**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 4221-99-2 |(S)-(+)-2-Butanol | 99 | 224-168-1 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: XI
Risk Phrases: 10 36/37 67
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Flammable. Irritating to eyes and respiratory system. Vapours may
cause drowsiness and dizziness.
Potential Health Effects
Eye:
Causes eye irritation. Vapors cause eye irritation.
Skin:
Repeated or prolonged exposure may cause drying and cracking of the
skin. Brief exposures are not expected to cause skin irritation.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and
diarrhea. May cause central nervous system depression, characterized
by excitement, followed by headache, dizziness, drowsiness, and
nausea. Advanced stages may cause collapse, unconsciousness, coma
and possible death due to respiratory failure. Aspiration of material
into the lungs may cause chemical pneumonitis, which may be fatal.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. Causes respiratory tract irritation. Vapors may cause
dizziness or suffocation. May cause blood changes.
Chronic:
Prolonged or repeated skin contact may cause defatting and
dermatitis. May cause liver and kidney damage. May cause lung damage.
Animal evidence suggests that fetotoxicity and teratogenicity may be
observed at doses that also cause harmful effects in the mothers.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove
contaminated clothing and shoes. Get medical aid if irritation
develops and persists. Wash clothing before reuse.
Ingestion:
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical
personnel. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Use water
spray to keep fire-exposed containers cool. Water may be ineffective.
Material is lighter than water and a fire may be spread by the use of
water. Flammable liquid and vapor. Vapors are heavier than air and
may travel to a source of ignition and flash back. Vapors can spread
along the ground and collect in low or confined areas. This liquid
floats on water and may travel to a source of ignition and spread
fire.
Extinguishing Media:
Use water spray, alcohol foam, CO2, dry chemical.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Remove all
sources of ignition. Use a spark-proof tool. Provide ventilation. A
vapor suppressing foam may be used to reduce vapors.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Ground and bond containers when transferring
material. Use spark-proof tools and explosion proof equipment. Avoid
contact with eyes, skin, and clothing. Empty containers retain
product residue, (liquid and/or vapor), and can be dangerous. Keep
container tightly closed. Avoid ingestion and inhalation. Do not
pressurize, cut, weld, braze, solder, drill, grind, or expose empty
containers to heat, sparks or open flames. Use only with adequate
ventilation. Keep away from heat, sparks and flame. Do not allow to
evaporate to near dryness. Do not store or handle in aluminum
equipment at temperatures over 120F.
Storage:
Keep away from heat, sparks, and flame. Store in a tightly closed
container. Store in a cool, dry, well-ventilated area away from
incompatible substances. Flammables-area. Storage under a nitrogen
blanket has been recommended. Do not store in aluminum containers.
Containers should be dated when opened and tested periodically for
the presence of peroxides. All peroxidizable substances should be
stored away from heat and light and be protected from ignition
sources.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
CAS# 78-92-2:
United Kingdom, WEL - TWA: 100 ppm TWA; 308 mg/m3 TWA
United Kingdom, WEL - STEL: 150 ppm STEL; 462 mg/m3 STEL
United States OSHA: 150 ppm TWA; 450 mg/m3 TWA
Belgium - TWA: 100 ppm VLE; 307 mg/m3 VLE
France - VME: 100 ppm VME; 300 mg/m3 VME
Germany: 100 ppm TWA; 300 mg/m3 TWA
Japan: 100 ppm OEL; 300 mg/m3 OEL
Malaysia: 100 ppm TWA; 303 mg/m3 TWA
Netherlands: 150 ppm MAC; 450 mg/m3 MAC
Russia: 10 mg/m3 TWA
Spain: 100 ppm VLA-ED; 308 mg/m3 VLA-ED
CAS# 4221-99-2:
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: clear, colorless
Odor: strong odor - sweet, fruity odor
pH: Not available.
