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MSDS Material Safety Data Sheet
CAS

63-74-1

File Name: palomar_edu---sulfanilamide.asp
                        PRODUCT #: S9251        NAME: SULFANILAMIDE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Tuesday, March 18, 1903 2:08PM

Sigma Chemical Co. Aldrich Chemical Co., Inc. Fluka Chemical Corp.
P.O. Box 14508 1001 West St. Paul 1001 West St. Paul
St. Louis, MO 63178 Milwaukee, WI 53233 Milwaukee, WI 53233
Phone: 314-771-5765 Phone: 414-273-3850 Phone: 414-273-3850




SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
CATALOG #: S9251
NAME: SULFANILAMIDE
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 63-74-1
MF: C6H8N2O2S
EC NO: 200-563-4
SYNONYMS
ALBEXAN * ALBOSAL * AMBESIDE * P-AMINOBENZENESULFAMIDE * P-
AMINOBENZENESULFONAMIDE * 4-AMINOBENZENESULFONAMIDE * P-
AMINOPHENYLSULFONAMIDE * 4-AMINOPHENYLSULFONAMIDE * P-
ANILINESULFONAMIDE * ANILINE-P-SULFONIC AMIDE * ANTISTREPT *
ASTREPTINE * ASTROCID * BACTERAMID * BACTESID * BENZENESULFONAMIDE, P-
AMINO- * COLLOMIDE * COLSULANYDE * COPTICIDE * DESEPTYL * DIPRON *
ERGASEPTINE * ERYSIPAN * ESTREPTOCIDA * F 1162 * 1162 F * FOURNEAU
1162 * GERISON * GOMBARDOL * LUSIL * LYSOCOCCINE * NEOCOCCYL *
ORGASEPTINE * PABS * PRONTALBIN * PRONTOSIL ALBUM * PRONTOSIL I *
PRONTOSIL WHITE * PRONTYLIN * PRONZIN ALBUM * PROSEPTAL * PROSEPTINE *
PROSEPTOL * PYSOCOCCINE * RUBIAZOL A * SANAMID * SEPTAMIDE ALBUM *
SEPTANILAM * SEPTINAL * SEPTOLIX * SEPTOPLEX * SEPTOPLIX * STOPTON
ALBUM * STRAMID * STREPAMIDE * STREPSAN * STREPTAGOL * STREPTAMID *
STREPTASOL * STREPTOCID ALBUM * STREPTOCIDE WHITE * STREPTOCLASE *
STREPTOCOM * STREPTOL * P-SULFAMIDOANILINE * STREPTON * STREPTOSIL *
STREPTOZOL * STREPTOZONE * STREPTROCIDE * SULFAMIDYL * SULFAMINE *
SULFANA * SULFANALONE * SULFANIL * SULFOCIDIN * SULFOCIDINE *
SULFONAMIDE * SULFONAMIDE P * SULPHANILAMIDE * THERAPOL * WHITE
STREPTOCIDE *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
HARMFUL
HARMFUL BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT.
IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.
POSSIBLE RISK OF IRREVERSIBLE EFFECTS.
POSSIBLE MUTAGEN.
PHOTOSENSITIZER.
TARGET ORGAN(S):
KIDNEYS
DO NOT BREATHE DUST.
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
WEAR SUITABLE PROTECTIVE CLOTHING.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.

Page 1
PRODUCT #: S9251 NAME: SULFANILAMIDE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Tuesday, March 18, 1903 2:08PM

