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@Beckman
CoulterTM Kit MSDS
Doc. ID: IM1459U-75: Rev. AA

Product Information

CD34 POOL Kit
Product Name
Doc. ID IM1459U-75 AA
Issued (year/month/day) 2004/01/23
Part Number IM1459U

IOTest�
Series Name:


Components
Description

CD34 POOL PE 100 Tests
ISOTYPIC CONTROL IgG1-PE/IgG2a-PE


Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.




�2004 Beckman Coulter, Inc.
Global MSDS � English
Page 2 of 11



@Beckman
CoulterTM MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identification

CD34 POOL PE 100
Product Name
Tests CD34 POOL Kit
Doc. ID IM1459U-75 AA
Issued (year/month/day) 2004/01/23
Part Number Component of P/N IM1459U


Product Use For laboratory use only. See product literature for details.
IOTest�
Series Name
Manufacturer Distributed by Beckman Coulter, Inc. for
IMMUNOTECH (A Beckman Coulter Company)
130, av.de Lattre de Tassigny—BP 177
13276 Marseille Cedex 09—France Tèl. (33) 4 91 17 27 00

¤
Distributor and Refer to attached list, Document ID: 472050, for local distributor and
Emergency Phone No. emergency phone numbers.


Section 2 Composition and Information on Ingredients
Hazardous Ingredients: Meets Hazardous Criteria:
Chemical Name CAS # % by wt. EU US OSHA WHMIS
Sodium Azide 26628-22-8 0.1% T+;R28 R32 No No
See Section 15 Regulatory Information for additional information on hazard classifications.


Section 3 Hazards Identification
Emergency Overview
Light yellow; Transparent; Liquid; Odorless
Nonflammable aqueous solution.
Harmful if swallowed.
Contains material of animal origin.


Physical Hazards Sodium azide forms explosive compounds with heavy metals. Repeated contact of
low concentrations of azide with lead and copper commonly found in plumbing drains
may result in the build up of shock sensitive compounds.

Potential Health This product contains material of animal origin and should be considered as
Effects Summary potentially capable of transmitting infectious diseases.
See Section 11 Toxicological Information for more detailed health information.

Product Hazard EU: WHMIS: US OSHA:
Classifications Xn;R22 Not applicable Not applicable
Beckman Coulter Safety Flammability (Section V): 0 Code
Rating Health (Section XI): 1 0=none
Reactivity with Water (Section X): 0 1=slight
Contact (Section VIII): 1 2=caution
3=severe
Doc. ID:
CD34 POOL Kit IM1459U-75 AA Page 3 of 11
CD34 POOL PE 100 Tests

Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Eye Contact If product enters eyes, wash eyes gently under running water for 15 minutes or
longer, making sure that the eyelids are held open. If pain or irritation occur, obtain
medical attention.
Skin Contact Remove any contaminated clothing. Wash affected area with plenty of soap and
water. Use disinfectant if possible.
Ingestion If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical
attention.


Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding fire.

Special Fire and None identified.
Explosion Hazards
Hazardous Combustion No combustion products posing significant hazards are expected from this product (a
Products dilute aqueous solution).
Protective Equipment Self-contained breathing apparatus is recommended for firefighters.
for Firefighters


Section 6 Accidental Release Measures
Personal Precautions This product contains a material of biological origin. Use universal precautions during
clean up procedures.
Spill and Leak As a precautionary measure, treat spilled material with a 1:10 bleach/water solution.
Procedures Absorb liquid and place in container suitable for disposal. Avoid generation of
aerosols during clean up. Comply with applicable waste disposal regulations.
Environmental Contain spill to prevent migration.
Precautions


Section 7 Handling and Storage
Handling Precautions This product should be handled as though capable of transmitting infectious diseases.
Universal precautions should be followed when using this product.
Recommended Storage Keep away from incompatible material.
Conditions To maintain efficacy, store according to the instructions in the product labeling.


Section 8 Exposure Controls and Personal Protection
Exposure Limits

US OSHA: None established
Doc. ID:
CD34 POOL Kit IM1459U-75 AA Page 4 of 11
CD34 POOL PE 100 Tests

Section 8 Exposure Controls and Personal Protection (Continued)
ACGIH:

Sodium Azide 0.29 mg/m3 Ceiling (as sodium azide); 0.11 ppm Ceiling (as
Hydrazoic acid, vapor)
DFG MAK:
Sodium Azide 0.2 mg/m3 MAK (inhalable fraction); 0.4 mg/m3 Peak (inhalable fraction)
Engineering Controls No special engineering controls are required. Use with good general ventilation.

