MESITYL OXIDE
Material Safety Data Sheet
Arkema Inc.
1 PRODUCT AND COMPANY IDENTIFICATION
EMERGENCY PHONE NUMBERS:
Thio and Fine Chemicals
Chemtrec: (800) 424-9300 (24hrs) or (703) 527-3887
Arkema Inc.
Medical: Rocky Mountain Poison Control Center
2000 Market Street
(866) 767-5089 (24Hrs)
Philadelphia, PA 19103
Information Telephone Numbers Phone Number Available Hrs
Customer Service 1-800-628-4453 8:30 to 5:30 EST
Product Name MESITYL OXIDE
Product Synonym(s)
Chemical Family Mesityl Oxide
Chemical Formula
Chemical Name 4-METHYLPENT-3-EN-2-ONE
EPA Reg Num
Product Use Synthesis intermediate
2 COMPOSITION / INFORMATION ON INGREDIENTS
Ingredient Name CAS RegistryNumber Typical Wt. % OSHA
Mesityl oxide 141-79-7 100% Y
The substance(s) marked with a "Y" in the OSHA column, are identified as hazardous chemicals according to the
criteria of the OSHA Hazard Communication Standard (29 CFR 1910.1200)
This material is classified as hazardous under Federal OSHA regulation.
The components of this product are all on the TSCA Inventory list.
3 HAZARDS IDENTIFICATION
Emergency Overview
Colorless liquid with a mint-like odor
WARNING!
FLAMMABLE LIQUID AND VAPOR.
CAUSES EYE IRRITATION.
MAY CAUSE SKIN IRRITATION.
MAY CAUSE CENTRAL NERVOUS SYSTEM EFFECTS
Potential Health Effects
Inhalation and skin contact are expected to be the primary routes of occupational exposure to this material. Based on
single exposure animal tests, it is considered to be slightly toxic if swallowed or inhaled, practically non-toxic if
absorbed through skin, severely irritating to corrosive to eyes and slightly irritating to skin. Prolonged or repeated
contact may remove oils from the skin and may dry skin and cause irritation, redness and rash. High vapor
concentrations are be irritating to the eyes and respiratory tract, and may result in central nervous system (CNS) effects
such as headache, dizziness, nausea, drowsiness and, in severe exposures, loss of consciousness. If swallowed, this
material may cause mouth and throat irritation and CNS effects as noted above.
Product Code: E0211 Page 1
Revision: 4 Issued: 28 DEC 2004 of 6
MESITYL OXIDE
Material Safety Data Sheet
Arkema Inc.
4 FIRST AID MEASURES
IF IN EYES, immediately flush with plenty of water for at least 15 minutes. Get medical attention immediately.
IF ON SKIN, immediately flush with plenty of water. Remove contaminated clothing and shoes. Get medical
attention. Wash clothing before reuse. Destroy contaminated shoes.
IF SWALLOWED, do NOT induce vomiting. Give water to drink. Get medical attention immediately. NEVER
GIVE ANYTHING BY MOUTH TO AN UNCONSCIOUS PERSON.
IF INHALED, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. Get medical attention immediately.
5 FIRE FIGHTING MEASURES
Fire and Explosive Properties
Auto-Ignition Temperature 344 C
Flash Point 28 C Flash Point Method
Flammable Limits- Upper 10.1% in volume
1.3% in volume
Lower
Extinguishing Media
Use water spray, carbon dioxide, foam or dry chemical.
Fire Fighting Instructions
Fire fighters and others who may be exposed to products of combustion should wear full fire fighting turn out
gear (full Bunker Gear) and self-contained breathing apparatus (pressure demand NIOSH approved or
equivalent). Fire fighting equipment should be thoroughly decontaminated after use.
Fire and Explosion Hazards
When burned, the following hazardous products of combustion can occur: Irritating or toxic vapors
6 ACCIDENTAL RELEASE MEASURES
In Case of Spill or Leak
Extinguish or turn off all ignition sources. Ventilate the space involved. Wear appropriate personal protection
equipment as indicated in Section 8 of this MSDS. Contain spill with inert materials. Construct a dike to
prevent spreading. Collect with non-sparking tools to a suitable container. Prevent waterway contamination.
Absorb liquid onto inert absorbent and place in DOT approved drums for disposal. Consult a regulatory
specialist to determine appropriate state or local reporting requirements, for assistance in waste
characterization and/or hazardous waste disposal and other requirements listed in pertinent environmental
permits.
7 HANDLING AND STORAGE
Handling
Do not get in eyes, on skin or clothing. Avoid breathing vapor or mist. Keep container closed. Use only with
adequate ventilation. Wash thoroughly after handling. Keep away from heat, sparks and flames. Use
grounding and bonding connection when transferring material to prevent static discharges, fire or explosion.
