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Granubor 庐 Material Safety Data Sheet
(15%) DATE OF ISSUE May 2000
Supersedes November 1999 Version
1 Chemical product and company identification
Granubor
Product name:
MANUFACTURER:
Agricultural micronutrient
Product use:
U.S. Borax Inc.
Mixture (refer to Section 2)
Chemical formula:
Mixture (refer to Section 2)
Chemical name/synonyms: 26877 Tourney Road
Fertilizer Borate Granular Valencia, CA 91355-1847
(FBG)
Inorganic borates
Chemical family: EMERGENCY PHONE NUMBERS:
12179-04-3 and 12280-03-4
CAS registry number: 24 Hr. Medical Info. Service . . . (661) 284-5200
(Primary chemical constituents)
Chemtrec (Spills): . . . . . . . . . . . (800) 424-9300
(Refer to Section 15 for TSCA/DSL Chemical inventory listing)
2 Composition/information on ingredients
Standard and under the Canadian Controlled Products
This product contains greater than 85 percent (%) sodium
Regulations of the Hazardous Products Act (WHMIS), based on
tetraborate pentahydrate, Na2B4O7路5H2O, and greater than 10%
animal chronic toxicity studies. Refer to Sections 3 and 11 for
disodium octaborate tetrahydrate, Na2B8O13路4H2O, which are
details on hazards.
both hazardous under the OSHA Hazard Communication
3 Hazard identification
Skin contact: Granubor does not cause irritation to intact skin.
Emergency overview
Ingestion: Products containing Granubor are not intended for
Granubor is a white, odorless, powder substance that is not
ingestion. Granubor has a low acute toxicity. Small amounts (e.g.,
flammable, combustible, or explosive and has low acute oral
a teaspoon) swallowed accidentally are not likely to cause effects;
and dermal toxicity.
swallowing amounts larger than that may cause gastrointestinal
Potential ecological effects
symptoms.
Large amounts of Granubor can be harmful to plants and other
Cancer: Granubor is not a known carcinogen.
species. Therefore, the product should only be used as part of a
Reproductive/developmental: Animal ingestion studies in
balanced plant nutrition program preferably after soil and/or
several species, at high doses, indicate that borates cause
tissue analysis. Accidental releases to the environment should
reproductive and developmental effects. A human study of
be minimized.
occupational exposure to borate dust showed no adverse effect on
Potential health effects
reproduction.
Routes of exposure: Inhalation is the most significant route of
Target organs: No target organ has been identified in humans.
exposure in occupational and other settings. Dermal exposure
High dose animal ingestion studies indicate the testes are the
is not usually a concern because Granubor is poorly absorbed
target organs in male animals.
through intact skin.
Signs and symptoms of exposure: Symptoms of accidental
Inhalation: Occasional mild irritation effects to the nose and
over-exposure to Granubor might include nausea, vomiting and
throat may occur from inhalation of Granubor dust at levels
diarrhea, with delayed effects of skin redness and peeling. These
greater than 10 mg/m3.
symptoms have been associated with the accidental over-exposure
Eye contact: Granubor may cause mild eye irritation. Avoid
to the chemically related substance boric acid.
contact with eyes.
Refer to Section 11 for details on toxicological data.
4 First aid measures
Note to physicians: Observation only is required for adult
Inhalation: If symptoms such as nose or throat irritation are
ingestion in the range of 4-8 grams of Granubor. For ingestion of
observed, remove person to fresh air.
larger amounts, maintain adequate kidney function and force
Eye contact: Use eye wash fountain or fresh water to cleanse
fluids. Gastric lavage is recommended for symptomatic patients
the eye. If irritation persists for more than 30 minutes, seek
only. Hemodialysis should be reserved for massive acute
medical attention.
ingestion or patients with renal failure. Boron analyses of urine
Skin contact: No treatment necessary because non-irritating.
or blood are only useful for documenting exposure and should
Ingestion: Swallowing small quantities (one teaspoon) will
not be used to evaluate severity of poisoning or to guide
cause no harm to healthy adults. If larger amounts are
treatment1. Refer to Section 11 for details.
swallowed, give two glasses of water to drink and seek medical
attention.
