**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 109-72-8 |n-Butyllithium | 12-15 | 203-698-7 |
|----------------|--------------------------------------|----------|-----------|
| 110-54-3 |Hexane | 85-88 | 203-777-6 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: F C
Risk Phrases: 11 14/15 17 34 48/20 62 51/53 65 67
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Highly flammable. Reacts violently with water liberating extremely
flammable gases. Spontaneously flammable in air. Causes burns.
Harmful : danger of serious damage to health by prolonged exposure
through inhalation. Possible risk of impaired fertility. Toxic to
aquatic organisms, may cause long-term adverse effects in the aquatic
environment. Harmful: may cause lung damage if swallowed. Vapours may
cause drowsiness and dizziness.Water-reactive.Corrosive.Hygroscopic
(absorbs moisture from the air).
Potential Health Effects
Eye:
Causes severe eye burns. May cause irreversible eye injury.
Skin:
Contact with liquid is corrosive and causes severe burns and
ulceration.
Ingestion:
Aspiration hazard. May cause central nervous system depression,
kidney damage, and liver damage. Causes digestive tract burns with
immediate pain, swelling of the throat, convulsions, and possible
coma. Aspiration of material into the lungs may cause chemical
pneumonitis, which may be fatal. May cause corrosion and permanent
tissue destruction of the esophagus and digestive tract.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. Irritation may lead to chemical pneumonitis and pulmonary
edema. Causes severe irritation of upper respiratory tract with
coughing, burns, breathing difficulty, and possible coma. May cause
effects similar to those described for ingestion.
Chronic:
Chronic inhalation and ingestion may cause effects similar to those
of acute inhalation and ingestion. Chronic exposure may cause kidney
damage.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Get medical aid immediately. Do NOT allow victim to rub eyes or keep
eyes closed. Extensive irrigation with water is required (at least 30
minutes).
Skin:
Get medical aid immediately. Flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Possible aspiration hazard. Get medical aid
immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Do NOT use mouth-to-mouth
resuscitation. If breathing has ceased apply artificial respiration
using oxygen and a suitable mechanical device such as a bag and a
mask.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
Evacuate area and fight fire from a safe distance. Containers can
build up pressure if exposed to heat and/or fire. As in any fire,
wear a self-contained breathing apparatus in pressure-demand,
MSHA/NIOSH (approved or equivalent), and full protective gear.
Vapors can travel to a source of ignition and flash back. Combustion
generates toxic fumes. Material is easily ignited if allowed to dry.
Extremely flammable. Material will readily ignite at room
temperature. Water Reactive. Material will react with water and may
release a flammable and/or toxic gas. Use water spray to keep
fire-exposed containers cool. Water may be ineffective. Material is
lighter than water and a fire may be spread by the use of water. Can
form explosive mixtures at temperatures above the flashpoint. Vapors
may be heavier than air. They can spread along the ground and
collect in low or confined areas.
Extinguishing Media:
Water may be ineffective. Do NOT use carbon dioxide. DO NOT USE
WATER! Use dry chemical. Do NOT use straight streams of water. Cool
containers with flooding quantities of water until well after fire
is out.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective
Equipment section. Scoop up with a nonsparking tool, then place into
a suitable container for disposal. Remove all sources of ignition.
Absorb spill using an absorbent, non-combustible material such as
earth, sand, or vermiculite. Do not use combustible materials such as
sawdust. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Remove contaminated clothing and wash before reuse. Ground and bond
containers when transferring material. Do not get in eyes, on skin,
or on clothing. Empty containers retain product residue, (liquid
and/or vapor), and can be dangerous. Keep container tightly closed.
Do not ingest or inhale. Do not allow contact with water. Use only in
a chemical fume hood. Store and handle protected from air. Do not use
if the material has evaporated to dryness. Do not pressurize, cut,
weld, braze, solder, drill, grind, or expose empty containers to
heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Keep container closed to prevent drying out. Keep under a
nitrogen blanket. Keep from contact with oxidizing materials. Store
in a cool, dry, well-ventilated area away from incompatible
substances. Keep away from water. Keep away from organic halogens.
Refrigerator/flammables.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local explosion-proof ventilation to keep airborne levels to
acceptable levels.
Exposure Limits
CAS# 109-72-8:
CAS# 110-54-3:
United Kingdom, WEL - TWA: 20 ppm TWA; 72 mg/m3 TWA
United Kingdom, WEL - STEL: 60 ppm STEL; 216 mg/m3 STEL
United States OSHA: 500 ppm TWA; 1800 mg/m3 TWA
Belgium - TWA: 50 ppm VLE; 179 mg/m3 VLE
France - VME: 50 ppm VME; 170 mg/m3 VME
Germany: 50 ppm TWA; 180 mg/m3 TWA
Japan: 40 ppm OEL; 140 mg/m3 OEL
Malaysia: 50 ppm TWA; 176 mg/m3 TWA
Netherlands: 25 ppm MAC; 90 mg/m3 MAC
Russia: 300 mg/m3 TWA
Spain: 50 ppm VLA-ED; 179 mg/m3 VLA-ED
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to minimize
contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Solid/Liquid Mixture
Color: clear yellow
Odor: hexane-like
pH: Not available.
