DIMETHYL SULPHOXIDE 0459
October 2000
CAS No: 67-68-5 Methyl sulphoxide
DMSO
RTECS No: PV6210000
C2H6OS / (CH3)2SO
Molecular mass: 78.1
TYPES OF
ACUTE HAZARDS/SYMPTOMS PREVENTION FIRST AID/FIRE FIGHTING
HAZARD/
EXPOSURE
FIRE Combustible. Gives off irritating or NO open flames. Water spray, foam, powder, carbon
toxic fumes (or gases) in a fire. dioxide.
EXPLOSION Above 87/C explosive vapour/air Above 87/C use a closed system, In case of fire: keep drums, etc., cool
mixtures may be formed. ventilation, and explosion-proof by spraying with water.
electrical equipment.
EXPOSURE PREVENT GENERATION OF
MISTS! STRICT HYGIENE!
Inhalation Headache. Nausea. Ventilation, local exhaust, or breathing Fresh air, rest.
protection.
Skin MAY BE ABSORBED! Dry skin. Protective gloves. Protective clothing. Remove contaminated clothes.
Rinse and then wash skin with water
and soap. Refer for medical
attention.
Eyes Redness. Blurred vision. Safety spectacles. First rinse with plenty of water for
several minutes (remove contact
lenses if easily possible), then take to
a doctor.
Ingestion Nausea. Vomiting. Drowsiness. Do not eat, drink, or smoke during Do NOT induce vomiting. Refer for
work. medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Ventilation. Collect leaking and spilled liquid in
sealable containers as far as possible. Absorb
remaining liquid in sand or inert absorbent and
remove to safe place. Special attention to avoid skin
absorption. Personal protection: filter respirator for
organic gases and vapours.
EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H1; F1; R0 Separated from strong oxidants. Cool. Keep in the dark. Keep in a
well-ventilated room.
Prepared in the context of cooperation between the International
IPCS Programme on Chemical Safety and the European Commission 漏
IPCS 2005
International
Programme on
SEE IMPORTANT INFORMATION ON THE BACK.
Chemical Safety
0459 DIMETHYL SULPHOXIDE
IMPORTANT DATA
Physical State; Appearance Routes of exposure
COLOURLESS, HYGROSCOPIC LIQUID The substance can be absorbed into the body by inhalation,
through the skin and by ingestion.
Physical dangers
Inhalation risk
The vapour is heavier than air and may travel along the ground;
distant ignition possible. No indication can be given about the rate in which a harmful
concentration in the air is reached on evaporation of this
Chemical dangers substance at 20/C.
The substance decomposes on heating or on burning producing
Effects of short-term exposure
toxic fumes including sulfur oxides. Reacts violently with strong
oxidants such as perchlorates. The substance is irritating to the eyes and the skin. Exposure to
high concentrations of the substance could cause lowering of
Occupational exposure limits consciousness. May accelerate skin absorption of other materials
(see Notes).
TLV not established.
MAK: IIb (not established but data is available); skin absorption
Effects of long-term or repeated exposure
(H); (DFG 2004).
Repeated or prolonged contact with skin may cause dermatitis.
The substance may have effects on the liver and blood, resulting
in impaired functions and lesions of blood cells.
PHYSICAL PROPERTIES
Boiling point: 189/C Relative vapour density (air = 1): 2.7
Melting point: 18.5/C Flash point: 87/C c.c.
Relative density (water = 1): 1.1 Auto-ignition temperature: 215/C
Solubility in water: miscible Explosive limits, vol% in air: 2.6-42.0
Vapour pressure, Pa at 20/C: 59.4 Octanol/water partition coefficient as log Pow: -1.35 (calculated)
ENVIRONMENTAL DATA
NOTES
Special attention needed when toxic materials present in Dimethyl sulphoxide because of enhanced skin absorption.
Card has been partly updated in October 2005. See section Occupational Exposure Limits.
ADDITIONAL INFORMATION
Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible
LEGAL NOTICE for the use which might be made of this information
漏IPCS 2005
|