**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 104-12-1 |4-Chlorophenyl isocyanate | 98 | 203-176-9 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T+
Risk Phrases: 25 26 37/38 41 42 52/53
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Toxic if swallowed. Very toxic by inhalation. Irritating to
respiratory system and skin. Risk of serious damage to eyes. May
cause sensitization by inhalation. Harmful to aquatic organisms, may
cause long-term adverse effects in the aquatic environment.Moisture
sensitive.
Potential Health Effects
Eye:
Produces irritation, characterized by a burning sensation, redness,
tearing, inflammation, and possible corneal injury. Lachrymator
(substance which increases the flow of tears). May cause
conjunctivitis, ulceration and turbidity of the cornea.
Skin:
Causes skin irritation. May cause skin sensitization, an allergic
reaction, which becomes evident upon re-exposure to this material.
May be harmful if absorbed through the skin. Organic isocyanates can
cause local irritation and allergic reactions. Isocyanates, in
general, can cause skin discoloration (staining) and hardening of the
skin after repeated exposures.
Ingestion:
Harmful if swallowed. May cause gastrointestinal irritation with
nausea, vomiting and diarrhea.
Inhalation:
Causes respiratory tract irritation. May cause allergic respiratory
reaction. At high concentrations, isocyanates affect mucous
membranes of the respiratory tract and may lead to fatal pulmonary
edema. Inhalation may cause severe irritation to the respiratory
tract with sore throat, coughing, labored breathing, and possible
pulmonary edema.
Chronic:
Chronic overexposure to isocyanates has been reported to cause lung
damage, including decreased lung fuction, which may be permanent.
Animal studies indicate that the product may affect the liver and
kidneys.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid immediately.
Skin:
In case of contact, immediately flush skin with soap and plenty of
water. Remove contaminated clothing and shoes. Get medical aid if
symptoms occur. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
POISON material. If inhaled, get medical aid immediately. Remove
victim to fresh air. If not breathing, give artificial respiration.
If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Use water
spray to keep fire-exposed containers cool. Combustible solid. Runoff
from fire control or dilution water may cause pollution. Fire or
excessive heat may result in violent rupture of the container due to
bulk polymerization. Approach fire from upwind to avoid hazardous
vapors and toxic decomposition products.
Extinguishing Media:
Do NOT get water inside containers. In case of fire, use carbon
dioxide, dry chemical powder or appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Avoid runoff into storm sewers and ditches which lead to
waterways. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Remove all sources of ignition. Provide ventilation. Do not get water
inside containers. Evacuate unnecessary personnel. Approach spill
from upwind.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Minimize dust generation and accumulation. Keep container tightly
closed. Do not allow contact with water. Wash clothing before reuse.
Discard contaminated shoes. Do not breathe dust or fumes. Keep away
from heat, sparks and flame. Do not get in eyes. Avoid contact with
skin and clothing. Inform laundry personnel of contaminant's hazards.
Isocyanates react with water to form CO2 gas. This gas can cause
sealed containers to expand and possibly rupture. Use only with
adequate ventilation or respiratory protection. Never work alone
with this chemical.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible
substances. Store in tightly closed containers to prevent moisture
contamination. Do not reseal if contamination is suspected. Store
absolutely dry.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 104-12-1:
Russia: 0.5 mg/m3 TWA
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Crystals
Color: white
Odor: sharp odor - pungent odor
pH: Not applicable.
Vapor Pressure: 0.3 mm Hg @ 20 deg C
Viscosity: Not available.
Boiling Point: 203-204 deg C @ 760 mm Hg
Freezing/Melting Point: 27-31 deg C
Autoignition Temperature: > 450 deg C (> 842.00 deg F)
Flash Point: 90 deg C ( 194.00 deg F)
Explosion Limits, lower: 2.30 vol.%
Explosion Limits, upper: 6.80 vol.%
Decomposition Temperature:
Solubility in water: Hydrolysis.
Specific Gravity/Density: 1.2600 g/cm3
Molecular Formula: C7H4ClNO
Molecular Weight: 153.57
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions. May polymerize.
Conditions to Avoid:
Ignition sources, dust generation, moisture, excess heat.
Incompatibilities with Other Materials:
Acids, alcohols, amines, strong bases, strong oxidizing agents,
water, organotin catalysts.
Hazardous Decomposition Products:
Hydrogen chloride, hydrogen cyanide, nitrogen oxides, carbon
monoxide, carbon dioxide.
Hazardous Polymerization: May occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 104-12-1: NQ8575000
LD50/LC50:
CAS# 104-12-1: Draize test, rabbit, eye: 100 mg/24H Severe; Draize
test, rabbit, skin: 20 mg/24H Moderate; Inhalation, mouse: LC50 = 53
mg/m3; Inhalation, rat: LC50 = 113 mg/m3/4H; Oral, mouse: LD50 = 450
mg/kg; Oral, rat: LD50 = 138 mg/kg.
