Valid 08/1999 - 10/1999
Fluka Chemical Corp.
1001 West St. Paul
Milwaukee, WI 53233 USA
Tel: 414-273-3850
MATERIAL SAFETY DATA SHEET
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CATALOG #: 15335
NAME: LEAD(II) NITRATE
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 10099-74-8
MF: N2O6PB
EC NO: 233-245-9
SYNONYMS
LEAD DINITRATE * LEAD(2+) NITRATE * LEAD(II) NITRATE * NITRIC ACID,
LEAD(2+) SALT * NITRATE DE PLOMB (FRENCH) * PLUMBOUS NITRATE *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
OXIDIZING
TOXIC
CONTACT WITH COMBUSTIBLE MATERIAL MAY CAUSE FIRE.
MAY IMPAIR FERTILITY.
MAY CAUSE HARM TO THE UNBORN CHILD.
HARMFUL BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.
DANGER OF CUMULATIVE EFFECTS.
CALIF. PROP. 65 CARCINOGEN.
TARGET ORGAN(S):
BLOOD
CENTRAL NERVOUS SYSTEM
KEEP AWAY FROM COMBUSTIBLE MATERIAL.
AVOID EXPOSURE - OBTAIN SPECIAL INSTRUCTIONS BEFORE USE.
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN.
WASH CONTAMINATED CLOTHING BEFORE REUSE.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
WATER SPRAY.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
STRONG OXIDIZER.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
CONTACT WITH OTHER MATERIAL MAY CAUSE FIRE.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
EVACUATE AREA.
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
COVER WITH DRY LIME OR SODA ASH, PICK UP, KEEP IN A CLOSED CONTAINER
AND HOLD FOR WASTE DISPOSAL.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
ADDITIONAL INFORMATION
A MIXTURE OF ALUMINUM POWDER, WATER AND METAL NITRATE MAY EXPLODE DUE
TO A SELF-ACCELERATING REACTION. MIXTURES OF METAL NITRATES WITH
ALKYL ESTERS MAY EXPLODE, OWING TO THE FORMATION OF ALKYL NITRATES.
MIXTURES OF A NITRATE WITH PHOSPHOROUS, TIN (2) CHLORIDE OR OTHER
REDUCING AGENTS MAY REACT EXPLOSIVELY. MIXTURES OF METAL NITRATES AND
PHOSPHINATES EXPLODE ON HEATING. MIXTURES CONTAINING NITRATES,
NITRITES, AND ORGANIC MATERIALS ARE POTENTIALLY DANGEROUS, ESPECIALLY
IN THE PRESENCE OF ACIDIC MATERIALS AND HEAVY METALS. INCOMPATIBLE
WITH: CYANIDES, THIOCYANATES, ISOTHIOCYANATES, HYPOPHOSPHITES.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT
GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.
USE ONLY IN A CHEMICAL FUME HOOD.
SAFETY SHOWER AND EYE BATH.
DO NOT BREATHE DUST.
DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
KEEP TIGHTLY CLOSED.
DO NOT STORE NEAR, NOR ALLOW CONTACT WITH, CLOTHING AND OTHER
COMBUSTIBLE MATERIAL.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
WHITE CRYSTALLINE POWDER
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
STABILITY
STABLE.
INCOMPATIBILITIES
STRONG REDUCING AGENTS
ORGANIC MATERIALS
FINELY POWDERED METALS
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
NITROGEN OXIDES
LEAD/LEAD OXIDES
HAZARDOUS POLYMERIZATION
WILL NOT OCCUR.
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN.
CAUSES EYE AND SKIN IRRITATION.
MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER
RESPIRATORY TRACT.
ABSORPTION INTO THE BODY LEADS TO THE FORMATION OF METHEMOGLOBIN
WHICH IN SUFFICIENT CONCENTRATION CAUSES CYANOSIS. ONSET MAY BE
DELAYED 2 TO 4 HOURS OR LONGER.