Storage
Store in well ventilated area away from heat and sources of ignition such as flame, sparks and static
electricity. Ensure that all storage and handling equipment is properly rated, grounded and installed to satisfy
Product Code: E0211 Page 2
Revision: 4 Issued: 28 DEC 2004 of 6
MESITYL OXIDE
Material Safety Data Sheet
Arkema Inc.
7 HANDLING AND STORAGE
electrical classification requirements. Static electricity may accumulate and create a fire hazard. All storage
containers, including containers such as drums, cylinders and IBC鈥檚, must be bonded and grounded during
filling and emptying operations. Store away from oxidizers and reactive materials. Keep container tightly
closed. Observe all federal, state and local regulations and National Fire Protection Association (NFPA)
Codes which pertain to the specific local conditions of storage and use, including OSHA 29 CFR 1910.106
and NFPA 30, 70, 77, and 497. Store out of direct sunlight in a cool, well-ventilated place. Store at
temperatures below 20 C.
8 EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering Controls
Investigate engineering techniques to reduce exposures below airborne exposure limits. Provide ventilation
if necessary to control exposure levels below airborne exposure limits (see below). If practical, use local
mechanical exhaust ventilation at sources of air contamination such as open process equipment.
Eye / Face Protection
Where there is potential for eye contact, wear chemical goggles and have eye flushing equipment available.
Skin Protection
Wear appropriate chemical resistant protective clothing and chemical resistant gloves to prevent skin
contact. Consult glove manufacturer to determine appropriate type glove material for given application.
Wear face shield and chemical resistant clothing such as a rubber apron when splashing may occur. Rinse
contaminated skin promptly. Wash contaminated clothing and clean protective equipment before reuse.
Wash skin thoroughly after handling.
Respiratory Protection
Avoid breathing vapor or mist. When airborne exposure limits are exceeded (see below), use NIOSH
approved respirator with a P 95 particulate filter. Consult respirator manufacturer if exposure levels are
greater than ten times the recommended exposure limits. Observe respirator use limitations specified by
NIOSH or the manufacturer. For emergency and other conditions where exposure limit may be significantly
exceeded, use an approved full face positive-pressure, self-contained breathing apparatus or positive-
pressure airline with auxiliary self-contained air supply. Respiratory protection programs must comply with 29
CFR 搂 1910.134.
Airborne Exposure Guidelines for Ingredients
Exposure Limit Value
Mesityl oxide
ACGIH STEL - 25 ppm
ACGIH TWA - 15 ppm
OSHA TWA PEL - 25 ppm (100 mg/m3)
-Only those components with exposure limits are printed in this section.
-Skin contact limits designated with a "Y" above have skin contact effect. Air sampling alone is insufficient to accurately quantitate
exposure. Measures to prevent significant cutaneous absorption may be required.
-ACGIH Sensitizer designator with a value of "Y" above means that exposure to this material may cause allergic reactions.
-WEEL-AIHA Sensitizer designator with a value of "Y" above means that exposure to this material may cause allergic skin reactions.
Product Code: E0211 Page 3
Revision: 4 Issued: 28 DEC 2004 of 6
MESITYL OXIDE
Material Safety Data Sheet
Arkema Inc.
9 PHYSICAL AND CHEMICAL PROPERTIES
Colorless liquid with a mint-like odor
Appearance/Odor
pH NE
Specific Gravity 0.855 (@20 C)
Vapor Pressure 1094 Pa (20 C)
Vapor Density (20 C) : 4.07 kg/m3
Melting Point -53 C
Freezing Point -53 C
Boiling Point 125 C
Solubility In Water
10 STABILITY AND REACTIVITY
Stability
This material is chemically stable under normal and anticipated storage and handling conditions.
Incompatibility
Avoid strong oxidizing agents, sodium hydroxide, amines.
Under certain conditions may form: peroxides and acids.
Hazardous Decomposition Products
Thermal decomposition giving flammable and toxic products: Peroxides
11 TOXICOLOGICAL INFORMATION
Toxicological Information
Data on this material and/or its components are summarized below.
