Material Safety Data Sheet
acc. to OSHA and ANSI
Printing date 08/19/2002 Reviewed on 03/20/2001
1 Identification of substance:
Product details:
Trade name: 2-Butyne-1,4-diol
Stock number: A14539
Manufacturer/Supplier:
Alfa Aesar, A Johnson Matthey company
Johnson Matthey Catalog Company, Inc.
30 Bond Street
Ward Hill, MA 01835-8099
Emergency Phone: (978) 521-6300
CHEMTREC: (800) 424-9300
Web Site: www.alfa.com
Information department: Health, Safety and Environmental
Department
Emergency information:
During normal hours the Health, Safety and Environmental
Department. After normal hours call Chemtrec at (800) 424-
9300.
2 Composition/Data on components:
Chemical characterization:
Description: (CAS#)
2-Butyne-1,4-diol (CAS# 110-65-6); 100%
Identification number(s):
EINECS Number: 203-788-6
EU Number: 603-076-00-9
3 Hazards identification
Hazard description:
T Toxic
F Highly flammable
Information pertaining to particular dangers for man and
environment
R 11 Highly flammable.
R 23/25 Toxic by inhalation and if swallowed.
R 34 Causes burns.
R 43 May cause sensitization by skin contact.
R 48 Danger of serious damage to health by prolonged
exposure.
4 First aid measures
General information
Immediately remove any clothing soiled by the product.
Remove breathing apparatus only after contaminated clothing
has been completely removed.
In case of irregular breathing or respiratory arrest
provide artificial respiration.
After inhalation
Supply fresh air. If required, provide artificial
respiration. Keep patient warm.
Seek immediate medical advice.
After skin contact
Immediately wash with water and soap and rinse thoroughly.
Seek immediate medical advice.
After eye contact
Rinse opened eye for several minutes under running water.
Then consult a doctor.
After swallowing
Do not induce vomiting; immediately call for medical help.
Seek immediate medical advice.
5 Fire fighting measures
Suitable extinguishing agents
Carbon dioxide, extinguishing powder or water spray. Fight
larger fires with water spray or alcohol resistant foam.
For safety reasons unsuitable extinguishing agents
Halogenated extinguisher
Special hazards caused by the material, its products of
combustion or
resulting gases:
Danger of containers bursting upon heating.
In case of fire, the following can be released:
Carbon monoxide and carbon dioxide
Protective equipment:
Wear self-contained respirator.
Wear fully protective impervious suit.
6 Accidental release measures
Person-related safety precautions:
Wear protective equipment. Keep unprotected persons away.
Ensure adequate ventilation
Keep away from ignition sources
Measures for environmental protection:
Do not allow material to be released to the environment
without proper governmental permits.
Measures for cleaning/collecting:
Use neutralizing agent.
Dispose contaminated material as waste according to item
13.
Ensure adequate ventilation.
Keep away from ignition sources.
Additional information:
See Section 7 for information on safe handling
See Section 8 for information on personal protection
equipment.
See Section 13 for disposal information.
7 Handling and storage
Handling
Information for safe handling:
Keep container tightly sealed.
Store in cool, dry place in tightly closed containers.
Ensure good ventilation at the workplace.
Open and handle container with care.
Prevent formation of dust.
Information about protection against explosions and fires:
Gases can be produced if heated in sealed containers,
causing possible rupture or explosion.
Keep ignition sources away.
Protect from heat.
Protect against electrostatic charges.
Fumes can combine with air to form an explosive mixture.
Storage
Requirements to be met by storerooms and receptacles:
Store in a cool location.
Information about storage in one common storage facility:
Protect from heat.
Do not store together with oxidizing and acidic materials.
Do not store with halide or mercury salts, or alkaline
hydroxides.
Further information about storage conditions:
Keep container tightly sealed.
Store in cool, dry conditions in well sealed containers.
Store under lock and key and with access restricted to
technical experts or their assistants only.
8 Exposure controls and personal protection
Additional information about design of technical systems:
Properly operating chemical fume hood designed for
hazardous chemicals and having an average face velocity of
at least 100 feet per minute.
Components with limit values that require monitoring at the
workplace:
Not required.
Additional information: No data
Personal protective equipment
General protective and hygienic measures
The usual precautionary measures for handling chemicals
should be followed.
Keep away from foodstuffs, beverages and feed.
Remove all soiled and contaminated clothing immediately.
Wash hands before breaks and at the end of work.
Store protective clothing separately.
Avoid contact with the eyes and skin.
Breathing equipment:
Use suitable respirator when high concentrations are
present.
Protection of hands: Impervious gloves
Eye protection:
Tightly sealed goggles
Full face protection
Body protection: Protective work clothing.
9 Physical and chemical properties:
General Information
Form:
Chips
Chunks
Color:
Yellow
Amber colored
Odor: Not determined
Value/Range Unit
Method
Change in condition
Melting point/Melting range: 54-56 掳 C
Boiling point/Boiling range: 238 掳 C
Sublimation temperature / start: Not determined
Flash point: 152 掳 C
Flammability (solid, gaseous) Powder: may cause fire
Ignition temperature: Not determined
Decomposition temperature: Not determined
Danger of explosion: Heating may cause an
explosion.
Explosion limits:
Lower: Not determined
Upper: Not determined
Vapor pressure: at 145 掳 C 20 hPa
Density: at 20 掳 C 1.2 g/cm鲁
Solubility in / Miscibility with
Water: Easily soluble
Soluble
Alcohols: Soluble
Organic solvents: Soluble in acetone.
10 Stability and reactivity
Thermal decomposition / conditions to be avoided:
Decomposition will not occur if used and stored according
to specifications.
