721-39-6 Trisodium orthovanadate <2.00%
Additional information: For the wording of the listed risk phrases refer to section 15.
* 3 Hazards identification
Hazard description: Not applicable. Product has been classified as non-hazardous.
Information pertaining to particular dangers for man and environment:
The product does not have to be labelled due to the calculation procedure of international guidelines.
Classification system:
The classification was made according to the latest editions of international substances lists, and is expanded
upon by company and technical literature data.
NFPA ratings (scale 0 - 4)
Health = 0
Fire = 0
Reactivity = 0
HMIS-ratings (scale 0 - 4)
Health = 0
Fire =0
Reactivity = 0
Potentially Toxic
OSHA Hazard Overview (Criteria according to 29CFR1910.1200):
Target Organ(s): Not applicable or unknown
USA
(Contd. on page 2)
DR
Page 2/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Sodium Vanadate, 100mM
(Contd. of page 1)
* 4 First aid measures
General information: No special measures required.
After inhalation: Supply fresh air; consult doctor in case of complaints.
After skin contact: Generally the product does not irritate the skin.
After eye contact: Rinse opened eye for several minutes under running water.
After swallowing: If symptoms persist consult doctor.
* 5 Fire fighting measures
Suitable extinguishing agents:
CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
Protective equipment: No special measures required.
* 6 Accidental release measures
Person-related safety precautions: Not required.
Measures for environmental protection: Dilute with plenty of water.
Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Additional information: No dangerous substances are released.
* 7 Handling and storage
Handling:
Information for safe handling: No special measures required.
Information about protection against explosions and fires: No special measures required.
Storage:
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: None.
* 8 Exposure controls and personal protection
Components with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be monitored at
the workplace.
Additional information: The lists that were valid during the creation were used as basis.
Personal protective equipment:
General protective and hygienic measures:
The usual precautionary measures for handling chemicals should be followed.
Breathing equipment: Not required.
Protection of hands:
Protective gloves
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
(Contd. on page 3)
USA
DR
Page 3/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Sodium Vanadate, 100mM
(Contd. of page 2)
Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance
of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Eye protection: Goggles recommended during refilling.
* 9 Physical and chemical properties
General Information
Fluid
Form:
Colorless
Color:
Characteristic
Odor:
Change in condition
Melting point/Melting range: 0°C (32°F)
Boiling point/Boiling range: 100°C (212°F)
Not applicable.
Flash point:
Product is not selfigniting.
Auto igniting:
Product does not present an explosion hazard.
Danger of explosion:
1 g/cm³
Density at 20°C (68°F):
Solubility in / Miscibility with
Fully miscible.
Water:
Solvent content:
0.0 %
Organic solvents:
98.2 %
Water:
1.8 %
Solids content:
10 Stability and reactivity
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Dangerous reactions No dangerous reactions known.
Dangerous products of decomposition: No dangerous decomposition products known.
* 11 Toxicological information
Acute toxicity:
Primary irritant effect:
on the skin: No irritant effect.
on the eye: Irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information:
The product is not subject to classification according to internally approved calculation methods for
preparations:
(Contd. on page 4)
USA
DR
Page 4/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Sodium Vanadate, 100mM
(Contd. of page 3)
When used and handled according to specifications, the product does not have any harmful effects according to
our experience and the information provided to us.
12 Ecological information
General notes: Generally not hazardous for water
* 13 Disposal considerations
Product:
Recommendation:
Smaller quantities can be disposed of with household waste.
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings:
Recommendation: Disposal must be made according to official regulations.
Recommended cleansing agent: Water, if necessary with cleansing agents.
* 14 Transport information
Contact Promega Safety Department for additional transportation information
DOT regulations:
Not regulated
-
Hazard class:
Land transport ADR/RID (cross-border):
ADR/RID class: -
Maritime transport IMDG:
-
IMDG Class:
Marine pollutant: No
Air transport ICAO-TI and IATA-DGR:
ICAO/IATA Class: -
* 15 Regulations
Sara
Section 355 (extremely hazardous substances):
None of the ingredients are listed.
Section 313 (Specific toxic chemical listings):
None of the ingredients are listed.
TSCA (Toxic Substances Control Act):
All ingredients are listed.
Proposition 65
Chemicals known to cause cancer:
None of the ingredients are listed.
(Contd. on page 5)
USA
DR
Page 5/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: Sodium Vanadate, 100mM
(Contd. of page 4)
Chemicals known to cause reproductive toxicity for females:
None of the ingredients are listed.
Chemicals known to cause reproductive toxicity for males:
None of the ingredients are listed.
