Material Safety Data Sheet
HMIS
NFPA Personal Protective Equipment
Health Hazard
2
3 Fire Hazard
3
2 0
Reactivity
0 See Section 15.
Section 1. Chemical Product and Company Identification Page Number: 1
Catalog
Sodium Methoxide, 0.5 M in Methanol S1600
Common Name/
Number(s).
Trade Name
Mixture.
CAS#
Manufacturer Not applicable.
RTECS
SPECTRUM LABORATORY PRODUCTS INC.
14422 S. SAN PEDRO STREET TSCA 8(b) inventory: Methyl
TSCA
alcohol; Sodium methoxide
GARDENA, CA 90248
Not available.
Commercial Name(s) Not applicable.
CI#
Sodium Methoxide (Sodium Methylate), 0.5M Solution in Methanol
Synonym
IN CASE OF EMERGENCY
Not applicable.
Chemical Name CHEMTREC (24hr) 800-424-9300
Alcohol. (Solvent.) CALL (310) 516-8000
Chemical Family
Not applicable.
Chemical Formula
SPECTRUM LABORATORY PRODUCTS INC.
Supplier
14422 S. SAN PEDRO STREET
GARDENA, CA 90248
Section 2.Composition and Information on Ingredients
Exposure Limits
3
STEL (mg/m3) CEIL (mg/m3)
Name CAS # TWA (mg/m ) % by Weight
1) Methyl alcohol 67-56-1 200 250 96.7
2) Sodium methoxide 124-41-4 15 3.3
Methyl alcohol:
Toxicological Data
ORAL (LD50): Acute: 5628 mg/kg [Rat.].
on Ingredients
DERMAL (LD50): Acute: 15800 mg/kg [Rabbit.].
VAPOR (LC50): Acute: 64000 ppm 4 hours [Rat].
Sodium methoxide:
ORAL (LD50): Acute: 2037 mg/kg [Rat].
Section 3. Hazards Identification
Potential Acute Health Effects Hazardous in case of skin contact (corrosive, irritant), of eye contact (irritant, corrosive), of ingestion, of inhalation.
Liquid or spray mist may produce tissue damage particularly on mucous membranes of eyes, mouth and
respiratory tract. Skin contact may produce burns. Inhalation of the spray mist may produce severe irritation of
respiratory tract, characterized by coughing, choking, or shortness of breath. Severe over-exposure can result in
death.
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Page Number: 2
Sodium Methoxide, 0.5 M in Methanol
Slightly hazardous in case of skin contact (sensitizer).
Potential Chronic Health
CARCINOGENIC EFFECTS: Not available.
Effects
MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. [Methyl alcohol]. Mutagenic for bacteria
and/or yeast. [Methyl alcohol].
TERATOGENIC EFFECTS: Classified POSSIBLE for human [Methyl alcohol].
DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female, Reproductive system/toxin/male
[POSSIBLE] [Methyl alcohol].
The substance may be toxic to kidneys, eyes, central nervous system (CNS).
Repeated or prolonged exposure to the substance can produce target organs damage. Repeated or prolonged
contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or prolonged
exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection.
Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in
one or many human organs.
Section 4. First Aid Measures
Eye Contact Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes,
keeping eyelids open. Cold water may be used. Get medical attention immediately.
Skin Contact In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated
clothing and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before
reuse. Thoroughly clean shoes before reuse. Get medical attention immediately.
Serious Skin Contact Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
medical attention.
Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention immediately.
Serious Inhalation Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
resuscitation. WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth resuscitation
when the inhaled material is toxic, infectious or corrosive. Seek immediate medical attention.
Ingestion If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical
attention immediately.
Serious Ingestion Not available.
Section 5. Fire and Explosion Data
Flammable.
Flammability of the Product
The lowest known value is 464掳C (867.2掳F) (Methyl alcohol).
Auto-Ignition Temperature
The lowest known value is CLOSED CUP: 12掳C (53.6掳F). OPEN CUP: 16掳C (60.8掳F). (Methyl alcohol)
Flash Points
The greatest known range is LOWER: 6% UPPER: 36.5% (Methyl alcohol)
Flammable Limits
These products are carbon oxides (CO, CO2).
