Page 1 of 5
@Beckman
CoulterTM MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identi铿乧ation
PROGESTERONE RECEPTOR 6ml
Product Name
Doc. ID IM2146-75 AA
Issued (year/month/day) 2001/03/08
Part Number IM2146
IOPath铮?
Series Name
Manufacturer Distributed by Beckman Coulter, Inc. for
IMMUNOTECH (A Beckman Coulter Company)
130, av.de Lattre de Tassigny鈥擝P 177
13276 Marseille Cedex 09鈥擣rance T猫l. (33) 4 91 17 27 00
陇
Distributor and Refer to attached list, Document ID: 472050, for local distributor and
Emergency Phone No. emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: Meets Hazardous Criteria:
Chemical Name CAS # % by wt. EU US OSHA WHMIS
Sodium Azide 26628-22-8 0.1% T+;R28 R32 No Exempt
See Section 15 Regulatory Information for additional information on hazard classi铿乧ations.
Section 3 Hazards Identi铿乧ation
Emergency Overview
Light green.; Transparent; Liquid; Odorless
Non铿俛mmable aqueous solution.
May be harmful or fatal if swallowed.
Skin, eye and respiratory tract irritant.
Contains material of animal origin.
Physical Hazards Sodium azide forms explosive compounds with heavy metals. Repeated
contact of low concentrations of azide with lead and copper commonly found
in plumbing drains may result in the build up of shock sensitive compounds.
Potential Health May cause eye, skin and respiratory tract irritation and central nervous
Effects Summary system depression with headache, dizziness, nausea and unconsciousness.
See Section 11 Toxicological Information for more detailed health information.
Product Hazard EU: WHMIS: US OSHA:
Classi铿乧ations Xn;R22 Exempt Not applicable
Beckman Coulter Safety Flammability (Section V): 0 Code
Rating Health (Section XI): 1 0=none
Reactivity (Section X): 1 1=slight
Contact (Section VIII): 1 2=caution
3=severe
铮?2001 Beckman Coulter, Inc.
Global MSDS 鈥? English
PROGESTERONE RECEPTOR 6ml MSDS # IM2146-75 AA Page 2 of 5
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin arti铿乧ial respiration immediately and obtain medical attention.
Eye Contact If product is splashed in eyes, wash eyes under gently running water for
15 minutes or longer, making sure that the eyelids are held open. Obtain
medical attention.
Skin Contact In case of skin contact, 铿倁sh with copious amounts of water for at least 15
minutes. Remove contaminated clothing and shoes.
Ingestion If ingested, wash out mouth with water. Call a physician.
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding 铿乺e.
Special Fire and No special hazards determined.
Explosion Hazards
Hazardous Combustion Due to the composition and volume of this product, combustion products
Products generated from it are not expected to present a signi铿乧ant hazard.
Protective Equipment Self-contained breathing apparatus is recommended for 铿乺e铿乬hters.
for Fire铿乬hters
Section 6 Accidental Release Measures
Personal Precautions Use universal precautions during clean up procedures.
Spill and Leak As a precautionary measure, treat spilled material with a 1:10 bleach/water
Procedures solution. Absorb liquid and place in container suitable for disposal. Avoid
generation of aerosols during clean up. Comply with applicable waste
disposal regulations.
Environmental Contain spill to prevent migration.
Precautions
Section 7 Handling and Storage
Handling Precautions This product should be handled as though capable of transmitting infectious
diseases. Universal precautions should be followed when using this product.
Avoid inhaling, ingesting, and contact with eyes and skin.
Recommended Storage Keep away from incompatible material.
Conditions To maintain ef铿乧acy, store according to the instructions in the product
labeling.
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA: None established
PROGESTERONE RECEPTOR 6ml MSDS # IM2146-75 AA Page 3 of 5
Section 8 Exposure Controls and Personal Protection (Continued)
ACGIH:
Sodium Azide C 0.29 mg/m3 (as sodium azide)
DFG MAK:
Sodium Azide 0.2 mg/m3 MAK; in preparation
Engineering Controls Use in well ventilated area.
Respiratory Protection Under normal conditions, the use of this product should not require
respiratory protection. If overexposure should occur and ventilation is not
adequate to maintain airborne concentrations at acceptable levels, the use
of respiratory protection should be evaluated by a quali铿乪d professional.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent
skin contact.
