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MSDS Material Safety Data Sheet
CAS

67-63-0

File Name: cellsignal_com---9002_3_ChIP_Kits_MSDS.asp
                                         Material Safety Data Sheet (MSDS) for
#9002 and #9003 SimpleChIP鈩?
Enzymatic Chromatin IP Kit New 03/08



I. IDENTIFICATION: VII. HANDLING AND STORAGE:
Storage: Store kit in tightly closed container at 4掳C.
Product name: SimpleChIP鈩? Enzymatic Chromatin IP Kit
Product Catalog Number: #9002 and #9003 XIV. TRANSPORT INFORMATION:
CAS number: None
D.O.T.
Manufacturer Supplier: Cell Signaling Technology庐
Proper Shipping Name: ISOPROPANOL (ISOPROPYL ALCOHOL), Solution
3 Trask Lane
UN Number: UN1219
Danvers, MA 01923 USA
Hazard Class: 3 Flammable liquids
1-978-867-2300 TEL
Packing Group: Packing Group II
1-978-867-2400 FAX
Hazard Label: 3
1-978-578-6737 Emergency Phone
IATA
II. COMPOSITION/INFORMATION ON INGREDIENTS: Proper Shipping Name: ISOPROPANOL (ISOPROPYL ALCOHOL), Solution
Substance Name: SimpleChIP鈩? Enzymatic Chromatin IP Kit UN Number: UN1219
ICAO/IATA Class: 3 Flammable liquids
CAS#: None
Packing Group: II
Please see the individual material safety data sheets which can be found on the CST website Hazard Label: 3
www.cellsignal.com/support/msds.html for hazard information specific to kit compo-
XV. REGULATORY INFORMATION:
nents.
US Regulations/Classifications:
鈥? Buffer A (4X) MSDS
Harmful. Flammable.
鈥? ChIP Buffer (10X) MSDS
Harmful if swallowed. Irritating to eyes and skin.
鈥? ChIP Elution Buffer (2X) MSDS
In case of contact with eyes, wash thoroughly and seek medical attention.
鈥? 0.5 M EDTA Solution MSDS
鈥? 1 M DTT MSDS SARA 313 listed: 67-63-0 propan-2-ol
鈥? DNA Binding Buffer MSDS IARC (international Agency for Research on Cancer): 67-63-0 propan-2-ol
鈥? Protease Inhibitor Cocktail MSDS
XVI. OTHER INFORMATION:
鈥? RNase A solution MSDS
鈥? Micrococcal Nuclease Solution MSDS
This product is not intended for use in humans. To the best of our knowledge, this document is
鈥? Proteinase K Solution MSDS
accurate. It is intended to serve as a guide for safe use of this product in a laboratory setting by
鈥? Histone H3 Antibody (covered by 鈥淎ntibodies鈥? MSDS)
experienced personnel. The burden of safe use of this material rests entirely with the user. The
鈥? Normal Rabbit IgG (covered by 鈥淎ntibodies鈥? MSDS)
above information is believed to be accurate but is not necessarily all-inclusive and shall be
used only as a guide. Cell Signaling Technology, Inc., shall not be held liable for any damage
III. HAZARD IDENTIFICATION:
resulting from the handling of or from contact with the above product.
Harmful. Flammable. Irritant. May cause irritation to eyes, skin, mucous membranes. Harmful
if swallowed.
HMIS Rating: Health: 3 Flammability: 3 Reactivity: 0
漏 2008 Cell Signaling Technology, Inc.




Orders n 877-616-CELL (2355) orders@cellsignal.com Support n 877-678-TECH (8324) info@cellsignal.com Web n www.cellsignal.com
Material Safety Data Sheet (MSDS) for
Buffer A (4X) New 03/08


I. IDENTIFICATION: IX. EXPOSURE CONTROLS/PERSONAL PROTECTION:
Appearance: Liquid
Product name: Buffer A (4X)
Odor: Odorless
Product Catalog Number: Component of kit #9002 and #9003
pH : Data not available
CAS number: None
Boiling Point: Data not available
Manufacturer Supplier: Cell Signaling Technology庐
Melting Point: Data not available
3 Trask Lane
Freezing Point: Data not available
Danvers, MA 01923 USA
Volatile Organic Compounds (VOC): Data not available
1-978-867-2300 TEL
Autoignition temp. Data not available
1-978-867-2400 FAX
Solubility: Soluble in water
1-978-578-6737 Emergency Phone
II. COMPOSITION/INFORMATION ON INGREDIENTS: X. STABILITY AND REACTIVITY:
According to 29 CFR 1910.1200(d), hazardous ingredients at less than <1% and carcinogens Stability: Stable.
at less than < 0.1% therefore considered non-hazardous. Any hazardous or carcinogenic Conditions to avoid: Data not available.
ingredients meeting these criteria are listed below. Hazardous Decomposition: Data not available.
Hazardous polymerization: Will not occur.
Ingredient CAS# Percent
XI. TOXICOLOGICAL INFORMATION:
Nonidet-40 9036-19-5 4%
Potassium chloride 7447-40-7 1.8% Skin Exposure: May cause skin irritation. May be harmful if absorbed through skin.
Eye Exposure: May cause eye irritation.
Dithiothreitol 3483-12-3 <1%
Inhalation: May be harmful if inhaled. Material may be irritating to mucous membrane and
Magnesium chloride 7786-30-3 <1%
upper respiratory tract.
Ingestion: May be harmful if swallowed.
III. HAZARD IDENTIFICATION: To the best of our knowledge, the chemical, physical, and toxicological properties have not
Avoid contact, ingestion, and inhalation. May be harmful if contact with skin or swallowed. been thoroughly investigated.
Irritating to eyes, respiratory system, skin.
XII. ECOLOGICAL INFORMATION:
To the best of our knowledge the chemical, physical, and toxicological properties of this buffer
have not been investigated. Data not available.
Target organ: heart.
XIII. DISPOSAL CONSIDERATIONS:
IV. FIRST AID MEASURES: Dispose of in accordance with federal, state and local environmental regulations. Contact a
licensed professional waste disposal service to dispose of this material.
Inhalation: Remove to fresh air. If breathing is difficult, get medical attention.
Ingestion: If person is conscious, wash out mouth with water. Get medical attention.
XIV. TRANSPORT INFORMATION:
Skin Exposure: Wash skin with soap and water. If irritation develops or persists, get medical
D.O.T.
attention.
Proper Shipping Name: None.
Eye Exposure: Immediately flush eyes with water for at least 15 minutes. Get medical attention.
This substance is considered non-hazardous for transport.
V. FIRE FIGHTING MEASURES: IATA
Proper Shipping Name: None.
Flash Point: Not applicable.
This substance is considered non-hazardous for air transport.
Autoignition Temperature: Not applicable.
Explosion: Not applicable.
XV. REGULATORY INFORMATION:
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
US Regulations/Classifications: May be harmful if in contact with skin or swallowed.
Firefighting: Wear protective clothing and self-contained breathing apparatus to prevent
Irritating to eyes, respiratory system, skin.
contact with skin and eyes.
In case of contact with eyes, wash thoroughly and seek medical attention.
VI. ACCIDENTAL RELEASE MEASURES:
SARA Listed: No.
Wear appropriate personal protective equipment as indicated in Section VIII. Absorb liquid with Canada (WHMIS): DSL No, NDSL No.
an absorbent material. Transfer contaminated absorbent to a closed chemical waste container
XVI. OTHER INFORMATION:
for disposal. Wash spill site after material has been picked up for disposal.
This product is not intended for use in humans. To the best of our knowledge, this document is
VII. HANDLING AND STORAGE:
accurate. It is intended to serve as a guide for safe use of this product in a laboratory setting by
Store at 4掳C in tightly closed container. experienced personnel. The burden of safe use of this material rests entirely with the user. The
Avoid prolonged or repeated exposure. Avoid contact with eyes, respiratory system, skin, and above information is believed to be accurate but is not necessarily all-inclusive and shall be
clothing. Wash thoroughly after handling. used only as a guide. Cell Signaling Technology, Inc., shall not be held liable for any damage
resulting from the handling of or from contact with the above product.
VIII. EXPOSURE CONTROLS/PERSONAL
漏 2008 Cell Signaling Technology, Inc.