CALL A PHYSICIAN.
WASH CONTAMINATED CLOTHING BEFORE REUSE.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
WATER SPRAY.
CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
EVACUATE AREA.
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.
AVOID RAISING DUST.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT
GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.
USE ONLY IN A CHEMICAL FUME HOOD.
SAFETY SHOWER AND EYE BATH.
DO NOT BREATHE DUST.
DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
HARMFUL SOLID.
SENSITIZER.
IRRITANT.
POSSIBLE MUTAGEN.
KEEP TIGHTLY CLOSED.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
WHITE CRYSTALLINE POWDER
PHYSICAL PROPERTIES
MELTING POINT: 164 C TO 166 C
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
INCOMPATIBILITIES
STRONG OXIDIZING AGENTS
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
TOXIC FUMES OF:
CARBON MONOXIDE, CARBON DIOXIDE
NITROGEN OXIDES
SULFUR OXIDES
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN.
MAY CAUSE ALLERGIC RESPIRATORY AND SKIN REACTIONS.
MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER
RESPIRATORY TRACT.
CAUSES EYE AND SKIN IRRITATION.
PHOTOSENSITIZER.
MAY CAUSE NERVOUS SYSTEM DISTURBANCES.

Page 2
PRODUCT #: S9251 NAME: SULFANILAMIDE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Tuesday, March 18, 1903 2:08PM

EXPOSURE MAY CAUSE:
BLOOD EFFECTS
GASTROINTESTINAL DISTURBANCES
CHRONIC EFFECTS
LABORATORY EXPERIMENTS HAVE SHOWN MUTAGENIC EFFECTS.
TARGET ORGAN(S):
KIDNEYS
TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND
TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
RTECS #: WO8400000
SULFANILAMIDE
TOXICITY DATA
ORL-RAT LD50:3900 MG/KG 85JCAE -,1072,1986
IVN-RAT LD50:1400 MG/KG AEPPAE 211,367,1950
ORL-MUS LD50:3 GM/KG NYKZAU 48,336,1952
IPR-MUS LD50:5 MG/KG ABANAE
5,886,1957/1958
SCU-MUS LD50:2900 MG/KG ARZNAD 5,213,1955
IVN-MUS LD50:500 MG/KG ABANAE
5,972,1957/1958
ORL-DOG LD50:2 GM/KG PCOC** -,1079,1966
ORL-RBT LD50:1300 MG/KG GISAAA 31(3),11,1966
ORL-GPG LD50:3130 MG/KG JPETAB 82,86,1944
TARGET ORGAN DATA
SPECIFIC DEVELOPMENTAL ABNORMALITIES (BLOOD AND LYMPHATIC SYSTEMS)
EFFECTS ON NEWBORN (LIVE BIRTH INDEX)
EFFECTS ON NEWBORN (VIABILITY INDEX)
EFFECTS ON NEWBORN (WEANING OR LACTATION INDEX)
EFFECTS ON NEWBORN (GROWTH STATISTICS)
TUMORIGENIC (CARCINOGENIC BY RTECS CRITERIA)
TUMORIGENIC (TUMORS AT SITE OF APPLICATION)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A
CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
HARMFUL
R 20/21/22
HARMFUL BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
R 42/43
MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT.
R 36/37/38
IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.
R 40
POSSIBLE RISK OF IRREVERSIBLE EFFECTS.
S 22
DO NOT BREATHE DUST.
S 26
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF

Page 3
PRODUCT #: S9251 NAME: SULFANILAMIDE
MATERIAL SAFETY DATA SHEET, Valid 11/97 - 1/98
Printed Tuesday, March 18, 1903 2:08PM

WATER AND SEEK MEDICAL ADVICE.
S 36
WEAR SUITABLE PROTECTIVE CLOTHING.
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
NOHS 1974: HZD 84382; NIS 3; TNF 149; NOS 9; TNE 3565
NOES 1983: HZD 84382; NIS 6; TNF 654; NOS 11; TNE 6529; TFE 3131
EPA GENETOX PROGRAM 1988, POSITIVE: ASPERGILLUS-RECOMBINATION
EPA GENETOX PROGRAM 1988, NEGATIVE: ASPERGILLUS-ANEUPLOIDY; N
CRASSA-ANEUPLOIDY
EPA GENETOX PROGRAM 1988, INCONCLUSIVE: CARCINOGENICITY-MOUSE/RAT
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1997 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC.,
FLUKA CHEMIE AG
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY




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