Chemicals known to cause developmental toxicity:
None of the ingredients are listed.
Cancerogenity categories
EPA (Environmental Protection Agency)
None of the ingredients are listed.
IARC (International Agency for Research on Cancer)
None of the ingredients are listed.
NTP (National Toxicology Program)
None of the ingredients are listed.
TLV (Threshold Limit Value established by ACGIH)
None of the ingredients are listed.
MAK (German Maximum Workplace Concentration)
None of the ingredients are listed.
NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients are listed.
OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients are listed.
Product related hazard informations:
Observe the general safety regulations when handling chemicals.
The product is not subject to identification regulations according to directives on hazardous materials.
National regulations:
Water hazard class: Generally not hazardous for water.
* 16 Other information
This information is based on our present knowledge. However, this shall not constitute a guarantee for any
specific product features and shall not establish a legally valid contractual relationship.
Department issuing MSDS:
Promega Corporation
Environmental Health and Safety Department
2800 Woods Hollow Road
Madison, WI
Ph:(608)274-4330
* Data compared to the previous version altered.
USA
DR
Page 1/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
* 1 Identification of substance
Trade name: 5X Reaction Buffer B
Article number: V334
Application of the substance / the preparation Laboratory chemicals
Manufacturer/Supplier:
Promega Corporation
2800 Woods Hollow Road
Madison, WI 53711
U.S.A.
1-800-356-9526 or (608)-274-4330
MSDS author: Regulatory.Affairs@promega.com
Emergency information:
CHEMTREC 1-800-424-9300
for call originating outside the United States dial 001-703-527-3887
2 Composition/Data on components
Chemical characterization
Description: Mixture of the substances listed below with nonhazardous additions.
Dangerous components:
1185-53-1 Tris(hydroxymethyl)aminomethane hydrochloride 1.0-5.0%
Additional information: For the wording of the listed risk phrases refer to section 15.
3 Hazards identification
Hazard description: Not applicable. Product has been classified as non-hazardous.
Information pertaining to particular dangers for man and environment:
The product does not have to be labelled due to the calculation procedure of international guidelines.
Classification system:
The classification was made according to the latest editions of international substances lists, and is expanded
upon by company and technical literature data.
NFPA ratings (scale 0 - 4)
Health = 0
Fire = 0
Reactivity = 0
HMIS-ratings (scale 0 - 4)
Health = 0
Fire =0
Reactivity = 0
Not applicable
OSHA Hazard Overview (Criteria according to 29CFR1910.1200):
Target Organ(s): Not applicable or unknown
USA
(Contd. on page 2)
DR
Page 2/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: 5X Reaction Buffer B
(Contd. of page 1)
4 First aid measures
General information: No special measures required.
After inhalation: Supply fresh air; consult doctor in case of complaints.
After skin contact: Generally the product does not irritate the skin.
After eye contact: Rinse opened eye for several minutes under running water.
After swallowing: If symptoms persist consult doctor.
5 Fire fighting measures
Suitable extinguishing agents:
CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
Protective equipment: No special measures required.
6 Accidental release measures
Person-related safety precautions: Not required.
Measures for environmental protection: Dilute with plenty of water.
Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Additional information: No dangerous substances are released.
7 Handling and storage
Handling:
Information for safe handling: No special measures required.
Information about protection against explosions and fires: No special measures required.
Storage:
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: None.
8 Exposure controls and personal protection
Components with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be monitored at
the workplace.
Additional information: The lists that were valid during the creation were used as basis.
Personal protective equipment:
General protective and hygienic measures:
The usual precautionary measures for handling chemicals should be followed.
Breathing equipment: Not required.
Protection of hands:
Protective gloves
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
(Contd. on page 3)
USA
DR
Page 3/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: 5X Reaction Buffer B
(Contd. of page 2)
Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance
of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Eye protection: Goggles recommended during refilling.
9 Physical and chemical properties
General Information
Fluid
Form:
Colorless
Color:
Characteristic
Odor:
Change in condition
Melting point/Melting range: 0°C (32°F)
Boiling point/Boiling range: 100°C (212°F)
Not applicable.
Flash point:
Product is not selfigniting.
Auto igniting:
Product does not present an explosion hazard.
Danger of explosion:
1 g/cm³
Density at 20°C (68°F):
Solubility in / Miscibility with
Fully miscible.
Water:
Solvent content:
0.0 %
Organic solvents:
97.4 %
Water:
2.5 %
Solids content:
10 Stability and reactivity
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Dangerous reactions No dangerous reactions known.