Mesityl oxide
Acute inhalation by laboratory animals was reported to produce eye and nasal irritation, labored breathing and
narcosis. No skin allergy was observed in guinea pigs following repeated exposure. An increase in white blood
cells, liver, kidney, and spleen size were noted in rats following repeated inhalation exposure, while a decrease
in white blood cells and anemia were noted in rabbits. Repeated inhalation exposure produced decreased
growth and congestion of the liver, kidney and lung in guinea pigs and rats. A decreased pregnancy rate was
reported in rats exposed by inhalation throughout premating and mating. No developmental or adverse effects
on pregnancy were noted in rats or their offspring exposed following inhalation exposure during pregnancy. No
genetic changes were observed in tests using bacteria or animals. Mesityl oxide
Single exposure (acute) studies indicate that this material is slightly toxic if swallowed (rat LD50 655-1,120
mg/kg) or inhaled (4-hr LC50 4.5 mg/l; vapor), practically non-toxic if absorbed through skin (rabbit LD50 5,150
mg/kg), severely irritating to corrosive to rabbit eyes and slightly irritating to rabbit skin (24-hr exposure).
12 ECOLOGICAL INFORMATION
Ecotoxicological Information
Data on this material and/or its components are summarized below.
Mesityl oxide
This material is slightly toxic to fathead minnow (96-hr LC50 86 mg/l) and rainbow trout (96-hr LC50 71 mg/l). It
is practically non-toxic to goldfish (24-hr LC50 540 mg/l), Daphnia magna (48-hr EC50 110-970 mg/l) and algae
Product Code: E0211 Page 4
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MESITYL OXIDE
Material Safety Data Sheet
Arkema Inc.
12 ECOLOGICAL INFORMATION
(96-hr EC50 120 mg/l).
Chemical Fate Information
Data on this material and/or its components are summarized below.
Mesityl oxide
This material is readily biodegradable (72% after 28-days). This material has an evaporation half-life of 1.1-
days (river) to 12.2-days (pond). It has a half-life in air of 4.8-hours. It has slight adsorption in soils and
sediments (log Koc 1.18) and is practically non-bioaccumulable (log Pow 0.97).
13 DISPOSAL CONSIDERATIONS
Waste Disposal
Recover, reclaim or recycle when practical.
Disposal via incineration is recommended. Appropriate pretreatment and disposal in an authorized landfill is
acceptable. In all cases, dispose of material in accordance with all applicable federal, state, and local laws and
regulations. Consult appropriate regulatory officials or your attorney for information on such disposal.
Note: Chemical additions to, processing of, or otherwise altering this material may make this waste
management information incomplete, inaccurate, or otherwise inappropriate. Furthermore, state and local
waste disposal requirements may be more restrictive or otherwise different from federal laws and regulations.
14 TRANSPORT INFORMATION
DOT Name Mesityl Oxide
DOT Technical Name
DOT Hazard Class 3
UN Number UN 1229
DOT Packing Group PG III
RQ
15 REGULATORY INFORMATION
Hazard Categories Under Criteria of SARA Title III Rules (40 CFR Part 370)
Immediate (Acute) Health Y Fire Y
Delayed (Chronic) Health N Reactive N
Sudden Release of Pressure N
The components of this product are all on the TSCA Inventory list.
Ingredient Related Regulatory Information:
CERCLA RQ SARA TPQ
SARA Reportable Quantities
Mesityl oxide NE NE
Massachusetts Right to Know
This product does contain the following chemicals(s), as indicated below, currently on the Massachusetts Right to Know Substance
Product Code: E0211 Page 5
Revision: 4 Issued: 28 DEC 2004 of 6
MESITYL OXIDE
Material Safety Data Sheet
Arkema Inc.
Massachusetts Right to Know
This product does contain the following chemicals(s), as indicated below, currently on the Massachusetts Right to Know Substance
List.
Mesityl oxide
New Jersey Right to Know
This product does contain the following chemical(s), as indicated below, currently on the New Jersey Right-to-Know Substances List.
Mesityl oxide
Pennsylvania Right to Know
This product does contain the following chemical(s), as indicated below, currently on the Pennsylvania Hazardous Substance List.
Mesityl oxide
16 OTHER INFORMATION
Revision Information
Revision Number 4
28 DEC 2004
Revision Date
Supercedes Revision Dated 11-OCT-2004
Revision Summary
Product moved to new division
Key
NE= Not Established NA= Not Applicable (R) = Registered Trademark
Arkema Inc. believes that the information and recommendations contained herein (including data and
statements) are accurate as of the date hereof. NO WARRANTY OF FITNESS FOR ANY PARTICULAR
PURPOSE, WARRANTY OF MERCHANTABILITY, OR ANY OTHER WARRANTY, EXPRESSED OR
IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED HEREIN. The information provided
herein relates only to the specific product designated and may not be valid where such product is used in
combination with any other materials or in any process. Further, since the conditions and methods of use are
beyond the control of Arkema Inc., Arkema Inc. expressly disclaims any and all liability as to any results
obtained or arising from any use of the product or reliance on such information.
Product Code: E0211 Page 6
Revision: 4 Issued: 28 DEC 2004 of 6
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