Vapor Pressure: 13 mm Hg @ 20 deg C
Viscosity: 3.5 cps @ 20 deg C
Boiling Point: 99.5 deg C @ 760 mm Hg
Freezing/Melting Point: -114 deg C
Autoignition Temperature: 405 deg C ( 761.00 deg F)
Flash Point: 24 deg C ( 75.20 deg F)
Explosion Limits, lower: 1.7% @ 100C
Explosion Limits, upper: 9.8% @ 100C
Decomposition Temperature:
Solubility in water: 12.5 g/100 ml @ 20C
Specific Gravity/Density: 0.808 g/ml
Molecular Formula: C4H10O
Molecular Weight: 74.12
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Under normal storage conditions, peroxidizable compounds can form
and accumulate peroxides which may explode when subjected to heat or
shock. This material is most hazardous when peroxide levels are
concentrated by distillation or evaporation.
Conditions to Avoid:
High temperatures, light, ignition sources.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, aluminum, organic peroxides,
isocyanates, aliphatic amines, chromium trioxide.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 78-92-2: EO1750000
CAS# 4221-99-2 unlisted.
LD50/LC50:
CAS# 78-92-2: Inhalation, rat: LC50 = 48500 mg/m3/4H; Oral, rabbit:
LD50 = 4893 mg/kg; Oral, rabbit: LD50 = 4900 mg/kg; Oral, rat: LD50
= 2193 mg/kg; Oral, rat: LD50 = 6200 mg/kg; Skin, rat: LD50 = >2
gm/kg.
CAS# 4221-99-2.
Carcinogenicity:
sec-Butyl alcohol -
Not listed by ACGIH, IARC, or NTP.
(S)-(+)-2-Butanol -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Fish: Goldfish: LC50 = 4300 mg/L; 24 Hr; UnspecifiedIf released on
soil, sec-butyl alcohol will leach into the ground. It should also
volatilize from dry soil and biodegradation will probably be the key
process affecting sec-butyl alcohol's fate in soil. If released in
water, biodegradation will probably also be the primary factor
affecting its loss.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: BUTANOLS
Hazard Class: 3
UN Number: 1120
Packing Group: III
IMO
Shipping Name: BUTANOLS
Hazard Class: 3.3
UN Number: 1120
Packing Group: III
RID/ADR
Shipping Name: BUTANOLS
Hazard Class: 3
UN Number: 1120
Packing group: III
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 10 Flammable.
R 36/37 Irritating to eyes and respiratory system.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 7/9 Keep container tightly closed and in a
well-ventilated place.
S 13 Keep away from food, drink and animal feeding
stuffs.
S 24/25 Avoid contact with skin and eyes.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 46 If swallowed, seek medical advice immediately
and show this container or label.
WGK (Water Danger/Protection)
CAS# 78-92-2: 1
CAS# 4221-99-2: No information available.
Canada
CAS# 78-92-2 is listed on Canada's DSL List.
CAS# 78-92-2 is listed on Canada's Ingredient Disclosure List.
CAS# 4221-99-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 78-92-2 is listed on the TSCA inventory.