Products of Combustion
Highly flammable in presence of open flames and sparks, of heat.
Fire Hazards in Presence of
Non-flammable in presence of shocks.
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
of Various Substances
Flammable liquid, soluble or dispersed in water.
Fire Fighting Media
SMALL FIRE: Use DRY chemical powder.
and Instructions
LARGE FIRE: Use alcohol foam, water spray or fog.
Explosive in the form of vapor when exposed to heat or flame. Vapor may travel considerable distance to source
Special Remarks on
of ignition and flash back. When heated to decomposition, it emits acrid smoke and irritating fumes. CAUTION:
Fire Hazards
MAY BURN WITH NEAR INVISIBLE FLAME (Methyl alcohol)
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Page Number: 3
Sodium Methoxide, 0.5 M in Methanol
Special Remarks on Explosion Forms an explosive mixture with air due to its low flash point.
Explosive when mixed with Choroform + sodium methoxide and diethyl zinc. It boils violently and explodes.
Hazards
(Methyl alcohol)
Section 6. Accidental Release Measures
Small Spill Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal
container.
Large Spill Flammable liquid. Corrosive liquid. Poisonous liquid.
Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth,
sand or other non-combustible material. Do not get water inside container. Do not touch spilled material. Use
water spray curtain to divert vapor drift. Use water spray to reduce vapors. Prevent entry into sewers,
basements or confined areas; dike if needed. Call for assistance on disposal. Be careful that the product is not
present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.
Section 7. Handling and Storage
Keep locked up.. Keep container dry. Keep away from heat. Keep away from sources of ignition. Ground all
Precautions
equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapor/spray. Never add water to this
product. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice
immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from
incompatibles such as oxidizing agents, metals, acids.
Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly
Storage
closed and sealed until ready for use. Avoid all possible sources of ignition (spark or flame).
Section 8. Exposure Controls/Personal Protection
Engineering Controls Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the
work-station location.
Personal Protection Face shield. Full suit. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Boots.
Personal Protection in Case of Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be
a Large Spill used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure Limits Methyl alcohol
TWA: 200 from OSHA (PEL) [United States]
TWA: 200 STEL: 250 (ppm) from ACGIH (TLV) [United States] [1999]
STEL: 250 from NIOSH [United States]
TWA: 200 STEL: 250 (ppm) from NIOSH SKIN
TWA: 200 STEL: 250 (ppm) [Canada]
Sodium methoxide
TWA: 10 (mg/m3) from ACGIH (TLV) [United States] Inhalation Total.
TWA: 3 (mg/m3) from ACGIH (TLV) [United States] Inhalation Respirable.
TWA: 15 (mg/m3) from OSHA (PEL) [United States] Inhalation Total.
TWA: 5 (mg/m3) from OSHA (PEL) [United States] Inhalation Respirable.
Consult local authorities for acceptable exposure limits.
Section 9. Physical and Chemical Properties
Physical state and appearance Liquid. Not available.
Odor
Not available.
Taste
Not applicable.
Molecular Weight
Clear Colorless.
Color
Not available.
pH (1% soln/water)
The lowest known value is 64.5掳C (148.1掳F) (Methyl alcohol).
Boiling Point
May start to solidify at -97.8掳C (-144掳F) based on data for: Methyl alcohol.
Melting Point
The lowest known value is 240掳C (464掳F) (Methyl alcohol).
Critical Temperature
Weighted average: 0.8 (Water = 1)
Specific Gravity
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Page Number: 4
Sodium Methoxide, 0.5 M in Methanol
The highest known value is 12.3 kPa (@ 20掳C) (Methyl alcohol).
Vapor Pressure
The highest known value is 1.11 (Air = 1) (Methyl alcohol).
Vapor Density
Not available.
Volatility
The highest known value is 100 ppm (Methyl alcohol)
Odor Threshold
Not available.
Water/Oil Dist. Coeff.
Non-ionic.
Ionicity (in Water)
See solubility in water, methanol.
Dispersion Properties
Easily soluble in hot water, methanol.
Solubility
Soluble in cold water.
Section 10. Stability and Reactivity Data
The product is stable.
Stability
Not available.
Instability Temperature
Heat, ignition sources, incompatible materials.