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Granubor
5 Firefighting measures
Extinguishing media: Any fire extinguishing media may be
General hazard: None, because Granubor is not flammable,
used on nearby fires.
combustible or explosive. The product is itself a flame
Flammability classification (29 CFR 1910.1200): Non-
retardant.
flammable solid.
6 Accidental release measures
General: Granubor is a water-soluble white powder that may, at Spillage into water: Where possible, remove any intact
high concentrations, cause damage to trees or vegetation by containers from the water. Advise local water authority that
root absorption. (Refer to Ecological information, Section 12, none of the affected water should be used for irrigation or for
for specific information.) the abstraction of potable water until natural dilution returns the
boron value to its normal environmental background level.
Land spill: Vacuum, shovel or sweep up Granubor and place in
(Refer to Sections 12, 13 and 15 for additional information.)
containers for disposal in accordance with applicable local
Granubor is a non-hazardous waste when spilled or disposed of,
regulations. Avoid contamination of water bodies during
as defined in the Resource Conservation and Recovery Act
cleanup and disposal. Personal protective equipment is not
(RCRA) regulations (40 CFR 261). (Refer to Regulatory
needed to cleanup land spills.
information, Section 15, for additional references.)
7 Handling and storage
General: No special handling precautions are required, but dry, Ambient
Storage temperature:
indoor storage is recommended. To maintain package integrity
and to minimize caking of the product, bags should be handled Atmospheric
Storage pressure:
on a first-in, first-out basis. Good housekeeping procedures
should be followed to minimize dust generation and Moisture (caking)
Special sensitivity:
accumulation.
8 Exposure controls/personal protection
Engineering controls: Use local exhaust ventilation to keep Occupational exposure limits: The only specifically regulated
airborne concentrations of Granubor dust below permissible chemical component of Granubor is sodium tetraborate
exposure levels. pentahydrate.
Personal protection: Where airborne concentrations are
1 mg/m3
ACGIH/TLV:
expected to exceed exposure limits, NIOSH/MSHA certified
5 mg/m3
Cal OSHA/PEL:
respirators should be used. Eye goggles and gloves are not
10 mg/m3
OSHA/PEL (total dust):
required for normal industrial exposures, but may be warranted
if environment is excessively dusty.
9 Physical and chemical properties
White, odorless, crystalline solid 3.6% @ 20掳C
Appearance: Solubility in water:
1.75 >200掳C (392掳F) (heated in closed space)
Specific gravity: Melting point:
Negligible @ 20掳C 9.15 (3.0% solution)
Vapor pressure: pH @ 20掳C:
10 Stability and reactivity
General: Granubor is a stable product, but when heated, it Incompatible materials and conditions to avoid: Reaction
loses water, eventually forming anhydrous borates and sodium with strong reducing agents, such as metal hydrides or alkali
sulfate. metals, will generate hydrogen gas, which could create an
explosive hazard.
Hazardous decomposition: None.
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11 Toxicological information
Other
Acute toxicity
Reproductive/developmental toxicity: Animal feeding studies
Ingestion: Low acute oral toxicity; LD50 in rats is greater than
in rat, mouse and dog, at high doses, have demonstrated effects
2,000 mg/kg of body weight.
on fertility and testes2. Studies with the chemically related boric
Skin/dermal: No experimental data; low acute dermal toxicity;
acid in the rat, mouse and rabbit, at high doses, demonstrate
LD50 in rabbits is expected to be greater than 2,000 mg/kg of
developmental effects on the fetus, including fetal weight loss and
body weight. Granubor is poorly absorbed through intact skin.
minor skeletal variations3, 4. The doses administered were many
Inhalation: No experimental data. Other borates indicate low
times in excess of those to which humans would normally be
acute inhalation toxicity. Many years of occupational exposure
exposed5.
to boric acid and other borates indicate no increase in
Carcinogenicity/mutagenicity: No evidence of carcinogenicity
pulmonary disease.
in mice6. No mutagenic activity was observed for boric acid in a
Skin irritation: No experimental test data. Similar sodium
battery of short-term mutagenicity assays.
borate substances are non-irritants.
Human data: Human epidemiological studies show no increase
Eye irritation: Draize test in rabbits produced eye irritation
in pulmonary disease in occupational populations with chronic
effects. Many years of occupational exposure to Granubor
exposures to boric acid dust and sodium borate dust. A recent
indicates no adverse effects on human eye. Granubor is
epidemiology study under the conditions of normal occupational
considered to be a mild eye irritant.
exposure to borate dusts indicated no effect on fertility7.