Ventilation System: A system of local and general exhaust is recommended.
Skin Protection: Wear compatible chemical resistant gloves and protective clothing.
Eye protection: Wear chemical safety goggles. Maintain emergency eyewash and shower in
work area.




Orders n 877-616-CELL (2355) orders@cellsignal.com Support n 877-678-TECH (8324) info@cellsignal.com Web n www.cellsignal.com
Material Safety Data Sheet (MSDS) for
10X ChIP Buffer New 03/08


I. IDENTIFICATION: IX. EXPOSURE CONTROLS/PERSONAL PROTECTION:
Appearance: Liquid
Product name: 10X ChIP Buffer
Odor: Odorless
Product Catalog Number: Component of kit #9002 and #9003
pH: Data not available
CAS number: None
Boiling Point: Data not available
Manufacturer Supplier: Cell Signaling Technology庐
Melting Point: Data not available
3 Trask Lane
Freezing Point: Data not available
Danvers, MA 01923 USA
Volatile Organic Compounds (VOC): Data not available
1-978-867-2300 TEL
Autoignition temp. Data not available
1-978-867-2400 FAX
Solubility: Soluble in water
1-978-578-6737 Emergency Phone
II. COMPOSITION/INFORMATION ON INGREDIENTS: X. STABILITY AND REACTIVITY:
According to 29 CFR 1910.1200(d), hazardous ingredients at less than <1% and carcinogens Stability: Stable.
at less than < 0.1% therefore considered non-hazardous. Any hazardous or carcinogenic Conditions to avoid: Strong oxidizing agents, strong acids, strong bases.
ingredients meeting these criteria are listed below. Hazardous Decomposition: Carbon monoxide, carbon dioxide, sulfur oxides, sodium oxides.
Hazardous polymerization: Will not occur.
Ingredient CAS# Percent
XI. TOXICOLOGICAL INFORMATION:
Triton X-100 9002-93-1 10%
Ethylenediaminetetraacetic acid (EDTA), disodium, dihydrate 6381-92-6 1.9% Skin Exposure: May cause skin irritation. May be harmful if absorbed through skin.
Sodium dodecyl sulfate (SDS) 151-21-3 1% Eye Exposure: May cause eye irritation or severe eye burns.
Inhalation: May be harmful if inhaled. Material may be irritating to mucous membrane and
upper respiratory tract.
III. HAZARD IDENTIFICATION: Ingestion: May be harmful if swallowed.
May cause eye irritation or severe eye burns. To the best of our knowledge, the chemical, physical, and toxicological properties have not
Harmful if inhaled. May cause respiratory tract irritation. been thoroughly investigated.
Harmful if swallowed.
XII. ECOLOGICAL INFORMATION:
May be harmful if absorbed through skin. May cause skin irritation.
Data not available.
To the best of our knowledge the chemical, physical, and toxicological properties of this buffer
have not been investigated.
XIII. DISPOSAL CONSIDERATIONS:
IV. FIRST AID MEASURES: Dispose of in accordance with federal, state and local environmental regulations. Contact a
licensed professional waste disposal service to dispose of this material. Ethylenediaminetet-
Inhalation: Remove to fresh air. If breathing is difficult, get medical attention.
raacetic acid is designated as a hazardous substance under section 311(b)(2)(A) of the Federal
Ingestion: If person is conscious, wash out mouth with water. Get medical attention.
Water Pollution Control Act and further regulated by the Clean Water Act Amendments of 1977
Skin Exposure: Wash skin with soap and water. If irritation develops or persists, get medical
and 1978. These regulations apply to discharges of this substance. This designation includes
attention.
any isomers and hydrates, as well as any solutions and mixtures containing this substance.
Eye Exposure: Immediately flush eyes with water for at least 15 minutes. Get medical attention.

XIV. TRANSPORT INFORMATION:
V. FIRE FIGHTING MEASURES:
D.O.T.
Flash Point: Not applicable.
Proper Shipping Name: None.
Autoignition Temperature: Not applicable.
This substance is considered non-hazardous for transport.
Explosion: Not applicable.
IATA
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
Proper Shipping Name: None.
Firefighting: Wear protective clothing and self-contained breathing apparatus to prevent
This substance is considered non-hazardous for air transport.
contact with skin and eyes.

XV. REGULATORY INFORMATION:
VI. ACCIDENTAL RELEASE MEASURES:
US Regulations/Classifications: May be harmful if contact with skin or swallowed. Irritat-
Wear appropriate personal protective equipment as indicated in Section VIII. Absorb liquid with
ing to eyes, respiratory system, skin.
an absorbent material. Transfer contaminated absorbent to a closed chemical waste container
In case of contact with eyes, wash thoroughly and seek medical attention.
for disposal. Wash spill site after material has been picked up for disposal.
SARA Listed: No.
VII. HANDLING AND STORAGE:
Canada (WHMIS): DSL No, NDSL No.
Store at 4掳C in tightly closed container.
XVI. OTHER INFORMATION:
Avoid prolonged or repeated exposure. Avoid contact with eyes, respiratory system, skin, and
clothing. Wash thoroughly after handling.
This product is not intended for use in humans. To the best of our knowledge, this document is
accurate. It is intended to serve as a guide for safe use of this product in a laboratory setting by
VIII. EXPOSURE CONTROLS/PERSONAL
experienced personnel. The burden of safe use of this material rests entirely with the user. The
漏 2008 Cell Signaling Technology, Inc.




