BASF Corporation
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Material Safety Data Sheet
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Page :1
Original Date: 07/07/2000
Revision Date: 11/03/2003
BASF CORPORATION
1609 BIDDLE AVENUE
WYANDOTTE, MI 48192
(734) 324-5244
EMERGENCY TELEPHONE: (800) 424-9300 CHEMTREC
(800) 832-HELP (BASF Hotline)
BOTH NUMBERS ARE AVAILABLE DAYS, NIGHTS, WEEKENDS, & HOLIDAYS.
SECTION 1 - PRODUCT INFORMATION
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LUPRANATE庐M20FB ISOCYANATE
Product ID: NPU 578705
Common Chemical Name:
DIPHENYLMETHANE DIISOCYANATE BLEND
Synonyms:
N/A
Molecular Formula:
MIXTURE
Chemical Family: Aromatic Isocyanates
Molecular Wt.: NOT ESTABLISHED
SECTION 2 - INGREDIENTS
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Chemical Name: CAS Amount
4,4' DIPHENYLMETHANE DIISOCYANATE 101-68-8 38.0 %
ACGIH TLV TWA 0.005 PPM
OSHA PEL CEIL 0.02 PPM
POLYMERIC MDI 9016-87-9 < 55.0 %
PEL/TLV NOT ESTABLISHED
MDI MIXED ISOMERS 26447-40-5 < 10.0 %
PEL/TLV NOT ESTABLISHED
SECTION 3 - HAZARDS IDENTIFICATION
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Emergency Overview
Color: Dark Brown
Form/Appearance: Liquid
Odor: Aromatic
WARNING STATEMENT:
CAUTION:
CONTAINS DIPHENYLMETHANE DIISOCYANATE (CAS NO. 101-68-8).
INHALATION OF MDI MISTS OR VAPORS MAY CAUSE RESPIRATORY IRRITATION,
BREATHLESSNESS, CHEST DISCOMFORT AND REDUCED PULMONARY FUNCTION.
OVEREXPOSURE WELL ABOVE THE PEL MAY RESULT IN BRONCHITIS, BRONCHIAL
SPASMS AND PULMONARY EDEMA. LONG-TERM EXPOSURE TO ISOCYANATES HAS
BEEN REPORTED TO CAUSE LUNG DAMAGE, INCLUDING REDUCED LUNG FUNCTION
WHICH MAY BE PERMANENT. ACUTE OR CHRONIC OVEREXPOSURE TO ISOCYANATES
MAY CAUSE SENSITIZATION IN SOME INDIVIDUALS, RESULTING IN ALLERGIC
LUPRANATE庐M20FB ISOCYANATE
NPU 578705 Page : 2
SECTION 3 - HAZARDS IDENTIFICATION (cont)
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RESPIRATORY REACTIONS INCLUDING WHEEZING, SHORTNESS OF BREATH AND
DIFFICULTY BREATHING.
Potential Health Effects
Primary Routes of Exposure:
Routes of entry for solids and liquids include eye and skin
contact, ingestion and inhalation. Routes of entry for gases
include inhalation and eye contact. Skin contact may be a route
of entry for liquified gases.
Acute Overexposure Effects:
Eye contact with isocyanates may result in conjunctival irritation
and mild corneal opacity. Skin contact may result in dermatitis,
either irritative or allergic.
Inhalation of MDI vapors may cause irritation of the mucous mem-
branes of the nose, throat or trachea, breathlessness, chest dis-
comfort, difficult breathing and reduced pulmonary function. Air-
borne overexposure well above the PEL may result additionally in eye
irritation, headache, chemical bronchitis, asthma-like findings or
pulmonary edema. Isocyanates have also been reported to cause hyper-
sensitivity pneumonitis, which is characterized by flu-like symptoms,
the onset of which may be delayed. Gastrointestinal symptoms
include nausea, vomiting and abdominal pain.
Chronic Overexposure Effects:
Results from a lifetime inhalation study in rats indicate that MDI
aerosol was carcinogenic at 6 mg/m3, the highest dose tested. This is
well above the recommended TLV of 5 ppb (0.05 mg/m3). Only irritation
was noted at the lower concentration of 0.2 and 1 mg/m3. No birth
defects or teratogenic effects were reported in a teratology study
with rats exposed to 1, 4, and 12 mg/m3 polymeric MDI for 6 hr/day
on days 6-15 of gestation. Embryotoxicity and fetotoxicity was
reported at the top dose in the presence of maternal toxicity.