Conditions of Instability
Reactive with oxidizing agents, metals, acids.
Incompatibility with various
substances
Non-corrosive in presence of glass.
Corrosivity
Can react vigorously with oxidizers. Violent reaction with alkyl aluminum salts, acetyl bromide, chloroform +
Special Remarks on
sodium methoxide, chromic anhydride, cyanuirc chlorite, lead perchlorate, phosphorous trioxide, nitric acid.
Reactivity
Exothermic reaction with sodium hydroxide + chloroform.
Incompatible with beryllium dihydride, metals (potassium and magnesium), oxidants (barium perchlorate, bromine,
sodium hypochlorite, chlorine, hydrogen peroxide), potassium tert-butoxide, carbon tetrachloride, alkali metals,
metals (aluminum, potassium magnesium, zinc), and dichlormethane.
Rapid autocatalytic dissolution of aluminum, magnesium or zinc in 9:1 methanol + carbon tetrachloride -
sufficiently vigorous to be rated as potentially hazardous.
May attack some plastics, rubber, and coatings. (Methyl alcohol)
Not available.
Special Remarks on
Corrosivity
Will not occur.
Polymerization
Section 11. Toxicological Information
Routes of Entry Absorbed through skin. Eye contact. Inhalation. Ingestion.
Toxicity to Animals Acute oral toxicity (LD50): 2037 mg/kg [Rat]. (Sodium methoxide).
Acute dermal toxicity (LD50): 15800 mg/kg [Rabbit.]. (Methyl alcohol).
Chronic Effects on Humans MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. [Methyl alcohol]. Mutagenic for bacteria
and/or yeast. [Methyl alcohol].
TERATOGENIC EFFECTS: Classified POSSIBLE for human [Methyl alcohol].
DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female, Reproductive system/toxin/male
[POSSIBLE] [Methyl alcohol].
May cause damage to the following organs: kidneys, eyes, central nervous system (CNS).
Other Toxic Effects on Hazardous in case of skin contact (corrosive, irritant), of eye contact (corrosive), of ingestion, of inhalation (lung
Humans corrosive).
Special Remarks on Not available.
Toxicity to Animals
Special Remarks on Passes through the placental barrier.
Chronic Effects on Humans May affect genetic material.
May cause birth defects and adverse reproductive effects(paternal and maternal effects and fetotoxicity ) based
on animal studies. (Methyl alcohol)
Continued on Next Page
Page Number: 5
Sodium Methoxide, 0.5 M in Methanol
Special Remarks on other Acute Potential Health effects:
Toxic Effects on Humans Skin: Causes severe irritation and burns.
Eyes: Causes severe irritation and burns. May cause painful sensitization to light. May cause eye injury and
blindness.
Inhalation: May cause respiratory tract irritation. May affect behavior/central nervous system (symptoms similar
to ingestion) , gastrointestinal tract, respiration, lungs, and blood, and heart. May cause visual impairment and
possible permanent blindess.
Ingestion: May be harmful and affect eyes (cause blindness) if swallowed. May cause severe gastrointestinal
tract irritation with nausea, vomiting, diarrhea, severe abdominal pain, possible burns (corrosion of the lips,
tongue, and pharynx), and possible vomiting of large pieces of mucosa. May affect behavior/central nervous
system (CNS depression characterized by excitement followed by headache, dizziness, drowsiness, collapse,
unconciousness, coma, etc), respiration, brain, peripheral, blood, metabolism, liver, urinary system (kidneys).
Chronic Potential Health Effects:
Skin: Repeated or prolonged skin exposure may cause dermitits, an allergic reaction.
Inhalation and Ingestion: Prolonged or repeated ingestion and inhalation may cause effects similar to those of
acute inhalation and ingestion.
Section 12. Ecological Information
Not available.
Ecotoxicity
Not available.
BOD5 and COD
Possibly hazardous short term degradation products are not likely. However, long term degradation products may
Products of Biodegradation
arise.
The products of degradation are less toxic than the product itself.
Toxicity of the Products
of Biodegradation
Methanol in water is rapidly biodegraded and volatilized. Aquatic hydrolysis, oxidation, photolysis, adsorption to
Special Remarks on the
sediment, and bioconcentration are not significant fate processes. The half-life of methanol in surfact water
Products of Biodegradation
ranges from 24 hrs. to 168 hrs.
