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File Name: neogen_com---09063.asp
Natural E-AD
Injectable d-alpha-Tocopherol with
vitamins A and D3

Warning
Do not add water to solution. For animal use only.

Keep out of reach of children.

Dosage and Administration
Intramuscular or subcutaneous administration only. May
be repeated as needed. If dose is greater than 5 mL,
equally divide the dose and inject at two different sites.

Swine mL
Indications SOWS AND GILTS:
2 weeks pre-partum ............ 4-6
Natural E-AD injectable
2 weeks pre-breeding .......... 4-6
d-alpha tocopherol with
PIGS:
AD is a clear, sterile water
At birth ................................. 1-2
emulsi铿乤ble solution of
At weaning .......................... 2-3
vitamin A, vitamin D3, and
vitamin E. This product is
Cattle (Dairy and Beef) mL
intended for use as an
COWS AND HEIFERS:
aid in the prevention
2-3 weeks pre-partum ........ 8-10
and treatment of vitamin
At calving ............................ 8-10
E de铿乧iencies in cattle,
Yearlings ............................... 5-6
sheep and swine. This
CALVES:
product is intended as a
At birth ................................. 4-6
supplemental source of
vitamins A, D and E. At weaning .......................... 4-6
Yearlings ............................... 5-6
Each mL contains
Sheep mL
Vitamin E (as d-alpha-tocopherol,
EWES:
a natural source of vitamin E) ......................... 300 IUs
2-3 weeks pre-partum ......... 4-5
Vitamin A propionate ............................... 100,000 IUs At lambing ........................... 4-5
Vitamin D3.................................................... 10,000 IUs LAMBS:
At birth ................................. 2-3
Compounded with 2% benzyl alcohol (preservative)
At weaning .......................... 2-3
in a water emulsi铿乤ble base.
Finishing lambs .................... 3-4
Caution
Storage
Federal law restricts this drug to use by or on the
Store between 2-30掳C (36-86掳F) in a dark place.
order of a licensed veterinarian. Do not exceed
recommended dosage. Occasionally, reactions of an
Presentation
anaphylactic or allergic nature may occur. Should such
reactions occur, treat immediately with injection of
#09063 250 mL vial
epinephrine or antihistamines.
12/case
Administration of the product to well nourished
animals may cause hypervitaminosis D which may
result in hypercalcemia.




Neogen Corporation, 944 Nandino Blvd., Lexington, KY 40511 USA 鈥? 800/525-2022 鈥? Fax: 877/228-7229 鈥? www.neogen.com 鈥? e-mail: inform@neogen.com
Natural E-AD
Injectable d-alpha-Tocopherol with
vitamins A and D3

What is Natural E-AD?
Vitamin E is a fat soluble vitamin and is associated Vitamin A is essential to cell integrity and metabolic
with membranes in the tissues of animals. In tissues, functions including reproduction, proper growth and
the action of some enzymes and the auto-oxidation maintenance of surface epithelium, bone develop-
of unsaturated lipids results in the formation of ment, vision and mucosal secretions.
hydrogen peroxide and lipid peroxides. Peroxides are Vitamin D, although an essential vitamin to food
highly reactive and form free radicals that damage animals, vitamin D deficiency remains somewhat
proteins and other compounds. Vitamin E functions controversial. Animals exposed to sunlight or ultra-
to prevent the formation of the free radicals and, violet light produce their own natural vitamin D by
therefore, protects the tissues and membranes from the breakdown of certain fats in the skin.
undesirable damage. Vitamin E is essential to the
integrity and optimum function of the reproductive,
muscular, circulatory, nervous and immune systems.
Vitamin E鈥檚 function as a natural antioxidant is the
underlying factor.




Natural E-AD versus the competition

Features Natural E-AD Competitor
Source of vitamin A Propionate Palmitate

Level of vitamin A activity 2.5 million I.U. per gram 1.8 million I.U. per gram

Extended shelf life/dating Yes-24 months 12 months

Ethyl alcohol No Yes-20%

Injection site irritation None Yes

Intramuscular tissue damage None Yes

Highly syringeable in cold weather Yes No

Pharmaceutical grade natural vitamin E Yes Quality unknown

Refrigerate unused portion Not necessary Must refrigerate




Neogen Corporation, 944 Nandino Blvd., Lexington, KY 40511 USA 鈥? 800/525-2022 鈥? Fax: 877/228-7229 鈥? www.neogen.com 鈥? e-mail: inform@neogen.com
漏Neogen Corporation, 2006. Neogen is a registered trademark and NeogenVet is a trademark of Neogen Corp., Lansing, MI. L839-0406

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