As a result of previous repeated overexposures or a single large
dose, certain individuals will develop isocyanate sensitization
(chemical asthma) which will cause them to react to a later exposure
to isocyanate at levels well below the PEL/TLV. These symptoms,
which include chest tightness, wheezing, cough, shortness of breath,
or asthmatic attack, could be immediate or delayed up to several
hours after exposure. Similar to many non-specific asthmatic
responses, there are reports that once sensitized an individual can
experience these symptoms upon exposure to dust, cold air, or other
irritants. This increased lung sensitivity can persist for weeks and
in severe cases for several years. Chronic overexposure to
isocyanates has also been reported to cause lung damage, including
a decrease in lung function, which may be permanent. Sensitization
may be either temporary or permanent. Prolonged contact can cause
reddening, swelling, rash, scaling, or blistering. In those who have
developed a skin sensitization, these symptoms can develop as a
result of contact with very small amounts of liquid material, or even
as a result of vapor-only exposure.
First Aid Procedures - Aggravated Medical Conditions:
Individuals who are sensitized to isocyanates and those with pre-
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SECTION 3 - HAZARDS IDENTIFICATION (cont)
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exisiting lung diseases or conditions, including non-specific
bronchial hyperreactivity or asthma, must avoid all exposure to
isocyanates.
SECTION 4 - FIRST AID MEASURES
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First Aid Procedures - Skin:
Wash affected areas with soap and water. Remove and launder
contaminated clothing before reuse. Get immediate medical attention.
First Aid Procedures - Eyes:
Immediately rinse eyes with running water for 15 minutes. Get
immediate medical attention.
First Aid Procedures - Ingestion:
If swallowed, dilute with water. DO NOT INDUCE VOMITING. Never
give fluids or induce vomiting if the victim is unconscious or having
convulsions. Get immediate medical attention.
First Aid Procedures - Inhalation:
Move to fresh air. Aid in breathing, if necessary, and get
immediate medical attention.
First Aid Procedures - Notes to Physicians:
There is no specific antidote to counteract the effects of MDI.
Care should be supportive and treatment should be based on the
judgement of the physician in response to the reaction of the
patient.
First Aid Procedures - Aggravated Medical Conditions:
Individuals who are sensitized to isocyanates and those with pre-
exisiting lung diseases or conditions, including non-specific
bronchial hyperreactivity or asthma, must avoid all exposure to
isocyanates.
First Aid Procedures - Special Precautions:
None
Other First Aid Procedures:
Medical supervision of all employees who handle or come into contact
with MDI is recommended. Preemployment and periodic medical exami-
nations with respiratory function tests (FEV, FVC as a minimum are
suggested). Persons with asthmatic conditions chronic bronchitis,
other chronic respiratory diseases, recurrent eczema or pulmonary
sensitization should be excluded from working with MDI. Once a
person is diagnosed as having pulmonary sensitization (allergic
asthma) to MDI, further exposure is not permissible.
SECTION 5 - FIRE FIGHTING MEASURES
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Typical Low/High Deg. Method
Flash Point: 200 C CLEVELAND OPEN CUP
Autoignition: NOT AVAILABLE
Extinguishing Media:
Use water, dry extinguishing media, carbon dioxide (CO2) or foam.
Fire Fighting Procedures:
Personnel engaged in fighting isocyanate fires must be protected
against nitrogen dioxide fumes as well as isocyanate vapors.
Firefighters must wear self-contained breathing apparatus and
LUPRANATE庐M20FB ISOCYANATE
NPU 578705 Page : 4
SECTION 5 - FIRE FIGHTING MEASURES (cont)
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turnout gear.
Unusual Hazards:
Reacts exothermically with water to form carbon dioxide gas, which
may create excessive pressure in closed containers. Reacts
exothermically with polyol and alcohols. Reacts exothermically and
possibly violently with acids, amines and alkaline solutions.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
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General:
General:
Evacuate and ventilate spill area, dike spill to prevent entry into
water system, wear full protective equipment including respiratory
equipment during clean up.
MAJOR SPILL:
Call BASF Corporation @ 1-800-832-4357. If transportation spill
involved, call CHEMTREC @ 1-800-424-9300. If temporary control of
isocyanate vapor is required a blanket of protein foam or other
suitable foam (available at most fire departments), may be placed
over the spill. Transfer as much liquid as possible via pump or
vacuum device into closed but not sealed containers for disposal.
MINOR SPILL:
Absorb the isocyanate with an acceptable absorbent, see 40 CFR
sections 260, 264, and 265 for further information. Shovel into open
containers. Do not make pressure tight. Move to a well ventilated
area (outside) and neutralize with a mixture of 90% water, 3-8%
ammonia and 2-7% detergent. Add at 10 to 1 ratio. Let stand for 48
hours letting evolved CO2 escape. Proceed with final clean up of
spill area.
