**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 822-06-0 |1,6-Diisocyanatohexane | 99 + | 212-485-8 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T
Risk Phrases: 21/22 36/37/38 42/43
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful in contact with skin and if swallowed. Irritating to eyes,
respiratory system and skin. May cause sensitization by inhalation
and skin contact.Moisture sensitive.Lachrymator (substance which
increases the flow of tears).
Potential Health Effects
Eye:
Causes severe eye irritation. Lachrymator (substance which
increases the flow of tears). Vapors may cause reversible corneal
epithelial edema with impairing of vision.
Skin:
Causes severe skin irritation. Harmful if absorbed through the skin.
If absorbed, causes symptoms similar to those of ingestion.
Ingestion:
May cause irritation of the digestive tract. May cause
gastrointestinal irritation with nausea, vomiting and diarrhea. May
be harmful if swallowed.
Inhalation:
May cause asthmatic attacks due to allergic sensitization of the
respiratory tract. Causes irritation of mucous membrane. At high
concentrations, isocyanates affect mucous membranes of the
respiratory tract and may lead to fatal pulmonary edema. Exposure to
low and often even unmeasurable isocyanate concentration results in
sensitization. Symptoms of exposure include: increased secretions,
cough, pain or respiration, Symptoms of initial exposure may include
nocturnal dyspnea (labored breathing) with nocturnal cough with
progression to asthmatic bronchitis.
Chronic:
Chronic inhalation may cause effects similar to those of acute
inhalation. Repeated exposure may cause allergic respiratory reaction
(asthma). Effects may be delayed. Prolonged or repeated exposure may
cause lung irritation, chest pain, and pulmonary edema. Chronic
overexposure to isocyanates has been reported to cause lung damage,
including decreased lung fuction, which may be permanent.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid. Do
NOT allow victim to rub eyes or keep eyes closed.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and
drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively. Persons with asthma, other
respiratory disorders (bronchitis, emphysema, hyperreactivity), skin
allergies and eczema may be at increased risk from exposure to this
product. Effects may be delayed. To treat corneal damage, careful
ophthalmologic evaluation is recommended and the possibility of
local corticosteroid therapy should be considered.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Vapors may
be heavier than air. They can spread along the ground and collect
in low or confined areas. Fire or excessive heat may result in
violent rupture of the container due to bulk polymerization.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
Do NOT get water inside containers. For large fires, use water spray,
fog or alcohol-resistant foam. Do NOT use straight streams of water.
For small fires, use carbon dioxide, dry chemical, dry sand, or
alcohol-resistant foam. Most foams will react with the material and
release corrosive/toxic gases. Cool containers with flooding
quantities of water until well after fire is out.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective
Equipment section. Provide ventilation. Do not get water on spilled
substances or inside containers. Cover with dry earth, dry sand, or
other non-combustible material followed with plastic sheet to
minimize spreading and contact with water.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Do not get in
eyes, on skin, or on clothing. Keep container tightly closed. Do not
ingest or inhale. Do not allow contact with water. Keep from contact
with moist air and steam.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Keep
refrigerated. (Store below 4C/39F.) Store protected from moisture.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 822-06-0:
Belgium - TWA: 0.005 ppm VLE; 0.034 mg/m3 VLE
France - VME: 0.01 ppm VME; 0.075 mg/m3 VME
France - VLE: 0.02 ppm VLE (5 min); 0.15 mg/m3 VLE (5 min)
Germany: 0.005 ppm TWA; 0.035 mg/m3 TWA
Japan: 0.005 ppm OEL; 0.034 mg/m3 OEL
Malaysia: 0.005 ppm TWA; 0.034 mg/m3 TWA
Netherlands: 0.02 ppm STEL; 0.14 mg/m3 STEL
Netherlands: 0.005 ppm MAC; 0.04 mg/m3 MAC
Russia: 0.05 mg/m3 TWA
Spain: 0.005 ppm VLA-ED; 0.035 mg/m3 VLA-ED
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Clear liquid
Color: clear colorless to slightly yellow
Odor: sharp odor - pungent odor
pH: Not available.
Vapor Pressure: 0.05 mm Hg @ 25C
Viscosity: Not available.
Boiling Point: 255 deg C
Freezing/Melting Point: -67 deg C
Autoignition Temperature: Not applicable.
Flash Point: 140 deg C ( 284.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Reacts.
Specific Gravity/Density: 1.04
Molecular Formula: C8H12N2O2
Molecular Weight: 168.20
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions. Polymerization may occur upon heating.
Conditions to Avoid:
Incompatible materials, moisture, excess heat, temperatures above
300C.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases, alcohols, amines, heat,
moisture, water, carboxylic acids, organotin catalysts.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, irritating and
toxic fumes and gases, carbon dioxide, nitrogen.
Hazardous Polymerization: May occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 822-06-0: MO1740000
LD50/LC50:
CAS# 822-06-0: Inhalation, mouse: LC50 = 30 mg/m3; Inhalation, rat:
LC50 = 124 mg/m3/4H; Inhalation, rat: LC50 = 462 mg/m3/4H; Oral,
mouse: LD50 = 350 mg/kg; Oral, rat: LD50 = 710 uL/kg; Skin, rabbit:
LD50 = 570 uL/kg.
Carcinogenicity:
1,6-Diisocyanatohexane -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Bacteria: Phytobacterium phosphoreum: EC50 = 15.7 mg/L; 5-30 min;
Microtox test1,6-Diisocyanatohexane exists primarily in the vapor
phase and degrades by reaction with photochemically produced hydroxyl
radicals with a half-life of 2 days. Atmospheric degradation may also
occur through contact with water vapors, clouds, fog or rain. This
product reacts readily with water to form amines and polyureas. In
soil and water it will be degraded by the reaction with water.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
USA RQ: CAS# 822-06-0: 100 lb final RQ; 45.4 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 21/22 Harmful in contact with skin and if
swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 42/43 May cause sensitization by inhalation and
skin contact.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28A After contact with skin, wash immediately with
plenty of water.
S 38 In case of insufficient ventilation, wear
suitable respiratory equipment.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 822-06-0: 2
Canada
CAS# 822-06-0 is listed on Canada's DSL List.
CAS# 822-06-0 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 822-06-0 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 5/10/1999 Revision #3 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|