Vapor Pressure: 160 mbar @ 20 deg C
Viscosity: 0.38mPas 20 deg C
Boiling Point: 60 - 80 deg C @ 760.00mm Hg
Freezing/Melting Point: -95 deg C
Autoignition Temperature: 240 deg C ( 464.00 deg F)
Flash Point: -21 deg C ( -5.80 deg F)
Explosion Limits, lower: 1.20 vol %
Explosion Limits, upper: 7.40 vol %
Decomposition Temperature:
Solubility in water: reacts
Specific Gravity/Density: .6800g/cm3
Molecular Formula: C4H9Li
Molecular Weight: 64.06
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to air, contact
with water, organic materials, strong oxidants, exposure to moist
air or water, dehydrating agents.
Incompatibilities with Other Materials:
Lithium is incompatible with acetonitrile + sulfur dioxide, bromine
pentafluoride, bromobenzene, carbon + lithium tetrachloroaluminate +
sulfunyl chloride, carbon + sulfunyl chloride, chlorine tri or
pentafluoride, diazomethane, diborane, ethylene, halocarbbons,
halogens, hydrogen, mercury, metal chlorides + nitrogen, metal
oxides and chalcogenides, metals, nitric acid, nitryly fluoride,
non-metal oxides, platinum,
pol(1,1-difluoroethylene-hexafluoropropylene) (viton), sodium
carbonate, sulfur, sulfinyl chloride, sulfur dioxide,
trifluoromethyl hypofluorite, halocarbons, halogens, iron(II)
sulfide, manganese telluride, arsenic, beryllium, maleic anhydride,
carbides, carbon dioxide, + water, chlorine, chromium, chromium
trichloride, cobalt alloys, nickel alloys, nitrogen, organic matter,
oxygen, phosphorus, rubber, silicates, sodium nitrite, tantalum (V)
oxide, vanadium, zirconium tetrachloride, iodoform, nitrogen + metal
chlorides, fluorine, magnesium perchlorate. Butyl lithium above 20%
in air can ignite spontaneously if the humidity exceeds 70%.
Concentrations above 25% are pyrophoric at any humidity. Hexane is
incompatible with dinitrogen tetraoxide.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon
dioxide, lithium hydroxide, butane, oxides of lithium.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 109-72-8 unlisted.
CAS# 110-54-3: MN9275000
LD50/LC50:
Not available.
CAS# 110-54-3: Draize test, rabbit, eye: 10 mg Mild; Inhalation,
mouse: LC50 = 150000 mg/m3/2H; Inhalation, rat: LC50 = 48000 ppm/4H;
Inhalation, rat: LC50 = 627000 mg/m3/3M; Oral, rat: LD50 = 25 gm/kg.
Carcinogenicity:
n-Butyllithium -
Not listed by ACGIH, IARC, or NTP.
Hexane -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Cas# 110-54-3:
LC50(96Hr.) Rainbow Trout = 4.14 mg/L; Flow-through
Bioassay
LC50(96Hr.)Fathead Minnow=5.10 mg/L
LC50(96Hr.)Bluegill =
4.12 mg/L
LC50 (48Hr.) Water Flea = 3.87 mg/L
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: LITHIUM ALKYLS
Hazard Class: 4.2 (4.3)
UN Number: 2445
Packing Group:
IMO
Shipping Name: LITHIUM ALKYLS
Hazard Class: 4.2 (4.3)
UN Number: 2445
Packing Group: I
RID/ADR
Shipping Name: LITHIUM ALKYLS
Hazard Class: 4.2
UN Number: 2445
Packing group: I
USA RQ: CAS# 110-54-3: 5000 lb final RQ; 2270 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F C
Risk Phrases:
R 11 Highly flammable.
R 14/15 Reacts violently with water liberating
extremely flammable gases.
R 17 Spontaneously flammable in air.
R 34 Causes burns.
R 48/20 Harmful : danger of serious damage to health
by prolonged exposure through inhalation.
R 51/53 Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
R 62 Possible risk of impaired fertility.
R 65 Harmful: may cause lung damage if swallowed.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 6A Keep under nitrogen.
S 16 Keep away from sources of ignition - No
smoking.
S 33 Take precautionary measures against static
discharges.
S 43B In case of fire, use fire-fighting equipment
on basis of sodium chloride, sodium bicarbonate (never
use water).
WGK (Water Danger/Protection)
CAS# 109-72-8: 2
CAS# 110-54-3: 1
Canada
CAS# 109-72-8 is listed on Canada's DSL List.
CAS# 110-54-3 is listed on Canada's DSL List.
CAS# 109-72-8 is not listed on Canada's Ingredient Disclosure List.
CAS# 110-54-3 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 109-72-8 is listed on the TSCA inventory.
CAS# 110-54-3 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
R 11 Highly flammable.
R 38 Irritating to skin.
R 48/20 Harmful : danger of serious damage to health by
prolonged exposure through inhalation.
R 62 Possible risk of impaired fertility.
R 51/53 Toxic to aquatic organisms, may cause long-term
adverse effects in the aquatic environment.
R 65 Harmful: may cause lung damage if swallowed.
R 67 Vapours may cause drowsiness and dizziness.
MSDS Creation Date: 6/03/1999 Revision #5 Date: 10/05/2004
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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