Ventilation System: A system of local and general exhaust is recommended. above information is believed to be accurate but is not necessarily all-inclusive and shall be
Skin Protection: Wear compatible chemical resistant gloves and protective clothing. used only as a guide. Cell Signaling Technology, Inc., shall not be held liable for any damage
Eye protection: Wear chemical safety goggles. Maintain emergency eyewash and shower in resulting from the handling of or from contact with the above product.
work area.




Orders n 877-616-CELL (2355) orders@cellsignal.com Support n 877-678-TECH (8324) info@cellsignal.com Web n www.cellsignal.com
Material Safety Data Sheet (MSDS) for
2X ChIP Elution Buffer New 03/08


I. IDENTIFICATION: IX. EXPOSURE CONTROLS/PERSONAL PROTECTION:
Appearance: Colorless liquid
Product name: 2X ChIP Elution Buffer
Odor: Odorless
Product Catalog Number: Component of kit #9002 and #9003
pH : Data not available
CAS number: None
Boiling Point: Data not available
Manufacturer Supplier: Cell Signaling Technology庐
Melting Point: Data not available
3 Trask Lane
Freezing Point: Data not available
Danvers, MA 01923 USA
Volatile Organic Compounds (VOC): Data not available
1-978-867-2300 TEL
Autoignition temp. Data not available
1-978-867-2400 FAX
Solubility: Soluble in water
1-978-578-6737 Emergency Phone
II. COMPOSITION/INFORMATION ON INGREDIENTS: X. STABILITY AND REACTIVITY:
According to 29 CFR 1910.1200(d), hazardous ingredients at less than <1% and carcinogens Stability: Stable.
at less than < 0.1% therefore considered non-hazardous. Any hazardous or carcinogenic Conditions to avoid: Strong oxidizing agents.
ingredients meeting these criteria are listed below. Hazardous Decomposition: Carbon monoxide, carbon dioxide, sulfur oxides, sodium oxides.
Hazardous polymerization: Will not occur.
Ingredient CAS# Percent
XI. TOXICOLOGICAL INFORMATION:
Ethylenediaminetetraacetic acid (EDTA), disodium, dihydrate 6381-92-6 <1%
Sodium dodecyl sulfate (SDS) 151-21-3 2% Routes of Exposure:
Skin Exposure: May cause skin irritation. May be harmful if absorbed through skin.
Eye Exposure: May cause eye irritation.
III. HAZARD IDENTIFICATION: ON HAZARDOUS INGREDIENT
Inhalation: May be harmful if inhaled. Material may be irritating to mucous membrane and
SODIUM DODECYL SULFATE upper respiratory tract.
Ingestion: May be harmful if swallowed.
Toxic. Harmful if contact with skin or swallowed. Irritating to eyes, respiratory system, skin.
Target organs: Lungs Target organ: Lungs.
To the best of our knowledge, the chemical, physical, and toxicological properties have not
HMIS Rating: Health: 2 Flammability: 0 Reactivity: 0
been thoroughly investigated.
NFPA Rating: Health: 2 Flammability: 0 Reactivity: 0
XII. ECOLOGICAL INFORMATION:
IV. FIRST AID MEASURES: Data not available.
Inhalation: Remove to fresh air. If breathing is difficult, get medical attention. XIII. DISPOSAL CONSIDERATIONS:
Ingestion: If person is conscious, wash out mouth with water. Get medical attention.
Dispose of in accordance with federal, state and local environmental regulations. Contact a
Skin Exposure: Wash skin with soap and water. If irritation develops or persists, get medical
licensed professional waste disposal service to dispose of this material.
attention.
Eye Exposure: Immediately flush eyes with water for at least 15 minutes. Get medical attention.
XIV. TRANSPORT INFORMATION:
V. FIRE FIGHTING MEASURES: D.O.T.
Proper Shipping Name: None.
Flash Point: Not applicable.
This substance is considered non-hazardous for transport.
Autoignition Temperature: Not applicable.
IATA
Explosion: Not applicable.
Proper Shipping Name: None.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
This substance is considered non-hazardous for air transport.
Firefighting: Wear protective clothing and self-contained breathing apparatus to prevent
contact with skin and eyes.
XV. REGULATORY INFORMATION:
VI. ACCIDENTAL RELEASE MEASURES: US Regulations/Classifications: Toxic. Harmful if contact with skin or swallowed. Irritating
to eyes, respiratory system, skin. In case of contact with eyes, wash thoroughly and seek
Wear appropriate personal protective equipment as indicated in Section VIII. Absorb liquid with
medical attention.
an absorbent material. Transfer contaminated absorbent to a closed chemical waste container
for disposal. Wash spill site after material has been picked up for disposal. SARA Listed: No.
VII. HANDLING AND STORAGE: Canada (WHMIS): DSL: No, NDSL: No.

XVI. OTHER INFORMATION:
Store at 4掳C in tightly closed container.
Avoid prolonged or repeated exposure. Avoid contact with eyes, respiratory system, skin, and
This product is not intended for use in humans. To the best of our knowledge, this document is
clothing. Wash thoroughly after handling.
accurate. It is intended to serve as a guide for safe use of this product in a laboratory setting by
VIII. EXPOSURE CONTROLS/PERSONAL experienced personnel. The burden of safe use of this material rests entirely with the user. The
above information is believed to be accurate but is not necessarily all-inclusive and shall be
Ventilation System: A system of local (fume hood) and general exhaust is recommended.
used only as a guide. Cell Signaling Technology, Inc., shall not be held liable for any damage
漏 2008 Cell Signaling Technology, Inc.




Skin Protection: Wear compatible chemical resistant gloves and protective clothing.
resulting from the handling of or from contact with the above product.
Eye protection: Wear chemical safety goggles. Maintain emergency eyewash and shower in
work area.




Orders n 877-616-CELL (2355) orders@cellsignal.com Support n 877-678-TECH (8324) info@cellsignal.com Web n www.cellsignal.com
Material Safety Data Sheet (MSDS) for
0.5 M EDTA New 03/08