CHRONIC EFFECTS
A CARCINOGENIC RISK ASSESSMENT BY THE US EPA CLASSIFIES LEAD AND
INORGANIC LEAD COMPOUNDS AS B2 - INADEQUATE HUMAN EVIDENCE, SUFFICIENT
ANIMAL EVIDENCE. THE ANIMAL DATA IS FROM STUDIES USING LEAD SALTS,
PRIMARILY PHOSPHATES AND ACETATES. THERE IS NO EVIDENCE THAT ANY OF
THE STUDIES CITED IN THIS ASSESSMENT USED LEAD NITRATE.
MAY CAUSE REPRODUCTIVE DISORDERS.
MAY CAUSE CONGENITAL MALFORMATION IN THE FETUS.
TARGET ORGAN(S):
BLOOD, KIDNEYS
NERVES
FEMALE REPRODUCTIVE SYSTEM
MALE REPRODUCTIVE SYSTEM
TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND
TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
ADDITIONAL INFORMATION
LEAD SALTS HAVE BEEN REPORTED TO CROSS THE PLACENTA AND TO INDUCE
EMBRYO- AND FETO- MORTALITY. THEY ALSO HAVE TERATOGENIC EFFECT IN
SOME ANIMAL SPECIES. NO TERATOGENIC EFFECTS HAVE BEEN REPORTED WITH
EXPOSURE TO ORGANOMETALLIC LEAD COMPOUNDS. ADVERSE EFFECTS OF LEAD ON
HUMAN REPRODUCTION, EMBRYONIC AND FETAL DEVELOPMENT AND POSTNATAL
(E.G., MENTAL) DEVELOPMENT HAVE BEEN REPORTED. EXCESSIVE EXPOSURE CAN
AFFECT BLOOD, NERVOUS AND DIGESTIVE SYSTEMS. THE SYNTHESIS OF
HEMOGLOBIN IS INHIBITED AND RESULTS IN ANEMIA. IF LEFT UNTREATED,
NEUROMUSCULAR DYSFUNCTION, POSSIBLE PARALYSIS AND ENCEPHALOPATHY CAN
RESULT. ADDITIONAL SYMPTOMS OF OVEREXPOSURE INCLUDE: JOINT AND MUSCLE
PAIN, WEAKNESS OF THE EXTENSOR MUSCLES (FREQUENTLY THE HAND AND
WRIST), HEADACHE, DIZZINESS, ABDOMINAL PAIN, DIARRHEA, CONSTIPATION,
NAUSEA, VOMITING, BLUE LINE ON THE GUMS, INSOMNIA AND METALLIC TASTE.
HIGH BODY LEVELS PRODUCE INCREASED CEREBROSPINAL PRESSURE, BRAIN
DAMAGE, STUPOR LEADING TO COMA AND OFTEN DEATH.
RTECS #: OG2100000
LEAD(II) NITRATE (1:2)
TOXICITY DATA
IVN-RAT LD50:93 MG/KG PSEBAA 92,331,1956
UNR-RAT LD50:3613 MG/KG GISAAA 50(3),57,1985
IPR-MUS LD50:74 MG/KG BECTA6 9,80,1973
TARGET ORGAN DATA
BEHAVIORAL (CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD)
BLOOD (PIGMENTED OR NUCLEATED RBC)
PATERNAL EFFECTS (TESTES, EPIDIDYMIS, SPERM DUCT)
MATERNAL EFFECTS (PARTURITION)
EFFECTS ON FERTILITY (POST-IMPLANTATION MORTALITY)
EFFECTS ON FERTILITY (OTHER MEASURES OF FERTILITY)
EFFECTS ON EMBRYO OR FETUS (EXTRA EMBRYONIC STRUCTURES)
EFFECTS ON EMBRYO OR FETUS (FETOTOXICITY)
EFFECTS ON EMBRYO OR FETUS (FETAL DEATH)
SPECIFIC DEVELOPMENTAL ABNORMALITIES (CENTRAL NERVOUS SYSTEM)
SPECIFIC DEVELOPMENTAL ABNORMALITIES (BODY WALL)
SPECIFIC DEVELOPMENTAL ABNORMALITIES (MUSCULOSKELETAL SYSTEM)
SPECIFIC DEVELOPMENTAL ABNORMALITIES (CARDIOVASCULAR SYSTEM)
SPECIFIC DEVELOPMENTAL ABNORMALITIES (UROGENITAL SYSTEM)
SPECIFIC DEVELOPMENTAL ABNORMALITIES (HOMEOSTASIS)
SPECIFIC DEVELOPMENTAL ABNORMALITIES (OTHER DEVELOPMENTAL ABNORMALITIES)
EFFECTS ON NEWBORN (WEANING OR LACTATION INDEX)
EFFECTS ON NEWBORN (GROWTH STATISTICS)
EFFECTS ON NEWBORN (BEHAVIORAL)
NUTRITIONAL AND GROSS METABOLIC (BODY TEMPERATURE DECREASE)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
CONTACT A LICENSED PROFESSIONAL WASTE DISPOSAL SERVICE TO DISPOSE OF
THIS MATERIAL.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT FLUKA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
EC INDEX NO: 082-001-00-6
OXIDIZING
TOXIC
R 60
MAY IMPAIR FERTILITY.