Respiratory Protection Under normal conditions, the use of this product should not require respiratory
protection.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.

Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent skin
contact.


Section 9 Physical and Chemical Properties
Physical State Liquid

Color Light yellow
Transparency Transparent
Odor Odorless
Odor Threshold Not applicable
pH 7.2

Boiling Point Not available

Melting Point Not available

Specific Gravity 1.005 @20°C

Vapor Pressure Not available

Vapor Density Not available

Evaporation Rate Not available

Solubility
Water Miscible
Organic Not available


Section 10 Stability and Reactivity
Stability Stable in closed containers under normal temperatures and pressures.
Hazardous Strong acids
Incompatibilities Strong bases
Strong oxidizers
Metals and metallic compounds
Sodium azide forms explosive compounds with heavy metals. Repeated contact of
low concentrations of azide with lead and copper commonly found in plumbing drains
may result in the build up of shock sensitive compounds.
Doc. ID:
CD34 POOL Kit IM1459U-75 AA Page 5 of 11
CD34 POOL PE 100 Tests

Section 10 Stability and Reactivity (Continued)
Hazardous No decomposition products posing significant hazards would be expected from this
Decomposition Products product (a dilute aqueous solution).
Conditions to Avoid Avoid contact with incompatible materials.


Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Sodium Azide Oral LD50 Rat: 27 mg/kg; Oral LD50 Mouse: 27 mg/kg; Dermal LD50 Rabbit:
20 mg/kg
Primary Routes Common routes of entry include inhalation, ingestion and eye/skin contact. Specific
of Exposure paths of concern for potentially infectious materials are skin puncture, contact with
broken skin, contact with mucous membranes and inhalation of aerosolized material.
Potential Effects of This product contains material of animal origin and should be considered as
Acute Exposure potentially capable of transmitting infectious diseases.
Although its concentration in this product is low, sodium azide is highly toxic by
ingestion and skin absorption. Overexposure may result in irritation of skin, eyes and
mucous membranes, lowered blood pressure and irregular heartbeat. Sodium azide
is a chemical asphyxiant and may effect the cardiovascular, respiratory and central
nervous systems. Symptoms may include irritation, severe, pounding headaches,
dizziness, weakness, nausea, vomiting, low blood pressure, rapid heartbeat,
convulsions, collapse and death.
Potential Effects of Prolonged or repeated exposure to sodium azide may result in pounding headaches,
Chronic Exposure eye and nose irritation, low blood pressure, fatigue and dizziness.
Symptoms of Symptoms of overexposure may include: eye, skin, nose and throat irritation;
Overexposure headache, weakness, dizziness, confusion, nausea and vomiting. Severe cases
may exhibit difficulty in breathing, irregular heartbeat, reddish colored skin,
unconsciousness, convulsions, coma and death. Symptoms may be delayed for
several hours after exposure.
Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA
or 67/548/EEC Annex I.
Other Effects Reproductive effects have been reported in animal studies.

Conditions Aggravated None identified.
by Exposure


Section 12 Ecological Information
Ecotoxicity Toxic to fish and other water organisms.

Biodegradability No information available.

Mobility No information available.


Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance
with federal, state and local regulations. If unsure of the applicable requirements,
contact the authorities for information.
Sodium azide preservative may form explosive compounds in metal drain lines. See
NIOSH Bulletin: Explosive Azide Hazard (8/16/76).
Doc. ID:
CD34 POOL Kit IM1459U-75 AA Page 6 of 11
CD34 POOL PE 100 Tests

Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.


Section 15 Regulatory Information
US Federal and State Regulations

SARA 313 Sodium Azide is subject to reporting requirements of Section 313, Title III of SARA.
CERCLA RG’s, Sodium Azide is listed.
40 CFR 302.4
California Proposition 65 No ingredients listed
Massachusetts MSL Sodium Azide is listed.
New Jersey Dept. of Sodium Azide is listed.
Health RTK List
Pennsylvania RTK Sodium Azide is listed.


EU Labeling Classification
Classification Risk and Safety Phrases
Xn R22 Harmful if swallowed.
S28 After contact with skin, wash immediately with plenty of water.
Harmful


Canada
This product does not meet WHMIS criteria for hazardous materials.
PIN: Not applicable

Ingredients on Ingredient Sodium Azide
Disclosure List:
Ingredients with unknown None
toxicological properties:


Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.

WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE
OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.
Page 7 of 11



@Beckman
CoulterTM MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identification

ISOTYPIC CONTROL
Product Name
IgG1-PE/IgG2a-PE CD34 POOL Kit
Doc. ID IM1459U-75 AA
Issued (year/month/day) 2004/01/23
Part Number Component of P/N IM1459U


Product Use For laboratory use only. See product literature for details.
IOTest�
Series Name
Manufacturer Distributed by Beckman Coulter, Inc. for
IMMUNOTECH (A Beckman Coulter Company)
130, av.de Lattre de Tassigny—BP 177
13276 Marseille Cedex 09—France Tèl. (33) 4 91 17 27 00

¤
Distributor and Refer to attached list, Document ID: 472050, for local distributor and
Emergency Phone No. emergency phone numbers.


Section 2 Composition and Information on Ingredients
Hazardous Ingredients: Meets Hazardous Criteria:
Chemical Name CAS # % by wt. EU US OSHA WHMIS
Sodium Azide 26628-22-8 0.1% T+;R28 R32 No No
See Section 15 Regulatory Information for additional information on hazard classifications.


Section 3 Hazards Identification
Emergency Overview
Light yellow; Transparent; Liquid; Odorless
Nonflammable aqueous solution.
Harmful if swallowed.
Contains material of animal origin.


Physical Hazards Sodium azide forms explosive compounds with heavy metals. Repeated contact of
low concentrations of azide with lead and copper commonly found in plumbing drains
may result in the build up of shock sensitive compounds.

Potential Health This product contains material of animal origin and should be considered as
Effects Summary potentially capable of transmitting infectious diseases.
See Section 11 Toxicological Information for more detailed health information.

Product Hazard EU: WHMIS: US OSHA:
Classifications Xn;R22 Not applicable Not applicable
Beckman Coulter Safety Flammability (Section V): 0 Code
Rating Health (Section XI): 1 0=none
Reactivity with Water (Section X): 0 1=slight
Contact (Section VIII): 1 2=caution
3=severe
Doc. ID:
CD34 POOL Kit IM1459U-75 AA Page 8 of 11
ISOTYPIC CONTROL IgG1-PE/IgG2a-PE

Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Eye Contact If product enters eyes, wash eyes gently under running water for 15 minutes or
longer, making sure that the eyelids are held open. If pain or irritation occur, obtain
medical attention.
Skin Contact Remove any contaminated clothing. Wash affected area with plenty of soap and
water. Use disinfectant if possible.
Ingestion If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical
attention.


Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding fire.

Special Fire and None identified.
Explosion Hazards
Hazardous Combustion No combustion products posing significant hazards are expected from this product (a
Products dilute aqueous solution).
Protective Equipment Self-contained breathing apparatus is recommended for firefighters.
for Firefighters


Section 6 Accidental Release Measures
Personal Precautions This product contains a material of biological origin. Use universal precautions during
clean up procedures.
Spill and Leak As a precautionary measure, treat spilled material with a 1:10 bleach/water solution.
Procedures Absorb liquid and place in container suitable for disposal. Avoid generation of
aerosols during clean up. Comply with applicable waste disposal regulations.
Environmental Contain spill to prevent migration.
Precautions


Section 7 Handling and Storage
Handling Precautions This product should be handled as though capable of transmitting infectious diseases.
Universal precautions should be followed when using this product.
Recommended Storage Keep away from incompatible material.
Conditions To maintain efficacy, store according to the instructions in the product labeling.


Section 8 Exposure Controls and Personal Protection
Exposure Limits

US OSHA: None established
Doc. ID:
CD34 POOL Kit IM1459U-75 AA Page 9 of 11
ISOTYPIC CONTROL IgG1-PE/IgG2a-PE

Section 8 Exposure Controls and Personal Protection (Continued)
ACGIH:

Sodium Azide 0.29 mg/m3 Ceiling (as sodium azide); 0.11 ppm Ceiling (as
Hydrazoic acid, vapor)
DFG MAK:
Sodium Azide 0.2 mg/m3 MAK (inhalable fraction); 0.4 mg/m3 Peak (inhalable fraction)
Engineering Controls No special engineering controls are required. Use with good general ventilation.

Respiratory Protection Under normal conditions, the use of this product should not require respiratory
protection.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.

Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent skin
contact.


Section 9 Physical and Chemical Properties
Physical State Liquid

Color Light yellow
Transparency Transparent
Odor Odorless
Odor Threshold Not applicable
pH 7.2

Boiling Point Not available

Melting Point Not available

Specific Gravity 1.005 @20°C

Vapor Pressure Not available

Vapor Density Not available

Evaporation Rate Not available

Solubility
Water Miscible
Organic Not available


Section 10 Stability and Reactivity
Stability Stable in closed containers under normal temperatures and pressures.
Hazardous Strong acids
Incompatibilities Strong bases
Strong oxidizers
Metals and metallic compounds
Sodium azide forms explosive compounds with heavy metals. Repeated contact of
low concentrations of azide with lead and copper commonly found in plumbing drains
may result in the build up of shock sensitive compounds.
Doc. ID:
CD34 POOL Kit IM1459U-75 AA Page 10 of 11
ISOTYPIC CONTROL IgG1-PE/IgG2a-PE

Section 10 Stability and Reactivity (Continued)
Hazardous No decomposition products posing significant hazards would be expected from this
Decomposition Products product (a dilute aqueous solution).
Conditions to Avoid Avoid contact with incompatible materials.


Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Sodium Azide Oral LD50 Rat: 27 mg/kg; Oral LD50 Mouse: 27 mg/kg; Dermal LD50 Rabbit:
20 mg/kg
Primary Routes Common routes of entry include inhalation, ingestion and eye/skin contact. Specific
of Exposure paths of concern for potentially infectious materials are skin puncture, contact with
broken skin, contact with mucous membranes and inhalation of aerosolized material.
Potential Effects of This product contains material of animal origin and should be considered as
Acute Exposure potentially capable of transmitting infectious diseases.
Although its concentration in this product is low, sodium azide is highly toxic by
ingestion and skin absorption. Overexposure may result in irritation of skin, eyes and
mucous membranes, lowered blood pressure and irregular heartbeat. Sodium azide
is a chemical asphyxiant and may effect the cardiovascular, respiratory and central
nervous systems. Symptoms may include irritation, severe, pounding headaches,
dizziness, weakness, nausea, vomiting, low blood pressure, rapid heartbeat,
convulsions, collapse and death.
Potential Effects of Prolonged or repeated exposure to sodium azide may result in pounding headaches,
Chronic Exposure eye and nose irritation, low blood pressure, fatigue and dizziness.
Symptoms of Symptoms of overexposure may include: eye, skin, nose and throat irritation;
Overexposure headache, weakness, dizziness, confusion, nausea and vomiting. Severe cases
may exhibit difficulty in breathing, irregular heartbeat, reddish colored skin,
unconsciousness, convulsions, coma and death. Symptoms may be delayed for
several hours after exposure.
Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA
or 67/548/EEC Annex I.
Other Effects Reproductive effects have been reported in animal studies.

Conditions Aggravated None identified.
by Exposure


Section 12 Ecological Information
Ecotoxicity Toxic to fish and other water organisms.

Biodegradability No information available.

Mobility No information available.


Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance
with federal, state and local regulations. If unsure of the applicable requirements,
contact the authorities for information.
Sodium azide preservative may form explosive compounds in metal drain lines. See
NIOSH Bulletin: Explosive Azide Hazard (8/16/76).
Doc. ID:
CD34 POOL Kit IM1459U-75 AA Page 11 of 11
ISOTYPIC CONTROL IgG1-PE/IgG2a-PE

Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.


Section 15 Regulatory Information
US Federal and State Regulations

SARA 313 Sodium Azide is subject to reporting requirements of Section 313, Title III of SARA.
CERCLA RG’s, Sodium Azide is listed.
40 CFR 302.4
California Proposition 65 No ingredients listed
Massachusetts MSL Sodium Azide is listed.
New Jersey Dept. of Sodium Azide is listed.
Health RTK List
Pennsylvania RTK Sodium Azide is listed.


EU Labeling Classification
Classification Risk and Safety Phrases
Xn R22 Harmful if swallowed.
S28 After contact with skin, wash immediately with plenty of water.
Harmful


Canada
This product does not meet WHMIS criteria for hazardous materials.
PIN: Not applicable

Ingredients on Ingredient Sodium Azide
Disclosure List:
Ingredients with unknown None
toxicological properties:


Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.

WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE
OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.

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