EMS CATALOG NO: 11480
EMS PRODUCT: ACETATE BUFFER
DATE: 19 January 2002
PAGE NUMBER: One of 5
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered accurate. However, no
warranty is expressed or implied regarding the accuracy of these data or the results to be
obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for personal injury or property
damage to vendees, users or third parties caused by the material. Such vendees or users
assume all risks associated with the use of the material.
Section 1: Chemical Product and Company Identification
ELECTRON MICROSCOPY SCIENCES
321 MORRIS ROAD email: sgkcck@aol.com
P.O. BOX 251 WEB: www.emsdiasum.com
FORT WASHINGTON, PA 19034
215-646-1566 / fax 215-646-8931
24 HOUR EMERGENCY PHONE NUMBER CHEMTREC: (800) 424-9300
FOR PRODUCT AND SALES INFORMATION
CONTACT ELECTRON MICROSCOPY SCIENCES OFFICE ABOVE.
Section 2. Composition/Information on Ingredients
Component CAS Registry# Percent Concentration ACGIH TLV OSHA PEL
Sodium Acetate Trihydrate 6131-90-4 24 -- 42 Not Available Not Available
10 ppm 10 ppm
Acetic Acid 64-19-7 45 - 50 3 3
25 mg/m 25 mg/m
Water, Deionized
7732-18-5 Balance Not Available Not Available
Section 3 : Hazard Identification
Emergency Overview: Danger! Corrosive liquid. May be fatal if swallowed. Causes severe burns to
all areas of contact. Harmful if inhaled. Inhalation may cause lung and tooth damage. Immediately
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wash areas of contact with plenty of water for at least 15 minutes. If ingested, give large quantity
of water. Do not induce vomiting.
Target Organs: eyes, skin, respiratory system, teeth.
Eye Contact: Eye contact may cause severe eye damage followed by loss of sight. Vapor
exposure may cause watering and irritation to eyes.
Inhalation: Inhalation of concentrated vapors may cause serious damage to the lining of the nose,
throat and lungs.
Skin Contact: May cause serious damage to the skin. Effects may include redness, pain, skin
burns.
Ingestion: Swallowing can cause severe injury leading to death. Symptoms include sore throat,
vomiting and death.
Chronic Effects/Carcinogenicity: Repeated exposures may cause erosion of exposed front teeth,
darkening of skin and chronic inflammation of the nose, throat and bronchial tubes.
IARC - No.
NTP - No.
OSHA - No.
Teratology (Birth Defect) Information: Mutation data cited in 'Registry of Toxic Effects of Chemical
Substances' for Acetic Acid.
Reproductive Information: No information found.
Section 4. First Aid Measures
Eye Contact: Irrigate immediately with large quantity of water for at least 15 minutes. Get medical
attention immediately.
Inhalation: Remove to fresh air. Give artificial respiration if necessary. If breathing is difficult, give
oxygen.
Skin Contact: Flush with plenty of water for at least 15 minutes. Call a physician if irritation
develops.
Ingestion: Do not induce vomiting. Give large quantity of water. Call a physician immediately.
Section 5. Fire Fighting Measures
Flash Point: 109掳F (Acetic Acid) Method Used: CC
LFL: 5.4% (Acetic Acid) UFL: 16.0% (Acetic Acid)
Extinguishing Media: Use water spray, dry chemical, alcohol foam, or carbon dioxide for
extinguishing the surrounding fire. Water spray can be used to dilute spills to non-flammable
mixtures.
Fire & Explosion Hazards: Above flash point, vapor-air mixtures are explosive within flammable
limits noted above. Contact with strong oxidizers may cause fire. Vapors can flow along surfaces
to distant ignition source and flash back. Reacts with most metals to produce hydrogen gas,
which can form explosive mixture with air.
Fire Fighting Instructions: Use normal procedures/instructions.
Fire Fighting Equipment: Use protective clothing and breathing equipment appropriate for the
surrounding fire.
Section 6. Accidental Release Measures
Absorb with suitable material (paper towels, etc.) and dispose of in accordance with local
regulations. Ventilate, if necessary, site of spillage well to evaporate remaining liquid and dispel
vapor.