Section 9 Physical and Chemical Properties
Physical State Liquid
Color Light green.
Transparency Transparent
Odor Odorless
Odor Threshold Not applicable
pH 7.2
Boiling Point Not available
Melting Point Not available
Speci铿乧 Gravity 1.005 @20掳C
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Solubility
Water Miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable under normal temperatures and pressures.
Hazardous Strong acids
Incompatibilities Metals and metallic compounds
Cyano compounds
Sodium azide forms explosive compounds with heavy metals. Repeated
contact of low concentrations of azide with lead and copper commonly found
in plumbing drains may result in the build up of shock sensitive compounds.
PROGESTERONE RECEPTOR 6ml MSDS # IM2146-75 AA Page 4 of 5
Section 10 Stability and Reactivity (Continued)
Hazardous When stored as labeled, no known hazardous decomposition products are
Decomposition Products formed during the shelf-life of this product.
Conditions to Avoid Keep away from incompatible material.
Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Sodium Azide Oral LD50 Rat : 27 mg/kg Oral LD50 Mouse : 27 mg/kg Dermal LD50 Rabbit
: 20 mg/kg
Primary Routes Common routes of entry include inhalation, ingestion and eye/skin contact.
of Exposure Speci铿乧 paths of concern for potentially infectious materials are skin puncture,
contact with broken skin, contact with mucous membranes and inhalation of
aerosolized material.
Potential Effects of Although its concentration in this product is low, sodium azide is highly toxic
Acute Exposure by ingestion and skin absorption. Overexposure may result in irritation of
skin, eyes and mucous membranes, lowered blood pressure and irregular
heartbeat. Sodium azide is a chemical asphyxiant and may effect the
cardiovascular, respiratory and central nervous systems. Symptoms may
include irritation, severe, pounding headaches, dizziness, weakness, nausea,
vomiting, low blood pressure, rapid heartbeat, convulsions, collapse and
death.
This product should be handled as though capable of transmitting infectious
diseases. Universal precautions should be followed when using this product.
Potential Effects of Prolonged or repeated exposure to sodium azide may result in pounding
Chronic Exposure headaches, eye and nose irritation, low blood pressure, fatigue and dizziness.
Symptoms of Symptoms of overexposure may include: eye, skin, nose and throat irritation;
Overexposure headache, weakness, dizziness, confusion, nausea and vomiting. Severe
cases may exhibit dif铿乧ulty in breathing, irregular heartbeat, reddish colored
skin, unconsciousness, convulsions, coma and death. Symptoms may be
delayed for several hours after exposure.
Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC,
NTP, OSHA or 67/548/EEC Annex I.
Other Effects Reproductive effects have been reported in animal studies.
Conditions Aggravated None identi铿乪d.
by Exposure
Section 12 Ecological Information
Ecotoxicity Toxic to 铿乻h and other water organisms.
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging
in compliance with federal, state and local regulations. If unsure of the
applicable requirements, contact the authorities for information.
Sodium azide preservative may form explosive compounds in metal drain
lines. See NIOSH Bulletin: Explosive Azide Hazard (8/16/76).
PROGESTERONE RECEPTOR 6ml MSDS # IM2146-75 AA Page 5 of 5
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IATA, US DOT, European ADR or Canadian TDG.
Section 15 Regulatory Information
US Federal and State
Regulations
SARA 313 Sodium Azide is subject to reporting requirements of Section 313, Title III of
SARA.
CERCLA RG鈥檚, Sodium Azide is listed.
40 CFR 302.4
California Proposition 65 No ingredients listed
Massachusetts MSL Sodium Azide is listed.
New Jersey Dept. of Sodium Azide is listed.
Health RTK List
Pennsylvania RTK Sodium Azide is listed.
Florida Substance List Sodium Azide is listed.
EU Labeling Classi铿乧ation
Classi铿乧ation Risk and Safety Phrases
Xn R22 Harmful if swallowed.
S28 After contact with skin, wash immediately with plenty of water.
Harmful
Canada
This product is exempt from WHMIS label and MSDS requirements.
PIN: Not applicable
Ingredients on Ingredient Sodium Azide
Disclosure List:
Ingredients with unknown Product is exempt
toxicological properties:
Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.
WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY
FOR USE OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR
REGULATIONS.
Printed in U.S.A.
|