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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 02/26/2008 Reviewed on 02/26/2008
1 Identification of substance:
路 Product name: Human Liver Microsomes
路 Catalog number:
452001, 452002, 452003, 452009, 452013, 452024, 452025, 452035, 452037, 452040, 452047, 452054, 452056,
452061, 452069, 452074, 452088, 452091, 452093, 452095, 452103, 452113, 452131, 452132, 452133, 452134,
452135, 452136, 452137, 452138, 452141, 452142, 452143, 452144, 452161, 452165, 452172, 452183
路 Manufacturer/Supplier:
BD Biosciences - Discovery Labware
6 Henshaw Street
Woburn, MA 01801
Tel: 877.232.8995
路 Information department: Technical Services
路 Emergency information:
In case of a chemical emergency, spill, fire, exposure, or accident contact BD Discovery Labware at
800.334.5229, or ChemTrec at 800.424.9300.
2 Composition/Data on components:
路 Chemical characterization
路 Description: Mixture of the substances listed below with nonhazardous additions.
路 Dangerous components: Void
3 Hazards identification
路 Hazard description:
This product contains no hazardous constituents, or the concentration of all chemical constituents are below the
regulatory threshold limits described by Occupational Safety Health Administration Hazard Communication
Standard 29 CFR 1910.1200 and the European Directive 91/155/EEC, and 93/112/EC.
路 Classification system
The classification was made according to the latest editions of international substances lists, and expanded upon
from company and literature data.
路 NFPA ratings (scale 0-4)
Health = 0
0 Fire = 0
0 0 Reactivity = 0
路 Additional information:
This product contains human blood, human blood products or other potentially infectious materials. Use
universal precautions when handling.
4 First aid measures
路 After inhalation Seek medical treatment in case of complaints.
路 After skin contact Immediately wash with water and soap and rinse thoroughly.
路 After eye contact Rinse opened eye for 15 minutes under running water. Then consult a doctor.
路 After swallowing Seek immediate medical advice.
(Contd. on page 2)
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 02/26/2008 Reviewed on 02/26/2008
Product name: Human Liver Microsomes
(Contd. of page 1)
路 Information for doctor Show the product label or this MSDS.
5 Fire fighting measures
路 Suitable extinguishing agents
CO2, ABC multipurpose dry chemical or water spray. Fight larger fires with water spray or alcohol resistant
foam.
路 Protective equipment: No special measures required.
6 Accidental release measures
路 Person-related safety precautions: Not required.
路 Measures for environmental protection: Wipe up with damp sponge or mop.
路 Measures for cleaning/collecting:
Absorb spills using disposable towels or absorbant material. Wear gloves during spill cleanup. Disinfect area
with bleach (hypochlorite solution) for at least 15 minutes, or an approved discinfectant for labeled contact time,
then wipe clean. Contain absorbant waste in biohazardous bag.
7 Handling and storage
路 Handling
路 Information for safe handling: Prevent formation of aerosols.
路 Information about protection against explosions and fires: No special measures required.
路 Storage
路 Requirements to be met by storerooms and receptacles: -80 C
路 Information about storage in one common storage facility: Store away from oxidizing agents.
路 Further information about storage conditions: None.
8 Exposure controls and personal protection
路 Additional information about design of technical systems: No further data; see item 7.
路 Components with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be monitored at
the workplace.
路 Additional information: The lists that were valid during the creation were used as basis.
路 Personal Protective Equipment
路 General protective and hygienic measures
The usual precautionary measures for handling chemicals should be followed.
路 Breathing equipment: Not required.
路 Protection of hands:
Chemical resistant gloves (i.e. nitrile, or equivalent).
(Contd. on page 3)
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 02/26/2008 Reviewed on 02/26/2008
Product name: Human Liver Microsomes
(Contd. of page 2)
路 Eye protection: Safety glasses
路 Body protection: Protective work clothing (lab coat).
9 Physical and chemical properties:
路 General Information
Liquid
Form:
Frozen
Brown
Color:
Characteristic
Odor:
Undetermined
路 Change in condition
路 Melting point/Melting range: Not determined
路 Boiling point/Boiling range: Not determined
Not applicable
路 Flash point:
Product is not self igniting.
路 Auto igniting:
Product does not present an explosion hazard.
路 Danger of explosion:
Not applicable
路 Vapor pressure:
Not determined
路 Density:
路 Solubility in / Miscibility with
Not miscible or difficult to mix
Water:
Not applicable
路 pH-value:
路 Solvent content:
0.0 %
Organic solvents:
10 Stability and reactivity
路 Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
路 Materials to be avoided: Incompatible material: strong oxidizers.
路 Dangerous reactions No dangerous reactions known
路 Dangerous products of decomposition: No dangerous decomposition products known.
