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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 07/09/2008 Reviewed on 07/09/2008
1 Identification of substance:
路 Product name: BD Matrigel鈩? Basement Membrane Matrix
路 Catalog number: 354230, 354234, 354277, 356230, 356231, 356234, 356235, 356237
路 Manufacturer/Supplier:
BD Biosciences - Discovery Labware
2 Oak Park
Bedford, MA 01730
Tel: 877.232.8995
路 Information department: For further information, please call Technical Services at (877)232-8995
路 Emergency information:
In case of a chemical emergency, spill, fire, exposure, or accident contact BD Discovery Labware at
800.334.5229, or ChemTrec at 800.424.9300.
2 Composition/Data on components:
路 Chemical characterization
路 Description: Mixture of the substances listed below with nonhazardous additions.
路 Dangerous components: Chloroform 鈮? 0.0175%
路 CAS NO. Description %
chloroform Carc. Cat. 3; Xn, Xi; R 22-38-40-48/20/22
Danger: Flame 2.6/2
Warning: Health hazard 3.6/2, 3.9/2; Exclamation mark 3.1.O/4, 3.2/2
3 Hazards identification
路 Hazard description:
Xn Harmful
路 Information pertaining to particular dangers for man and environment
R 22 Harmful if swallowed.
R 36/37/38 Irritating to eyes, respiratory system and skin.
R 40 Limited evidence of a carcinogenic effect.
路 Classification system
The classification was made according to the latest editions of international substances lists, and expanded upon
from company and literature data.
路 NFPA ratings (scale 0-4)
Health = 1
0 Fire = 0
1 0 Reactivity = 0
路 GHS label elements
Warning
3.6/2 - Suspected of causing cancer.
(Contd. on page 2)
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Page 2/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 07/09/2008 Reviewed on 07/09/2008
Product name: BD Matrigel鈩? Basement Membrane Matrix
(Contd. of page 1)
路 Prevention:
Obtain special instructions before use.
Do not handle until all safety precautions have been read and understood.
Use personal protective equipment as required.
路 Response:
IF exposed or concerned: Get medical advice/attention.
路 Disposal:
Dispose of contents/container in accordance with local/regional/national/international regulations.
4 First aid measures
路 General information
Symptoms of poisoning may even occur after several hours; therefore provide medical observation for at least 48
hours after the accident.
路 After inhalation Supply fresh air; consult doctor in case of complaints.
路 After skin contact Immediately wash with water and soap and rinse thoroughly.
路 After eye contact Rinse opened eye for 15 minutes under running water. Then consult a doctor.
路 After swallowing Seek immediate medical advice.
路 Information for doctor Show the product label or this MSDS.
5 Fire fighting measures
路 Suitable extinguishing agents
CO2, ABC multipurpose dry chemical or water spray. Fight larger fires with water spray or alcohol resistant
foam.
路 Protective equipment: Use respiratory protective device.
6 Accidental release measures
路 Person-related safety precautions: Use respiratory protective device.
路 Measures for environmental protection: Wipe up with damp sponge or mop.
路 Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders).
Dispose contaminated material as waste according to item 13.
Ensure adequate ventilation.
路 Additional information:
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
7 Handling and storage
路 Handling
路 Information for safe handling: No special measures required.
路 Information about protection against explosions and fires: No special measures required.
(Contd. on page 3)
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Page 3/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 07/09/2008 Reviewed on 07/09/2008
Product name: BD Matrigel鈩? Basement Membrane Matrix
(Contd. of page 2)
路 Storage
路 Requirements to be met by storerooms and receptacles: -20潞 C
路 Information about storage in one common storage facility: Store away from oxidizing agents.
路 Further information about storage conditions: Store in cool, dry conditions in well sealed containers.
8 Exposure controls and personal protection
路 Additional information about design of technical systems: No further data; see item 7.
路 Components with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be monitored at
the workplace.
路 Additional information: The lists that were valid during the creation were used as basis.
路 Personal Protective Equipment
路 General protective and hygienic measures
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Avoid contact with the eyes and skin.
路 Breathing equipment:
In case of brief exposure, use a chemical fume hood or a NIOSH/MSHA-approved respirator.
路 Protection of hands:
Chemical resistant gloves (i.e. nitrile, or equivalent).
路 Eye protection: Safety glasses
路 Body protection: Protective work clothing (lab coat).
9 Physical and chemical properties:
路 General Information
Liquid
Form:
According to product specification
Color:
Characteristic
Odor:
路 Change in condition
Melting point/Melting range: Not determined
Boiling point/Boiling range: Not determined
Not applicable
路 Flash point:
Product is not self igniting.
路 Auto igniting:
Product does not present an explosion hazard.
