**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 4254-15-3 |Propane-1,2-diol, (S)-(+)- | 99 | unlisted |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: None Listed.
Risk Phrases: None Listed.
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Hygroscopic (absorbs moisture from the air).
Potential Health Effects
Eye:
May cause slight transient injury.
Skin:
May be absorbed through damaged or abraded skin in harmful amounts.
Allergic reactions have been reported. A single prolonged skin
exposure is not likely to result in the material being absorbed in
harmful amounts. Prolonged contact is essentially non-irritating to
skin. Repeated exposures may cause problems.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. Low hazard for usual industrial handling. May cause
hemoglobinuric nephrosis. May cause changes in surface EEG.
Inhalation:
Low hazard for usual industrial handling. May cause respiratory
tract irritation. Inhalation of a mist of this material may cause
respiratory tract irritation. Material has a low vapor pressure, so
exposure to vapor is not likely.
Chronic:
Exposure to large doses may cause central nervous system depression.
Chronic ingestion may cause lactic acidosis and possible seizures.
Exposures to propylene glycol having no adverse effects on the
mother should have no effect on the fetus. Birth defects are
unlikely. In animal studies, propylene glycol has been shown not to
interfere with reproduction.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove
contaminated clothing and shoes. Get medical aid if irritation
develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Persons with impaired kidney function may be more susceptible to the
effects of this substance. Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or alcohol-resistant
foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Provide
ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Avoid contact with
eyes, skin, and clothing. Keep container tightly closed. Avoid
ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Store
protected from moisture.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 57-55-6:
United Kingdom, WEL - TWA: 150 ppm TWA (total particulate and
vapour); 474 mg/m3 TWA (total particulate and
United Kingdom, WEL - STEL: 450 ppm STEL (total particulate and
vapour); 1422 mg/m3 STEL (total particulate
Russia: 7 mg/m3 TWA (particulates)
CAS# 4254-15-3:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: colorless viscous
Odor: Odorless
pH: Not available.
Vapor Pressure: 0.08 mm Hg @ 20 deg C
Viscosity: 0.581 cps @ 20 deg C
Boiling Point: 187 deg C @ 765 mm Hg
Freezing/Melting Point: -59 deg C
Autoignition Temperature: 371 deg C ( 699.80 deg F)
Flash Point: 99 deg C ( 210.20 deg F)
Explosion Limits, lower: 2.6 vol %
Explosion Limits, upper: 12.6 vol %
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density: 1.0360 g/cm3
Molecular Formula: C3H8O2
Molecular Weight: 76.09
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures. Hygroscopic: absorbs
moisture or water from the air.
Conditions to Avoid:
Excess heat, moist air.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, aldehydes.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 57-55-6: TY2000000
CAS# 4254-15-3 unlisted.
LD50/LC50:
CAS# 57-55-6: Draize test, rabbit, eye: 100 mg Mild; Draize test,
rabbit, eye: 500 mg/24H Mild; Oral, mouse: LD50 = 22 gm/kg; Oral,
mouse: LD50 = 20300 mg/kg; Oral, rabbit: LD50 = 18500 mg/kg; Oral,
rat: LD50 = 20 gm/kg; Skin, rabbit: LD50 = 20800 mg/kg; Skin, rabbit:
LD50 = 20800 mg/kg.
CAS# 4254-15-3.
Carcinogenicity:
1,2-propylene glycol -
Not listed by ACGIH, IARC, or NTP.
Propane-1,2-diol, (S)-(+)- -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Water flea Daphnia: EC50 > 10000 mg/L; 48 Hr; UnspecifiedBacteria:
Phytobacterium phosphoreum: EC50 = 710 mg/L; 30 min; Microtox
testFish: Goldfish: LC50 > 5000 mg/L; 24 Hr; UnspecifiedFish: Guppy:
LC50 > 1000 mg/L; 48 Hr; UnspecifiedIf released to water,
1,2-propanediol is expected to degrade relatively rapidly via
biodegradation. If released to soil, relatively rapid biodegradation
should also occur. Significant leaching in soil can be predicted.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 57-55-6: 0
CAS# 4254-15-3: No information available.
Canada
CAS# 57-55-6 is listed on Canada's DSL List.
CAS# 57-55-6 is listed on Canada's Ingredient Disclosure List.
CAS# 4254-15-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 57-55-6 is listed on the TSCA inventory.