R 61
MAY CAUSE HARM TO THE UNBORN CHILD.
R 20/22
HARMFUL BY INHALATION AND IF SWALLOWED.
R 33
DANGER OF CUMULATIVE EFFECTS.
S 53
AVOID EXPOSURE - OBTAIN SPECIAL INSTRUCTIONS BEFORE USE.
S 45
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
ACGIH TLV-TWA 0.05 MG(PB)/M3; ANIMAL CARCINOGEN DTLVS* TLV/BEI,1997
IARC CANCER REVIEW:ANIMAL INADEQUATE EVIDENCE IMEMDT 23,325,1980
OEL-ARAB REPUBLIC OF EGYPT:TWA 0.05 MG(PB)/M3 JAN 1993
OEL-AUSTRALIA:TWA 0.15 MG(PB)/M3 JAN 1993
OEL-AUSTRIA:TWA 0.1 MG(PB)/M3 JAN 1993
OEL-BELGIUM:TWA 0.15 MG(PB)/M3 JAN 1993
OEL-DENMARK:TWA 0.1 MG(PB)/M3 JAN 1993
OEL-FINLAND:TWA 0.1 MG(PB)/M3 JAN 1993
OEL-FRANCE:TWA 0.15 MG(PB)/M3 JAN 1993
OEL-GERMANY:TWA 0.1 MG(PB)/M3 JAN 1993
OEL-HUNGARY:STEL 0.04 MG(PB)/M3;CARCINOGEN JAN 1993
OEL-THE PHILIPPINES:TWA 0.15 MG(PB)/M3 JAN 1993
OEL-RUSSIA:STEL 0.005 PPM (0.01 MG(PB)/M3) JAN 1993
OEL-SWEDEN:TWA 0.05 MG(PB)/M3 (RESP. DUST) JAN 1993
OEL-SWEDEN:TWA 0.1 MG(PB)/M3 (TOTAL DUST) JAN 1993
OEL-SWITZERLAND:TWA 0.1 MG(PB)/M3 JAN 1993
OEL-THAILAND:TWA 0.2 MG(PB)/M3 JAN 1993
OEL-TURKEY:TWA 0.2 MG(PB)/M3 JAN 1993
OEL-UNITED KINGDOM:TWA 0.15 MG(PB)/M3 JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA CHECK ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV
NIOSH REL TO LEAD, INORGANIC-AIR:10H TWA <0.1 MG(PB)/M3
NIOSH* DHHS #92-100,1992
NOHS 1974: HZD 84473; NIS 4; TNF 112; NOS 5; TNE 420
NOES 1983: HZD 84473; NIS 18; TNF 450; NOS 20; TNE 11440; TFE 4246
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
U.S. INFORMATION
THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS -
LEAD COMPOUNDS.
CALIFORNIA PROPOSITION 65:
THIS PRODUCT IS OR CONTAINS CHEMICAL(S) KNOWN TO THE STATE OF
CALIFORNIA TO CAUSE CANCER.
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1998 SIGMA-ALDRICH CO.
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
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