路 Danger of explosion:
Not applicable
路 Vapor pressure:
(Contd. on page 4)
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Page 4/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 07/09/2008 Reviewed on 07/09/2008
Product name: BD Matrigel鈩? Basement Membrane Matrix
(Contd. of page 3)
Not determined
路 Density:
路 Solubility in / Miscibility with
Soluble
Water:
Not applicable
路 pH-value:
路 Solvent content:
鈮? 0.0175 %
Organic solvents:
10 Stability and reactivity
路 Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
路 Materials to be avoided: Incompatible material: strong oxidizers.
路 Dangerous reactions No dangerous reactions known
路 Dangerous products of decomposition: No dangerous decomposition products known.
11 Toxicological information
路 Acute toxicity:
路 Primary irritant effect:
路 on the skin: Irritant to skin and mucous membranes.
路 on the eye: Irritating effect.
路 Sensitization: No sensitizing effects known.
路 Additional toxicological information:
The product shows the following dangers according to internally approved calculation methods for preparations:
Harmful
Irritant
12 Ecological information:
路 General notes: Water hazard class 1 (Self-assessment): slightly hazardous for water.
13 Disposal considerations
路 Product:
路 Recommendation
Must not be disposed of with solid waste.
Dispose of material in accordance with federal (40 CFR 261), state and local requirements.
This product is not considered a RCRA hazardous waste.
路 Uncleaned packagings:
路 Recommendation: Disposal must be made according to state and federal regulations.
(Contd. on page 5)
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Page 5/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 07/09/2008 Reviewed on 07/09/2008
Product name: BD Matrigel鈩? Basement Membrane Matrix
(Contd. of page 4)
路 Recommended cleansing agent: Water, if necessary with cleansing agents.
14 Transport information
路 DOT regulations:
-
路 Hazard class:
路 Land transport ADR/RID (cross-border)
路 ADR/RID class: -
路 Maritime transport IMDG:
-
路 IMDG Class:
路 Marine pollutant: No
路 Air transport ICAO-TI and IATA-DGR:
路 ICAO/IATA Class: -
路 UN "Model Regulation": -
15 Regulations
路 SARA Section 355 (extremely hazardous substances)
None of the ingredients is listed.
路 SARA Section 313 (specific toxic chemical listings)
None of the ingredients is listed.
路 TSCA (Toxic Substances Control Act)
chloroform
路 California Proposition 65 - Chemicals known to cause cancer
chloroform
路 Chemicals known to cause reproductive toxicity for females:
None of the ingredients is listed.
路 Chemicals known to cause reproductive toxicity for males:
None of the ingredients is listed.
路 Chemicals known to cause developmental toxicity:
None of the ingredients is listed.
路 Carcinogenicity categories
路 IARC (International Agency for Research on Cancer)
chloroform 2B
路 NTP (National Toxicology Program)
chloroform R
路 TLV (Threshold Limit Value established by ACGIH)
chloroform A3
(Contd. on page 6)
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Page 6/6
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 07/09/2008 Reviewed on 07/09/2008
Product name: BD Matrigel鈩? Basement Membrane Matrix
(Contd. of page 5)
路 Product related hazard information:
The product has been classified and marked in accordance with regulations on hazardous materials.
路 Hazard symbols:
Xn Harmful
路 Hazard-determining components of labeling:
chloroform
路 Risk phrases:
22 Harmful if swallowed.
36/37/38 Irritating to eyes, respiratory system and skin.
40 Limited evidence of a carcinogenic effect.
路 Safety phrases:
24 Avoid contact with skin.
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
28 After contact with skin, wash immediately with plenty of water
路 National regulations
路 Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.
16 Other information:
To the best of our knowledge, the information contained herein is accurate. However, neither Becton,Dickinson
and Company or any of its subsidiaries assumes any liabilities whatsoever for the accuracy or completeness of
the information contained herein. Final determination of suitability of any material is the sole responsibility of
the user. All materials may present unknown hazards and should be used with caution. Although certain hazards
are described herein, we cannot guarantee that these are the only hazards that exist.
Use of Product:
- synthetic chemical for research only
- analytical standard
- must be handled by suitably qualified personnel
路 Department issuing MSDS: Safety and Environment Department
路 Contact: Technical Service Representative
路 Abbreviations and acronyms:
ADR: Accord europ茅en sur le transport des marchandises Dangereuses par Route (European Agreement concerning the International
Carriage of Dangerous Goods by Road)
RID: Reglement internationale concernent le transport des merchandises dangereuses par chemin de fer (Regulations Concerning the
International Transport of Dangerous Goods by Rail)
IMDG: International Maritime Code for Dangerous Goods
DOT: US Department of Transportation
IATA: International Air Transport Association
IATA-DGR: Dangerous Goods Regulations by the "International Air Transport Association" (IATA)
ICAO: International Civil Aviation Organization
ICAO-TI: Technical Instructions by the "International Civil Aviation Organization" (ICAO)
GHS: Globally Harmonized System of Classification and Labelling of Chemicals
ACGIH: American Conference of Governmental Industrial Hygienists
CAS: Chemical Abstracts Service (division of the American Chemical Society)
NFPA: National Fire Protection Association (USA)
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