CAS# 4254-15-3 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
MSDS Creation Date: 9/02/1997 Revision #3 Date: 12/10/2002
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
4-Butylbenzaldehyde, 98% (GC)
| 1200-14-2 |
|
Propionamide, 97%
| 79-05-0 |
|
4-Nitrobenzenesulfonamide, 97%
| 6325-93-5 |
|
1,1-Dichloroacetone, 98%
| 513-88-2 |
|
N,N-Dimethyltrimethylsilylamine, 97%
| 2083-91-2 |
|
3,6-Bis(2-Hydroxyethyl)-2,5-Diketopiperazine, 98%
| 50975-79-6 |
|
Hexacosanoic Acid, 98% (GC)
| 506-46-7 |
|
S-Benzyl-L-Cysteine, 99%
| 3054-01-1 |
|
Selenium, powder, 99.5+%, 200 mesh
| 7782-49-2 |
|
N-Ethyl-5-phenylisoxazolium-3'-sulfonate, 95%
| 4156-16-5 |
|
Zirconium(IV) chloride, anhydrous, 98%
| 10026-11-6 |
|
Ethyl Malonyl Chloride, Tech., 90+% (titr.)
| 36239-09-5 |
|
Saccharin, sodium salt hydrate, 99+%
| 82385-42-0 |
|
3,4-Dichloronitrobenzene, 95%
| 99-54-7 |
|
Aq 38s
| |
|
Allyl isothiocyanate, 94%
| 57-06-7 |
|
Phenanthrenequinone 95%
| 84-11-7 |
|
5-Fluoro-2-methylaniline, 99%
| 367-29-3 |
|
Magnesium Methyl Carbonate (1.8 M in DMF)
| 68-12-2 |
|
2-Chloro-3(Trifluoromethyl)Pyridine, 98+%
| 65753-47-1 |
|
5-Aminoindan, 96%
| 24425-40-9 |
|
R-(-)-1-Octen-3-Ol, 99%
| 3687-48-7 |
|
Germanium, Pieces, Irregular, 99.999%
| 7440-56-4 |
|
Di-Tert-Butyl Malonate
| 541-16-2 |
|
Adonitol, 99+%
| 488-81-3 |
|
Potassium perrhenate(vii), 99%
| 10466-65-6 |
|
Dl-norphenylephrine hydrochloride, 98%
| 15308-34-6 |
|
4-(4-Chlorophenyl)-4-hydroxypiperidine, 99 +%, crystalline
| 39512-49-7 |
|
1,5-Dihydroxynaphthalene, 99%
| 83-56-7 |
|
2,2-Diethoxyacetamide, 99%
| 61189-99-9 |
|
2,5-Dimethylpyrrolidine, 98%, Cis/Trans Mixture
| 3378-71-0 |
|
(S)-(+)-1,2-Propanediol, 99%
| 57-55-6 |
|
Harmane,98%
| 486-84-0 |
|
4,6-Dimethylpyrimidine, Tech., 93+%
| 1558-17-4 |
|
Diethylaluminum ethoxide, 25 wt% solution in toluene
| 108-88-3 |
|
Ethyl L-Lactate, 97% (GC)
| 687-47-8 |
|
5-Nitroisatin, 97%
| 611-09-6 |
|
3,5-Dihydroxybenzoic Acid, 97%
| 99-10-5 |
|
2-Acetylaminothiazole
| 2719-23-5 |
|
L-Tyrosine Methyl Ester, 98%
| 1080-06-4 |
|
n-Butyl propionate, 99+%
| 590-01-2 |
|
4-Methyl-3-Nitrobenzyl Chloride, 99%
| 84540-59-0 |
|
Methyl 4-Formylbenzoate Dimethyl Acetal, 95.7+% (GC)
| 42228-16-0 |
|
Ethyl palmitate, 98%
| 628-97-7 |
|
Hesperidin,97%
| 520-26-3 |
|
N,N'-bis(p-methoxybenzylidene)-alpha, alpha'-bi-p-toluidine, 99%
| 55290-05-6 |
|
6,7-Dihydroxy-3,4-Dihydroisoquinoline, 98%
| 4602-83-9 |
|
Benzoaza-15-crown-5, 99%
| 0-01-0 |
|
M-Hydroxycinnamic Acid, 99%, Predominantly Trans
| 14755-02-3 |
|
2,5-Dimethoxy-2,5-Dihydrofuran,99%,Cis/Trans Mixture
| 332-77-4 |
|
|