PRODUCT #: 23320 NAME: 3-CHLOROANILINE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Tuesday, March 11, 1903 9:41AM
Sigma Chemical Co. Aldrich Chemical Co., Inc. Fluka Chemical Corp.
P.O. Box 14508 1001 West St. Paul 1001 West St. Paul
St. Louis, MO 63178 Milwaukee, WI 53233 Milwaukee, WI 53233
Phone: 314-771-5765 Phone: 414-273-3850 Phone: 414-273-3850
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CATALOG #: 23320
NAME: 3-CHLOROANILINE
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 108-42-9
MF: C6H6CLN
EC NO: 203-581-0
SYNONYMS
M-AMINOCHLOROBENZENE * 1-AMINO-3-CHLOROBENZENE * BENZENAMINE, 3-
CHLORO- (9CI) * 3-CHLOORANILINEN (DUTCH) * M-CHLORANILINE * M-
CHLOROANILINE * 3-CHLOROANILINE * 3-CHLOROBENZENAMINE * M-
CHLOROPHENYLAMINE * 3-CHLOROPHENYLAMINE * 3-CLOROANILINE (ITALIAN) *
FAST ORANGE GC BASE * ORANGE GC BASE *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
HIGHLY TOXIC (USA)
TOXIC (EU)
TOXIC BY INHALATION AND IN CONTACT WITH SKIN.
HARMFUL IF SWALLOWED.
IRRITATING TO EYES.
MAY CAUSE SENSITIZATION BY SKIN CONTACT.
READILY ABSORBED THROUGH SKIN.
TARGET ORGAN(S):
LIVER
KIDNEYS
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
DO NOT BREATHE VAPOR.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN.
WASH CONTAMINATED CLOTHING BEFORE REUSE.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
WATER SPRAY.
CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
Page 1
PRODUCT #: 23320 NAME: 3-CHLOROANILINE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Tuesday, March 11, 1903 9:41AM
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
EVACUATE AREA.
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
ABSORB ON SAND OR VERMICULITE AND PLACE IN CLOSED CONTAINERS FOR
DISPOSAL.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT
GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.
SAFETY SHOWER AND EYE BATH.
USE ONLY IN A CHEMICAL FUME HOOD.
DO NOT BREATHE VAPOR.
DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
READILY ABSORBED THROUGH SKIN.
WASH THOROUGHLY AFTER HANDLING.
HIGHLY TOXIC.
EYE IRRITANT.
SENSITIZER.
KEEP TIGHTLY CLOSED.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
COLORLESS TO LIGHT-BROWN LIQUID
PHYSICAL PROPERTIES
BOILING POINT: 95 TO 96C/11MM
MELTING POINT: 10 TO 8C
FLASHPOINT 244.40F
118C
VAPOR PRESSURE: 1MM 63.5 C
SPECIFIC GRAVITY: 1.215
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
STABILITY
STABLE.
CONDITIONS TO AVOID
HEAT
INCOMPATIBILITIES
ACIDS
ACID CHLORIDES
ACID ANHYDRIDES
CHLOROFORMATES
STRONG OXIDIZING AGENTS
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
TOXIC FUMES OF:
CARBON MONOXIDE, CARBON DIOXIDE
NITROGEN OXIDES
HYDROGEN CHLORIDE GAS
HAZARDOUS POLYMERIZATION
WILL NOT OCCUR.
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
MAY BE FATAL IF INHALED OR ABSORBED THROUGH SKIN.
HARMFUL IF SWALLOWED.
Page 2
PRODUCT #: 23320 NAME: 3-CHLOROANILINE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Tuesday, March 11, 1903 9:41AM
CAUSES EYE IRRITATION.
MAY CAUSE SKIN IRRITATION.
MATERIAL MAY BE IRRITATING TO MUCOUS MEMBRANES AND UPPER
RESPIRATORY TRACT.
MAY CAUSE ALLERGIC SKIN REACTION.
ABSORPTION INTO THE BODY LEADS TO THE FORMATION OF METHEMOGLOBIN
WHICH IN SUFFICIENT CONCENTRATION CAUSES CYANOSIS. ONSET MAY BE
DELAYED 2 TO 4 HOURS OR LONGER.
EXPOSURE CAN CAUSE:
NAUSEA, HEADACHE AND VOMITING
CONFUSION
WEAKNESS
DROWSINESS
UNCONSCIOUSNESS
ATAXIA
CONJUNCTIVITIS
BLURRED VISION
TEARING
CHRONIC EFFECTS
TARGET ORGAN(S):
LIVER
KIDNEYS
BLOOD
RTECS #: BX0350000
ANILINE, M-CHLORO-
TOXICITY DATA
ORL-RAT LD50:256 MG/KG GISAAA 31(12),6,1966
IHL-RAT LD50:150 PPM/4H NTIS** OTS0555316
SKN-RAT LD50:250 MG/KG 85GMAT -,34,1982
IPR-RAT LD50:200 MG/KG TSCAT* OTS 206512
ORL-MUS LD50:334 MG/KG GTPZAB 13(5),29,1969
IHL-MUS LC50:550 MG/M3/4H 85GMAT -,34,1982
IPR-MUS LD50:200 MG/KG TSCAT* OTS 206512
SKN-CAT LD50:223 MG/KG GTPZAB 13(5),29,1969
ORL-GPG LD50:250 MG/KG GISAAA 31(12),6,1966
SKN-GPG LD50:100 MG/KG TSCAT* OTS 206512
TARGET ORGAN DATA
SENSE ORGANS AND SPECIAL SENSES (MYDRIASIS)
BEHAVIORAL (CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD)
LUNGS, THORAX OR RESPIRATION (CYANOSIS)
LUNGS, THORAX OR RESPIRATION (OTHER CHANGES)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A
CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT FLUKA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
EC INDEX NO: 612-010-00-8
TOXIC
R 23/24/25
Page 3
PRODUCT #: 23320 NAME: 3-CHLOROANILINE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Tuesday, March 11, 1903 9:41AM
TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
R 33
DANGER OF CUMULATIVE EFFECTS.
S 28
AFTER CONTACT WITH SKIN, WASH IMMEDIATELY WITH PLENTY OF WATER.
S 36/37
WEAR SUITABLE PROTECTIVE CLOTHING AND GLOVES.
S 45
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
NOES 1983: HZD X4029; NIS 1; TNF 17; NOS 1; TNE 851; TFE 187
EPA GENETOX PROGRAM 1988, NEGATIVE: SPERM MORPHOLOGY-MOUSE
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
EPA TSCA 8(A) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE
FEREAC 47,26992,82
EPA TSCA SECTION 8(D) UNPUBLISHED HEALTH/SAFETY STUDIES
EPA TSCA SECTION 8(E) RISK NOTIFICATION, 8EHQ-0193-8687
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, APRIL 1997
NTP CARCINOGENESIS STUDIES; TEST COMPLETED (PEER REVIEW), APRIL 1997
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1997 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC.,
FLUKA CHEMIE AG
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
Page 4
|