CLEAN UP:
Decontaminate spill area using neutralizing solution and let stand
for at least 10 minutes.
SECTION 7 - STORAGE AND HANDLING
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General:
Keep containers closed and store in well-ventilated area at 60-80
deg. F. Outage of container should be filled with dry inert gas at
atmospheric pressure to avoid reaction with moisture. Contamination
by moisture or basic compounds can cause dangerous pressure buildup
in closed containers.
Other Storage and Handling Data:
If bulging of drum occurs, transfer to well ventilated area, puncture
to relieve pressure, open vent and let stand for 48 hours before
resealing.
SECTION 8 - PERSONAL PROTECTION
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Clothing:
Rubber gloves, coveralls, hard hat, boots and rubber apron to avoid
skin contact. Contaminated equipment or clothing should be cleaned
after each use or disposed of.
Eyes:
Wear fitted chemical goggles or face shield and safety glasses.
LUPRANATE庐M20FB ISOCYANATE
NPU 578705 Page :5
SECTION 8 - PERSONAL PROTECTION (cont)
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Respiration:
For situations where the airborne concentrations may exceed the level
for which an air purifying respirator is effective, or where the
levels are unknown or Immediately Dangerous to Life or Health (IDLH),
select and use an appropriate positive pressure air supplying
respirator (airline or self-contained breathing apparatus). When
atmospheric levels may exceed the occupational exposure limit (PEL
or TLV) approved air-purifying respirators equipped with an organic
vapor sorbent and particulate filter can be used as long as
appropriate precautions and change out schedules are in place.
Ventilation:
Use local exhaust as necessary to maintain P.E.L.
Explosion Proofing:
None required.
Other Personal Protection Data:
Eyewash fountains and safety showers must be easily accessible.
Maintain work area below P.E.L.
SECTION 9 - PHYSICAL PROPERTIES
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Color: Dark Brown
Form/Appearance: Liquid
Odor: Aromatic
Odor Intensity: Slight
Typical Low/High U.O.M.
Specific Gravity: NOT AVAILABLE
Bulk Density: 10.2 LB/GAL
Viscosity: 200 CENTIPOISE @ 25 DEG.
pH: NOT AVAILABLE
Typical Low/High Deg. @ Pressure
Boiling Pt: 200 C 5 MM HG
Freezing Pt: NOT AVAILABLE
Decomp. Tmp: NOT AVAILABLE
Solubility in Water Description: Water reactive
Vapor pressure <0.00001 MM Hg @20 deg. C
SECTION 10 - STABILITY AND REACTIVITY
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Stability Data:
Stable.
Incompatability:
Water, alcohols and strong bases.
Conditions/Hazards to Avoid:
Reaction with moisture may form CO2.
Hazardous Decomposition/Polymerization:
Hazardous decomposition products: CO, NOx, HCN and MDI vapors.
Polymerization: May occur.
Corrosive Properties:
Not corrosive.
LUPRANATE庐M20FB ISOCYANATE
NPU 578705 Page : 6
SECTION 10 - STABILITY AND REACTIVITY (cont)
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Oxidizer Properties:
Not an oxidizer
Other Reactivity Data:
Hazardous polymerization may occur. Avoid contamination with
moisture and other products that react with isocyanates.
Contact with certain rubbers and plastics can cause imbrittlement
of the material with subsequent loss in strength.
SECTION 11 - TOXICOLOGICAL INFORMATION
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Toxicology Test Data:
Rat, Oral LD50 - > 10,000 MG/KG
Practically Nontoxic
Mouse, Acute Intraperitoneal LD50 - 100 MG/KG
Toxic
Rat, 1 hr Inhalation LC50 - >2240 MG/CU. M
Moderately Toxic
SECTION 12 - ECOLOGICAL INFORMATION
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Environmental Toxicity Test Data:
Daphnia Magna, 24 hr EC/LC50 - > 500 MG/L
Practically Nontoxic
Zebra Fish, Static 24 hr LC50 - > 500 MG/L
Practically Nontoxic
SECTION 13 - DISPOSAL CONSIDERATION
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Waste Disposal:
Incinerate or landfill in a licensed facility. Do not discharge into
waterways or sewer systems.
Container Disposal:
Steel drums must be emptied (as defined by RCRA, Section 261.7 or
state regulations that may be more stringent) and can be sent to a
licensed drum reconditioner for reuse, a scrap metal dealer, or an
approved landfill. Check with reconditioner to determine if they
require them to be decontaminated. Drums destined for a scrap dealer
or landfill must be decontaminated and punctured or crushed to
prevent reuse.
