#9902 MSDS Material Safety Data Sheet (MSDS) for
Serine/Threonine Phosphatase Inhibitor
(Calyculin A)
I. Identification Emergency and First Aid Procedures
After Inhalation: If inhaled, remove to fresh air; if breathing is difficult, give oxygen; if
Product name: Serine/Threonine Phosphatase Inhibitor (Calyculin A)| breathing stops, give artificial respiration.
Chemical name: Calyculin A After swallowing: If swallowed, wash out mouth with copious amounts of water; call
CAS number: 0932-7-2 physician.
Empirical formula: C50 H8 N4 O5 P After Skin Contact: Flush with copious amounts of water; remove contaminated clothing
Molecular weight: 009.8 and shoes; call a physician.
Chemical family: Polyene phosphate After Eye Contact: Flush with copious amounts of water; assure adequate flushing by
Manufacturer Supplier: Cell Signaling Technology separating the eyelids with fingers; call a physician.
3 Trask Lane
VI. Reactivity Data
Danvers, MA 0923 USA
978-867-2300 TEL
Stability/conditions to avoid: Protect from light and heat.
978-867-2400 FAX
Incompatibility/Materials to avoid: Avoid acids an bases.
978-578-6737 EMERGENCY TEL
Combustion/Decomposition products: Undetermined
II. Physical Data
VII. Spill or Leak Procedures
Boiling point: N/A (solid compound)
Accidental Release Meassures:
Specific gravity: N/A (solid compound)
Vapor density: N/A (solid compound) Saftey Precautions: Cordon off spill area, wear self contained breathing apparatus,
Percent volatile by volume: N/A (solid compound) protective clothing, and heavy rubber gloves.
Freezing point: Solid at working temperatures Cleaning: Absorb solutions with finely-powdered liquid binding material (universal binders);
Vapor pressure at 20掳C: N/A (solid compound) decontaminate surfaces and equipment by scrubbing with alcohol.
Solubility in water: Not soluble Waste disposal method: Dispose of as cancer suspect agent. Observe all federal, state,
Organic Solvents: Soluble in DMSO or ethanol. and local regulations when storing or disposing of this substance. For assistance, contact
Appearance: Clear or whitish film adhering to inside of tube the district director of the Environmental Protection Agency.
III. Ingredients Precautions
Material: Supplied as pure compound Safety shower and eye bath.
Do not get in eyes, on skin, or on clothing.
IV. Fire and Explosion Hazard Data
Wash thoroughly after handling.
Flash point: N/A (solid compound) Observe all federal, state and local laws.
Auto-ignition temperature: N/A
VIII. Special Protection Information
Danger of explosion: None
Extinguishing media: Compound not to be used above milligram amounts; fire extin- Respiratory protection: Do not work with this compound in powder or aerosol form.
guishing media should match other materials in fire. Ventilation: Do not work with this compound in powder or aerosol form.
Special fire fighting procedures: If involved in fire, don NIOSH/MSHA-approved self- Protective equipment: Wear suitable protective clothing, chemical resistant gloves and
contained breathing apparatus that is flame/chemical resistant. lab safety glasses.
Unusual fire and explosion hazards: May emit toxic fumes under fire conditions, (i.e.
IX. Special Precautions
carbon monoxide and carbon dioxide).
Precautions to be taken in handling and storage: This compound is sold only for
V. Health Hazard Data: Special Hazard
research use by scientists familiar with the toxicology of organic chemicals and tumor
TUMOR PROMOTER. Gloves and mask should be worn when using this compound. Care promoters and who are well trained in good laboratory habits, such as keeping hands clean
must be taken to prevent contact thruogh all routes of exposure. at all times and not rubbing eyes with hands while working in the laboratory.
Hazard Description: may be an irritant; may cause irritation to eyes, skin, mucous mem- This compound is sold only in milligram quantities for use in extremely dilute solutions
branes. Information pertaining to particular dangers for man and enviornment: in biological research. No other use is intended and any other use involves substantial
hazards.
HMIS Ratings: Health = Flammability = 0 Reactivity = 0
The above information is believed to be correct but does not purport to be all inclusive and
Chemical listed as carcinogen or potential carcinogen: No
shall be used only as a guide for experienced personnel. Cell Signaling Technology, Inc.,
Signs and Symptoms of Exposure shall not be held liable for any damage resulting from the handling of or from contact with
Acute effects of overexposure鈥擭one known the above product. The burden of safe use of this material rests entirely with the user.
Acute Overexposure Revised: April 2004
Acute effects of swallowing Not known
Acute effects of skin absorption Not known
漏 2007 Cell Signaling Technology, Inc.
Acute effects of inhalation Not known; presumed to be very toxic
Acute effects of skin contact Not known
Acute effects of eye contact Not known; presumed to be very toxic
Chronic effects of overexposure: Effects in humans not known; may be a carcinogen
or tumor promoter
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