Dermal LDLo (rabbit): 6 gm/kg.
Carcinogenicity:
4-Chlorophenyl isocyanate -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Fish: Leuciscus idus: 10 mg/l; 48H; LC50
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: ISOCYANATES, TOXIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2206
Packing Group: II
IMO
Shipping Name: ISOCYANATES, TOXIC, N.O.S.
Hazard Class: 6.1
UN Number: 2206
Packing Group: II
RID/ADR
Shipping Name: ISOCYANATES, TOXIC, N.O.S.
Hazard Class: 6.1
UN Number: 2206
Packing group: II
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+
Risk Phrases:
R 25 Toxic if swallowed.
R 26 Very toxic by inhalation.
R 37/38 Irritating to respiratory system and skin.
R 41 Risk of serious damage to eyes.
R 42 May cause sensitization by inhalation.
R 52/53 Harmful to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 104-12-1: 2
Canada
CAS# 104-12-1 is listed on Canada's NDSL List.
CAS# 104-12-1 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 104-12-1 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 12/20/1998 Revision #5 Date: 12/11/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
4-tert.-Butylbenzoic acid, 99%
| 98-73-7 |
|
Sodium bisulfite, powder, p.a.
| 7446-09-5 |
|
1,2-Dibromoethane, 99%
| 106-93-4 |
|
1,2-Dichloroethane, 99.8+% (GC)
| 107-06-2 |
|
1,2-Dichloroethane, laser grade
| 107-06-2 |
|
1,2-Dichloroethane, reagent ACS
| 107-06-2 |
|
1,2-Dichloroethane, reagent ACS, spectro grade, 99+%
| 107-06-2 |
|
HEPES, Sodium Salt, 99%
| 75277-39-3 |
|
n-Butyl Lactate, 99% (GC)
| 138-22-7 |
|
Ethylenediamine
| 107-15-3 |
|
4-Chlorophenyl isocyanate
| 104-12-1 |
|
Iron (III) Chloride, Anhydrous, 98%
| 7705-08-0 |
|
N-(2-Chloroethyl)-Morpholine Hydrochloride, 99%
| 3647-69-6 |
|
Iron(iii) chloride hexahydrate, granulated, c.p.
| 10025-77-1 |
|
Iron(iii) chloride hexahydrate, p.a.
| 10025-77-1 |
|
Iron(iii) chloride hexahydrate, reagent acs
| 10025-77-1 |
|
4-(Trifluoromethyl)Benzophenone, 97%
| 728-86-9 |
|
s-(4-Nitrobenzyl)-6-thioinosine
| 38048-32-7 |
|
2,6-Dichlorobenzyl Alcohol, 99%
| 15258-73-8 |
|
Iron(III) nitrate nonahydrate, p.a.
| 7782-61-8 |
|
Isopropyl Acetate, 99%
| 108-21-4 |
|
Iron(II) sulfate heptahydrate, p.a.
| 7720-78-7 |
|
Florisil, 100-200 mesh
| 1343-88-0 |
|
Tetramethylsilane, 99.9+% ,NMR Grade
| 75-76-3 |
|
Diphosphorus Tetraiodide, 95%
| 13455-00-0 |
|
Epichlorohydrin
| 106-89-8 |
|
Formamide, 99.5+%
| 75-12-7 |
|
Formamide, polarographic and nonaqueous, titration grade
| 75-12-7 |
|
Formamide, spectro grade
| 75-12-7 |
|
Formamide, reagent ACS
| 75-12-7 |
|
Patent blue vf, indicator grade
| 129-17-9 |
|
Acid Fuchsin, High Purity Biological Stain
| 3244-88-0 |
|
Fumaric acid, 99%
| 110-17-8 |
|
Phenyl dichlorophosphate, 99%
| 770-12-7 |
|
2-Furaldehyde, 99%
| 98-01-1 |
|
D-(+)-Galactose, 99+%
| 59-23-4 |
|
1-Tetradecanol, 99+%
| 112-72-1 |
|
Gallic Acid, Monohydrate, C.P.
| 149-91-7 |
|
Metanil yellow, 98% (TLC)
| 587-98-4 |
|
Crystal Violet, Indicator
| 548-62-9 |
|
Sodium triethylborohydride, 1M solution in tetrahydrofuran
| 109-99-9 |
|
Crystal Violet (Cert), Reagent ACS
| 548-62-9 |
|
Glycerol, 99+%
| 56-81-5 |
|
Glycerol, 83.5-88.5 Wt % Aqueous Solution
| 56-81-5 |
|
Glycerol, Reagent ACS
| 56-81-5 |
|
Glycerol, 86-88%, P.A.
| 56-81-5 |
|
Glycine, 98%
| 56-40-6 |
|
Phthalic Anhydride, 99%
| 85-44-9 |
|
Phthalic Anhydride, Reagent acs
| 85-44-9 |
|
n-Decylamine 96%
| 2016-57-1 |
|
|