SECTION 14 - TRANSPORTATION INFORMATION
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DOT Proper Shipping Name:
SEE BELOW
DOT Technical Name:
SEE BELOW
DOT Primary Hazard Class:
SEE BELOW
DOT Secondary Hazard Class:
SEE BELOW
DOT Label Required:
SEE BELOW
DOT Placard Required:
SEE BELOW
LUPRANATE庐M20FB ISOCYANATE
NPU 578705 Page : 7
SECTION 14 - TRANSPORTATION INFORMATION (cont)
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DOT Poison Constituent:
SEE BELOW
BASF Commodity Codes: UN/NA Code: E/R Guide:
Bill of Lading Description:
< 793 GALLONS NOT REGULATED BY THE DEPARTMENT OF TRANSPORTATION
> 793 GALLONS RQ, OTHER REGULATED SUBSTANCES, LIQUID, NOS, (MDI), 9,
NA3082, PG III
SECTION 15 - REGULATORY INFORMATION
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TSCA Inventory Status
Listed on Inventory: YES
SARA - 313 Listed Chemicals:
CAS: 28 AMOUNT: 100.0 %
NAME: DIIOSCYANATES
RCRA Haz. Waste No .: NO
CERCLA: YES Reportable Qty.: (If YES)
XXXXXXX XXXXXXXXXXXXXX 5000 LBS
SECTION 16 - OTHER INFORMATION
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Hazard Ratings:
BASF currently uses the National Paint & Coating Association (NPCA)
rating system. The use of an asterisk (*) in the HMIS rating
indicates the potential for chronic health effects.
Health: Fire: Reactivity: Special:
HMIS 2 1 1 NA
"IMPORTANT: WHILE THE DESCRIPTIONS, DESIGNS, DATA AND INFORMATION
CONTAINED HEREIN ARE PRESENTED IN GOOD FAITH AND BELIEVED TO BE
ACCURATE, IT IS PROVIDED FOR YOUR GUIDANCE ONLY. BECAUSE MANY FACTORS
MAY AFFECT PROCESSING OR APPLICATION/USE, WE RECOMMEND THAT YOU MAKE
TESTS TO DETERMINE THE SUITABILITY OF A PRODUCT FOR YOUR PARTICULAR
PURPOSE PRIOR TO USE. NO WARRANTIES OF ANY KIND, EITHER EXPRESSED OR
IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A
PARTICULAR PURPOSE, ARE MADE REGARDING PRODUCTS DESCRIBED OR DESIGNS,
DATA OR INFORMATION SET FORTH, OR THAT THE PRODUCTS, DESIGNS, DATA
OR INFORMATION MAY BE USED WITHOUT INFRINGING THE INTELLECTUAL
PROPERTY RIGHTS OF OTHERS. IN NO CASE SHALL THE DESCRIPTIONS,
INFORMATION, DATA OR DESIGNS PROVIDED BE CONSIDERED A PART OF OUR
TERMS AND CONDITIONS OF SALE. FURTHER, YOU EXPRESSLY UNDERSTAND AND
AGREE THAT THE DESCRIPTIONS, DESIGNS, DATA, AND INFORMATION FURNISHED
BY BASF HEREUNDER ARE GIVEN GRATIS AND BASF ASSUMES NO OBLIGATION OR
LIABILITY FOR THE DESCRIPTION, DESIGNS, DATA AND INFORMATION GIVEN
OR RESULTS OBTAINED, ALL SUCH BEING GIVEN AND ACCEPTED AT YOUR RISK".
BASF CORPORATION WILL NOT MAKE ITS PRODUCTS AVAILABLE TO CUSTOMERS
FOR USE IN THE MANUFACTURE OF MEDICAL DEVICES WHICH ARE INTENDED FOR
PERMANENT IMPLANTATION IN THE HUMAN BODY OR IN PERMANENT CONTACT WITH
INTERNAL BODILY TISSUES OR FLUIDS. WE AT BASF TAKE PRIDE IN OUR
PRODUCTS, AND OUR TRADITION OF DEVELOPING INNOVATIVE APPLICATIONS IN
PARTNERSHIP WITH OUR CUSTOMERS. HOWEVER, THE POSSIBILITY OF BEING
LUPRANATE庐M20FB ISOCYANATE
NPU 578705 Page : 8
SECTION 16 - OTHER INFORMATION (cont)
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REQUIRED TO RESPOND TO UNFOUNDED LITIGATION AND/OR CLAIMS ARISING
OUT OF CONCERNS RELATING TO SUCH USE PRESENTS AN UNACCEPTABLE RISK
TO THE COMPANY.
END OF DATA SHEET
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