Material Safety Data Sheet
HMIS
NFPA Personal Protective Equipment
Health Hazard
1
1 Fire Hazard
1
1 0
Reactivity
0 See Section 15.
Section 1. Chemical Product and Company Identification Page Number: 1
Catalog
Miconazole M1188
Common Name/
Number(s).
Trade Name
22916-47-8
CAS#
Manufacturer NI4770000
RTECS
SPECTRUM LABORATORY PRODUCTS INC.
14422 S. SAN PEDRO STREET TSCA 8(b) inventory: No
TSCA
products were found.
GARDENA, CA 90248
Not available.
Commercial Name(s) Not available.
CI#
1H-Imidazole,
Synonym
IN CASE OF EMERGENCY
1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-;
CHEMTREC (24hr) 800-424-9300
Imidazole,
1-(20(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-
Imidazole,1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)-
Chemical Name
Not available. CALL (310) 516-8000
Chemical Family
C18H14Cl4N2O
Chemical Formula
SPECTRUM LABORATORY PRODUCTS INC.
Supplier
14422 S. SAN PEDRO STREET
GARDENA, CA 90248
Section 2.Composition and Information on Ingredients
Exposure Limits
3
STEL (mg/m3) CEIL (mg/m3)
Name CAS # TWA (mg/m ) % by Weight
1) Miconazole 22916-47-8 100
Miconazole:
Toxicological Data
ORAL (LD50): Acute: 500 mg/kg [Rat]. 519 mg/kg [Mouse].
on Ingredients
Section 3. Hazards Identification
Potential Acute Health Effects Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation (lung irritant).
CARCINOGENIC EFFECTS: Not available.
Potential Chronic Health
MUTAGENIC EFFECTS: Not available.
Effects
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure is not known to aggravate medical condition.
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Miconazole
Section 4. First Aid Measures
Eye Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Get medical attention if irritation occurs.
Skin Contact Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Serious Skin Contact Not available.
Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention if symptoms appear.
Serious Inhalation Not available.
Ingestion Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
clothing such as a collar, tie, belt or waistband.
Serious Ingestion Not available.
Section 5. Fire and Explosion Data
May be combustible at high temperature.
Flammability of the Product
Not available.
Auto-Ignition Temperature
Not available.
Flash Points
Not available.
Flammable Limits
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.
Products of Combustion
Slightly flammable to flammable in presence of heat.
Fire Hazards in Presence of
Non-flammable in presence of shocks.
Various Substances
Explosion Hazards in Presence Slightly explosive in presence of open flames and sparks.
Non-explosive in presence of shocks.
of Various Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
and Instructions
As with most organic solids, fire is possible at elevated temperatures
Special Remarks on
Fire Hazards
Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presences of an ignition source is a potential dust
explosion hazard.
Hazards
Section 6. Accidental Release Measures
Small Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Large Spill Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water
on the contaminated surface and allow to evacuate through the sanitary system.
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Miconazole
Section 7. Handling and Storage
Keep away from heat. Keep away from sources of ignition. Do not ingest. Do not breathe dust. Wear suitable
Precautions
protective clothing. If ingested, seek medical advice immediately and show the container or the label.
Keep container tightly closed. Keep container in a cool, well-ventilated area.
Storage
Section 8. Exposure Controls/Personal Protection
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spill to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure Limits Not available.
Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Powdered solid. Crystalline powder.) Odorless.
Odor
Bitter.
Taste
416.13 g/mole
Molecular Weight
White. Off-white.
Color
Not applicable.
pH (1% soln/water)
Not available.
Boiling Point
170掳C (338掳F)
Melting Point
Not available.
Critical Temperature
Not available.
Specific Gravity
Not applicable.
Vapor Pressure
Not available.
Vapor Density
Not available.
Volatility
Not available.
Odor Threshold
Not available.
Water/Oil Dist. Coeff.
Not available.
Ionicity (in Water)
See solubility in water, acetone.
Dispersion Properties
Easily soluble in acetone.
Solubility
Insoluble in cold water, hot water.
Soluble in Dimethylformamide
Section 10. Stability and Reactivity Data
The product is stable.
Stability
Not available.
Instability Temperature
Excess heat, incompatible materials
Conditions of Instability
Not available.
Incompatibility with various
substances
Non-corrosive in presence of glass.
Corrosivity
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Miconazole
Sensitive to light.
Special Remarks on
Reactivity
Not available.
Special Remarks on
Corrosivity
Will not occur.
Polymerization
Section 11. Toxicological Information
Routes of Entry Inhalation. Ingestion.
Toxicity to Animals Acute oral toxicity (LD50): 500 mg/kg [Rat].
Chronic Effects on Humans Not available.
Other Toxic Effects on Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation (lung irritant).
Humans
Special Remarks on Not available.
Toxicity to Animals
Special Remarks on May affect genetic material (mutagenic).
Chronic Effects on Humans May cause adverse reproductive effects. based on animal test data
Special Remarks on other Acute Potential Health Effects:
Toxic Effects on Humans Skin: May cause irritation. May cause allergic (sensitivity) reactions such as itching, rash, cutaneous pruritus,
flushes
Eyes: May cause irritation.
Inhalation: May cause respiratory tract irritation.
Ingestion: May cause gastrointestinal tract irritation or upset with nausea, vomiting, diarrhea, anorexia. May
affect the cardiovascular system (tachycardia, arrhythmias), blood (aggregation of erythrocytes, anemia,
thrombocytopenia, thrombocytosis), behavior/central nervous system (drowsiness, convulsions, acute psychosis),
respiration (respiratory stimulation). It may also cause hyperlipidemia, febrile reactions, arthralgia, and anaphylxis
Section 12. Ecological Information
Not available.
Ecotoxicity
Not available.
BOD5 and COD
Possibly hazardous short term degradation products are not likely. However, long term degradation products may
Products of Biodegradation
arise.
The products of degradation are as toxic as the product itself.
Toxicity of the Products
of Biodegradation
Not available.
Special Remarks on the
Products of Biodegradation
Section 13. Disposal Considerations
Waste must be disposed of in accordance with federal, state and local environmental
Waste Disposal
control regulations.
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Miconazole
Section 14. Transport Information
DOT Classification Not a DOT controlled material (United States).
Not applicable.
Identification
Not applicable.
Special Provisions for
Transport
DOT (Pictograms)
Section 15. Other Regulatory Information and Pictograms
No products were found.
Federal and State
Regulations
California prop. 65: This product contains the following ingredients for which the State of California has found
California
to cause cancer which would require a warning under the statute: No products were found.
Proposition 65
Warnings California prop. 65: This product contains the following ingredients for which the State of California has found
to cause birth defects which would require a warning under the statute: No products were found.
Other Regulations OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
Not controlled under WHMIS (Canada).
Other Classifications WHMIS (Canada)
DSCL (EEC) R22- Harmful if swallowed. S2- Keep out of the reach of children.
S46- If swallowed, seek medical advice
immediately and show this container or label.
Health Hazard
HMIS (U.S.A.) 1 National Fire Protection Flammability
1
Association (U.S.A.)
Fire Hazard
1
0
1
Health Reactivity
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
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Miconazole
Protective Equipment Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent.
Safety glasses.
Section 16. Other Information
M4067
MSDS Code
Registry of Toxic Effects of Chemicals (RTECS).
References
-Manufacturer's Material Safety Data Sheet.
Other Special Not available.
Considerations
Validated by Sonia Owen on 8/11/2006. Verified by Sonia Owen.
Printed 9/12/2006.
CALL (310) 516-8000
Notice to Reader
All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is
combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper
methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products,
Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.
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