PRODUCT #: D6379 NAME: M-DINITROBENZENE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Friday, March 07, 1903 4:09PM
Sigma Chemical Co. Aldrich Chemical Co., Inc. Fluka Chemical Corp.
P.O. Box 14508 1001 West St. Paul 1001 West St. Paul
St. Louis, MO 63178 Milwaukee, WI 53233 Milwaukee, WI 53233
Phone: 314-771-5765 Phone: 414-273-3850 Phone: 414-273-3850
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CATALOG #: D6379
NAME: M-DINITROBENZENE
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 99-65-0
MF: C6H4N2O4
EC NO: 202-776-8
SYNONYMS
BENZENE, 1,3-DINITRO- * BINITROBENZENE * M-DINITROBENZENE * 1,3-
DINITROBENZENE * 2,4-DINITROBENZENE * M-DINITROBENZENE (ACGIH:DOT:
OSHA) * 1,3-DINITROBENZOL * DWUNITROBENZEN (POLISH) * UN1597 (DOT) *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
HIGHLY TOXIC (USA)
VERY TOXIC (EU)
HEATING MAY CAUSE AN EXPLOSION.
VERY TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
DANGER OF CUMULATIVE EFFECTS.
POSSIBLE RISK OF IRREVERSIBLE EFFECTS.
POSSIBLE MUTAGEN.
REPRODUCTIVE HAZARD.
TARGET ORGAN(S):
BLOOD
LIVER
MAY BE SHOCK-SENSITIVE.
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
DO NOT BREATHE DUST.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES.
ASSURE ADEQUATE FLUSHING OF THE EYES BY SEPARATING THE EYELIDS
WITH FINGERS.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN.
DISCARD CONTAMINATED CLOTHING AND SHOES.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
WATER SPRAY.
CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
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PRODUCT #: D6379 NAME: M-DINITROBENZENE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Friday, March 07, 1903 4:09PM
THIS MATERIAL, LIKE MOST MATERIALS IN POWDER FORM, IS CAPABLE OF
CREATING A DUST EXPLOSION.
MAY EXPLODE WHEN HEATED.
MAY BE SHOCK-SENSITIVE.
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.
AVOID RAISING DUST.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
CHEMICAL SAFETY GOGGLES.
WEAR HEAVY RUBBER GLOVES.
NIOSH/MSHA-APPROVED RESPIRATOR.
USE ONLY IN A CHEMICAL FUME HOOD.
RUBBER APRON.
DO NOT BREATHE DUST.
DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
READILY ABSORBED THROUGH SKIN.
WASH THOROUGHLY AFTER HANDLING.
HIGHLY TOXIC.
POSSIBLE MUTAGEN.
REPRODUCTIVE HAZARD.
KEEP TIGHTLY CLOSED.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
ORANGE POWDER
PHYSICAL PROPERTIES
BOILING POINT: 297 C
MELTING POINT: 88 C TO 90 C
SPECIFIC GRAVITY: 1.368
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
INCOMPATIBILITIES
OXIDIZING AGENTS
REDUCING AGENTS
STRONG BASES
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
THERMAL DECOMPOSITION MAY PRODUCE CARBON MONOXIDE, CARBON DIOXIDE,
AND NITROGEN OXIDES.
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
MAY BE FATAL IF INHALED, SWALLOWED, OR ABSORBED THROUGH SKIN.
MAY CAUSE IRRITATION.
ABSORPTION INTO THE BODY LEADS TO THE FORMATION OF METHEMOGLOBIN
WHICH IN SUFFICIENT CONCENTRATION CAUSES CYANOSIS. ONSET MAY BE
DELAYED 2 TO 4 HOURS OR LONGER.
SYMPTOMS OF EXPOSURE MAY INCLUDE BURNING SENSATION, COUGHING,
WHEEZING, LARYNGITIS, SHORTNESS OF BREATH, HEADACHE, NAUSEA AND
VOMITING.
CHRONIC EFFECTS
LABORATORY EXPERIMENTS HAVE SHOWN MUTAGENIC EFFECTS.
MAY CAUSE REPRODUCTIVE DISORDERS.
