Page 1/5
Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 26.06.2008 Revision: 26.06.2008
Not classified as hazardous according to criteria of Worksafe Australia
* 1 Identification of substance
Trade name: Caspase-Glo庐 9 Substrate
Article number: G816
Application of the substance / the preparation: Laboratory chemicals
Manufacturer/Supplier:
Promega Corporation
2800 Woods Hollow Road
Madison, WI 53711
U.S.A.
1-608-274-4330
1-800-356-9526
MSDS author: Regulatory.Affairs@promega.com
Further information obtainable from:
37 Nelson Street
Annandale NSW 2038
AUSTRALIA
Sydney
Tel: (61) 02 9565 1100
Fax: (61) 02 9550 4454
Toll free Tel: 1800 225 123
Toll free Fax: 1800 626 017
Melbourne
Tel: (61) 03 9818 1466
Fax: (61) 03 9818 1244
Toll free Tel: 1800 335 435
E-mail Address: aus_custserv@au.promega.com
Web Address: www.promega.com/au/
Information in case of emergency:
CHEMTREC 1-800-424-9300
For call originating outside the United States dial 001-703-527-3887
2 Hazards identification
Hazard description: not applicable
Information concerning to particular hazards to man and environment
The product does not have to be labelled due to the calculation procedure of the "General Classification
guideline for preparations of the EU" in the latest valid version.
Classification system:
The classification is in line with current EC lists. It is extended, by information from technical literature and
company information.
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(Contd. on page 2)
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Page 2/5
Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 26.06.2008 Revision: 26.06.2008
Trade name: Caspase-Glo庐 9 Substrate
(Contd. of page 1)
3 Composition/information on ingredients
Chemical characterization
Description: Mixture of substances listed below with nonhazardous additions.
Components:
CAS: 3483-12-3 Dithiothreitol 1.0-5.0%
RTECS: XO8576500
Additional information: For the wording of the listed risk phrases refer to section 16.
* 4 First aid measures
General information: No special measures required.
After inhalation: Supply fresh air; consult doctor in case of complaints.
After skin contact: Generally the product does not irritate the skin.
After eye contact: Rinse opened eye for several minutes under running water.
After swallowing: If symptoms persist consult doctor.
* 5 Fire fighting measures
Suitable extinguishing agents: Use fire extinguishing methods suitable to surrounding conditions.
Protective equipment: No special measures required.
* 6 Accidental release measures
Person-related safety precautions: Not required.
Measures for environmental protection: Do not allow to enter sewers/ surface or ground water.
Measures for cleaning/collecting: Pick up mechanically.
Additional information: No dangerous substances are released.
* 7 Handling and storage
Handling
Information for safe handling: No special measures required.
Information about fire - and explosion protection: No special measures required.
Storage
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: None.
* 8 Exposure controls and personal protection gear
Additional information about design of technical facilities: No further data; see item 7.
Ingredients with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be monitored at
the workplace.
Additional information: The lists valid during the making were used as basis.
(Contd. on page 3)
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Page 3/5
Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 26.06.2008 Revision: 26.06.2008
Trade name: Caspase-Glo庐 9 Substrate
(Contd. of page 2)
Personal protective equipment
General protective and hygienic measures
The usual precautionary measures are to be adhered to when handling chemicals.
Respiratory protection: Not required.
Protection of hands:
Protective gloves.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
Material of gloves:
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance
of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Penetration time of glove material:
The exact break trough time has to be found out by the manufacturer of the protective gloves and has to be
observed.
Eye protection: Not required.
* 9 Physical and chemical properties
General Information
Solid.
Form:
Colourless
Colour:
Characteristic
Odour:
Change in condition
Melting point/Melting range: undetermined
Boiling point/Boiling range: 130掳C (266掳F)
> 100掳C (> 212掳F)
Flash point:
Product is not selfigniting.
Self-igniting:
Product does not present an explosion hazard.
Danger of explosion:
Not determined
Density:
Solubility in / Miscibility with
Slightly soluble
Water:
Solvent content:
0.0 %
Organic solvents:
90.3 %
Water:
45.3 %
Solids content:
10 Stability and reactivity
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Dangerous reactions: No dangerous reactions known
Dangerous decomposition products:
Carbon monoxide and carbon dioxide
Nitrogen oxides
Sulphur oxides (SOx)
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(Contd. on page 4)
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Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 26.06.2008 Revision: 26.06.2008
Trade name: Caspase-Glo庐 9 Substrate
(Contd. of page 3)
* 11 Toxicological information
Acute toxicity:
Primary irritant effect:
on the skin: No irritant effect.
on the eye: Irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information:
The product is not subject to classification according to the calculation method of the General EU Classification
Guidelines for Preparations as issued in the latest version.
When used and handled according to specifications, the product does not have any harmful effects to our
experience and the information provided to us.
* 12 Ecological information
General notes:
Water hazard class 2 (German Regulation) (Self-assessment): hazardous for water.
Do not allow product to reach ground water, water course or sewage system.
Danger to drinking water if even small quantities leak into the ground.
* 13 Disposal considerations
Product:
Recommendation
Smaller quantities can be disposed of with household waste.
Must not be disposed together with household garbage. Do not allow product to reach sewage system.
Uncleaned packaging:
Recommendation: Disposal must be made according to official regulations.
* 14 Transport information
Land transport ADR/RID (cross-border) Not regulated
-
ADR/RID class:
Not regulated
Maritime transport IMDG:
-
IMDG Class:
No
Marine pollutant:
Air transport ICAO-TI and IATA-DGR:
-
ICAO/IATA Class:
* 15 Regulations
Australian Inventory of Chemical Substances
7732-18-5 water, distilled, conductivity or of similar purity
3483-12-3 Dithiothreitol
75277-39-3 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid sodium salt
(Contd. on page 5)
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Page 5/5
Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 26.06.2008 Revision: 26.06.2008
Trade name: Caspase-Glo庐 9 Substrate
(Contd. of page 4)
7647-14-5 sodium chloride
56-65-5 adenosine 5'-triphosphate
10034-99-8 Magnesium sulfate heptahydrate
4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid potassium salt
6381-92-6 Ethylenediaminetetra-acetic acid, disodium salt
Labelling according to EU guidelines:
Observe the general safety regulations when handling chemicals
The product is not subject to identification regulations under EU Directives and the Ordinance on Hazardous
Materials (German GefStoffV).
Special labelling of certain preparations:
Safety data sheet available for professional user on request.
National regulations
Waterhazard class: Water hazard class 2 (Self-assessment): hazardous for water.
* 16 Other information
This information is based on our present knowledge. However, this shall not constitute a guarantee for any
specific product features and shall not establish a legally valid contractual relationship.
Department issuing MSDS:
Promega Corporation
Safety Department
2800 Woods Hollow Road
Madison, WI 53711
U.S.A.
Contact:
Promega Corporation
37 Nelson Street
Annandale NSW 2038, Australia
* Data compared to the previous version altered.
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