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Biomolecules for research MATERIAL SAFETY DATA SHEET
Section 1 : Substance Identification
BIOMOL CV-Cathepsin K Detection Kit
Name:
Catalog Number: AK-126
Company Identification: BIOMOL International L.P.
5120 Butler Pike
Plymouth Meeting PA 19462-1202 USA
(610) 941-0430 (9am-5pm ET)
Section 2 : Components
Vial # Name: Contents: Quantity
KI-247 CR-(LR)2 Reagent Solid 1 vial
*See Attached MSDS for this reagent
KI-223 Acridine Orange 1 mM 0.5 ml
*See attached MSDS for this reagent
KI-189 Hoechst 33342 Stain 200碌g/ml 1 ml
*See attached MSDS for this reagent
AK-118 Instruction Booklet 1 booklet
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Biomolecules for research MATERIAL SAFETY DATA SHEET
Section 1 : Substance Identification
CR-(LR)2 Reagent
Name:
Component Number: KI-222
Z(Leu-Arg)2CR
Chemical Name:
Chemical Class: Peptide derivative
Company Identification: BIOMOL International L.P.
5120 Butler Pike
Plymouth Meeting PA 19462-1202 USA
(610) 941-0430 (9am-5pm ET)
Section 2 : Health Hazard Data
Acute Health Effects: May be harmful if ingested, inhaled, or absorbed through the skin. May cause
irritation . To the best of our knowledge, the toxicological properties of this compound have not
been fully investigated. Exercise appropriate precautions to prevent opportunities for inhalation,
and to prevent direct contact with skin and eyes. All uncharacterized chemicals should be treated
as suspected toxins.
Chronic Health Effects: unknown
Section 3 : First Aid Measures
Eye Contact: Check for and remove contact lenses. Flush eyes with running water for at least 15
minutes separating eyelids. Seek medical attention immediately.
Skin Contact: Wash with soap and water for 15 minutes. Remove contaminated clothing and shoes.
Seek medical attention immediately.
Inhalation: Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops,
administer artificial respiration. Seek medical attention immediately. Provide chemical label
and MSDS if possible.
Ingestion: Remove dentures and clear mouth. If person is conscious, rinse mouth with water. Call
physician or poison control immediately. Provide chemical label and MSDS information if
possible.
Section 4 : Fire and Explosion Data
Flammability: Not Available
Flash Point: Not Available
Combustion Products: Not Available
Extinguishing Media: Carbon Dioxide, Dry chemical powder, polymer foam, water spray
Special Firefighting Procedures: Use self-contained breathing apparatus and protective clothing to
prevent contact with skin and eyes.
Unusual Fire/Explosion Hazards: None known
Section 5 : Spill or Leak Procedures
Cleanup Procedures: Wearing appropriate protective gear as outlined under 鈥淧rotective equipment鈥?
wipe up spill and place in sealed container and hold for disposal. Avoid raising dust. Ventilate
the area and wash spill site after material has been removed.
Waste Disposal Method: Observe all Federal, State and Local regulations concerning the disposal of
this product.
Section 6 : Storage and Handling Precautions
Protective Equipment: For spill clean up, wear suitable protective clothing, chemical resistant rubber
gloves, rubber boots, and chemical safety goggles.
Storage and Handling: This product should be stored at 0-4掳C. It should be kept in a tightly
closed container and protected from light. This product should be handled only by qualified
experienced professionals. Wash thoroughly after handling this material.
Section 7 : Physical Data
Appearance: Red-Orange solid Odor: Not Available
Molecular Weight: 1068 Taste: Not Available
Boiling Point: Not Available Melting Point: Not Available
Solubility: limited water solubility Vapor Density: Not Available
Specific Gravity: Not Available Vapor Pressure: Not Available
Volatility: Not Available
Section 8 : Stability and Reactivity Data
Stability: This material is stable as supplied for >1 year if stored as directed
Conditions to Avoid: Exposure to Light
Incompatibles: Strong Oxidizing Agents
Section 9 : Toxicity Data
RTECS#: Not Available
Section 10 : Ecological Data
Ecotoxicological Information: None Available
The above information is believed to be correct but does not purport to be complete and should be used only as a guide. The burden of
safe use of this material rests entirely with the user.