I. IDENTIFICATION: IX. EXPOSURE CONTROLS/PERSONAL PROTECTION:
Product name: 0.5 M EDTA Solution Appearance: Colorless liquid
Product Catalog Number: Component of kit #9002 and #9003 Odor: Odorless
CAS number: None pH : Data not available
Manufacturer Supplier: Cell Signaling Technology庐 Boiling Point: Data not available
Melting Point:
3 Trask Lane Data not available
Freezing Point:
Danvers, MA 01923 USA Data not available
Volatile Organic Compounds (VOC):
1-978-867-2300 TEL Data not available
Autoignition temp.
1-978-867-2400 FAX Data not available
Solubility:
1-978-578-6737 Emergency Phone Soluble in water
II. COMPOSITION/INFORMATION ON INGREDIENTS: X. STABILITY AND REACTIVITY:
According to 29 CFR 1910.1200(d), hazardous ingredients at less than <1% and carcinogens
Stability: Stable.
at less than < 0.1% therefore considered non-hazardous. Any hazardous or carcinogenic
Conditions to avoid: Strong oxidizing agents.
ingredients meeting these criteria are listed below.
Hazardous Decomposition: Carbon monoxide, carbon dioxide, nitrogen oxides.
Hazardous polymerization: Will not occur.
Ingredient CAS# Percent
XI. TOXICOLOGICAL INFORMATION:
Ethylenediaminetetraacetic acid (EDTA), disodium, dihidrate 6381-92-6 18.6%
Skin Exposure: May cause skin irritation. May be harmful if absorbed through skin.
III. HAZARD IDENTIFICATION: Eye Exposure: May cause eye irritation.
Irritant. Irritating to eyes, respiratory system, skin. Inhalation: May be harmful if inhaled. Material may be irritating to mucous membrane and
Target organs: Central nervous system. upper respiratory tract.
Ingestion: May be harmful if swallowed.
HMIS Rating: Health: 2 Flammability: 0 Reactivity: 0
Signs and Symptoms of Exposure: To the best of our knowledge, the chemical, physical,
NFPA Rating: Health: 2 Flammability: 0 Reactivity: 0
and toxicological properties have not been thoroughly investigated.

XII. ECOLOGICAL INFORMATION:
IV. FIRST AID MEASURES:
Data not available.
Inhalation: Remove to fresh air. If breathing is difficult, get medical attention.
Ingestion: If person is conscious, wash out mouth with water. Get medical attention.
XIII. DISPOSAL CONSIDERATIONS:
Skin Exposure: Wash skin with soap and water. If irritation develops or persists, get medical
attention. Dispose of in accordance with federal, state and local environmental regulations. Contact a
Eye Exposure: Immediately flush eyes with water for at least 15 minutes. Get medical attention. licensed professional waste disposal service to dispose of this material. Ethylenediaminetet-
raacetic acid is designated as a hazardous substance under section 311(b)(2)(A) of the Federal
V. FIRE FIGHTING MEASURES: Water Pollution Control Act and further regulated by the Clean Water Act Amendments of 1977
and 1978. These regulations apply to discharges of this substance. This designation includes
Flash Point: Not applicable.
any isomers and hydrates, as well as any solutions and mixtures containing this substance.
Autoignition Temperature: Not applicable.
Explosion: Not applicable.
XIV. TRANSPORT INFORMATION:
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
Firefighting: Wear protective clothing and self-contained breathing apparatus to prevent D.O.T.
contact with skin and eyes. Proper Shipping Name: None.
This substance is considered non-hazardous for transport.
VI. ACCIDENTAL RELEASE MEASURES: IATA
Proper Shipping Name: None.
Wear appropriate personal protective equipment as indicated in Section VIII. Absorb liquid with
This substance is considered non-hazardous for air transport.
an absorbent material. Transfer contaminated absorbent to a closed chemical waste container
for disposal. Wash spill site after material has been picked up for disposal.
XV. REGULATORY INFORMATION:
VII. HANDLING AND STORAGE: EU Regulations/Classifications: Data not available.
US Regulations/Classifications:
Store at 4掳C temperature in tightly closed container.
Irritant. Irritating to eyes, respiratory system, skin.
Do not breathe vapor. Avoid contact with eyes, skin, and clothing. Wash thoroughly after
In case of contact with eyes, wash thoroughly and seek medical attention.
handling.
SARA Listed: No.
VIII. EXPOSURE CONTROLS/PERSONAL Canada (WHMIS): DSL: No, NDSL: No.
Ventilation System: A system of local and general exhaust is recommended.
XVI. OTHER INFORMATION:
Skin Protection: Wear compatible chemical resistant gloves and protective clothing.
This product is not intended for use in humans. To the best of our knowledge, this document is
Eye protection: Wear chemical safety goggles. Maintain emergency eyewash and shower in
accurate. It is intended to serve as a guide for safe use of this product in a laboratory setting by
work area.
漏 2008 Cell Signaling Technology, Inc.




experienced personnel. The burden of safe use of this material rests entirely with the user. The
above information is believed to be accurate but is not necessarily all-inclusive and shall be
used only as a guide. Cell Signaling Technology, Inc., shall not be held liable for any damage
resulting from the handling of or from contact with the above product.




Orders n 877-616-CELL (2355) orders@cellsignal.com Support n 877-678-TECH (8324) info@cellsignal.com Web n www.cellsignal.com
Material Safety Data Sheet (MSDS) for
1 M DTT New 03/08


I. IDENTIFICATION: IX. EXPOSURE CONTROLS/PERSONAL PROTECTION:
Product name: 1 M DTT Appearance: Liquid
Product Catalog Number: Component of kit #9002 and #9003 Odor: Unpleasant odor
CAS number: None pH: Data not available
Manufacturer Supplier: Cell Signaling Technology庐 Boiling Point: Data not available
Melting Point:
3 Trask Lane Data not available
Freezing Point:
Danvers, MA 01923 USA Data not available
Volatile Organic Compounds (VOC):
1-978-867-2300 TEL Data not available
Autoignition temp.
1-978-867-2400 FAX Data not available
Solubility:
1-978-578-6737 Emergency Phone Soluble in water
II. COMPOSITION/INFORMATION ON INGREDIENTS: X. STABILITY AND REACTIVITY:
According to 29 CFR 1910.1200(d), hazardous ingredients at less than <1% and carcinogens
Stability: Stable.
at less than < 0.1% therefore considered non-hazardous. Any hazardous or carcinogenic
Conditions to avoid: Bases, oxidizing agents, reducing agents, alkali metals.
ingredients meeting these criteria are listed below.
Hazardous Decomposition: Carbon monoxide, carbon dioxide, sulfur oxides, hydrogen
sulfide gas.
Ingredient CAS# Percent Hazardous polymerization: Will not occur.
Dithiothreitol 3483-12-3 15.4%
XI. TOXICOLOGICAL INFORMATION:
III. HAZARD IDENTIFICATION: Skin Exposure: Causes skin irritation. May be harmful if absorbed through skin.
Eye Exposure: Causes eye irritation.
Irritant. Irritating to eyes, respiratory system, skin.
Inhalation: May be harmful if inhaled. Material may be irritating to mucous membrane and
Target organs: Central nervous system.
upper respiratory tract.
HMIS Rating: Health: 2 Flammability: 0 Reactivity: 0 Ingestion: May be harmful if swallowed.
NFPA Rating: Health: 2 Flammability: 0 Reactivity: 0
Signs and Symptoms of Exposure: Exposure can cause CNS depression.

