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MSDS Material Safety Data Sheet
CAS

447-40-7
7447-40-7
3483-12-3
56-81-5

File Name: neb_com---msdsm0314.asp
                                        MATERIAL SAFETY DATA SHEET
Telephone: (978)927-5054
Murine RNase
Toll free: (800)632-5227
Inhibitor
Fax: (978)921-1350
New England Biolabs
e-mail: info@neb.com
#M0314
240 Country Road
Ipswich, MA 01938
Msds Revision Date: 8/08


SECTION 1鈥揅HEMICAL INFORMATION

Product Name: Murine RNase Inhibitor

1. Glycerol 50% Cas. #447-40-7
2. Potassium Chloride < 1% Cas. #7447-40-7
3. K-HEPES < 1% Cas. NA
4. Dithiothreitol < 1% Cas. #3483-12-3


SECTION 2鈥揅OMPOSITION/ INFORMATION ON INGREDIENT

CHEMICAL NAME: GLYCEROL
CAS No.: 56-81-5 Formula: C3H803 SARA 313: No
SYNONYMS: CITIFLOUR AF 2 * GLYCERIN * GLYCERIN, ANHYDROUS * GLYCERINE * GLYCERIN MIST (ACGIH, OSHA) * GLYCERIN,
SYNTHETIC * GLYCERITOL GLYCYL ALCOHOL * CLYZERIN, WASSERFREI (GERMAN) * GROCOLENE * OSMOGLYN * 1,2,3-PROPANE-
TRIOL * STAR * SYNTHETIC GLYCERIN * TECHNICAL GLYCERINE * TRIHYDROXYPROPANE * 1,2,3-TRIHYDROXYPROPANE.

RTECS Number: MA8050000


SECTION 3鈥揌AZARDOUS IDENTIFICATION

HMIS Rating NFPA Rating
Emergency Overview: Combustible. Avoid contact by
Health: 1* Health: 1
inhalation, skin and ingestion.Target organ(s): Kidney,
Hygroscopic Flammability: 0 Flammability: 0
Reactivity: 1 Reactivity: 1
* additional chronic hazards present.



SECTION 4鈥揊IRST AID MEASURES
Oral Exposure: If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation Exposure: If inhaled, remove to fresh air. If not breathing give artificial respiration.
If breathing is difficult, give oxygen. Call a physician.
Dermal Exposure: In case of contact, immediately wash skin with soap and copious amounts of water.
Eye Exposure: In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.
Assure adequate flushing by separating the eyelids with fingers. Call a physician.


SECTION 5鈥揊IRE FIGHTING MEASURES
Extinguishing Media: Water spray. Carbon Dioxide, dry chemical powder or appropriate foam.
Special Firefighting Procedures: Wear self contained breathing apparatus and protective clothing to prevent contact with
skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Flammability: N/A
SECTION 6鈥揂CCIDENTAL RELEASE MEASURES
Procedure(s) Of Personal Precaution(s): Wear self-contained breathing apparatus, rubber boots and heavy rubber gloves
and Chemical safety googles.
Methods For Cleaning Up: Cover with dry lime, sand, or soda ash. Place in covered containers using non-sparking tools
and transport outdoors. Ventilate area and wash spill site after material pickup is complete.
Environmental Precaution(s): Avoid contaminating water supply. Avoid contaminating sewers and waterways with this
material.



SECTION 7鈥揌ANDLING AND STORAGE

Handling: Avoid prolonged or repeated exposure.
User Exposure: Avoid Inhalation. Avoid contact with eyes, skin and clothing. Avoid prolonged or repeated exposure.
Storage: Keep tightly closed, away from sparks and open flames. Store in a cool dry place.
Special Requirements: Hygroscropic.


SECTION 8鈥揈XPOSURE CONTROLS/PPE
Engineering Controls: Safety shower and eye bath. Mechanical exhaust required.
Personal Protective Equipment: Goverment approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
Skin Specific: Chemical resistant
General Hygiene Measures: Wash hands thoroughly after handling. Wash contaminated clothing before use.


SECTION 9鈥揚HYSICAL AND CHEMICAL PROPERTIES
Explosion Limits in Air:
Physical Properties:
Lower: 0.9%
Melting Point: 20掳 C
Specific Gravity: 1.262
Boiling Point: 182掳 C
Solubility: Water -Z26130
Flash Point: 320 F, 160掳 C Method: closed up
Vapor Pressure: < 1 MMHG @ 20掳C
Autoignition Temp: 370掳
Vapor Density: 3.1 G/L
PH: 5.5鈥?8.0

SECTION 10鈥揝TABILITY AND REACTIVITY
Stability: Stable
Conditions to Avoid: Mosture, heat.
Materials to Avoid:Strong oxidizing agents,strong agents.
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
Hazardous Polymerization: Will not occur.


SECTION 11鈥揟OXICOLOGICAL INFORMATION
Route of Exposure:
Skin Absorption: May be harmful if absorbed.
Contact: May cause skin irritation.
Eye Contact:May cause eye irritation.
Inhalation: May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
To the best of our knowledge, the properties have not yet been thoroughly investigated.

Page 2
SECTION 12鈥揈COLOGICAL INFORMATION
Data not available at this time.


SECTION 13鈥揇ISPOSAL CONSIDERATIONS
Contact a licensed professional waste disposal service to dispose of this material.
Observe all federal state and local environmental regulations
Dissolve or mix the material with a combustIble solvent and burn in a chemical incinerator equipped with an afterburner and
scrubber.



SECTION 14鈥? TRANSPORT INFORMATION

DOT IATA
Proper Shipping Name: None Non-Hazardous for Air Transport

Non-hazardous for transport:
This substance is considered to be non-hazardous for transport


SECTION 15鈥揜EGULATORY INFORMATION

US Classification and Label Text:
EU Additional Classification
US Statements: Caution: Avoid contact and inhalation.
S: 23 24/25
Target Organ(s): Kidneys
Safety Statements: Do not breathe
vapor. Avoid contact with skin and
eyes.:

Canada Regulatory Information United States Regulatory Information:
Sara Listed: No
WHMIS Classification: This product has been
TSCA Inventory Item: Yes
classification in accordance with the hazard
criteria of the CPR and the MSDS contains all the
information required by the CPR

DSL: Yes
NDSL: No



SECTION 16鈥揙THER INFORMATION

DISCLAIMER:
For R&D use only. Not for drug, household or other uses.

New England Biolabs shall not be held liable
The above information is believed to be correct but
for any damage resulting from handling or from
does not purport to be all inclusive and shall be used
contact with the above product.
only as a guide.




Page 3

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