**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 104-85-8 |P-Tolunitrile | 98% | 203-244-8 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XI
Risk Phrases: 36/38
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Irritating to eyes and skin.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis and
corneal damage.
Skin:
Causes skin irritation. May be metabolized to cyanide which in turn
acts by inhibiting cytochrome oxidase impairing cellular
respiration. May cause cyanosis of the extremities.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. Metabolism may release cyanide, which may result in
headache, dizziness, weakness, collapse, unconsciousness and
possible death.
Inhalation:
May cause respiratory tract irritation. Aspiration may lead to
pulmonary edema. May be metabolized to cyanide which in turns act by
inhibiting cytochrome oxidase impairing cellular respiration.
Chronic:
May be metabolized to cyanide which in turn acts by inhibiting
cytochrome oxidase impairing cellular respiration. Effects may be
delayed. Chronic exposure to cyanide solutions may lead to the
development of a "cyanide" rash, characterized by itching, and by
macular, papular, and vesicular eruptions, and may be accompanied by
secondary infections.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and
drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing
is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth
resuscitation. If breathing has ceased apply artificial respiration
using oxygen and a suitable mechanical device such as a bag and a
mask.
Notes to Physician:
Treat symptomatically and supportively. May be partially metabolized
to cyanide in the body.
Antidote:
Always have a cyanide antidote kit on hand when working with cyanide
compounds. Get medical advice to use.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Dusts at sufficient concentrations can form
explosive mixtures with air. During a fire, irritating and highly
toxic gases may be generated by thermal decomposition or combustion.
Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam. Use agent most appropriate to extinguish
fire.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Use only in a well-ventilated area.
Minimize dust generation and accumulation. Avoid contact with eyes,
skin, and clothing. Keep container tightly closed. Avoid ingestion
and inhalation. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 104-85-8:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves and clothing to
prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Solid
Color: white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 103 - 106 deg C @ 20.00mmHg
Freezing/Melting Point: 26.00 - 28.00 deg C
Autoignition Temperature: Not applicable.
Flash Point: 85 deg C ( 185.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: insoluble
Specific Gravity/Density: .9810g/cm3
Molecular Formula: C8H7N
Molecular Weight: 117.15
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong
oxidants.
Incompatibilities with Other Materials:
Oxidizing agents, strong bases.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 104-85-8: XV0700000
LD50/LC50:
CAS# 104-85-8: Draize test, rabbit, eye: 500 mg/24H Mild; Draize
test, rabbit, skin: 500 mg/24H Mild; Oral, rat: LD50 = 3800 mg/kg.
Carcinogenicity:
P-Tolunitrile -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/38 Irritating to eyes and skin.
Safety Phrases:
S 37 Wear suitable gloves.
WGK (Water Danger/Protection)
CAS# 104-85-8: 2
Canada
CAS# 104-85-8 is listed on Canada's NDSL List.
CAS# 104-85-8 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 104-85-8 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 9/02/1997 Revision #3 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
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|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
Ligroine (O3386)
| 110-54-3 |
|
Saturated Phenol, pH 6.6/7.9
| 77-86-1 |
|
Saturated Phenol, pH 4.3/4.5
| 108-95-2 |
|
Phenol/Chloroform/Isoamyl Alcohol, pH 4.3
| 67-66-3 |
|
Phenol/Chloroform/Isoamyl Alcohol (pH5.2)
| 67-66-3 |
|
Tris 1 Molar Buffer
| 77-86-1 |
|
Tris 2 Molar Buffer
| 77-86-1 |
|
4-Chloro-alpha-methylstyrene, 96% (GC)
| 1712-70-5 |
|
1,9-Diphenyl-1,3,6,8-nonatetraen-5-one, 98% (uv-vis)
| 622-21-9 |
|
4-Methoxystilbene, 98+%
| 1142-15-0 |
|
Phenoxy resin, average m.w. 85000
| 26402-79-9 |
|
2,3,5-Trimethylanisole, 99%
| 20469-61-8 |
|
4-Methoxybenzylamine, 98%
| 2393-23-9 |
|
4-Nitrophenyl phosphate tris buffer salt, 98% (titr.)
| 52435-04-8 |
|
Picrotoxin, 99%
| 124-87-8 |
|
4-Nitrocatechol, 97%
| 3316-09-4 |
|
Dipentylphthalate, 99%
| 131-18-0 |
|
Ammonium hexachlororuthenate(iv), 99%
| 18746-63-9 |
|
2-Hydroxy-5-Methoxybenzaldehyde, 98%
| 672-13-9 |
|
N-(2-acetamidophenethyl)-1-hydroxy-2-naphthamide
| 5254-41-1 |
|
Anthrone, reagent acs
| 90-44-8 |
|
(-)-cis-Myrtanylamine, 98%
| 38235-68-6 |
|
Tetrakis-(Triphenylphosphine)-Palladium(0), 99%
| 14221-01-3 |
|
N-Phenyl-p-phenylenediamine, 98%
| 101-54-2 |
|
2-Chlorophenothiazine, 97% Contains 3% Mineral Oil
| 92-39-7 |
|
n-Glycyl-l-tyrosine, hydrate, 97%
| 658-79-7 |
|
3,5-Dimethoxybenzoic Acid, 99%
| 1132-21-4 |
|
3-Chlorobenzotrifluoride, 98%
| 98-15-7 |
|
2-Bromo-4'-Phenylacetophenone, Tech.
| 135-73-9 |
|
4-tert-Butyltoluene
| 98-51-1 |
|
2,6-Diformyl-4-Methylphenol, 99%
| 7310-95-4 |
|
3-Acetoxy-2(1h)-pyridone
| 61296-14-8 |
|
N-Formylpiperidine, 99%
| 2591-86-8 |
|
1-Phenyl-1-cyclohexene, 97%
| 771-98-2 |
|
Glycine anhydride, 98%
| 106-57-0 |
|
4-Piperazinoacetophenone, 94%
| 51639-48-6 |
|
Purine, 99%
| 120-73-0 |
|
2,3-Naphthalenedicarboxylic Acid, 95%
| 2169-87-1 |
|
2-Butyl-2-Ethyl-1,3-Propanediol, 97%
| 115-84-4 |
|
4-(2-Iodoacetamido)-TEMPO, free radical
| 25713-24-0 |
|
4-Heptylbenzoyl Chloride, 99+% (Titr.)
| 50606-96-7 |
|
D-Glucosamine Hydrochloride, 98%
| 66-84-2 |
|
2-Amino-5-chlorobenzoic acid, 98%
| 634-95-7 |
|
Cyclopropyl-4-Methoxydiphenylcarbinol, 95%
| 0-00-1 |
|
6,9-Diamino-2-Ethoxyacridine Lactate, 95% (Titr.)
| 1837-57-6 |
|
2,3,5,6-Tetrabromo-4-Methylphenol, 98%
| 37721-75-8 |
|
3-Methylbenzothiazolium Iodide
| 2786-31-4 |
|
P-Tolunitrile, 98%
| 104-85-8 |
|
Trifluoromethanesulfonic Anhydride, 98%
| 358-23-6 |
|
1-Methyl-2-piperidinemethanol, 97+%
| 20845-34-5 |
|
|