Page 1/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 03/18/2008 Reviewed on 06/25/2007
1 Identification of substance:
路 Product name: PhosFlow Fix Buffer I
路 Catalog number: 557870
路 Manufacturer/Supplier:
BD Biosciences, Pharmingen
10975 Torreyana Road
San Diego, CA 92121-1106
Tel. (877)232-8995
路 Information department: Technical Services
路 Emergency information:
In case of a chemical emergency, spill, fire, exposure, or accident please call ChemTrec at (800)424-9300 or 911
2 Composition/Data on components:
路 Chemical characterization
路 Description: Mixture of the substances listed below with nonhazardous additions.
路 Dangerous components:
30525-89-4 paraformaldehyde Xn, Xi; R 20/22-36/37/38-40-43 4.0%
3 Hazards identification
路 Hazard description:
Xn Harmful
路 Information pertaining to particular dangers for man and environment
R 40 Limited evidence of a carcinogenic effect.
R 43 May cause sensitization by skin contact.
路 Classification system
The classification was made according to the latest editions of international substances lists, and expanded upon
from company and literature data.
路 NFPA ratings (scale 0-4)
Health = 2
0 Fire = 0
2 0 Reactivity = 0
4 First aid measures
路 General information No special measures required.
路 After inhalation
Supply fresh air and seek medical advice.
In case of unconsciousness place patient on side position for transportation.
路 After skin contact Immediately wash with water and soap and rinse thoroughly.
路 After eye contact Rinse opened eye for 15 minutes under running water. Then consult a doctor.
路 After swallowing Seek immediate medical advice.
(Contd. on page 2)
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Page 2/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 03/18/2008 Reviewed on 06/25/2007
Product name: PhosFlow Fix Buffer I
(Contd. of page 1)
路 Information for doctor Show the product label or this MSDS.
5 Fire fighting measures
路 Suitable extinguishing agents
CO2, ABC multipurpose dry chemical or water spray. Fight larger fires with water spray or alcohol resistant
foam.
路 Protective equipment: No special measures required.
6 Accidental release measures
路 Person-related safety precautions: Not required.
路 Measures for environmental protection: Wipe up with damp sponge or mop.
路 Measures for cleaning/collecting:
Dispose contaminated material as waste according to item 13.
Ensure adequate ventilation.
路 Additional information:
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
7 Handling and storage
路 Handling
路 Information for safe handling: Ensure good ventilation/exhaustion at the workplace.
路 Information about protection against explosions and fires: No special measures required.
路 Storage
路 Requirements to be met by storerooms and receptacles: 4 C
路 Information about storage in one common storage facility: Store away from oxidizing agents.
路 Further information about storage conditions: Store in cool, dry conditions in well sealed containers.
8 Exposure controls and personal protection
路 Additional information about design of technical systems: No further data; see item 7.
路 Components with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be monitored at
the workplace.
路 Additional information: The lists that were valid during the creation were used as basis.
路 Personal Protective Equipment
路 General protective and hygienic measures
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
路 Breathing equipment:
In case of brief exposure, use a chemical fume hood or a NIOSH/MSHA-approved respirator.
(Contd. on page 3)
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Page 3/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 03/18/2008 Reviewed on 06/25/2007
Product name: PhosFlow Fix Buffer I
(Contd. of page 2)
路 Protection of hands:
Chemical resistant gloves (i.e. nitrile, or equivalent).
路 Eye protection: Safety glasses
路 Body protection: Protective work clothing (lab coat).
9 Physical and chemical properties:
路 General Information
Liquid
Form:
Clear
Color:
Characteristic
Odor:
路 Change in condition
Melting point/Melting range: Not determined
Boiling point/Boiling range: Not determined
Not applicable
路 Flash point:
Product is not self igniting.
路 Auto igniting:
Product does not present an explosion hazard.
路 Danger of explosion:
Not applicable
路 Vapor pressure:
Not determined
路 Density:
路 Solubility in / Miscibility with
Soluble
Water:
Not applicable
路 pH-value:
10 Stability and reactivity
路 Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
路 Materials to be avoided: Incompatible material: strong oxidizers.
路 Dangerous reactions No dangerous reactions known
路 Dangerous products of decomposition: No dangerous decomposition products known.