Dangerous products of decomposition: No dangerous decomposition products known.
11 Toxicological information
Acute toxicity:
Primary irritant effect:
on the skin: No irritant effect.
on the eye: Irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information:
The product is not subject to classification according to internally approved calculation methods for
preparations:
(Contd. on page 4)
USA
DR
Page 4/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: 5X Reaction Buffer B
(Contd. of page 3)
When used and handled according to specifications, the product does not have any harmful effects according to
our experience and the information provided to us.
12 Ecological information
General notes: Generally not hazardous for water
13 Disposal considerations
Product:
Recommendation:
Smaller quantities can be disposed of with household waste.
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings:
Recommendation: Disposal must be made according to official regulations.
Recommended cleansing agent: Water, if necessary with cleansing agents.
* 14 Transport information
Contact Promega Safety Department for additional transportation information
DOT regulations:
Not regulated
-
Hazard class:
Land transport ADR/RID (cross-border):
ADR/RID class: -
Maritime transport IMDG:
-
IMDG Class:
Marine pollutant: No
Air transport ICAO-TI and IATA-DGR:
ICAO/IATA Class: -
15 Regulations
Sara
Section 355 (extremely hazardous substances):
None of the ingredients are listed.
Section 313 (Specific toxic chemical listings):
None of the ingredients are listed.
TSCA (Toxic Substances Control Act):
All ingredients are listed.
Proposition 65
Chemicals known to cause cancer:
None of the ingredients are listed.
(Contd. on page 5)
USA
DR
Page 5/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: 5X Reaction Buffer B
(Contd. of page 4)
Chemicals known to cause reproductive toxicity for females:
None of the ingredients are listed.
Chemicals known to cause reproductive toxicity for males:
None of the ingredients are listed.
Chemicals known to cause developmental toxicity:
None of the ingredients are listed.
Cancerogenity categories
EPA (Environmental Protection Agency)
None of the ingredients are listed.
IARC (International Agency for Research on Cancer)
None of the ingredients are listed.
NTP (National Toxicology Program)
None of the ingredients are listed.
TLV (Threshold Limit Value established by ACGIH)
None of the ingredients are listed.
MAK (German Maximum Workplace Concentration)
None of the ingredients are listed.
NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients are listed.
OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients are listed.
Product related hazard informations:
Observe the general safety regulations when handling chemicals.
The product is not subject to identification regulations according to directives on hazardous materials.
National regulations:
Water hazard class: Generally not hazardous for water.
* 16 Other information
This information is based on our present knowledge. However, this shall not constitute a guarantee for any
specific product features and shall not establish a legally valid contractual relationship.
Department issuing MSDS:
Promega Corporation
Environmental Health and Safety Department
2800 Woods Hollow Road
Madison, WI
Ph:(608)274-4330
* Data compared to the previous version altered.
USA
DR
Page 1/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
* 1 Identification of substance
Trade name: 5X Termination Buffer C
Article number: V346
Application of the substance / the preparation Laboratory chemicals
Manufacturer/Supplier:
Promega Corporation
2800 Woods Hollow Road
Madison, WI 53711
U.S.A.
1-800-356-9526 or (608)-274-4330
MSDS author: Regulatory.Affairs@promega.com
Emergency information:
CHEMTREC 1-800-424-9300
for call originating outside the United States dial 001-703-527-3887
2 Composition/Data on components
Chemical characterization
Description: Mixture of the substances listed below with nonhazardous additions.
Dangerous components:
1185-53-1 Tris(hydroxymethyl)aminomethane hydrochloride 1.0-5.0%
Additional information: For the wording of the listed risk phrases refer to section 15.
3 Hazards identification
Hazard description: Not applicable. Product has been classified as non-hazardous.
Information pertaining to particular dangers for man and environment:
The product does not have to be labelled due to the calculation procedure of international guidelines.
Classification system:
The classification was made according to the latest editions of international substances lists, and is expanded
upon by company and technical literature data.
NFPA ratings (scale 0 - 4)
Health = 0
Fire = 0
Reactivity = 0
HMIS-ratings (scale 0 - 4)
Health = 0
Fire =0
Reactivity = 0
Not applicable
OSHA Hazard Overview (Criteria according to 29CFR1910.1200):
Target Organ(s): Not applicable or unknown
USA
(Contd. on page 2)
DR
Page 2/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: 5X Termination Buffer C
(Contd. of page 1)
4 First aid measures
General information: No special measures required.
After inhalation: Supply fresh air; consult doctor in case of complaints.
After skin contact: Generally the product does not irritate the skin.