Emergency Contact:
BIOMOL International L.P.
5120 Butler Pike
Plymouth Meeting, PA 19462 USA
(610) 941-0430
Last Revised : 1/7/04
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Biomolecules for research MATERIAL SAFETY DATA SHEET
Section 1 : Substance Identification
Name: Acridine Orange
Component Number: KI-223
Chemical Name: 6-bis-Diethylaminoacridine
Synonyms: AO, echrysine, rhoduline orange, waxoline orange, basic orange 14, Cl 46005, sumitomo
acridine orange RK
Company Identification: BIOMOL International L.P.
5120 Butler Pike
Plymouth Meeting PA 19462-1202 USA
(610) 941-0430 (9am-5pm ET)
Section 2 : Health Hazard Data
Acute Health Effects: May be harmful if ingested, inhaled, or absorbed through the skin. May cause
irritation of the eyes, skin, and respiratory system. Acridine Orange has been shown to be
mutagenic in laboratory tests. To the best of our knowledge, the toxicological properties of this
mixture have not been fully investigated. Exercise appropriate precautions to prevent opportunities
for inhalation, and to prevent direct contact with skin and eyes. Do not ingest.
Chronic Health Effects: Unknown
Section 3 : First Aid Measures
Eye Contact: Check for and remove contact lenses. Flush eyes with running water for at least 15
minutes separating eyelids. Seek medical attention immediately.
Skin Contact: Wash with soap and water for 15 minutes. Remove contaminated clothing and shoes.
Seek medical attention immediately.
Inhalation: Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops,
administer artificial respiration. Seek medical attention immediately. Provide chemical label
and MSDS if possible.
Ingestion: Remove dentures and clear mouth. If person is conscious, give large amounts of water, and
induce vomiting. If person is unconscious, await assistance. Call physician or poison control
immediately. Provide chemical label and MSDS information if possible.
Section 4 : Fire and Explosion Data
Flammability: Not Flammable
Flash Point: Not Available
Combustion Products: Carbon monoxide, Carbon dioxide, nitrogen oxides, Hydrogen chloride gas
Extinguishing Media: Carbon Dioxide, Dry chemical powder, polymer foam, water spray
Special Firefighting Procedures: Use self-contained breathing apparatus and protective clothing to
prevent contact with skin and eyes.
Unusual Fire/Explosion Hazards: None known
Section 5 : Spill or Leak Procedures
Cleanup Procedures: Wearing appropriate protective gear as outlined under 鈥淧rotective equipment鈥?
wipe up spill and place in sealed container and hold for disposal. Dispose of material in
compliance with all federal state and local regulations. Ventilate area and wash spill site after
material has been removed.
Waste Disposal Method: Observe all Federal, State and Local regulations concerning the disposal of
this product.
Section 6 : Storage and Handling Precautions
Protective Equipment: For spill clean up, wear suitable protective clothing, chemical resistant rubber
gloves, rubber boots, and chemical safety goggles. Self contained breathing apparatus or
NIOSH/MSHA approved respirator is recommended.
Storage and Handling: This product should be stored at 0-4掳C. It should be kept in a tightly
closed container, and protected from light and moisture. This product should be handled only by
qualified experienced professionals. Wash thoroughly after handling this material.
Section 7 : Physical Data
Appearance: Red Orange Aqueous Solution Odor: Not available
Molecular Weight: Not Available Taste: Not Available
Boiling Point: Not Available Melting Point: Not Available
Solubility: Water Vapor Density: Not Available
Specific Gravity: Not Available Vapor Pressure: Not Available
Volatility: Not Available pH: 3.8 -4.2
Section 8 : Stability and Reactivity Data
Stability: This material is stable as supplied for 1 year if stored as directed
Conditions to Avoid: Exposure to light and moisture
Incompatibles: Not Available
Section 9 : Toxicity Data
RTECS#: Not Available
Section 10 : Ecological Data
Ecotoxicological Information: None Available
The above information is believed to be correct but does not purport to be complete and should be used only as a guide. The burden of
safe use of this material rests entirely with the user.
Emergency Contact:
BIOMOL International L.P.
