PRODUCT #: 01640 NAME: ACRIDINE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Monday, March 10, 1903 8:34AM
Sigma Chemical Co. Aldrich Chemical Co., Inc. Fluka Chemical Corp.
P.O. Box 14508 1001 West St. Paul 1001 West St. Paul
St. Louis, MO 63178 Milwaukee, WI 53233 Milwaukee, WI 53233
Phone: 314-771-5765 Phone: 414-273-3850 Phone: 414-273-3850
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CATALOG #: 01640
NAME: ACRIDINE
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 260-94-6
MF: C13H9N
EC NO: 205-971-6
SYNONYMS
ACRIDINE (DOT) * AKRIDIN (CZECH) * 9-AZAANTHRACENE * 10-AZAANTHRACENE
* BENZO(B)QUINOLINE * 2,3-BENZOQUINOLINE * COAL TAR PITCH VOLATILES:
ACRIDINE (OSHA) * DIBENZO(B,E)PYRIDINE * UN2713 (DOT) *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
HARMFUL
HARMFUL BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
CAUSES SEVERE IRRITATION.
LACHRYMATOR.
PHOTOSENSITIZER.
STERNUTATOR.
TARGET ORGAN(S):
NERVES
BLOOD
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
TAKE OFF IMMEDIATELY ALL CONTAMINATED CLOTHING.
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
DO NOT BREATHE DUST.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES.
ASSURE ADEQUATE FLUSHING OF THE EYES BY SEPARATING THE EYELIDS
WITH FINGERS.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN.
WASH CONTAMINATED CLOTHING BEFORE REUSE.
DISCARD CONTAMINATED SHOES.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
WATER SPRAY.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
Page 1
PRODUCT #: 01640 NAME: ACRIDINE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Monday, March 10, 1903 8:34AM
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
EVACUATE AREA.
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
WEAR DISPOSABLE COVERALLS AND DISCARD THEM AFTER USE.
SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.
AVOID RAISING DUST.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT
GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.
USE ONLY IN A CHEMICAL FUME HOOD.
SAFETY SHOWER AND EYE BATH.
FACESHIELD (8-INCH MINIMUM).
DO NOT BREATHE DUST.
DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
KEEP TIGHTLY CLOSED.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
YELLOW POWDER
PHYSICAL PROPERTIES
MELTING POINT: 106 TO 109C
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
INCOMPATIBILITIES
STRONG OXIDIZING AGENTS
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
TOXIC FUMES OF:
CARBON MONOXIDE, CARBON DIOXIDE
NITROGEN OXIDES
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN.
CAUSES SEVERE IRRITATION.
HIGH CONCENTRATIONS ARE EXTREMELY DESTRUCTIVE TO TISSUES OF THE MUCOUS
MEMBRANES AND UPPER RESPIRATORY TRACT, EYES AND SKIN.
SYMPTOMS OF EXPOSURE MAY INCLUDE BURNING SENSATION, COUGHING,
WHEEZING, LARYNGITIS, SHORTNESS OF BREATH, HEADACHE, NAUSEA AND
VOMITING.
CAUSES SNEEZING. DO NOT INHALE.
CAUSES PHOTOSENSITIVITY. EXPOSURE TO LIGHT CAN RESULT IN ALLERGIC
REACTIONS RESULTING IN DERMATOLOGIC LESIONS, WHICH CAN VARY FROM
SUNBURNLIKE RESPONSES TO EDEMATOUS, VESICULATED LESIONS OR BULLAE.
ABSORPTION INTO THE BODY LEADS TO THE FORMATION OF METHEMOGLOBIN
WHICH IN SUFFICIENT CONCENTRATION CAUSES CYANOSIS. ONSET MAY BE
DELAYED 2 TO 4 HOURS OR LONGER.
EXPOSURE CAN CAUSE:
DAMAGE TO THE EYES
TARGET ORGAN(S):
NERVES
BLOOD
EYES
TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND
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PRODUCT #: 01640 NAME: ACRIDINE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Monday, March 10, 1903 8:34AM
TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
RTECS #: AR7175000
ACRIDINE
TOXICITY DATA
ORL-RAT LD50:2 GM/KG GTPZAB 14(9),56,1970
ORL-MUS LD50:500 MG/KG GTPZAB 14(9),56,1970
SCU-MUS LD50:400 MG/KG BJEPA5 28,1,1947
IVN-RBT LD50:100 MG/KG BJEPA5 28,1,1947
TARGET ORGAN DATA
SENSE ORGANS AND SPECIAL SENSES (LACRIMATION)
BEHAVIORAL (SOMNOLENCE)
BEHAVIORAL (EXCITEMENT)
GASTROINTESTINAL (NECROTIC CHANGES)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A
CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT FLUKA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
HARMFUL
R 20/21/22
HARMFUL BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
S 26
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
S 27
TAKE OFF IMMEDIATELY ALL CONTAMINATED CLOTHING.
S 36/37/39
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
S 22
DO NOT BREATHE DUST.
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
OSHA PEL (GEN INDU):8H TWA 0.2 MG/M3
CFRGBR 29,1910.1000,1994
OSHA PEL (CONSTRUC):8H TWA 0.2 MG/M3
CFRGBR 29,1926.55,1994
OSHA PEL (SHIPYARD):8H TWA 0.2 MG/M3
CFRGBR 29,1915.1000,1993
OSHA PEL (FED CONT):8H TWA 0.2 MG/M3
CFRGBR 41,50-204.50,1994
NOHS 1974: HZD 03490; NIS 1; TNF 17; NOS 1; TNE 34
NOES 1983: HZD 03490; NIS 1; TNF 7; NOS 3; TNE 70
EPA GENETOX PROGRAM 1988, INCONCLUSIVE: S CEREVISIAE-FORWARD MUTATION
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
EPA TSCA SECTION 8(D) UNPUBLISHED HEALTH/SAFETY STUDIES
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, APRIL 1997
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
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PRODUCT #: 01640 NAME: ACRIDINE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Monday, March 10, 1903 8:34AM
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1997 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC.,
FLUKA CHEMIE AG
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
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