11 Toxicological information
路 Acute toxicity:
路 LD/LC50 values that are relevant for classification:
30525-89-4 paraformaldehyde
Oral LD50 592 mg/kg (rat)
Dermal LD50 500 mg/kg (rbt)
(Contd. on page 4)
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Page 4/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 03/18/2008 Reviewed on 06/25/2007
Product name: PhosFlow Fix Buffer I
(Contd. of page 3)
路 Primary irritant effect:
路 on the skin: No irritating effect.
路 on the eye: No irritating effect.
路 Sensitization: No sensitizing effects known.
路 Additional toxicological information:
The product shows the following dangers according to internally approved calculation methods for preparations:
Irritant
California Proposition 65 - Warning: This product was sterilized with ethylene oxide, and is known to the State of
California to cause cancer.
12 Ecological information:
路 Ecotoxical effects:
路 Other information:
The ecological effects have not been thoroughly investigated, but currently none have been identified.
路 General notes: Water danger class 3 (Self-assessment): extremely hazardous for water.
13 Disposal considerations
路 Product:
路 Recommendation
Must not be disposed of with solid waste.
Dispose of material in accordance with federal (40 CFR 261), state and local requirements.
This product is not considered a RCRA hazardous waste.
路 Uncleaned packagings:
路 Recommendation: Disposal must be made according to state and federal regulations.
路 Recommended cleansing agent: Water, if necessary with cleansing agents.
14 Transport information
路 Maritime transport IMDG:
路 Marine pollutant: No
15 Regulations
路 SARA Section 355 (extremely hazardous substances)
30525-89-4 paraformaldehyde
路 SARA Section 313 (specific toxic chemical listings)
30525-89-4 paraformaldehyde
路 TSCA (Toxic Substances Control Act)
30525-89-4 paraformaldehyde
(Contd. on page 5)
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 03/18/2008 Reviewed on 06/25/2007
Product name: PhosFlow Fix Buffer I
(Contd. of page 4)
路 California Proposition 65 - Chemicals known to cause cancer
Formaldehyde is toxic, allergenic, and is known to the state of
California to cause cancer. Note: Formaldehyde poses a cancer threat through inhalation of the gas or vapor.
Forseeable use of this product does not pose a known cancer threat, since it contains paraformaldehyde and in
the liquid, not gaseous form.
30525-89-4 paraformaldehyde
路 Chemicals known to cause reproductive toxicity for females:
None of the ingredients is listed.
路 Chemicals known to cause reproductive toxicity for males:
None of the ingredients is listed.
路 Chemicals known to cause developmental toxicity:
None of the ingredients is listed.
路 Carcinogenicity categories
路 IARC (International Agency for Research on Cancer)
None of the ingredients is listed.
路 NTP (National Toxicology Program)
None of the ingredients is listed.
路 TLV (Threshold Limit Value established by ACGIH)
None of the ingredients is listed.
路 Product related hazard information:
The product has been classified and marked in accordance with regulations on hazardous materials.
路 Hazard symbols:
Xn Harmful
路 Hazard-determining components of labeling:
paraformaldehyde
路 Risk phrases:
40 Limited evidence of a carcinogenic effect.
43 May cause sensitization by skin contact.
路 Safety phrases:
2 Keep out of the reach of children.
13 Keep away from food, drink and animal feedingstuffs.
36/37 Wear suitable protective clothing and gloves.
46 If swallowed, seek medical advice immediately and show this container or label.
路 National regulations
路 Technical instructions (air):
Class Share in %
NK 4.0
路 Water hazard class: Water danger class 3 (Self-assessment): extremely hazardous for water.
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(Contd. on page 6)
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 03/18/2008 Reviewed on 06/25/2007
Product name: PhosFlow Fix Buffer I
(Contd. of page 5)
16 Other information:
To the best of our knowledge, the information contained herein is accurate. However, neither Becton,Dickinson
and Company or any of its subsidiaries assumes any liabilities whatsoever for the accuracy or completeness of
the information contained herein. Final determination of suitability of any material is the sole responsibility of
the user. All materials may present unknown hazards and should be used with caution. Although certain hazards
are described herein, we cannot guarantee that these are the only hazards that exist.
路 Department issuing MSDS: Safety and Environment Department
路 Contact: Technical Service Representative
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