PRODUCT #: 199931 NAME: SODIUM AZIDE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Thursday, March 20, 1903 3:08PM
Sigma Chemical Co. Aldrich Chemical Co., Inc. Fluka Chemical Corp.
P.O. Box 14508 1001 West St. Paul 1001 West St. Paul
St. Louis, MO 63178 Milwaukee, WI 53233 Milwaukee, WI 53233
Phone: 314-771-5765 Phone: 414-273-3850 Phone: 414-273-3850
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CATALOG #: 199931
NAME: SODIUM AZIDE
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 26628-22-8
EC NO: 247-852-1
SYNONYMS
AZIDE, SODIUM * AZOTURE DE SODIUM (FRENCH) * AZYDEK SODU (POLISH) *
KAZOE * NATRIUMAZID (GERMAN) * NATRIUMMAZIDE (DUTCH) * NCI-C06462 *
NEMAZYD * NSC 3072 * RCRA WASTE NUMBER P105 * SMITE * SODIUM AZIDE
(ACGIH:DOT) * SODIUM, AZOTURE DE (FRENCH) * SODIUM, AZOTURO DI
(ITALIAN) * U-3886 * UN1687 (DOT) *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
HIGHLY TOXIC (USA)
VERY TOXIC (EU)
MAY CAUSE HERITABLE GENETIC DAMAGE.
VERY TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
CONTACT WITH ACIDS LIBERATES VERY TOXIC GAS.
HEATING MAY CAUSE AN EXPLOSION.
READILY ABSORBED THROUGH SKIN.
AVOID CONTACT WITH METALS.
TARGET ORGAN(S):
NERVES
HEART
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
DO NOT BREATHE DUST.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN.
WASH CONTAMINATED CLOTHING BEFORE REUSE.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
DO NOT USE WATER.
DRY CHEMICAL POWDER.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
CONTAINER EXPLOSION MAY OCCUR UNDER FIRE CONDITIONS.
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
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PRODUCT #: 199931 NAME: SODIUM AZIDE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Thursday, March 20, 1903 3:08PM
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
EVACUATE AREA.
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.
AVOID RAISING DUST.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
ADDITIONAL INFORMATION
AZIDE REACTS WITH MANY HEAVY METALS SUCH AS LEAD, COPPER, MERCURY,
SILVER, GOLD TO FORM EXPLOSIVE COMPOUNDS. COPPER AND LEAD AZIDES ARE
MORE SENSITIVE THAN NITROGLYCERINE. AZIDE REACTS WITH METAL HALIDES
TO GIVE A RANGE OF METAL AZIDE HALIDES, MANY OF WHICH ARE EXPLOSIVE.
INCOMPATIBLE WITH CHROMYL CHLORIDE, HYDRAZINE, BROMINE, CARBON
DISULFIDE, DIMETHYL SULFATE, DIBROMOMALONITRILE.
AN EXPLOSION OCCURRED WHEN A MIXTURE OF SODIUM AZIDE, METHYLENE
CHLORIDE, DIMETHYL SULFOXIDE, AND SULFURIC ACID WERE BEING
CONCENTRATED ON A ROTARY EVAPORATOR.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT
GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.
USE ONLY IN A CHEMICAL FUME HOOD.
SAFETY SHOWER AND EYE BATH.
DO NOT BREATHE DUST.
DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
HIGHLY TOXIC.
MUTAGEN.
KEEP TIGHTLY CLOSED.
HEAT-SENSITIVE.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
SOLID.
PHYSICAL PROPERTIES
SPECIFIC GRAVITY: 1.850
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
INCOMPATIBILITIES
ACID CHLORIDES
HALOGENATED SOLVENTS
AVOID CONTACT WITH METALS.
AVOID CONTACT WITH ACID.
EXPLODES WHEN HEATED.
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
NITROGEN OXIDES
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
MAY BE FATAL IF INHALED, SWALLOWED, OR ABSORBED THROUGH SKIN.
MAY CAUSE EYE IRRITATION.
MAY CAUSE SKIN IRRITATION.
EXPOSURE CAN CAUSE:
NAUSEA, HEADACHE AND VOMITING
CHRONIC EFFECTS
MAY ALTER GENETIC MATERIAL.
TARGET ORGAN(S):
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PRODUCT #: 199931 NAME: SODIUM AZIDE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Thursday, March 20, 1903 3:08PM
NERVES, HEART
BRAIN
ADDITIONAL INFORMATION
LABORATORY EXPERIMENTS IN ANIMALS HAVE SHOWN SODIUM AZIDE TO PRODUCE
A PROFOUND HYPOTENSIVE EFFECT, DEMYELINATION OF MYELINATED NERVE
FIBERS IN THE CENTRAL NERVOUS SYSTEM, TESTICULAR DAMAGE, BLINDNESS,
ATTACKS OF RIGIDITY, HEPATIC AND CEREBRAL EFFECTS.
