TM
MATERIAL SAFETY DATA SHEET
1.IDENTIFICATION OF THE SUBSTANCE
Date of Preparation/Revision: 15/08/2007
Product. Asc-107 (+)-Bicuculline
Batch Number: APN07052-1-1
Ascent Scientific Ltd
Unit 68, Gazelle Rd
Weston-super-Mare
UK
Tel : +44(0)1934 624 695
Fax :+44(0)2030 700 369
Emergency phone: +44(0)7870 14 14 07
2.COMPOSITION
Substance: (R)-6-((S)-5,6,7,8-tetrahydro-6-methyl-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuro[4,5-d][1,3]dioxol-8(6H)-one
CAS No.: 485-49-4
Content : >99%
C20H17NO6
Batch Mol. Formula :
Batch Mol. Weight : 367.35
3. HAZARD IDENTIFICATION
May cause irritation to eyes, respiratory tract and skin. This product has not undergone comprehensive hazard assessment
4. FIRST AID MEASURES
Remove patients from the danger zone. Take off, remove and destroy soiled clothing and footwear immediately.
Upon inhalation: Give access to fresh air and if necessary, administer mouth-to-mouth resuscitation while protecting yourself. Keep
patient warm and seek medical advice.
After contact with eyes: Immediately rinse carefully and thoroughly with water and seek medical advice.
After contact with skin: Immediately wash with plenty of water and seek medical advice.
5.FIRE-FIGHTING MEASURES
Fight fire in early stages if safe to do so.
Extinguishing media:
sprayed water jet, water mist, foam, dry powder, CO2
In case of fire, possible formation of poisonous gases.
Wear self-sustained respirator (e.g. compressed air respirator).
6.ACCIDENTAL RELEASE MEASURES
Remove sources of ignition. Prevent material from entering drains and lower-lying rooms. Carefully sweep up residue, place in a suitable
container and dispose of this in accordance with the regulations.
Wear protective equipment breathing apparatus, rubber gloves, safety glasses & protective footwear.
7.HANDLING AND STORAGE
Use in a well ventilated room (with air inflow and outflow). Do not breath dust. Do not allow material to come into contact with eyes, skin or
clothing. Avoid extended or repeated exposure. Do not empty into drains or waters. Keep away from sources of ignition - No smoking. Keep away
from food and drink. Store in a sealed container at +4掳 or less with desiccant.
C
8.EXPOSURE CONTROLS/PERSONAL PROTECTION
Respiratory protection: Suitable respiratory equipment or breathing apparatus with separate air supply
Eye protection: Chemical safety goggles
Ascent Scientific Ltd., Unit 68, Gazelle Road, Weston-Super-Mare, Tel: +44 (0)1934 624 695 Fax: +44(0)2030 700 369
North Somerset, BS24 9ES, United Kingdom customerservice@ascentscientific.co.uk
www.ascentscientific.com
Company Registration No. 5366774 VAT No. GB 850 4220 61
TM
MATERIAL SAFETY DATA SHEET
Hand protection: Suitably compatible chemically resistant rubber gloves
Do not eat, drink or smoke at work. Wash hands before and after laboratory work.
Soiled clothing and footwear must be taken off at once and removed from room. Destroy contaminated shoes and gloves.
9.PHYSICAL AND CHEMICAL PROPERTIES
Form: Solid
Colour: Yellow
Solubility: Soluble in ethanol to 5 mM and DMSO to 100 mM
10.STABILITY AND REACTIVITY
Thermal decomposition: Material will not decompose if stored according to recommended storage conditions.
Conditions to avoid: moisture, strong oxidizing agents
Hazardous decomposition products: Carbon dioxide, carbon monoxide, nitrogen oxides
11.TOXICOLOGICAL INFORMATION
To the best of our knowledge, the chemical, physiological and toxicological effects of this material have not been fully investigated. May be
harmful in contact with the skin, eyes or respiratory tract. May cause irritation.
Exposure routes: The eyes, skin and mucous membranes are particularly at risk. Avoid contact.
Sensitisation: Unknown
12.ECOTOXICOLOGICAL INFORMATION
No data available. Do not allow to escape into waters, waste water or soil.
13.DISPOSAL CONSIDERATIONS
Consult local, state or national regulations to ensure proper disposal.
14.TRANSPORT INFORMATION
Shipping Name Alkaloid, solid, n.o.s.
IATA: UN1544, Class: 6.1, Packing Group: II
15.REGULATORY INFORMATION
Hazard Symbols: T
R-phrases 23/37/45-61 Toxic by inhalation, in contact with skin and if swallowed. Very toxic to aquatic organisms.
S-phrases
36/37-45-61 Wear suitable protective clothing and gloves. In case of accident or if you feel unwell seek medical advice
immediately (show label where possible). Avoid release to the environment. Refer to special instructions/ safety data sheets.
16.OTHER INFORMATION
Warranty: This information is believed to be correct at the time of issue of this MSDS but is not considered to be all inclusive and should
only be used as a guide. An independent assessment of the suitability of this information should be made to ensure that the
health and safety of employees is maintained.
Disclaimer: Not for drug or household use. For research and development purposes only.
Ascent Scientific Ltd., Unit 68, Gazelle Road, Weston-Super-Mare, Tel: +44 (0)1934 624 695 Fax: +44(0)2030 700 369
North Somerset, BS24 9ES, United Kingdom customerservice@ascentscientific.co.uk
www.ascentscientific.com
Company Registration No. 5366774 VAT No. GB 850 4220 61
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