XII. ECOLOGICAL INFORMATION:
IV. FIRST AID MEASURES:
Data not available.
Inhalation: Remove to fresh air. If breathing is difficult, get medical attention.
Ingestion: If person is conscious, wash out mouth with water. Get medical attention.
XIII. DISPOSAL CONSIDERATIONS:
Skin Exposure: Wash skin with soap and water. If irritation develops or persists, get medical
attention. Dispose of in accordance with federal, state and local environmental regulations. Contact a
Eye Exposure: Immediately flush eyes with water for at least 15 minutes. Get medical attention. licensed professional waste disposal service to dispose of this material.
V. FIRE FIGHTING MEASURES: XIV. TRANSPORT INFORMATION:
Flash Point: Not applicable. D.O.T.
Autoignition Temperature: Not applicable. Proper Shipping Name: None.
Explosion: Not applicable. This substance is considered non-hazardous for transport.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide. IATA
Firefighting: Wear protective clothing and self-contained breathing apparatus to prevent Proper Shipping Name: None.
contact with skin and eyes. This substance is considered non-hazardous for air transport.
VI. ACCIDENTAL RELEASE MEASURES: XV. REGULATORY INFORMATION:
Wear appropriate personal protective equipment as indicated in Section VIII. Absorb liquid with EU Regulations/Classifications: Harmful. Harmful if swallowed. Irritating to eyes, respira-
an absorbent material. Transfer contaminated absorbent to a closed chemical waste container tory system, skin.
for disposal. Wash spill site after material has been picked up for disposal.
US Regulations/Classifications: Toxic. Harmful if swallowed. Irritating to eyes, respiratory
VII. HANDLING AND STORAGE: system, skin. In case of contact with eyes, wash thoroughly and seek medical attention.
SARA Listed: No.
Store at -20掳C in tightly closed container.
Canada (WHMIS): DSL: No, NDSL: No.
Do not breathe vapor. Avoid contact with eyes, skin, and clothing. Wash thoroughly after
handling.
XVI. OTHER INFORMATION:
VIII. EXPOSURE CONTROLS/PERSONAL This product is not intended for use in humans. To the best of our knowledge, this document is
accurate. It is intended to serve as a guide for safe use of this product in a laboratory setting by
Ventilation System: A system of local (fume hood) and general exhaust is recommended.
experienced personnel. The burden of safe use of this material rests entirely with the user. The
Skin Protection: Wear compatible chemical resistant gloves and protective clothing.
above information is believed to be accurate but is not necessarily all-inclusive and shall be
Eye protection: Wear chemical safety goggles. Maintain emergency eyewash and shower in
used only as a guide. Cell Signaling Technology, Inc., shall not be held liable for any damage
work area.
漏 2008 Cell Signaling Technology, Inc.




resulting from the handling of or from contact with the above product.




Orders n 877-616-CELL (2355) orders@cellsignal.com Support n 877-678-TECH (8324) info@cellsignal.com Web n www.cellsignal.com
Material Safety Data Sheet (MSDS) for
DNA Binding Buffer New 03/08


I. IDENTIFICATION: IX. EXPOSURE CONTROLS/PERSONAL PROTECTION:
Appearance: Liquid
Product name: DNA Binding Buffer
Odor: Characteristic
Product Catalog Number: Component of kit #9002 and #9003
pH at 20掳C (68掳F): 7.0
CAS number: None
Boiling Point: Data not available
Manufacturer Supplier: Cell Signaling Technology庐
Melting Point: Data not available
3 Trask Lane
Freezing Point: Data not available
Danvers, MA 01923 USA
Volatile Organic Compounds (VOC): Data not available
1-978-867-2300 TEL
Ignition temp. 425掳C (797掳F)
1-978-867-2400 FAX
Flash Point: 21-55掳C (70-131掳F)
1-978-578-6737 Emergency Phone
Autoignition: Product is not self-igniting
II. COMPOSITION/INFORMATION ON INGREDIENTS: Solubility: Soluble in water
According to 29 CFR 1910.1200(d), hazardous ingredients at less than <1% and carcinogens
X. STABILITY AND REACTIVITY:
at less than < 0.1% therefore considered non-hazardous. Any hazardous or carcinogenic
ingredients meeting these criteria are listed below. Stability: Stable.
Conditions to avoid: Acids, alkalis, oxidizing reagents.
Ingredient CAS# Percent Hazardous Decomposition: Data not available.
Guanidinium chloride 50-01-1 25-50% Hazardous polymerization: Data not available.
Propan-2-ol 67-63-0 25-50%
XI. TOXICOLOGICAL INFORMATION:
III. HAZARD IDENTIFICATION:
Skin Exposure: Causes skin irritation. May be harmful if absorbed through skin.
Harmful. Flammable. Harmful if swallowed. Irritating to eyes, skin. Eye Exposure: Causes eye irritation.
Inhalation: Harmful if inhaled. Causes irritation to mucous membrane and upper
HMIS Rating: Health: 3 Flammability: 3 Reactivity: 0
respiratory tract.
NFPA Rating: Health: 3 Flammability: 3 Reactivity: 0
Ingestion: Harmful if swallowed.
To the best of our knowledge, the chemical, physical, and toxicological properties have not
IV. FIRST AID MEASURES: been thoroughly investigated.
Inhalation: Remove to fresh air. If breathing is difficult, get medical attention.
XII. ECOLOGICAL INFORMATION:
Ingestion: If person is conscious, wash out mouth with water. Get medical attention.
Skin Exposure: Wash skin with soap and water. If irritation develops or persists, get medical Data not available.
attention.
XIII. DISPOSAL CONSIDERATIONS:
Eye Exposure: Immediately flush eyes with water for at least 15 minutes. Get medical attention.
Dispose of in accordance with federal, state and local environmental regulations. Contact a
V. FIRE FIGHTING MEASURES: licensed professional waste disposal service to dispose of this material.
Flash Point: 21-55掳C (70-131掳F)
XIV. TRANSPORT INFORMATION:
Autoignition Temperature: Data not available.
Explosion: Data not available. D.O.T.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide. Proper Shipping Name: ISOPROPANOL (ISOPROPYL ALCOHOL), Solution
Firefighting: Wear protective clothing and self-contained breathing apparatus to prevent UN Number: UN1219
contact with skin and eyes. Hazard Class: 3 Flammable liquids
Packing Group: Packing Group II
VI. ACCIDENTAL RELEASE MEASURES: Hazard Label: 3
Wear appropriate personal protective equipment as indicated in Section VIII. Absorb liquid with IATA
an absorbent material. Transfer contaminated absorbent to a closed chemical waste container Proper Shipping Name: ISOPROPANOL (ISOPROPYL ALCOHOL), Solution
for disposal. Wash spill site after material has been picked up for disposal. UN Number: UN1219
ICAO/IATA Class: 3 Flammable liquids
VII. HANDLING AND STORAGE: Packing Group: II
Store at room temperature in tightly closed container. Store away from ignition sources. Hazard Label: 3
VIII. EXPOSURE CONTROLS/PERSONAL XV. REGULATORY INFORMATION:
Ventilation System: A system of local and general exhaust is recommended. US Regulations/Classifications:
Skin Protection: Wear compatible chemical resistant gloves and protective clothing. Harmful. Flammable.
Eye protection: Wear chemical safety goggles. Maintain emergency eyewash and shower in Harmful if swallowed. Irritating to eyes and skin.
work area. In case of contact with eyes, wash thoroughly and seek medical attention.
Components with limit values that require monitoring at the workplace: SARA 313 listed: 67-63-0 propan-2-ol
CAS# 67-63-0: propan-2-ol: IARC (international Agency for Research on Cancer): 67-63-0 propan-2-ol
漏 2008 Cell Signaling Technology, Inc.