11 Toxicological information
路 Acute toxicity:
路 Primary irritant effect:
路 on the skin: No irritating effect.
路 on the eye: No irritating effect.
路 Sensitization: No sensitizing effects known.
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 02/26/2008 Reviewed on 02/26/2008
Product name: Human Liver Microsomes
(Contd. of page 3)
路 Additional toxicological information:
This product contains human tissue, a potential biohazardous material. Use universal precautions when
handling. Handle as if product were capable of transmitting disease. Material used in this product has been
tested using FDA approved methods and found negative for Human Immunodeficiency Virus (HIV-1/HIV-2), HT
Cell Leukemia Virus (HTLV-1/HTLV-2), Hepatitis B Virus (HBV), antibody to Hepatitis C Virus (HCV), and
Cytomegalo Virus (CMV). However, no known test method can offer complete assurance that specimens of
human origin will not transmit infectious disease. When handling or disposing, follow precautions decribed in
CDC and FDA recommendations and OSHA Bloodborne Pathogen recommendations.
The product is not subject to OSHA classification according to internally approved calculation methods for
preparations.
When used and handled according to specifications, the product does not have any harmful effects according to
our experience and the information provided to us.
This product contains, a potential biohazardous material. Use universal precautions when handling. Handle as if
product were capable of transmitting disease. Material used in this product has been tested using approved
methods and has been found negative for infectious diseases. However, no known test method can offer complete
assurance that specimens of human origin will not transmit infectious disease. When handling or disposing,
follow precautions decribed in CDC, OSHA Bloodborne Pathogen recommendations, and the European Directive
90/679/EC.
12 Ecological information:
路 Ecotoxical effects:
路 Other information:
The ecological effects have not been thoroughly investigated, but currently none have been identified.
路 General notes: Water hazard class 1 (Self-assessment): slightly hazardous for water.
13 Disposal considerations
路 Product:
路 Recommendation
After the product is used, disinfect with bleach (sodium hypochlorite),
or an approved discinfectant, or incinerate, or autoclave at 121 C for at least 15 minutes before disposing.
Smaller quantities can be disposed of with solid waste.
This product is not considered a RCRA hazardous waste.
Dispose of material in accordance with federal (40 CFR 261), state and local requirements.
路 Uncleaned packagings:
路 Recommendation: Disposal must be made according to state and federal regulations.
路 Recommended cleansing agent: Water, if necessary with cleansing agents.
14 Transport information
路 DOT regulations:
-
路 Hazard class:
路 Land transport ADR/RID (cross-border)
路 ADR/RID class: -
(Contd. on page 5)
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 02/26/2008 Reviewed on 02/26/2008
Product name: Human Liver Microsomes
(Contd. of page 4)
路 Maritime transport IMDG:
-
路 IMDG Class:
路 Marine pollutant: No
路 Air transport ICAO-TI and IATA-DGR:
路 ICAO/IATA Class: -
路 Transport/Additional information:
If a dashed line appears in the Hazard Class section for the type of transportation, this indicates the product is
not regulated for transportation. However, if a Hazard Class Number is listed the product is regulated.
15 Regulations
路 SARA Section 355 (extremely hazardous substances)
None of the ingredients is listed.
路 SARA Section 313 (specific toxic chemical listings)
None of the ingredients is listed.
路 TSCA (Toxic Substances Control Act)
57-50-1 sucrose
路 California Proposition 65 - Chemicals known to cause cancer
None of the ingredients is listed.
路 Chemicals known to cause reproductive toxicity for females:
None of the ingredients is listed.
路 Chemicals known to cause reproductive toxicity for males:
None of the ingredients is listed.
路 Chemicals known to cause developmental toxicity:
None of the ingredients is listed.
路 Carcinogenicity categories
路 IARC (International Agency for Research on Cancer)
None of the ingredients is listed.
路 NTP (National Toxicology Program)
None of the ingredients is listed.
路 TLV (Threshold Limit Value established by ACGIH)
57-50-1 sucrose A4
路 Product related hazard information:
Observe the general safety regulations when handling chemicals
The product is not subject to identification regulations pertaining to regulations on hazardous materials.
路 National regulations
路 Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 02/26/2008 Reviewed on 02/26/2008
Product name: Human Liver Microsomes
(Contd. of page 5)
16 Other information:
To the best of our knowledge, the information contained herein is accurate. However, neither Becton,Dickinson
and Company or any of its subsidiaries assumes any liabilities whatsoever for the accuracy or completeness of
the information contained herein. Final determination of suitability of any material is the sole responsibility of
the user. All materials may present unknown hazards and should be used with caution. Although certain hazards
are described herein, we cannot guarantee that these are the only hazards that exist.
路 Department issuing MSDS: Safety and Environment Department
路 Contact: Technical Service Representative
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