RTECS #: VY8050000
SODIUM AZIDE
TOXICITY DATA
ORL-WMN LDLO:786 MG/KG MTAEEB 4,219,1989
ORL-MAN LDLO:29 MG/KG MTAEEB 4,219,1989
ORL-MAN LDLO:129 MG/KG JATOD3 20,134,1996
ORL-WMN LDLO:14 MG/KG JFSCAS 35,193,1990
ORL-MAN LDLO:143 MG/KG JTCTDW 24,339,1986
ORL-RAT LD50:27 MG/KG FMCHA2 -,C32,1991
SCU-RAT LD50:45100 UG/KG MEPAAX 12,427,1961
ITR-RAT LD50:47500 UG/KG MEPAAX 12,427,1961
ORL-MUS LD50:27 MG/KG CLDND*
IPR-MUS LD50:28 MG/KG JIHTAB 30,98,1948
SCU-MUS LD50:23060 UG/KG MEPAAX 12,427,1961
IVN-MUS LD50:19 MG/KG CLDND*
UNR-MUS LD50:27 MG/KG BJCAAI 6,160,1952
SKN-RBT LD50:20 MG/KG FMCHA2 -,C32,1991
ORL-BWD LD50:23700 UG/KG AECTCV 12,355,1983
TARGET ORGAN DATA
BRAIN AND COVERINGS (INCREASED INTRACRANIAL PRESSURE)
PERIPHERAL NERVE AND SENSATION (SPASTIC PARALYSIS WITH/WITHOUT SENSORY CH
SENSE ORGANS AND SPECIAL SENSES (MYDRIASIS)
BEHAVIORAL (GENERAL ANESTHETIC)
BEHAVIORAL (SOMNOLENCE)
BEHAVIORAL (CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD)
BEHAVIORAL (CHANGE IN MOTOR ACTIVITY)
BEHAVIORAL (COMA)
BEHAVIORAL (HEADACHE)
BEHAVIORAL (IRRITABILITY)
CARDIAC (ARRYTHMIAS)
CARDIAC (PULSE RATE DECREASED WITH FALL IN BP)
CARDIAC (CHANGE IN FORCE OF CONTRACTION)
CARDIAC (OTHER CHANGES)
VASCULAR (BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION)
LUNGS, THORAX OR RESPIRATION (ACUTE PULMONARY EDEMA)
LUNGS, THORAX OR RESPIRATION (DYSPNAE)
LUNGS, THORAX OR RESPIRATION (RESPIRATORY STIMULATION)
LUNGS, THORAX OR RESPIRATION (OTHER CHANGES)
GASTROINTESTINAL (HYPERMOTILITY, DIARRHEA)
KIDNEY, URETER, BLADDER (OTHER CHANGES)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
CONTACT A LICENSED PROFESSIONAL WASTE DISPOSAL SERVICE TO DISPOSE OF
THIS MATERIAL.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
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PRODUCT #: 199931 NAME: SODIUM AZIDE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Thursday, March 20, 1903 3:08PM
CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
EC INDEX NO: 011-004-00-7
VERY TOXIC
R 28
VERY TOXIC IF SWALLOWED.
R 32
CONTACT WITH ACIDS LIBERATES VERY TOXIC GAS.
S 28
AFTER CONTACT WITH SKIN, WASH IMMEDIATELY WITH PLENTY OF WATER.
S 45
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
ACGIH TLV-NOT CLASSIFIABLE AS A HUMAN CARCINOGEN DTLVS* TLV/BEI,1996
ACGIH TLV-CL 0.29 MG/M3 DTLVS* TLV/BEI,1996
OEL-AUSTRALIA:TWA 0.1 PPM (0.3 MG/M3) JAN 1993
OEL-BELGIUM:STEL 0.11 PPM (0.3 MG/M3) JAN 1993
OEL-DENMARK:TWA 0.3 MG/M3 JAN 1993
OEL-FINLAND:TWA 0.1 PPM (0.3 MG/M3);STEL 0.3 PPM (0.9 MG/M3) JAN 1993
OEL-FRANCE:STEL 0.1 PPM (0.3 MG/M3) JAN 1993
OEL-GERMANY:TWA 0.07 PPM (0.2 MG/M3) JAN 1993
OEL-THE NETHERLANDS:TWA 0.1 PPM (0.3 MG/M3) JAN 1993
OEL-SWITZERLAND:TWA 0.07 PPM (0.2 MG/M3) JAN 1993
OEL-UNITED KINGDOM:TWA 0.1 PPM (0.3 MG/M3);STEL JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA CHECK ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV
NIOSH REL TO SODIUM AZIDE, AS HN3-AIR:CL 0.1 PPM (SK)
NIOSH* DHHS #92-100,1992
NOHS 1974: HZD 68820; NIS 13; TNF 877; NOS 10; TNE 5953
NOES 1983: HZD 68820; NIS 19; TNF 3640; NOS 27; TNE 54959; TFE 38370
EPA GENETOX PROGRAM 1988, POSITIVE: L5178Y CELLS IN VITRO-TK TEST
EPA GENETOX PROGRAM 1988, POSITIVE: D MELANOGASTER SEX-LINKED LETHAL
EPA GENETOX PROGRAM 1988, POSITIVE: S CEREVISIAE GENE CONVERSION
EPA GENETOX PROGRAM 1988, POSITIVE: S CEREVISIAE-FORWARD MUTATION; S
CEREVISIAE-REVERSION
EPA GENETOX PROGRAM 1988, NEGATIVE: IN VITRO CYTOGENETICS-HUMAN
LYMPHOCYTE
EPA GENETOX PROGRAM 1988, NEGATIVE: SPERM MORPHOLOGY-MOUSE; IN VITRO
UDS-HUMAN FIBROBLAST
EPA GENETOX PROGRAM 1988, NEGATIVE: TRP REVERSION
EPA GENETOX PROGRAM 1988, INCONCLUSIVE: CARCINOGENICITY-MOUSE/RAT; TRP
REVERSION
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
EPA TSCA SECTION 8(D) UNPUBLISHED HEALTH/SAFETY STUDIES
ON EPA IRIS DATABASE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, APRIL 1997
NIOSH CURRENT INTELLIGENCE BULLETIN 13, 1976
NTP CARCINOGENESIS STUDIES (GAVAGE); NO EVIDENCE: RAT
NTPTR* NTP-TR-389,91
U.S. INFORMATION
THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS.
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
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PRODUCT #: 199931 NAME: SODIUM AZIDE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Thursday, March 20, 1903 3:08PM
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1997 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC.,
FLUKA CHEMIE AG
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
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