5120 Butler Pike
Plymouth Meeting, PA 19462 USA
(610) 941-0430
Last Revised : 1/7/04
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Biomolecules for research MATERIAL SAFETY DATA SHEET
Section 1 : Substance Identification
Hoechst 33342 Stain
Name:
Component Number: KI-189
Company Identification: BIOMOL International L.P.
5120 Butler Pike
Plymouth Meeting PA 19462-1202 USA
(610) 941-0430 (9am-5pm ET)
Section 2 : Health Hazard Data
Acute Health Effects: May be harmful if ingested, inhaled, or absorbed through the skin. May cause
irritation of the eyes, skin, and respiratory system. Hoechst 33342 stain has been shown to be
mutagenic in laboratory tests. The mutagenic properties have been demonstrated by DNA damage
to hamster lung cells and mouse fibroblast cells at 1 碌M and 5 碌M concentrations respectively.
This reagent also effected DNA inhibition in hamster lung cells at 1 碌M. To the best of our
knowledge, the toxicological properties of this mixture have not been fully investigated. Exercise
appropriate precautions to prevent opportunities for inhalation, and to prevent direct contact with
skin and eyes. Do not ingest. This product should be treated as a possible carcinogen.
Chronic Health Effects: Mutagenic in laboratory testing, possible carcinogen.
Section 3 : First Aid Measures
Eye Contact: Check for and remove contact lenses. Flush eyes with running water for at least 15
minutes separating eyelids. Seek medical attention immediately.
Skin Contact: Wash with soap and water for 15 minutes. Remove contaminated clothing and lauder
immediately. Throw away contaminated shoes.
Seek medical attention.
Inhalation: Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops,
administer artificial respiration. Seek medical attention immediately. Provide chemical label
and MSDS if possible.
Ingestion: Remove dentures and clear mouth. If person is conscious, give large amounts of water, milk,
or activated charcoal. If person is unconscious, await assistance. Call physician or poison
control immediately. Provide chemical label and MSDS information if possible.
Section 4 : Fire and Explosion Data
Flammability: Not Available
Flash Point: Not Available
Combustion Products: Not Available
Extinguishing Media: Carbon Dioxide, Dry chemical powder, 鈥渁lcohol鈥? foam
Special Firefighting Procedures: Use self-contained breathing apparatus and protective clothing to
prevent contact with skin and eyes.
Unusual Fire/Explosion Hazards: None Known
Section 5 : Spill or Leak Procedures
Cleanup Procedures: Wearing appropriate protective gear as outlined under 鈥淧rotective equipment鈥?
wipe up spill and place in sealed container and hold for disposal. Ventilate the area and wash spill
site after material has been removed. Eliminate ignition sources from the spill area.
Waste Disposal Method: Observe all Federal, State and Local regulations concerning the disposal of
this product.
Section 6 : Storage and Handling Precautions
Protective Equipment: Use only in a chemical fume hood, or with equivalent ventilation conditions.
For spill clean up, wear suitable protective clothing, chemical resistant rubber
gloves, rubber boots, and chemical safety goggles. Self contained breathing apparatus or
NIOSH/MSHA approved respirator is recommended.
Storage and Handling: This product should be stored at 0-4掳C. It should be kept in a tightly
closed container and protected from light. This product should be handled only by qualified
experienced professionals. Wash thoroughly after handling this material.
Section 7 : Physical Data
Appearance: Light Green Liquid (supplied in aqueous solution)
Odor: None
Molecular Weight: 616 Taste: Not Available
Boiling Point: 100掳C Melting Point: Not Available
Solubility: Not Available Vapor Density: Not Available
Specific Gravity: Not Available Vapor Pressure: Not Available
Volatility: Not Available pH: 3.9-4.4
Section 8 : Stability and Reactivity Data
Stability: This material is stable as supplied for 1 year if stored as directed
Conditions to Avoid: Protect from light
Incompatibles: None known
Section 9 : Toxicity Data
RTECS#: Not Available
Section 10 : Ecological Data
Ecotoxicological Information: None Available
The above information is believed to be correct but does not purport to be complete and should be used only as a guide. The burden of
safe use of this material rests entirely with the user.
Emergency Contact:
BIOMOL International L.P.
5120 Butler Pike
Plymouth Meeting, PA 19462 USA
(610) 941-0430
Last Revised : 1/7/04
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