Based on its vapor pressure, methanol exists almost entirely in the vapor phase in the ambient atmosphere. It is
degraded by reaction with photochemically produced hydroxyl radicals and has an estimated half-life of 17.8 days.
Methanol is physically removed from air by rain due to its solubility. Methanol can react with NO2 in pollulted to
form methyl nitrate.
The half-life of methanol in air ranges from 71 hrs. (3 days) to 713 hrs. (29.7 days) based on photooxidation
half-life in air. (Methyl alcohol)
Section 13. Disposal Considerations
Waste must be disposed of in accordance with federal, state and local environmental
Waste Disposal
control regulations.
Section 14. Transport Information
DOT Classification CLASS 3: Flammable liquid.
Class 8: Corrosive material
: Sodium Methylate solution (Methyl alcohol) UNNA: 1289 PG: II
Identification
Not available.
Special Provisions for
Transport
DOT (Pictograms)
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Page Number: 6
Sodium Methoxide, 0.5 M in Methanol
Section 15. Other Regulatory Information and Pictograms
Connecticut hazardous material survey.: Methyl alcohol; Sodium methoxide
Federal and State
Illinois toxic substances disclosure to employee act: Methyl alcohol; Sodium methoxide
Regulations
Illinois chemical safety act: Methyl alcohol; Sodium methoxide
New York release reporting list: Methyl alcohol; Sodium methoxide
Rhode Island RTK hazardous substances: Methyl alcohol
Pennsylvania RTK: Methyl alcohol; Sodium methoxide
Minnesota: Methyl alcohol
Massachusetts RTK: Methyl alcohol; Sodium methoxide
Massachusetts spill list: Methyl alcohol; Sodium methoxide
New Jersey: Methyl alcohol; Sodium methoxide
New Jersey spill list: Methyl alcohol; Sodium methoxide
Louisiana spill reporting: Methyl alcohol; Sodium methoxide
TSCA 8(b) inventory: Methyl alcohol; Sodium methoxide
SARA 313 toxic chemical notification and release reporting: Methyl alcohol 96.7%
CERCLA: Hazardous substances.: Methyl alcohol: 5000 lbs. (2268 kg); Sodium methoxide: 1000 lbs. (453.6 kg);
California
Proposition 65
Warnings
Other Regulations OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
CLASS B-2: Flammable liquid with a flash point lower than 37.8掳C (100掳F).
Other Classifications WHMIS (Canada)
CLASS D-2A: Material causing other toxic effects (VERY TOXIC).
CLASS E: Corrosive liquid.
DSCL (EEC) R11- Highly flammable. S1/2- Keep locked up and out of the reach of
R23/25- Toxic by inhalation and if children.
swallowed. S7/8- Keep container tightly closed and dry.
R34- Causes burns. S16- Keep away from sources of ignition - No
smoking.
S24/25- Avoid contact with skin and eyes.
S26- In case of contact with eyes, rinse
immediately with plenty of water and seek
medical advice.
S37/39- Wear suitable gloves and eye/face
protection.
S45- In case of accident or if you feel unwell,
seek medical advice immediately (show the
label where possible).
S43- In case of fire, do not use water.
Health Hazard
HMIS (U.S.A.) 2 National Fire Protection Flammability
3
Association (U.S.A.)
Fire Hazard
3
0
2
Health Reactivity
Reactivity
0
Specific hazard
Personal Protection
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
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Sodium Methoxide, 0.5 M in Methanol
TDG (Canada)
(Pictograms)
3
ADR (Europe)
(Pictograms)
Protective Equipment Gloves.
Full suit.
Vapor respirator. Be sure to use an
approved/certified respirator or
equivalent. Wear appropriate respirator
when ventilation is inadequate.
Face shield.
Section 16. Other Information
S4215
MSDS Code
Not available.
References
Other Special Not available.
Considerations
Validated by Sonia Owen on 8/11/2006. Verified by Sonia Owen.
Printed 9/13/2006.
CALL (310) 516-8000
Notice to Reader
All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is
combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper
methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products,
Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.
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