Sensitization: No experimental test data. However, other
borates are not skin sensitizers.
12 Ecological information
Ecotoxicity data Fish toxicity:
Seawater9:
General: Boron (B) is the element in Granubor which is used
Dab, Limanda limanda
by convention to report borate product ecological effects. It
96-hr LC50 = 74 mg B/L鈥?
occurs naturally in seawater at an average concentration of 5 mg
10:
Freshwater
B/L and generally occurs in freshwater at concentrations up to 1
Rainbow trout, S. gairdneri (embryo-larval stage)
mg B/L. In dilute aqueous solutions the predominant boron
24-day LC50 = 88 mg B/L鈥?
species present is undissociated boric acid.
32-day LC50 = 54 mg B/L鈥?
Phytotoxicity: Boron is an essential micronutrient for healthy
Goldfish, Carassius auratus (embryo-larval stage)
growth of plants; however, it can be harmful to boron sensitive
7-day LC50 = 65 mg B/L鈥?
plants in high quantities. Care should be taken to minimize the
3-day LC50 = 71 mg B/L鈥?
amount of Granubor accidentally released to the environment.
Granubor should only be used as part of a balanced plant
Environmental fate data
nutrition program preferably after soil and/or tissue analysis.
Persistence/degradation: Boron is naturally occurring and
Algal toxicity:
ubiquitous in the environment. Granubor decomposes in the
Green algae, Scenedesmus subspicatus
environment to natural borate.
96-hr EC10 = 24 mg B/L鈥?
Octanol/water partition coefficient: No value. In aqueous
Invertebrate toxicity8:
solution the chemical constituents of Granubor are converted
Daphnids, Daphnia magna Straus
substantially into undissociated boric acid.
24-hr EC50 = 242 mg B/L鈥?
Soil mobility: Granubor is soluble in water and is leachable
鈥?
Test substance: sodium tetraborate
through normal soil.
13 Disposal considerations
Disposal guidance: Small quantities of Granubor can usually RCRA (40 CFR 261): Granubor is not listed under any sections
be disposed of at landfill sites. No special disposal treatment is of the Federal Resource Conservation and Recovery Act
required, but local authorities should be consulted about any (RCRA).
specific local requirements. Tonnage quantities of product NPRI (Canada): Granubor is not listed on the Canadian
should, if possible, be used for an appropriate application. National Pollutant Release Inventory.
Refer to Section 15 for additional regulatory information.
14 Transport information
DOT hazardous classification: The chemical constituents of TDG Canadian transportation: The chemical constituents of
Granubor are not regulated by the U.S. Department of Granubor are not regulated under Transportation of Dangerous
Transportation (DOT) and are therefore not considered a Goods (TDG).
hazardous material/substance. International transportation: The chemical constituents of
Granubor do not have UN Numbers, and are not regulated
under international rail, road, water or air transport regulations.
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15 Regulatory information
Safe Drinking Water Act (SDWA): The chemical constituents
OSHA/Cal OSHA: This MSDS document meets the
of Granubor are not regulated under the SDWA, 42 USC 300g-1,
requirements of both OSHA (29 CFR 1910.1200) and Cal OSHA
40 CFR 141 et seq. Consult state and local regulations for
(Title 8 CCR 5194 (g)) hazard communication standards. Refer
possible water quality advisories regarding boron compounds.
to Section 8 for regulatory exposure limits.
Clean Water Act (CWA) (Federal Water Pollution Control
WHMIS classification: Granubor is classified as Class D-
Act): 33 USC 1251 et seq.
Division 2A under Canadian WHMIS guidelines.
a) The chemical constituents of Granubor are not covered
Chemical inventory listing: The primary chemical constituents
by any water quality criteria of Section 304 of the CWA,
of Granubor, sodium tetraborate pentahydrate and disodium
33 USC 1314.
octaborate tetrahydrate, appear on several chemical inventory
b) They are not on the Section 307 List of Priority
lists (including the EPA TSCA inventory, Canadian DSL,
Pollutants, 33 USC 1317, 40 CFR 129.
