PROPIONIC ANHYDRIDE 0558
October 2005
CAS No: 123-62-6 Propanoic anhydride
Methylacetic anhydride
RTECS No: UF9100000
Propanoic acid anhydride
UN No: 2496
C6H10O3 / (CH3CH2CO)2O
EC No: 607-010-00-X
Molecular mass: 130.2
TYPES OF
ACUTE HAZARDS/SYMPTOMS PREVENTION FIRST AID/FIRE FIGHTING
HAZARD/
EXPOSURE
FIRE Combustible. NO open flames. Powder, alcohol-resistant foam,
water spray, carbon dioxide.
EXPLOSION Above 63/C explosive vapour/air Above 63/C use a closed system,
mixtures may be formed. ventilation.
EXPOSURE PREVENT GENERATION OF
MISTS! AVOID ALL CONTACT!
Inhalation Sore throat. Cough. Burning Ventilation, local exhaust, or breathing Fresh air, rest. Artificial respiration
sensation. Shortness of breath. protection. may be needed. Refer for medical
Symptoms may be delayed (see attention.
Notes).
Skin Pain. Skin burns. Protective gloves. Protective clothing. Remove contaminated clothes.
Rinse skin with plenty of water or
shower. Refer for medical attention.
Eyes Redness. Pain. Severe deep burns. Face shield or eye protection in First rinse with plenty of water for
combination with breathing several minutes (remove contact
protection. lenses if easily possible), then take to
a doctor.
Ingestion Burning sensation. Abdominal pain. Do not eat, drink, or smoke during Rinse mouth. Do NOT induce
Shock or collapse. Sore throat. work. vomiting. Give plenty of water to
drink. Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Personal protection: chemical protection suit. Use C Symbol Do not transport with food and
face shield. Collect leaking and spilled liquid in R: 34 feedstuffs.
sealable containers as far as possible. Absorb S: (1/2-)26-45
remaining liquid in dry sand or inert absorbent and UN Hazard Class: 8
remove to safe place. UN Pack Group: III
EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-80GC3-II+III Dry. Ventilation along the floor. Separated from bases, oxidants, food and
NFPA Code: H2; F2; R1 feedstuffs.
Prepared in the context of cooperation between the International
IPCS Programme on Chemical Safety and the European Commission 漏
IPCS 2005
International
Programme on
SEE IMPORTANT INFORMATION ON THE BACK.
Chemical Safety
0558 PROPIONIC ANHYDRIDE
IMPORTANT DATA
Physical State; Appearance Routes of exposure
COLOURLESS LIQUID, WITH PUNGENT ODOUR. The substance can be absorbed into the body by inhalation and
by ingestion.
Physical dangers
Inhalation risk
The vapour is heavier than air.
No indication can be given about the rate in which a harmful
Chemical dangers concentration in the air is reached on evaporation of this
substance at 20/C.
The substance decomposes on contact with water producing
corrosive propionic acid. Reacts violently with bases and oxidants
Effects of short-term exposure
causing fire and explosion hazard.
The substance is corrosive to the eyes, the skin and the
Occupational exposure limits respiratory tract. Inhalation of vapour or aerosol may cause lung
oedema (see Notes). Corrosive on ingestion. The effects may be
TLV not established.
delayed. Medical observation is indicated.
MAK not established.
PHYSICAL PROPERTIES
Boiling point: 167/C Relative vapour density (air = 1): 4.5
Melting point: -45/C Relative density of the vapour/air-mixture at 20/C (air = 1): 4.4
Relative density (water = 1): 1.01 Flash point: 63/C c.c.
Solubility in water: reaction Auto-ignition temperature: 285/C
Vapour pressure, kPa at 20/C: 0.1 Explosive limits, vol% in air: 1.3-9.5
ENVIRONMENTAL DATA
NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
ADDITIONAL INFORMATION
Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible
LEGAL NOTICE for the use which might be made of this information
漏IPCS 2005
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