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MSDS Material Safety Data Sheet
CAS

18640-74-9
001-00-3

File Name: adv-bio_com---1386.asp
                         Material Safety Data Sheet (2001/58/EC)


1. Identification of the substance/preparation and of the company
鈥? Date of issue: May 6, 2006
鈥? Product name: 1386 2-Isobutyl thiazole Natural
鈥? Recommended use: Artificial Flavoring substance
鈥? Manufacturer: Advanced Biotech, Paterson, NJ 07524
鈥? Emergency telephone no.: 1-800-535-5053(Infotrac)
1-352-323-3500(International-call collect)

2. Composition/information on ingredients
鈥? Chemical identity: Thiazole, 2-(2-methylpropyl)
鈥? Molecular formula: C7H11NS
鈥? CAS No.: 18640-74-9
鈥? EC No.: 242-470-1
鈥? EC-Index-No.: 608-001-00-3

3. Hazards identification
Irritating to eyes, respiratory system and skin

4. First aid measures
鈥? After inhalation: Provide with fresh air
鈥? After skin contact: Take off all contaminated clothing, wash with
plenty of water
鈥? After eye contact: Rinse thoroughly with plenty of water and seek
medical advice
鈥? After swallowing: Immediately drink plenty of water; Seek
medical advice and show this container or label


5. Fire-fighting measures
鈥? Suitable extinguishing media:
Carbon Dioxide (CO2), foam, powder, water
鈥? Special protective equipment for fire fighting:
Do not stay in danger zone without self-contained breathing apparatus.
鈥? Other information:
Cool container with water spray from a safe distance. Contain escaping vapors with
water. Prevent fire-fighting water from entering surface water or groundwater. Keep
away from sources of ignition.
鈥? Special risks:
Combustible. Vapors heavier than air. Forms explosive mixtures with air at ambient
temperatures. Development of hazardous combustion gases or vapors possible in the
event of fire.

1386msds.doc Page 1 of 4
6. Accidental release measures
鈥? Person-related precautionary measures:
Do not inhale vapors/aerosols. Ensure supply of fresh air in enclosed rooms.
鈥? Environmental-protection measures:
Do not allow to enter sewage system.
鈥? Procedures for cleaning / absorption:
Take up with liquid-absorbent material. Forward for disposal. Clean affected area.

7. Handling and storage
鈥? Handling:
Take precautionary measures against static discharges. Keep away from source of
ignition. When using do not eat or drink.
鈥? Storage:
Tightly closed, in a well-ventilated place. Keep away from source of ignition - no
smoking.

8. Exposure controls and personal protection
鈥? Exposure limits
Avoid contact with eyes, skin, clothing, and breathing vapor.
鈥? Personal protective equipment:
Protective clothing should be selected specifically for the working place, depending on
concentration and quantity of the hazardous substances handled. The resistance of the
protective clothing to chemicals should be ascertained with the respective supplier.

鈥? Required when vapors/aerosols are generated.
Respiratory protection:
鈥? Wear eye/ face protection
Eye protection:
鈥? Wear suitable gloves
Hand protection:
鈥? Change contaminated clothing. Application of
Industrial hygiene:
skin-protective barrier cream recommended.
Wash hands after working with substance.

9. Physical and chemical properties:
鈥? Form: Liquid
鈥? Color: Colorless to pale yellow
鈥? Odor: Tomato leaf
鈥? pH value at 10 g/l H2O No information available
鈥? Boiling point: 172-180掳C
鈥? Flash point: 57.8潞C
鈥? Melting point: N/a
鈥? Explosive properties: No information available
鈥? Lower explosion limit: No information available
鈥? Upper explosion limit: No information available
鈥? Ignition temperature: No information available
鈥? Oxidizing properties: Not oxidizing; Not Flammable

1386msds.doc Page 2 of 4
鈥? Vapor pressure: N/a
鈥? Density/specific gravity@20潞C: 0.996-1.006
鈥? Solubility in Partly soluble
Water:
Soluble
Organic solvents:

10. Stability and reactivity
鈥? Conditions to be avoided: Heating
鈥? Substances to be avoided: Strong oxidizing agents, Nitrogen oxides,
Sulfur oxides.
鈥? Hazardous decomposition Carbon monoxide, carbon dioxide
products:
鈥? Further information: No information available

11. Toxicological information
鈥? LD50 oral, rat: No information available
鈥? LD50 dermal, rabbit: No information available
鈥? LD50 inhalation, rat: No information available
鈥? Further toxicological information: May be harmful if inhaled, swallowed, or if
absorbed through the skin.

12. Ecological information
鈥? Biologic degradation
Biodegradation: No information available
鈥? Ecotoxic effects
Biological effects: No information available
Fish toxicity: No information available
Bacterial toxicity: No information available
Daphnia toxicity: No information available
Algeal toxicity: No information available
鈥? Behavior in environmental compartments
Distribution: log P(oct): No information available
鈥? Further ecological data
Do not allow to enter water, drain or soil.

13. Disposal considerations

鈥? Product:
according to official local regulations.
鈥? Packing:
according to official local regulations.




1386msds.doc Page 3 of 4
14. Transport information

鈥? UN-no. / Name:
鈥? IMDG - Classification:
鈥? IATA - Classification: IATA
Proper Shipping Name: Flammable liquid,
n.o.s.
IATA UN Number: 1993
Hazard Class: 3
Packing Group: III
鈥? ADR - Classification:

15. Regulatory information
鈥? Labeling according to EC Directives:
Symbol: Xi Irritant
R-phrases: 36/37/38 Irritating to eyes, respiratory
system and skin

S-phrases: 26 In case of contact with eyes, rinse
immediately with plenty of water
and seek medical advice

36/37/39 Wear suitable protective clothing,
gloves and eye/face protection.
EC-no.: 242-470-1

16. Other information
鈥? The information contained herein is based on the present state of our knowledge. It
characterizes the product with regard to the appropriate safety precautions. It does not
represent a guarantee of the properties of the product.

Issued by: Advanced Biotech
85 Fifth Avenue, Building 5
Paterson, NJ 07524 - USA
Contact person: Robert S. DeSimone, Ph.D., M.B.A.




1386msds.doc Page 4 of 4

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