European EINECS, Japanese MITI, Australian and Korean lists)
c) They are not on the Section 311 List of Hazardous
sometimes under the CAS No. representing the anhydrous form
Substances, 33 USC 1321, 40 CFR 116.
of these inorganic salts.
Canadian drinking water guideline: An 鈥淚nterim Maximum
Na2B4O7路5H2O / Na2B8O13路4H2O
Chemical Component
Acceptable Concentration鈥? (IMAC) for boron is currently set at
U.S. EPA TSCA Inventor y 1330-43-4 / 12008-41-2
5 mg B/L.
1330-43-4 / 12008-41-2
Canadian DSL
IARC: The International Agency for Research on Cancer (IARC)
215-540-4 / 234-541-0
EINECS
(a unit of the World Health Organization) does not list or
1-760 / 9312-3213
South Korea
categorize the chemical constituents of Granubor as
(1)-69 n/a
Japanese MITI
carcinogens.
RCRA: The chemical constituents of Granubor are not listed as
NTP Biennial Report on Carcinogens: The chemical
a hazardous waste under any sections of the Resource
constituents of Granubor are not listed.
Conservation and Recovery Act (RCRA) or regulations (40 CFR
OSHA carcinogen: The chemical constituents of Granubor are
261 et seq).
not listed.
Superfund: CERCLA/SARA. The chemical constituents of
California Proposition 65: The chemical constituents of
Granubor are not listed under CERCLA or its 1986 amendments,
Granubor are not listed on the Proposition 65 list of carcinogens
SARA, including substances listed under Section 313 of SARA,
or reproductive toxicants.
Toxic Chemicals, 42 USC 11023, 40 CFR 372.65, Section 302 of
Clean Air Act (Montreal Protocol): Granubor was not
SARA, Extremely Hazardous Substances, 42 USC 11002, 40 CFR
manufactured with and does not contain any Class I or Class II
355, or the CERCLA Hazardous Substances list, 42 USC 9604,
ozone depleting substances.
40 CFR 302.
16 Other information
Product label text hazard information*:
1. Litovitz T L, Norman S A, Veltri J C, Annual Report of the American
鈥? Do not ingest.
Association of Poison Control Centers Data Collection System. Am.
鈥? Ingestion may cause reproductive harm or birth defects
J. Emerg. Med. 4: 427-458 (1986).
based on animal data.
2. Weir R J, Fisher R S, Toxicol. Appl. Pharmacol. 23: 351-364 (1972).
鈥? May cause eye irritation
3. Fail et al., Fund. Appl. Toxicol. 17: 225-239 (1991).
鈥? Avoid contamination of food or feed.
4. Price et al., J. Am. Coll. Toxicol. 14: (2), 173 (Abst. P-17) (1995). 鈥? Not for use in post harvest food, drugs, or pesticides.
鈥? Refer to MSDS.
5. Murray F J, Regul. Toxicol. Pharmacol. (Dec. 1995).
鈥? KEEP OUT OF REACH OF CHILDREN.
6. National Toxicology Program (NTP)鈥揟oxicology and carcinogenesis
*Except for Canadian product.
studies of boric acid in B6C3F1 mice, Tech. Report Ser. No. 324,
National Fire Protection Assoc. (NFPA) classification:
U.S. Dept. of Health and Human Services. NIH Publ. No. 88-2580
Health 0
(1987).
Flammability 0
7. Whorton et al., Occup. Environ. Med. 51: 761-767 (1994).
Reactivity 0
8. Sch枚berl et al., Tenside Surfactants Detergents 25: 99-107 (1988). Hazardous Materials Information Systems (HMIS):
Red: (Flammability) 0
9. Hugman S J, Mance G, Water Research Centre Report 616-M (1983).
Yellow: (Reactivity) 0
10. Butterwick L, de Oude N, Raymond K, Ecotoxicol. Environ. Safety
Blue: (Acute Health) 1*
17: 339-371 (1989).
*Chronic Effects
For general information on the toxicology of inorganic borates,
For further information contact:
see Patty鈥檚 Industrial Hygiene and Toxicology, 4th Ed. Vol. II,
(1994), Chap. 42, Boron; ECETOC Tech. Report No. 63 (1995). U.S. Borax Inc.
Occupational Health & Product Safety
(661) 287-6050
Technical & Sales Support
(847) 318-5400 or (800) 729-2672
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