CAS# 4221-99-2 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
MSDS Creation Date: 9/02/1997 Revision #6 Date: 3/25/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
1-Oxododecyl-beta-D-maltoside, 99+%
| 0-01-1 |
|
Ethyl methoxyacetate, 98%
| 3938-96-3 |
|
4,4-Bis(Methylthio)-2-Phenyl-But-1,3-Dien- 1,1-Dicarbonitrile, 98%
| 0-00-1 |
|
2-Ethyl-3-methylpyrazine, 99%
| 15707-23-0 |
|
2,2-Diphenylethylamine, 96%
| 3963-62-0 |
|
1,3-Dioxolane, 99%, Stab. With 50ppm BHT and 100ppm Triethylamine
| 646-06-0 |
|
3,9-Divinyl-2,4,8,10-Tetraoxaspiro 5.5 Undecane, 98%
| 78-19-3 |
|
Ammonium hexafluorotitanate(IV), 99.99%
| 16962-40-6 |
|
Trans, Trans-2,4-Heptadienal, Tech. 85-90% (GC, Total Isomers)
| 4313-03-5 |
|
Picolinic acid, 99%
| 98-98-6 |
|
2-Dodecen-1-Ylsuccinic Anhydride, Mixture of Isomers, Tech. CA 95%
| 26544-38-7 |
|
Anthracene-d10, 99+ atom % d
| 1719-06-8 |
|
3-Fluoroanisole, 99%
| 456-49-5 |
|
(S)-(+)-sec-Butanol, 99%
| 78-92-2 |
|
Acid Blue 80
| 4474-24-2 |
|
Dimethyl 3-Methyl-Trans-1,2-Cyclopropanedicarboxylate, 99%
| 28363-79-3 |
|
1-Butaneboronic acid, 99+%
| 4426-47-5 |
|
1-Methylcyclopentanol, 98%
| 1462-03-9 |
|
2-Amino-2-Methyl-1-Propanol, 99%
| 124-68-5 |
|
Yttrium(III) chloride hexahydrate
| 10025-94-2 |
|
Oxazine 4 Perchlorate, Laser Grade, 99% (UV-Vis)
| 41830-81-3 |
|
exo-2-Norbornyl formate, 99%
| 41498-71-9 |
|
Isobutyryl chloride, 98%
| 79-30-1 |
|
1,2,3-Trimethoxybenzene, 98%
| 634-36-6 |
|
Cobalt(II) chloride, anhydrous, 97%
| 7646-79-9 |
|
Benzyl-d7 chloride, 99+ atom % D
| 100-44-7 |
|
Tetrapentylammonium Chloride, 97% (Titr.)
| 4965-17-7 |
|
[tris(trimethylsilyl)]phosphine, 98%
| 15573-38-3 |
|
Quinoxaline, 99%
| 91-19-0 |
|
Tribromoacetaldehyde, 97%
| 115-17-3 |
|
Dihydro-5-phenyl-5-propyl-4,6(1h.5h)- pyrimidinedione, 99+%
| 59026-31-2 |
|
2-(Trifluoromethyl)benzyl alcohol, 97%
| 346-06-5 |
|
2,3-Dibromobutyric Acid, 98%
| 600-30-6 |
|
N-Tosylpyrrolidone
| 10019-95-1 |
|
1,2,4-Triazole, sodium derivative, tech., 90%
| 41253-21-8 |
|
1,3-Cyclopentanedione, 99%
| 3859-41-4 |
|
2-Phenylbenzothiazole, 97%
| 883-93-2 |
|
Diethylaminosulfur Trifluoride
| 38078-09-0 |
|
Chloro-dimethyl-(pentafluorophenyl)-silane , 98%
| 20082-71-7 |
|
Dicyanobis(1,10-Phenanthroline) Iron, Trihydrate, 99% (Titr.)
| 14768-11-7 |
|
(2-(1,3-Dioxan-2-yl)ethyl)triphenylphosphonium Bromide, 98%
| 69891-92-5 |
|
Diethyl 1,2-Cyclopropanedicarboxylate, 97%
| 20561-09-5 |
|
Isopropenyl chloroformate, 99% (stabilized with 50-100 ppm BHT)
| 57933-83-2 |
|
Crotonic acid, 98%
| 107-93-7 |
|
2'-(Trifluoromethyl)acetophenone, 99%
| 17408-14-9 |
|
4'-Iodoacetophenone, 98%
| 13329-40-3 |
|
Cyclooctane, 99+%
| 292-64-8 |
|
4-Bromo-2-Fluorocinnamic Acid, 97% (GC)
| 149947-19-3 |
|
Nonanoic Acid, 98+% (GC)
| 112-05-0 |
|
Selenium(iv) oxide, 99.999%
| 7446-08-4 |
|
|