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Section 7. Handling and Storage
As with all chemicals, wash hands thoroughly after handling. Avoid contact with eyes and skin.
Protect from freezing and physical damage.
SAFETY STORAGE CODE: Corrosive
Section 8. Exposure Control/Personal Protection
Engineering Controls: A system of local and/or general exhaust is recommended to keep
employee exposures below the Airborne Exposure Limit.
Respiratory Protection: Work with adequate ventilation or wear respirator with acid gas/organic
vapor cartridge.
Skin Protection: Chemical resistant gloves.
Eye Protection: Safety glasses or goggles.
Section 9. Physical and Chemical Properties
Appearance: Clear, colorless liquid pH: 4 - 5
Odor: strong vinegar Boiling Point(掳C): approximately 100 - 118
Solubility in Water: Infinite Melting Point(掳C): approximately 0 - 16.6
Specific Gravity: approximately 1.1 - 1.2 Vapor Pressure: Not Applicable.
Section 10. Stability and Reactivity
Chemical Stability: Stable under normal conditions of use and storage. Acetic acid contracts
slightly upon freezing which may cause the container to burst.
Incompatibility: Strong bases, strong oxidizers, chromic acid, sodium peroxide, nitric acid,
perchloric acid.
Hazardous Decomposition Products: When heated to decomposition it emits irritating fumes.
Hazardous Polymerization: Will not occur.
Section 11. Toxicological Information
LD50, Oral, Rat (Acetic Acid): 3310 mg/kg, details of toxic effects not reported other than lethal
dose value; LD50, Dermal, Rabbit (Acetic Acid): 1.06 g/kg; LC50, Inhalation, Mouse (Acetic Acid):
5620 ppm/1 hr.; LD50, Oral, Rat (Sodium Acetate): 3530 mg/kg; Information obtained from
RTECS ("Registry of Toxic Effects of Chemical Substances").
Section 12. Ecological Information
Ecotoxicological Information: Acetic Acid has high biochemical oxygen demand, and a potential to
cause oxygen depletion in ueous systems, low potential to affect aquatic organisms and a low
potential to affect the growth of some plant seedlings.
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Chemical Fate Information: Acetic Acid has low potential to bioconcentrate. If released to water or
soil, Acetic Acid will biodegrade readily.
Section 13. Disposal Considerations
Neutralize with 5% Sodium Hydroxide or Sodium Carbonate solutions, then pour into the drain
while flushing with water, if allowed. If not allowed, save for recovery or recycling in an approved
waste disposal facility. Always dispose of in accordance with local, state and federal regulations.
Section 14. Transport Information
D.O.T. Shipping
Acetic Acid Solution
Name:
D.O.T. Hazard
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Class:
U.N. / N.A.
UN2790
Number:
Packing Group: III
D.O.T. Label : Corrosive(8)
Section 15. Regulatory Information (Not meant to be all inclusive - selected
regulation represented)
OSHA Status: These items meet the OSHA Hazard Communication Standard (29 CFR
1910.1200) definition of a hazardous material.
TSCA Status: All components of this solution are listed on the TSCA Inventory or are mixtures
(hydrates) of items listed on the TSCA Inventory.
CERCLA Reportable Quantity: Acetic Acid - 5,000 pounds.
Sara Title III:
Section 302 Extremely Hazardous Substances:
Section 311/312 Hazardous Catagories: Acute, Chronic, Fire, Reactivity: Yes Pressure: No
Section 313 Toxic Chemicals: No.
RCRA Status: No.
California: None reported.
Florida: Acetic Acid is listed on Florida's Toxic Substances List.
Pennsylvania: Acetic Acid is listed as an Environmental Hazard on the state's Hazardous
Substances List.
WHMIS Information (Canada):
E: Corrosive Material.
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Section 16. Other Information
NFPA Health: Flammability: Reactivity:
Special Notice Key: None
Ratings: 2 0 0
HMIS Health: Flammability: Reactivity: Protective Equipment: B (Protective
Ratings: 2 0 0 Eyewear, Gloves)
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