Materials to be avoided:
Heat
Acids
Alkali metals
Oxidizing agents
Alkaline earth metals
Mercury and mercury salts
Dangerous reactions
Danger of receptacles bursting because of high vapor
pressure if heated
Can explode when reacted with halide or mercury salts and
strong acids, or alkaline hydroxides.
Dangerous products of decomposition: Carbon monoxide and
carbon dioxide
Additional information:
2-Butyne-1,4-diol is used as an intermediate, corrosion
inhibitor, electroplating brightner, defoliant,
polymerization accelerator, stabilizer for chlorinated
hydrocarbons, and as a cosolvent for paint and varnish
removal.
11 Toxicological information
Acute toxicity:
LD/LC50 values that are relevant for classification:
Oral: LD50: 75 mg/kg (bwd)
LD50: 130 mg/kg (gpg)
LD50: 105 mg/kg (mus)
LD50: 105 mg/kg (rat)
LD50: 150 mg/kg (rbt)
Inhalative: LCLo/2H: 150 mg/m3/2H (mus)
LCLo/2H: 150 mg/m3/2H (rat)
Primary irritant effect:
on the skin:
Corrosive effect on skin and mucous membranes.
Irritant to skin and mucous membranes.
on the eye:
Strong corrosive effect.
Irritating effect.
Sensitization: Sensitization possible through skin contact.
Other information (about experimental toxicology):
Reproductive effects have been observed on tests with
laboratory animals.
Subacute to chronic toxicity:
2-Butyne-1,4-diol is toxic by ingestion or inhalation
causing somnolence, blood changes such as hemorrhages,
respiratory irritation, damage, and other changes to the
lungs and trachea. Repeated ingestion may cause changes in
liver weight, white blood cell count, and blood serum
composition, with possible weight loss and enzyme
inhibition such as dehydrogenase or cholinesterase.
Prolonged exposure to fumes and dust through inhalation may
cause a drop in blood pressure, liver function impairment,
blood hemorrhages, degenerative changes to the central
nervous system section of the brain, and possible death.
Long term contact with skin may cause sensitization.
Reproductive damage, such as fetotoxicity and abnormal
musculoskeletal development, has occured through single-
dose exposures in experiments with animals. However,
reproductive effects occur at higher doses than the toxic
effects mentioned above.
Subacute to chronic toxicity:
Corrosive materials are acutely destructive to the
respiratory tract, eyes, skin and digestive tract. Eye
contact may result in permanent damage and complete vision
loss. Inhalation may result in respiratory effects such as
inflammation, edema, and chemical pneumonitis. May cause
coughing, wheezing, laryngitis, shortness of breath,
headache, nausea and vomiting. Ingestion may cause damage
to the mouth, throat and esophagus. May cause skin burns
or irritation depending on the severity of the exposure.
Additional toxicological information:
Swallowing will lead to a strong corrosive effect on mouth
and throat and to the danger of perforation of esophagus
and stomach.
To the best of our knowledge the acute and chronic toxicity
of this substance is not fully known.
No classification data on carcinogenic properties of this
material is available from the EPA, IARC, NTP, OSHA or
ACGIH.
12 Ecological information:
General notes:
Do not allow material to be released to the environment
without proper governmental permits.
13 Disposal considerations
Product:
Recommendation
Consult state, local or national regulations to ensure
proper disposal.
Uncleaned packagings:
Recommendation:
Disposal must be made according to official regulations.
Recommended cleansing agent: Water, if necessary with
cleansing agents.
14 Transport information
DOT regulations:
Hazard class: 4.1
Identification number: UN2925
Packing group: III
Proper shipping name (technical name):
Flammable solid, corrosive,
organic, n.o.s., 2-Butyne-1,4-
diol
Land transport ADR/RID (cross-border)
ADR/RID class: 4.1 Flammable solids
Item: 8c
Danger code (Kemler): 48
UN-Number: 2925
Description of goods: Flammable solid, corrosive,
organic, n.o.s.,
2-Butyne-1,4-diol
Maritime transport IMDG:
IMDG Class: 4.1
UN Number: 2925
Packaging group: III
Proper shipping name: Flammable solid, corrosive,
organic, n.o.s.,
2-Butyne-1,4-diol
Air transport ICAO-TI and IATA-DGR:
ICAO/IATA Class: 4.1
UN/ID Number: 2925
Packaging group: III
Proper shipping name: Flammable solid, corrosive,
organic, n.o.s.,
2-Butyne-1,4-diol
15 Regulations
Product related hazard informations:
Hazard symbols:
T Toxic F Highly flammable
Risk phrases:
11 Highly flammable.
23/25 Toxic by inhalation and if swallowed.
34 Causes burns.
43 May cause sensitization by skin contact.
48 Danger of serious damage to health by prolonged
exposure.
Safety phrases:
4 Keep away from living quarters.
7/9 Keep container tightly closed and in a well-
ventilated place.
20 When using do not eat or drink.
22 Do not breathe dust.
26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
36/37/39 Wear suitable protective clothing, gloves and
eye/face protection.
45 In case of accident or if you feel unwell, seek
medical advice immediately.
60 This material and its container must be disposed
of as hazardous waste.
National regulations
All components of this product are listed in the U.S.
Environmental Protection Agency Toxic Substances Control
Act Chemical Substance Inventory.
Information about limitation of use:
For use only by technically qualified individuals.
16 Other information:
Employers should use this information only as a supplement
to other information gathered by them, and should make
independent judgement of suitability of this information to
ensure proper use and protect the health and safety of
employees. This information is furnished without warranty,
and any use of the product not in conformance with this
Material Safety Data Sheet, or in combination with any
other product or process, is the responsibility of the
user.
Department issuing MSDS: Health, Safety and Environmental
Department.
Contact: Darrell R. Sanders
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