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Biomolecules for research MATERIAL SAFETY DATA SHEET
Section 1 : Substance Identification
20S Proteasome Assay Kit for Drug Discovery
Name:
Catalog Number: AK-740
Company Identification: BIOMOL International L.P.
5120 Butler Pike
Plymouth Meeting PA 19462-1202 USA
(610) 941-0430 (9am-5pm ET)
Section 2 : Components
Vial # Name: Contents: Quantity
PW8720-9090 20S Proteasome Enzyme 1 mg/ml in 20 mM Tris, pH 7.2, 20碌g
(human erythrocyte) 50 mM NaCl, 5 mM MgCl2,
1 mM EDTA, and 1 mM sodium azide
*Blood product starting material has been tested and found to be negative for hepatitis B
surface antigen, hepatitis c virus, HIV type 1 antigens, and antibodies against HIV type 1
and 2
P802-9090 Suc-LLVY-AMC 0.375mM in Assay Buffer 1ml
(substrate)
KI-122 7-Amino-4-methylcoumarin 8碌M in Assay Buffer 1ml
(Calibration standard)
PI127-9090 Epoxomicin Solid 20 碌g
(Inhibitor)
KI-120 20S Assay Buffer 25mM HEPES, pH 7.5, 0.5mM 20ml
EDTA, 0.05% NP-40, 0.03% SDS.
AK-740 Instruction Booklet 1
KI-101 96-Well Plate 陆 Volume 96-well plate 1 plate
Section 3 : Health Hazards
Please be advised that the physical, chemical and toxicological properties of many of these components
have not yet been fully investigated. It is therefore advised that all laboratory personnel handling this
product follow standard laboratory safety procedures. It is recommended that personnel wear safety
goggles, gloves, and protective clothing at all times, and avoid direct contact with the reagents supplied in
this kit.
Section 4 : First Aid
Eye Contact: Check for and remove contact lenses. Flush eyes with running water for at least 15
minutes separating eyelids. Seek medical attention immediately
Skin Contact: Wash with soap and water for 15 minutes. Remove contaminated clothing and shoes.
If irritation or discomfort develops, seek medical attention.
Inhalation: Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops,
administer artificial respiration. Seek medical attention if patient feels unwell or develops any
respiratory symptoms. Provide chemical label and MSDS if possible.
Ingestion: Remove dentures and clear mouth. If person is conscious, rinse mouth with water. Call
physician or poison control immediately. Provide chemical label and MSDS information if
possible.
Section 5 : Fire / Flammability Information
None of the components of this kit pose a significant risk in case of fire. Fire fighting media should be
selected to suit other materials involved in the fire. It is recommended that firefighters wear protective gear
and self contained breathing apparatus to limit exposure.
Section 6 : Spill or Leak Procedures.
Cleanup Procedures: Wearing appropriate protective gear as outlined under 鈥淧rotective equipment鈥?
wipe up spill, place in sealed container and hold for appropriate disposal. Wash spill site with soap
and water.
Waste Disposal Method: Dilute waste solutions and reagents with water and dispose of in accordance
with federal, state, and local regulations.
Section 7 : Storage and Handling Precautions
Protective Equipment: For spill clean up, wear suitable protective clothing, chemical resistant rubber
gloves, rubber boots, and chemical safety goggles.
Storage and Handling: The components of this kit should be stored 鈥?70掳C with the exception of the
96-well plate, and the instruction booklet which can be stored at room temperature. All
components should be kept in tightly closed containers. This product should be handled only by
qualified experienced professionals. Wash thoroughly after handling the materials included in this
kit.
Section 8 : Stability and Reactivity Data
Stability: This material is stable if stored as directed
Conditions to Avoid: None known
Incompatibles: Not available
Section 10 : Ecological Data
Ecotoxicological Information: None Available
The above information is believed to be correct but does not purport to be complete and should be used only as a guide. The burden of
safe use of this material rests entirely with the user.
Emergency Contact:
BIOMOL International L.P.
5120 Butler Pike
Plymouth Meeting, PA 19462 USA
(610) 941-0430
Last Revised : 12/21/05
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