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PRODUCT #: D6379 NAME: M-DINITROBENZENE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Friday, March 07, 1903 4:09PM
TARGET ORGAN(S):
BLOOD
LIVER
RTECS #: CZ7350000
BENZENE, M-DINITRO-
IRRITATION DATA
EYE-RBT 100 MG ATDAEI 1,168,1992
TOXICITY DATA
ORL-HMN LDLO:28 MG/KG 34ZIAG -,226,1969
ORL-RAT LD50:59500 UG/KG ATDAEI 1,168,1992
IPR-RAT LD50:28 MG/KG AEPPAE 207,446,1949
ORL-MUS LD50:74700 UG/KG ATDAEI 1,168,1992
IVN-DOG LD50:10 MG/KG NTIS** AD-A066-307
SKN-RBT LD50:1900 MG/KG ATDAEI 1,168,1992
ORL-BWD LD50:42 MG/KG TXAPA9 21,315,1972
TARGET ORGAN DATA
PERIPHERAL NERVE AND SENSATION (SPASTIC PARALYSIS WITH/WITHOUT SENSORY CH
BEHAVIORAL (SOMNOLENCE)
BEHAVIORAL (TREMOR)
BEHAVIORAL (CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD)
BEHAVIORAL (CHANGE IN MOTOR ACTIVITY)
BEHAVIORAL (COMA)
LUNGS, THORAX OR RESPIRATION (DYSPNAE)
LUNGS, THORAX OR RESPIRATION (CYANOSIS)
LUNGS, THORAX OR RESPIRATION (RESPIRATORY STIMULATION)
BLOOD (OTHER HEMOLYSIS WITH OR WITHOUT ANEMIA)
BLOOD (METHEMOGLOBINEMIA-CARBOXHEMOGLOBINEMIA)
SKIN AND APPENDAGES (HAIR)
PATERNAL EFFECTS (SPERMATOGENESIS)
PATERNAL EFFECTS (TESTES, EPIDIDYMIS, SPERM DUCT)
MATERNAL EFFECTS (OVARIES, FALLOPIAN TUBES)
EFFECTS ON FERTILITY (MALE FERTILITY INDEX)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
CONTACT A LICENSED PROFESSIONAL WASTE DISPOSAL SERVICE TO DISPOSE OF
THIS MATERIAL.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
VERY TOXIC
R5
HEATING MAY CAUSE AN EXPLOSION.
R 26/27/28
VERY TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
R 33
DANGER OF CUMULATIVE EFFECTS.
R 40
POSSIBLE RISK OF IRREVERSIBLE EFFECTS.
S 45
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
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PRODUCT #: D6379 NAME: M-DINITROBENZENE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Friday, March 07, 1903 4:09PM
S 36/37/39
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
S 22
DO NOT BREATHE DUST.
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
ACGIH TLV-TWA 1.0 MG/M3 (0.15 PPM) (SKIN) DTLVS* TLV/BEI,1996
MSHA STANDARD-AIR:TWA 0.15 PPM (1 MG/M3) (SKIN)
DTLVS* 3,92,1971
OSHA PEL (GEN INDU):8H TWA 1 MG/M3 (SKIN)
CFRGBR 29,1910.1000,1994
OSHA PEL (CONSTRUC):8H TWA 1 MG/M3 (SKIN)
CFRGBR 29,1926.55,1994
OSHA PEL (SHIPYARD):8H TWA 1 MG/M3 (SKIN)
CFRGBR 29,1915.1000,1993
OSHA PEL (FED CONT):8H TWA 1 MG/M3 (SKIN)
CFRGBR 41,50-204.50,1994
NIOSH REL TO M-DINITROBENZENE-AIR:10H TWA 1 MG/M3 (SK)
NIOSH* DHHS #92-100,1992
NOHS 1974: HZD 27046; NIS 2; TNF 184; NOS 3; TNE 1754
NOES 1983: HZD 27046; NIS 2; TNF 41; NOS 4; TNE 2489; TFE 1914
EPA GENETOX PROGRAM 1988, POSITIVE: HISTIDINE REVERSION-AMES TEST
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
ON EPA IRIS DATABASE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, APRIL 1997
U.S. INFORMATION
THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS.
CALIFORNIA PROPOSITION 65:
THIS PRODUCT IS OR CONTAINS CHEMICAL(S) KNOWN TO THE STATE OF
CALIFORNIA TO CAUSE MALE REPRODUCTIVE TOXICITY.
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1997 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC.,
FLUKA CHEMIE AG
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
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