PEL: 980 mg/m3, 400 ppm
XVI. OTHER INFORMATION:
REL: Short term value 1225 mg/m3, 500 ppm
This product is not intended for use in humans. To the best of our knowledge, this document is
Long term value: 980 mg/m3, 400 ppm
accurate. It is intended to serve as a guide for safe use of this product in a laboratory setting by
TLV: Short term value: 984 mg/m3, 400 ppm experienced personnel. The burden of safe use of this material rests entirely with the user. The
Long term value: 492 mg/m3, 200 ppm above information is believed to be accurate but is not necessarily all-inclusive and shall be
used only as a guide. Cell Signaling Technology, Inc., shall not be held liable for any damage
resulting from the handling of or from contact with the above product.


Orders n 877-616-CELL (2355) orders@cellsignal.com Support n 877-678-TECH (8324) info@cellsignal.com Web n www.cellsignal.com
Material Safety Data Sheet (MSDS) for
Protease Inhibitor Cocktail (200X)
New 03/08


I. IDENTIFICATION: IX. EXPOSURE CONTROLS/PERSONAL PROTECTION:
Appearance: Liquid
Product name: Protease Inhibitor Cocktail (200X)
Odor: Data not available
Product Catalog Number: Component of kit #9002 and #9003
pH: Data not available
CAS number: None
Boiling Point: Data not available
Manufacturer Supplier: Cell Signaling Technology庐
Melting Point: Data not available
3 Trask Lane
Freezing Point: Data not available
Danvers, MA 01923 USA
Volatile Organic Compounds (VOC): Data not available
1-978-867-2300 TEL
Autoignition temp. Data not available
1-978-867-2400 FAX
Solubility: Data not available
1-978-578-6737 Emergency Phone
II. COMPOSITION/INFORMATION ON INGREDIENTS: X. STABILITY AND REACTIVITY:
Ingredient CAS# Percent Stability: Stable.
Dimethyl sulfoxide (DMSO) 67-68-5 >96% Conditions to avoid: Exposure to moisture may affect product quality.
Hazardous Decomposition: Acid chlorides, phosphorus halides, strong acids, strong oxidiz-
4-(2-aminoethyl)benenesulfonyl fluoride hydrochloride 30827-99-7 2.49%
ing agents, strong reducing agents.
Aprotinin 9087-70-1 0.05%
Hazardous polymerization: Will not occur.
Bestatin hydrochloride 65391-42-6 0.12%
N-(trans-epoxysuccinyl)-L-leucine 4-guanidinobutylamide 66701-25-5 0.09% XI. TOXICOLOGICAL INFORMATION:
Leupeptin hemisulfate 103476-89-7 0.1%
Skin Exposure: May cause skin irritation. May be harmful if absorbed through skin.
Pepstatin A 26305-03-3 0.1%
Eye Exposure: May cause eye irritation.
Inhalation: May be harmful if inhaled. Material may be irritating to mucous membrane and
III. HAZARD IDENTIFICATION: upper respiratory tract.
Ingestion: May be harmful if swallowed.
Combustible.
Target organs: Eyes. Skin. Readily absorbed through skin. Target organs: Eyes, skin.
HMIS Rating: Health: 0 Flammability: 2 Reactivity: 0 To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
NFPA Rating: Health: 0 Flammability: 2 Reactivity: 0
XII. ECOLOGICAL INFORMATION:
IV. FIRST AID MEASURES: Data not available.
Inhalation: Remove to fresh air. If breathing is difficult, get medical attention.
XIII. DISPOSAL CONSIDERATIONS:
Ingestion: If person is conscious, wash out mouth with water. Get medical attention.
Skin Exposure: Wash skin with soap and water. If irritation develops or persists, get medical Dispose of in accordance with federal, state and local environmental regulations. Contact a
attention. licensed professional waste disposal service to dispose of this material.
Eye Exposure: Immediately flush eyes with water for at least 15 minutes. Get medical attention.
XIV. TRANSPORT INFORMATION:
V. FIRE FIGHTING MEASURES:
D.O.T.
Flash Point: 188.6掳F, 87掳C Method: closed cup. Proper Shipping Name: Combustible liquid, n.o.s
Autoignition Temperature: Not applicable. UN# NA1993.
Explosion: Not applicable. Class: Combustible Liquid.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide. Packing Group: Packing Group III.
Firefighting: Wear protective clothing and self-contained breathing apparatus to prevent Hazard Label: None.
contact with skin and eyes. PIH: Not PIH.
Note: Combustible liquid. Emits toxic fumes under fire conditions. IATA
Proper Shipping Name: None.
VI. ACCIDENTAL RELEASE MEASURES: This substance is considered non-hazardous for air transport.
Wear appropriate personal protective equipment as indicated in Section VIII. Absorb liquid with
XV. REGULATORY INFORMATION:
an absorbent material. Transfer contaminated absorbent to a closed chemical waste container
for disposal. Wash spill site after material has been picked up for disposal. US Regulations/Classifications: Combustible.
Target organs: Eyes. Skin. Readily absorbed through skin.
VII. HANDLING AND STORAGE:
SARA Listed: No.
Store at -20掳C in tightly closed container under inert gas. Hygroscopic. Avoid prolonged or
Canada (WHMIS): DSL: No, NDSL: No.
repeated exposure. Avoid contact with eyes, respiratory system, skin, and clothing. Wash
thoroughly after handling. DMSO is readily absorbed through the skin and may carry materials
XVI. OTHER INFORMATION:
with known or unknown toxicological properties into the body.
This product is not intended for use in humans. To the best of our knowledge, this document is
VIII. EXPOSURE CONTROLS/PERSONAL
漏 2008 Cell Signaling Technology, Inc.




accurate. It is intended to serve as a guide for safe use of this product in a laboratory setting by
experienced personnel. The burden of safe use of this material rests entirely with the user. The
Ventilation System: A system of local and general exhaust is recommended.
above information is believed to be accurate but is not necessarily all-inclusive and shall be
Skin Protection: Wear compatible chemical resistant gloves and protective clothing.
used only as a guide. Cell Signaling Technology, Inc., shall not be held liable for any damage
Eye protection: Wear chemical safety goggles. Maintain emergency eyewash and shower in
resulting from the handling of or from contact with the above product.
work area.




