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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 08/04/2004 Reviewed on 05/13/2004
1 Identification of substance:
路 Product name: Perm Buffer III
路 Catalog number: 558050
路 Manufacturer/Supplier:
BD Biosciences, Pharmingen
10975 Torreyana Road
San Diego, CA 92121-1106
Tel. (877)232-8995
路 Information department: Technical Services
路 Emergency information:
In case of a chemical emergency, spill, fire, exposure, or accident please call ChemTrec at (800)424-
9300 or 911
2 Composition/Data on components:
路 Chemical characterization
路 Description: Mixture consisting of the following components.
路 Dangerous components:
67-56-1 methanol 90.0%
3 Hazards identification
路 Hazard description:
T Toxic
F Highly flammable
路 Information pertaining to particular dangers for man and environment
R 11 Highly flammable.
R 23/24/25 Toxic by inhalation, in contact with skin and if swallowed.
R 39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin
and if swallowed.
路 Classification system
The classification was made according to the latest editions of international substances lists, and
expanded upon from company and literature data.
路 NFPA ratings (scale 0-4)
Health = 3
3 Fire = 3
3 0 Reactivity = 0
4 First aid measures
路 General information
Immediately remove contaminated clothing.
Remove breathing apparatus only after contaminated clothing have been completely removed.
In case of irregular breathing or respiratory arrest provide artificial respiration.
(Contd. on page 2)
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Page 2/7
Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 08/04/2004 Reviewed on 05/13/2004
Product name: Perm Buffer III
(Contd. of page 1)
路 After inhalation
Supply fresh air or oxygen; and immediately call for a doctor.
In case of unconsciousness place patient on side position for transportation.
路 After skin contact Immediately wash with water and soap and rinse thoroughly.
路 After eye contact Rinse opened eye for 15 minutes under running water. Then consult a doctor.
路 After swallowing Do not induce vomiting; immediately call for medical help.
路 Information for doctor Show this product label or this MSDS.
5 Fire fighting measures
路 Suitable extinguishing agents
CO2, ABC multipurpose dry chemical or water spray. Fight larger fires with water spray or alcohol
resistant foam.
路 Protective equipment: No special measures required.
6 Accidental release measures
路 Person-related safety precautions: Not required.
路 Measures for environmental protection: Wipe up with damp sponge or mop.
路 Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders).
Dispose contaminated material as waste according to item 13.
Ensure adequate ventilation.
路 Additional information:
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
7 Handling and storage
路 Handling
路 Information for safe handling:
Ensure good ventilation/exhaustion at the workplace.
Open and handle receptacle with care.
Prevent formation of aerosols.
路 Information about protection against explosions and fires:
Keep ignition sources away - Do not smoke.
Protect against electrostatic charges.
Keep respiratory protective device available.
路 Storage
路 Requirements to be met by storerooms and receptacles: 15 - 30 C
路 Information about storage in one common storage facility: Store away from oxidizing agents.
路 Further information about storage conditions: Store in cool, dry conditions in well sealed containers.
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(Contd. on page 3)
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 08/04/2004 Reviewed on 05/13/2004
Product name: Perm Buffer III
(Contd. of page 2)
8 Exposure controls and personal protection
路 Additional information about design of technical systems: No further data; see item 7.
路 Components with limit values that require monitoring at the workplace:
67-56-1 methanol
PEL 260 mg/m鲁, 200 ppm
REL Short-term value: 325 mg/m鲁, 250 ppm
Long-term value: 260 mg/m鲁, 200 ppm
Skin
TLV Short-term value: 328 mg/m鲁, 250 ppm
Long-term value: 262 mg/m鲁, 200 ppm
Skin; BEI
路 Additional information: The lists that were valid during the creation were used as basis.
路 Personal Protective Equipment
路 General protective and hygienic measures
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Store protective clothing separately.
Avoid contact with the eyes and skin.
路 Breathing equipment:
In case of brief exposure, use a chemical fume hood or a NIOSH/MSHA-approved respirator.
路 Protection of hands:
Chemical resistant gloves (i.e. nitrile, or equivalent).
路 Eye protection:
Safety glasses
Tightly sealed goggles.
路 Body protection: Protective work clothing (lab coat).
9 Physical and chemical properties:
路 General Information
Liquid
Form:
Clear
Color:
Odorless
Odor:
路 Change in condition
Melting point/Melting range: Not determined
Boiling point/Boiling range: 64掳C (147掳F)
11掳C (52掳F)
路 Flash point:
455.0掳C (851掳F)
路 Ignition temperature:
Product is not self igniting.
路 Auto igniting:
(Contd. on page 4)
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 08/04/2004 Reviewed on 05/13/2004
Product name: Perm Buffer III
(Contd. of page 3)
Product is not explosive. However, formation of explosive air/vapor
路 Danger of explosion:
mixtures are possible.