After eye contact: Rinse opened eye for several minutes under running water.
After swallowing: If symptoms persist consult doctor.
5 Fire fighting measures
Suitable extinguishing agents:
CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
Protective equipment: No special measures required.
6 Accidental release measures
Person-related safety precautions: Not required.
Measures for environmental protection: Dilute with plenty of water.
Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Additional information: No dangerous substances are released.
7 Handling and storage
Handling:
Information for safe handling: No special measures required.
Information about protection against explosions and fires: No special measures required.
Storage:
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: None.
8 Exposure controls and personal protection
Components with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be monitored at
the workplace.
Additional information: The lists that were valid during the creation were used as basis.
Personal protective equipment:
General protective and hygienic measures:
The usual precautionary measures for handling chemicals should be followed.
Breathing equipment: Not required.
Protection of hands:
Protective gloves
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
(Contd. on page 3)
USA
DR
Page 3/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: 5X Termination Buffer C
(Contd. of page 2)
Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance
of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Eye protection: Goggles recommended during refilling.
9 Physical and chemical properties
General Information
Fluid
Form:
Colorless
Color:
Characteristic
Odor:
Change in condition
Melting point/Melting range: 0°C (32°F)
Boiling point/Boiling range: 100°C (212°F)
Not applicable.
Flash point:
Product is not selfigniting.
Auto igniting:
Product does not present an explosion hazard.
Danger of explosion:
1 g/cm³
Density at 20°C (68°F):
Solubility in / Miscibility with
Fully miscible.
Water:
Solvent content:
0.0 %
Organic solvents:
97.4 %
Water:
2.6 %
Solids content:
10 Stability and reactivity
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Dangerous reactions No dangerous reactions known.
Dangerous products of decomposition: No dangerous decomposition products known.
11 Toxicological information
Acute toxicity:
Primary irritant effect:
on the skin: No irritant effect.
on the eye: Irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information:
The product is not subject to classification according to internally approved calculation methods for
preparations:
(Contd. on page 4)
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Page 4/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: 5X Termination Buffer C
(Contd. of page 3)
When used and handled according to specifications, the product does not have any harmful effects according to
our experience and the information provided to us.
12 Ecological information
General notes: Generally not hazardous for water
13 Disposal considerations
Product:
Recommendation:
Smaller quantities can be disposed of with household waste.
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings:
Recommendation: Disposal must be made according to official regulations.
Recommended cleansing agent: Water, if necessary with cleansing agents.
* 14 Transport information
Contact Promega Safety Department for additional transportation information
DOT regulations:
Not regulated
-
Hazard class:
Land transport ADR/RID (cross-border):
ADR/RID class: -
Maritime transport IMDG:
-
IMDG Class:
Marine pollutant: No
Air transport ICAO-TI and IATA-DGR:
ICAO/IATA Class: -
15 Regulations
Sara
Section 355 (extremely hazardous substances):
None of the ingredients are listed.
Section 313 (Specific toxic chemical listings):
None of the ingredients are listed.
TSCA (Toxic Substances Control Act):
All ingredients are listed.
Proposition 65
Chemicals known to cause cancer:
None of the ingredients are listed.
(Contd. on page 5)
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Page 5/5
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 06/23/2008 Reviewed on 06/23/2008
Trade name: 5X Termination Buffer C
(Contd. of page 4)
Chemicals known to cause reproductive toxicity for females:
None of the ingredients are listed.
Chemicals known to cause reproductive toxicity for males:
None of the ingredients are listed.
Chemicals known to cause developmental toxicity:
None of the ingredients are listed.
Cancerogenity categories
EPA (Environmental Protection Agency)
None of the ingredients are listed.
IARC (International Agency for Research on Cancer)
None of the ingredients are listed.
NTP (National Toxicology Program)
None of the ingredients are listed.
TLV (Threshold Limit Value established by ACGIH)
None of the ingredients are listed.
MAK (German Maximum Workplace Concentration)
None of the ingredients are listed.
NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients are listed.
OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients are listed.
Product related hazard informations:
Observe the general safety regulations when handling chemicals.
The product is not subject to identification regulations according to directives on hazardous materials.
National regulations:
Water hazard class: Generally not hazardous for water.
* 16 Other information
This information is based on our present knowledge. However, this shall not constitute a guarantee for any
specific product features and shall not establish a legally valid contractual relationship.
Department issuing MSDS:
Promega Corporation
Environmental Health and Safety Department
2800 Woods Hollow Road
Madison, WI
Ph:(608)274-4330
* Data compared to the previous version altered.
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