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Material Safety Data Sheet (MSDS) for
RNase A Solution New 03/08


I. IDENTIFICATION: IX. EXPOSURE CONTROLS/PERSONAL PROTECTION:
Product name: RNase A solution Physical State: Liquid
Product Catalog Number: Component of kit #9002 and #9003 Appearance: Colorless
CAS number: None Odor: Odorless
Manufacturer Supplier: Cell Signaling Technology庐 pH : 7.5
Boiling Point:
3 Trask Lane Data not available
Melting Point:
Danvers, MA 01923 USA Data not available
Volatile Organic Compounds (VOC):
1-978-867-2300 TEL Data not available
Solubility in water:
1-978-867-2400 FAX Readily miscible in water
1-978-578-6737 Emergency Phone
X. STABILITY AND REACTIVITY:
II. COMPOSITION/INFORMATION ON INGREDIENTS:
Stability: Stable.
According to 29 CFR 1910.1200(d), hazardous ingredients at less than <1% and carcinogens
Conditions to avoid: Strong oxidizing agents.
at less than <0.1% therefore considered non-hazardous. Any hazardous or carcinogenic
Hazardous Decomposition: May form carbon dioxide and carbon monoxide.
ingredients meeting these criteria are listed below.
XI. TOXICOLOGICAL INFORMATION:
Ingredient CAS# Percent
May cause skin irritation.
Glycerol 56-81-5 50%
May be toxic if absorbed through skin or ingested.
May cause eye irritation.
III. HAZARD IDENTIFICATION:
Target organs: Kidneys.
Emergency Overview of Hazardous ingredient: Glycerol (CAS# 56-81-5)
Prolonged exposure may cause nausea, headache, and vomiting.
Caution: Avoid contact and inhalation.
XII. ECOLOGICAL INFORMATION:
Irritant. Irritating to eyes, respiratory system, skin.
NFPA Rating: Health: 1 Flammability: 0 Reactivity: 0 Data not available.

XIII. DISPOSAL CONSIDERATIONS:
Target organ: Kidneys.
Dispose of in accordance with federal, state and local environmental regulations.
IV. FIRST AID MEASURES:
XIV. TRANSPORT INFORMATION:
Inhalation: Remove to fresh air. If breathing is difficult, get medical attention.
Ingestion: If swallowed, rinse mouth with water provided person is conscious. Get medical D.O.T.
attention. Proper Shipping Name: None.
Skin Exposure: In case of contact, wash skin with soap and water. This substance is considered non-hazardous for transport.
Eye Exposure: In case of contact with eyes, immediately flush eyes with water for at least 15 IATA
minutes. Get medical attention. Proper Shipping Name: None.
This substance is considered non-hazardous for air transport.
V. FIRE FIGHTING MEASURES:
XV. REGULATORY INFORMATION:
Flash Point: Data not available.
Autoignition Temperature: Data not available. EU Regulations/Classifications: Data not available.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
US Regulations/Classifications: Irritant. Irritating to eyes, respiratory system, skin.
Firefighting: Wear protective clothing and self-contained breathing apparatus to prevent
contact with skin and eyes. Caution: Avoid contact and inhalation.
Target organ(s): Kidneys.
VI. ACCIDENTAL RELEASE MEASURES:
In case of contact with eyes, wash thoroughly and seek medical attention
Wear appropriate personal protective equipment as indicated in Section VIII. Absorb liquid with
an absorbent material. Transfer contaminated absorbent to a closed chemical waste container SARA Listed: No.
for disposal. Wash spill site after material has been picked up for disposal. Canada (WHMIS): DSL: No, NDSL: No.
VII. HANDLING AND STORAGE: XVI. OTHER INFORMATION:
Store at 鈥?20掳C in tightly closed container. Avoid inhalation and contact with eyes and skin.
This product is not intended for use in humans. To the best of our knowledge, this document is
Avoid prolonged or repeated exposure.
accurate. It is intended to serve as a guide for safe use of this product in a laboratory setting by
VIII. EXPOSURE CONTROLS/PERSONAL experienced personnel. The burden of safe use of this material rests entirely with the user. The
above information is believed to be accurate but is not necessarily all-inclusive and shall be
Ventilation System: A system of local and general exhaust is recommended.
used only as a guide. Cell Signaling Technology, Inc., shall not be held liable for any damage
Skin Protection: Wear compatible chemical resistant gloves and protective clothing.
resulting from the handling of or from contact with the above product.
Eye protection: Wear chemical safety goggles. Maintain emergency eyewash and shower in
work area.
漏 2008 Cell Signaling Technology, Inc.




Orders n 877-616-CELL (2355) orders@cellsignal.com Support n 877-678-TECH (8324) info@cellsignal.com Web n www.cellsignal.com
Material Safety Data Sheet (MSDS) for
Micrococcal Nuclease New 03/08


I. IDENTIFICATION: IX. EXPOSURE CONTROLS/PERSONAL PROTECTION:
Physical State: Liquid
Product name: Micrococcal Nuclease
Appearance: Colorless
Product Catalog Number: Component of kit #9002 and #9003
Odor: Odorless
CAS number: None
pH: 7.4 at 25掳C
Manufacturer Supplier: Cell Signaling Technology庐
Boiling Point: Data not available
3 Trask Lane
Melting Point: Data not available
Danvers, MA 01923 USA
Volatile Organic Compounds (VOC): Data not available
1-978-867-2300 TEL
Solubility: Readily miscible in water
1-978-867-2400 FAX
1-978-578-6737 Emergency Phone
X. STABILITY AND REACTIVITY:
II. COMPOSITION/INFORMATION ON INGREDIENTS:
Stability: Stable.
According to 29 CFR 1910.1200(d), hazardous ingredients at less than <1% and carcinogens Conditions to avoid: Strong oxidizing reagents.
at less than <0.1% therefore considered non-hazardous. Any hazardous or carcinogenic Hazardous Decomposition: May form carbon dioxide and carbon monoxide.
ingredients meeting these criteria are listed below.
XI. TOXICOLOGICAL INFORMATION:
This product may contain the following hazardous ingredients:
May cause skin irritation.
Ingredient CAS# Percent May be toxic if absorbed through skin or ingested.
Glycerol 56-81-5 50% May cause eye irritation.
Target organs: Kidneys.
III. HAZARD IDENTIFICATION: Prolonged exposure may cause nausea, headache, and vomiting.
Emergency Overview of Hazardous ingredient: Glycerol (CAS# 56-81-5)
XII. ECOLOGICAL INFORMATION:
Irritant. Irritating to eyes, respiratory system, skin.
Data not available.
Caution: Avoid contact and inhalation.
Target organ: Kidneys.
XIII. DISPOSAL CONSIDERATIONS:
NFPA Rating: Health: 3 Flammability: 3 Reactivity: 0
Dispose of in accordance with federal, state and local environmental regulations.

