#9901 MSDS Material Safety Data Sheet (MSDS) for
LY294002 (PI3 Kinase Inhibitor) 166B Cummings Center I Beverly, MA 01915
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Emergency and First Aid Procedures
I. Identification Swallowing鈥擶ash out mouth with water, provided person is conscious.
Call a physician.
Product name: LY294002 (PI3 Kinase Inhibitor)
Skin鈥擨n case of contact, immediately wash skin with soap and copious
Chemical name: 2-(4-morpholino)-8-phenyl-4H-1-benzopyran-4-one
amounts of water.
CAS number: 154447-36-6
Inhalation鈥擨f inhaled, remove to fresh air. If breathing becomes difficult,
Empirical formula: C19 H17 NO3 call a physician.
Molecular weight: 307.35 Eyes鈥擨n case of contact with eyes, flush with copious amounts of water
for at least 15 minutes. Assure adequate flushing by separating eyelids with
Chemical family: Benzopyranone
fingers. Consult a physician.
II. Physical Data VI. Reactivity Data
Boiling point: N/A (solid compound)
Stability/Conditions to avoid: Not reactive as far as is known.
Specific gravity: N/A (solid compound)
Incompatibility/Materials to avoid: Strong oxidizing agents.
Vapor density: N/A (solid compound)
Combustion/Decomposition products: Carbon monoxide, carbon
dioxide, nitrogen oxides.
Percent volatile by volume: N/A (solid compound)
Hazardous polymerization: Not susceptible to polymerization.
Freezing point: Solid at working temperatures.
Vapor pressure at 20掳C: N/A (solid compound)
VII. Spill or Leak Procedures
Solubility in water: <10 mg/ml
Steps to be taken if material is spilled or released: Wear self-
Appearance: Off-white to cream-colored solid.
contained breathing apparatus, rubber boots and rubber gloves. Sweep up,
place in bag and dispose of properly. Wash spill site after sweeping up.
III. Ingredients Waste disposal method: Dissolve the material in a combustible solvent
and burn in an EPA-licensed chemical incinerator equipped with an after-
Material: Supplied as pure compound.
burner and scrubber.
IV. Fire and Explosion Hazard Data
VIII. Special Protection Information
Flash point: N/A (solid compound)
Respiratory protection: Avoid inhalation. Use NIOSH/MSHA-approved
Extinguishing media: Fire extinguishing media should match other respirator.
materials in fire.
Ventilation: Use mechanical exhaust.
Special fire fighting procedures: If involved in fire, don NIOSH/MSHA-
Protective equipment: Wear suitable protective clothing, chemical
approved self-contained breathing apparatus, flame/chemical resistant.
resistant gloves and lab safety glasses.
Unusual fire and explosion hazards: Emits toxic fumes under fire
conditions.
IX. Special Precautions
Precautions to be taken in handling and storage: This compound is
V. Health Hazard Data
sold only for research use by personnel familiar with the toxicology of
Threshold Limit Value (TLV) and source: Data not available. organic chemicals and who are well trained in good laboratory habits, such
as avoiding spills, keeping hands clean at all times and not rubbing eyes
Acute effects of overexposure: May cause skin irritation. To the best of
with hands while working in the laboratory.
our knowledge, the chemical, physical and toxicological properties have
not been thoroughly investigated. This compound is sold only in milligram quantities for use in dilute solu-
tions in biological research. No other use is intended, and any other use
漏 2001 Cell Signaling Technology, Inc.
Swallowing: May be harmful if swallowed.
may involve substantial hazards.
Skin absorption: May be harmful if absorbed through the skin.
This compound is to be stored as tightly stoppered solutions kept under
nitrogen or argon, or kept as supplied in a sealed glass ampule.
Inhalation: May be harmful if inhaled. Material may be irritating to
mucous membranes and upper respiratory tract.
The above information is believed to be correct but does not purport to be
all inclusive and shall be used only as a guide for experienced personnel.
Skin contact: May be harmful.
Cell Signaling Technology, Inc., shall not be held liable for any damage
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Eye contact: May cause eye irritation. resulting from the handling of or from contact with the above product. The
burden of safe use of this material rests entirely with the user.
Chronic effects of overexposure: May be harmful.
Revised: August 2001
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