路 Explosion limits:
5.5 Vol %
Lower:
44.0 Vol %
Upper:
路 Vapor pressure at 20掳C (68掳F): 128.0 hPa (96 mm Hg)
Not applicable
0.811 g/cm鲁
路 Density at 20掳C (68掳F):
路 Solubility in / Miscibility with
Soluble
Water:
9.0
路 pH-value:
路 Solvent content:
90.0 %
Organic solvents:
10.0 %
Water:
10 Stability and reactivity
路 Thermal decomposition / conditions to be avoided:
No decomposition if used according to specifications.
路 Materials to be avoided: Incompatible material: strong oxidizers.
路 Dangerous reactions No dangerous reactions known
路 Dangerous products of decomposition: No dangerous decomposition products known.
11 Toxicological information
路 Acute toxicity:
路 LD/LC50 values that are relevant for classification:
67-56-1 methanol
Oral LD50 5628 mg/kg (rat)
路 Primary irritant effect:
路 on the skin: No irritating effect.
路 on the eye: No irritating effect.
路 Sensitization: No sensitizing effects known.
路 Additional toxicological information:
The product shows the following dangers according to internally approved calculation methods for
preparations:
Toxic
12 Ecological information:
路 Ecotoxical effects:
路 Other information:
The ecological effects have not been thoroughly investigated, but currently none have been identified.
(Contd. on page 5)
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 08/04/2004 Reviewed on 05/13/2004
Product name: Perm Buffer III
(Contd. of page 4)
路 General notes: Water hazard class 1 (Self-assessment): slightly hazardous for water.
13 Disposal considerations
路 Product:
路 Recommendation
Must not be disposed of with solid waste.
Dispose of material in accordance with federal (40 CFR 261), state and local requirements.
This product is not considered a RCRA hazardous waste.
路 Uncleaned packagings:
路 Recommendation: Disposal must be made according to state and federal regulations.
路 Recommended cleansing agent: Water, if necessary with cleansing agents.
14 Transport information
路 DOT regulations:
3
路 Hazard class:
路 Identification number: UN1230
II
路 Packing group:
路 Proper shipping name: METHANOL, solution
3+6.1
路 Label
路 Land transport ADR/RID (cross-border)
3 (FT1) Flammable liquids
路 ADR/RID class:
路 Danger code (Kemler): 336
1230
路 UN-Number:
II
路 Packaging group:
路 Description of goods: 1230 METHANOL, solution
路 Maritime transport IMDG:
3
路 IMDG Class:
1230
路 UN Number:
3+6.1
路 Label
II
路 Packaging group:
F-E,S-D
路 EMS Number:
(Contd. on page 6)
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 08/04/2004 Reviewed on 05/13/2004
Product name: Perm Buffer III
(Contd. of page 5)
No
路 Marine pollutant:
路 Proper shipping name: METHANOL, solution
路 Air transport ICAO-TI and IATA-DGR:
3
路 ICAO/IATA Class:
1230
路 UN/ID Number:
3+6.1
路 Label
II
路 Packaging group:
路 Proper shipping name: METHANOL, solution
15 Regulations
路 SARA Section 355 (extremely hazardous substances)
None of the ingredients is listed.
路 SARA Section 313 (specific toxic chemical listings)
67-56-1 methanol
路 TSCA (Toxic Substances Control Act)
67-56-1 methanol
路 California Proposition 65 - Chemicals known to cause cancer
None of the ingredients is listed.
路 California Proposition 65 - Chemicals known to cause reproductive toxicity
None of the ingredients is listed.
路 Carcinogenicity categories
路 IARC (International Agency for Research on Cancer)
None of the ingredients is listed.
路 NTP (National Toxicology Program)
None of the ingredients is listed.
路 TLV (Threshold Limit Value established by ACGIH)
None of the ingredients is listed.
路 Product related hazard information:
The product has been classified and marked in accordance with regulations on hazardous materials.
路 Hazard symbols:
T Toxic
F Highly flammable
路 Hazard-determining components of labeling:
methanol
路 Risk phrases:
11 Highly flammable.
(Contd. on page 7)
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Material Safety Data Sheet
acc. to ISO/DIS 11014
Printing date 08/04/2004 Reviewed on 05/13/2004
Product name: Perm Buffer III
(Contd. of page 6)
23/24/25 Toxic by inhalation, in contact with skin and if swallowed.
39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin
and if swallowed.
路 Safety phrases:
4 Keep away from living quarters.
7/9 Keep container tightly closed and in a well-ventilated place.
16 Keep away from sources of ignition - No smoking.
36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
45 In case of accident or if you feel unwell, seek medical advice immediately.
60 This material and its container must be disposed of as hazardous waste.
路 National regulations
路 Technical instructions (air):
Class Share in %
Water 10.0
I 90.0
16 Other information:
To the best of our knowledge, the information contained herein is accurate. However, neither
Becton,Dickinson and Company or any of its subsidiaries assumes any liabilities whatsoever for the
accuracy or completeness of the information contained herein. Final determination of suitability of any
material is the sole responsibility of the user. All materials may present unknown hazards and should be
used with caution. Although certain hazards are described herein, we cannot guarantee that these are
the only hazards that exist.
路 Department issuing MSDS: Safety and Environment Department
路 Contact: Technical Service Representative
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