XIV. TRANSPORT INFORMATION:
IV. FIRST AID MEASURES:
D.O.T.
Inhalation: Remove to fresh air. If breathing is difficult, get medical attention.
Proper Shipping Name: None.
Ingestion: If person is conscious, wash out mouth with water. Get medical attention.
This substance is considered non-hazardous for transport.
Skin Exposure: In case of contact, wash skin with soap and water.
Eye Exposure: In case of contact with eyes, immediately flush eyes with water for at least 15 IATA
minutes. Get medical attention. Proper Shipping Name: None.
This substance is considered non-hazardous for transport.
V. FIRE FIGHTING MEASURES:
XV. REGULATORY INFORMATION:
Flash Point: Data not available.
Autoignition Temperature: Data not available. EU Regulations/Classifications: Data not available.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
US Regulations/Classifications:
Firefighting: Wear protective clothing and self-contained breathing apparatus to prevent
Irritant. Irritating to eyes, respiratory system, skin.
contact with skin and eyes.
Caution: Avoid contact and inhalation.
VI. ACCIDENTAL RELEASE MEASURES: Target organ(s): Kidneys.
In case of contact with eyes, wash thoroughly and seek medical attention.
Wear appropriate personal protective equipment as indicated in Section VIII. Absorb liquid with
SARA Listed: No.
an absorbent material. Transfer contaminated absorbent to a closed chemical waste container
for disposal. Wash spill site after material has been picked up for disposal. Canada (WHMIS): DSL No, NDSL No.
VII. HANDLING AND STORAGE: XVI. OTHER INFORMATION:
Store at鈥?20掳C in tightly closed container. Avoid inhalation and contact with eyes and skin.
This product is not intended for use in humans. To the best of our knowledge, this document is
Avoid prolonged or repeated exposure.
accurate. It is intended to serve as a guide for safe use of this product in a laboratory setting by
VIII. EXPOSURE CONTROLS/PERSONAL experienced personnel. The burden of safe use of this material rests entirely with the user. The
above information is believed to be accurate but is not necessarily all-inclusive and shall be
Ventilation System: A system of local and general exhaust is recommended.
used only as a guide. Cell Signaling Technology, Inc., shall not be held liable for any damage
Skin Protection: Wear compatible chemical resistant gloves and protective clothing.
resulting from the handling of or from contact with the above product.
Eye protection: Wear chemical safety goggles. Maintain emergency eyewash and shower in
work area.
漏 2008 Cell Signaling Technology, Inc.




Orders n 877-616-CELL (2355) orders@cellsignal.com Support n 877-678-TECH (8324) info@cellsignal.com Web n www.cellsignal.com
Material Safety Data Sheet (MSDS) for
Proteinase K Solution New 03/08


I. IDENTIFICATION: IX. EXPOSURE CONTROLS/PERSONAL PROTECTION:
Product name: Proteinase K Solution Physical State: Liquid
Product Catalog Number: Component of kit #9002 and #9003 Appearance: Colorless
CAS number: None Odor: Odorless
Manufacturer Supplier: Cell Signaling Technology庐 pH: 7.5 at 25掳C
Boiling Point:
3 Trask Lane Data not available
Melting Point:
Danvers, MA 01923 USA Data not available
Volatile Organic Compounds (VOC):
1-978-867-2300 TEL Data not available
Solubility in water:
1-978-867-2400 FAX Readily miscible in water
1-978-578-6737 Emergency Phone
X. STABILITY AND REACTIVITY:
II. COMPOSITION/INFORMATION ON INGREDIENTS:
Stability: Stable.
According to 29 CFR 1910.1200(d), hazardous ingredients at less than <1% and carcinogens
Conditions to avoid: Strong oxidizing agents.
at less than <0.1% therefore considered non-hazardous. Any hazardous or carcinogenic
Hazardous Decomposition: May form carbon dioxide and carbon monoxide.
ingredients meeting these criteria are listed below.
XI. TOXICOLOGICAL INFORMATION:
Ingredient CAS# Percent
May cause skin irritation.
Glycerol 56-81-5 50%
May be toxic if absorbed through skin or ingested.
May cause eye irritation.
III. HAZARD IDENTIFICATION:
Target organs: Kidneys
Emergency Overview of Hazardous ingredient: Glycerol (CAS# 56-81-5)
Prolonged exposure may cause nausea, headache, and vomiting.
Irritant. Irritating to eyes, respiratory system, skin.
XII. ECOLOGICAL INFORMATION:
Caution: Avoid contact and inhalation.
Data not available.
NFPA Rating: Health: 1 Flammability: 0 Reactivity: 0
XIII. DISPOSAL CONSIDERATIONS:
Target organ: Kidneys. Dispose of in accordance with federal, state and local environmental regulations.
IV. FIRST AID MEASURES: XIV. TRANSPORT INFORMATION:
Inhalation: Remove to fresh air. If breathing is difficult, get medical attention. D.O.T.
Ingestion: If person is conscious, wash out mouth with water. Get medical attention. Proper Shipping Name: None.
Skin Exposure: Wash skin with soap and water. If irritation develops or persists, get medical This substance is considered non-hazardous for transport.
attention. IATA
Eye Exposure: Immediately flush eyes with water for at least 15 minutes. Get medical attention. Proper Shipping Name: None.
This substance is considered non-hazardous for air transport.
V. FIRE FIGHTING MEASURES:
XV. REGULATORY INFORMATION:
Flash Point: Data not available.
Autoignition Temperature: Data not available. EU Regulations/Classifications: Data not available.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
US Regulations/Classifications: Irritant. Irritating to eyes, respiratory system, skin.
Firefighting: Wear protective clothing and self-contained breathing apparatus to prevent
contact with skin and eyes. Caution: Avoid contact and inhalation.
Target organ(s): Kidneys.
VI. ACCIDENTAL RELEASE MEASURES:
In case of contact with eyes, wash thoroughly and seek medical attention
Wear appropriate personal protective equipment as indicated in Section VIII. Absorb liquid with
an absorbent material. Transfer contaminated absorbent to a closed chemical waste container SARA Listed: No.
for disposal. Wash spill site after material has been picked up for disposal. Canada (WHMIS): DSL: No, NDSL: No.
VII. HANDLING AND STORAGE: XVI. OTHER INFORMATION:
Avoid inhalation and contact with eyes and skin. Avoid prolonged or repeated exposure.
This product is not intended for use in humans. To the best of our knowledge, this document is
Store at鈥?20掳C in tightly closed container.
accurate. It is intended to serve as a guide for safe use of this product in a laboratory setting by
VIII. EXPOSURE CONTROLS/PERSONAL experienced personnel. The burden of safe use of this material rests entirely with the user. The
above information is believed to be accurate but is not necessarily all-inclusive and shall be
Ventilation System: A system of local and general exhaust is recommended.
used only as a guide. Cell Signaling Technology, Inc., shall not be held liable for any damage
Skin Protection: Wear compatible chemical resistant gloves and protective clothing.
resulting from the handling of or from contact with the above product.
Eye protection: Wear chemical safety goggles. Maintain emergency eyewash and shower in
work area.
漏 2008 Cell Signaling Technology, Inc.




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