**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 298-46-4 |Carbamazepine | 99% | 206-062-7 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XN
Risk Phrases: 22 42/43
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful if swallowed. May cause sensitization by inhalation and skin
contact.The toxicological properties of this material have not been
fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May cause skin sensitization, an allergic
reaction, which becomes evident upon re-exposure to this material.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
May cause liver and kidney damage. The toxicological properties of
this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties
of this substance have not been fully investigated.
Chronic:
May cause liver and kidney damage. Adverse reproductive effects have
been reported in humans. Prolonged or repeated exposure may cause
sensitization in certain sensitive individuals.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and
drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing
is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth
resuscitation. If breathing has ceased apply artificial respiration
using oxygen and a suitable mechanical device such as a bag and a
mask.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid breathing dust,
vapor, mist, or gas. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 298-46-4:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Powder
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 191 - 192 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: practically insoluble in water
Specific Gravity/Density:
Molecular Formula: C15H12N2O
Molecular Weight: 236.0968
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 298-46-4: HN8225000
LD50/LC50:
CAS# 298-46-4: Oral, mouse: LD50 = 529 mg/kg; Oral, rabbit: LD50 =
2680 mg/kg; Oral, rat: LD50 = 1957 mg/kg.
Carcinogenicity:
Carbamazepine -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
R 42/43 May cause sensitization by inhalation and
skin contact.
Safety Phrases:
S 22 Do not breathe dust.
S 24 Avoid contact with skin.
S 27 Take off immediately all contaminated clothing.
WGK (Water Danger/Protection)
CAS# 298-46-4: No information available.
Canada
CAS# 298-46-4 is listed on Canada's DSL List.
CAS# 298-46-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 298-46-4 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 10/18/1999 Revision #3 Date: 5/07/2002
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
Nuclear Fast Red
| 6409-77-4 |
|
5-Sulfosalicylic acid dihydrate, p.a.
| 5965-83-3 |
|
5-Chloro-1-methyl-4-nitroimidazole
| 4897-25-0 |
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Ethyl 2-ethylacetoacetate
| 607-97-6 |
|
tert-Butyl isothiocyanate, 99% (gc)
| 590-42-1 |
|
2-(4-Chlorosulfonylphenyl)ethyltrimethoxysilane 50% solution in
| 75-09-2 |
|
Methyl 2-Chloropropionate, 96%
| 17639-93-9 |
|
Sulfur, 99.5+%, Refined
| 7704-34-9 |
|
Sulfuric Acid, 95-98%, C.P.
| 7664-93-9 |
|
3-Octylthiophene, 90%
| 65016-62-8 |
|
7-Methoxycoumarin, 98+%
| 531-59-9 |
|
L-allo-Threonine, 99%
| 28954-12-3 |
|
1-(4-Chloromethylphenyl)-2-phenylethane, 98%
| 80676-35-3 |
|
L-Tartaric Acid, Reagent ACS, 99+%
| 87-69-4 |
|
3-Chloro-4-Fluorophenol, 99%
| 2612-57-9 |
|
2-Chloro-2-methylpropane, 99%
| 507-20-0 |
|
Testosterone, 99+% (tlc)
| 58-22-0 |
|
4-(4-Ethoxyphenylazo)-M-Phenylenediamine Monohydrochloride, 98%
| 2313-87-3 |
|
Tert-Amyl Alcohol, P.A.
| 75-85-4 |
|
Sodium amide
| 7782-92-5 |
|
4-(3-Phenylpropyl)pyridine, 97%
| 2057-49-0 |
|
Tetrachloroethylene
| 127-18-4 |
|
Tetradecane
| 629-59-4 |
|
Tetraethylammonium Bromide, 99+%
| 71-91-0 |
|
Tetrahydrofuran, 99+%, Stabilized with 0.025% BHT
| 109-99-9 |
|
Ethyl 3,5-dimethyl-1H-pyrrole-2-carboxylate, 98%
| 2199-44-2 |
|
Tetrahydroxy-P-Benzoquinone, 97% (Titr.)
| 319-89-1 |
|
1,2,3,4-Tetrahydronaphthalene, 95-98%
| 119-64-2 |
|
BOC-L-Phenylalanine, 99+%
| 13734-34-4 |
|
Antimony
| 7440-36-0 |
|
Tetramethylammonium hydroxide pentahydrate
| 75-59-2 |
|
Tetramethylammonium hydroxide, 25% in water
| 75-59-2 |
|
Thallous acetate, 99% (Titr.)
| 563-68-8 |
|
D-Leucine Methyl Ester Hydrochloride, 98%
| 5845-53-4 |
|
Thiamine hydrochloride
| 67-03-8 |
|
Ethyl 2-oxo-4-phenylbutyrate, 97%
| 64920-29-2 |
|
Mercaptoacetic acid, 80% in water
| 68-11-1 |
|
2-Chloromethyl-3,5-dimethyl-4-methoxypyridine hydrochloride
| 86604-75-3 |
|
Thiourea, P.A.
| 62-56-6 |
|
Sebacoyl Chloride, 99% (titr.)
| 111-19-3 |
|
Sodium Perchlorate Monohydrate, P.A.
| 7791-07-3 |
|
2'-Aminoacetophenone, 97% (GC)
| 551-93-9 |
|
1-Naphthoxyacetic acid, 97%
| 2976-75-2 |
|
2-Amino-4,6-dimethoxpyrimidine, 98%
| 36315-01-2 |
|
Carbamazepine, 99%
| 298-46-4 |
|
R-(+)-3-Pyrrolidnol, 98%
| 2799-21-5 |
|
Trimethylene sulfide, 97%
| 287-27-4 |
|
(S)-3-Pyrrolidinol, 99%
| 100243-39-8 |
|
D-(+)-Phenyllactic Acid, 98%
| 7326-19-4 |
|
Potassium trifluoromethanesulfonate, 99%
| 2926-27-4 |
|
|