**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 100-25-4 |p-Dinitrobenzene | 98 | 202-833-7 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T+ N
Risk Phrases: 26/27/28 33 50/53
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Very toxic by inhalation, in contact with skin and if swallowed.
Danger of cumulative effects. Very toxic to aquatic organisms, may
cause long-term adverse effects in the aquatic environment.
Potential Health Effects
Eye:
May cause eye irritation. May cause visual impairment. Contact
with the eye may cause yellow discoloration of the conjunctiva and
sclera.
Skin:
May be absorbed through the skin. Absorption into the body may cause
cyanosis (bluish discoloration of skin due to deficient oxygenation
of the blood). May cause yellow-brown discoloration of the hair and
exposed of workers has been reported.
Ingestion:
May be fatal if swallowed. May cause irritation of the digestive
tract. May cause liver damage. May cause methemoglobinemia, cyanosis
(bluish discoloration of skin due to deficient oxygenation of the
blood), convulsions, and death. May cause tissue anoxia,
characterized by weakness, headache, dizziness, confusion, cyanosis
(bluish skin due to deficient oxygenation of the blood), weak and
irregular heart beat, collapse, unconsciousness, convulsions, coma
and death. Methemoglobinemia is characterized by dizziness,
drowsiness, headache, shortness of breath, cyanosis (bluish
discoloration of skin due to deficient oxygenation of the blood),
rapid heart rate and chocolate-brown colored blood.
Inhalation:
Causes respiratory tract irritation. May cause effects similar to
those described for ingestion.
Chronic:
Chronic exposures of workers to dinitrobenzene have caused anemia;
liver injury has been reported in a few cases. Visual impairment has
occurred in the form of reduced visual acuity and central scotomas
(loss or depression of vision within the central visual field),
particularly for red and green colors. A yellow discoloration of the
conjunctiva and the sclera was a common observation in these
exposures (ACGIH Documentation of the TLV).
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid immediately. Flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes.
SPEEDY ACTION IS CRITICAL! Treat patient as for inhalation.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Get medical aid immediately. Treat patient
as for inhalation.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device
such as a bag and a mask.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Dusts at sufficient concentrations can form
explosive mixtures with air. During a fire, irritating and highly
toxic gases may be generated by thermal decomposition or combustion.
Use water spray to keep fire-exposed containers cool. Material is
shock sensitive and potentially explosive. Greatly increases the
burning rate of combustible materials. Containers may explode when
heated.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use flooding
quantities of water as spray. Cool containers with flooding
quantities of water until well after fire is out.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective
Equipment section. Avoid generating dusty conditions. Remove all
sources of ignition. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Minimize dust
generation and accumulation. Avoid contact with eyes, skin, and
clothing. Keep container tightly closed. Keep away from heat, sparks
and flame. Do not ingest or inhale. Avoid mechanical shock and
friction.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Keep container closed when not in use. Store in a tightly
closed container. Store in a cool, dry, well-ventilated area away
from incompatible substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne
concentrations below the permissible exposure limits.
Exposure Limits
CAS# 100-25-4:
United States OSHA: 1 mg/m3 TWA
Japan: 0.15 ppm OEL; 1 mg/m3 OEL
Malaysia: 0.15 ppm TWA; 1.0 mg/m3 TWA
Spain: 0.15 ppm VLA-ED; 1 mg/m3 VLA-ED
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Crystals
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Negligible
Viscosity: Not available.
Boiling Point: 299 deg C
Freezing/Melting Point: 173-175 deg C
Autoignition Temperature: Not available.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: 1.6300 g/cm3
Molecular Formula: C6H4N2O4
Molecular Weight: 168.11
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures. Substance is
sublimable, able to go directly from solid to vapor. o-Dinitrobenzene
may explode if subjected to shock, friction, or heating under
confinement.
Conditions to Avoid:
Dust generation.
Incompatibilities with Other Materials:
Metals, strong oxidizing agents, caustics (e.g. ammonia, ammonium
hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide).
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 100-25-4: CZ7525000
LD50/LC50:
Not available.
Oral LD50, rat: < 50 mg/kg (Eastman Kodak).
1970, in workers, apparently due to absorption through the skin.
(Eastman Kodak).
Carcinogenicity:
p-Dinitrobenzene -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: DINITROBENZENES
Hazard Class: 6.1
UN Number: 1597
Packing Group: II
IMO
Shipping Name: DINITROBENZENES, SOLID
Hazard Class: 6.1
UN Number: 1597
Packing Group: II
RID/ADR
Shipping Name: DINITROBENZENES
Hazard Class: 6.1
UN Number: 1597
Packing group: II
USA RQ: CAS# 100-25-4: 100 lb final RQ (Listed under Dinitrobenzene, mixed); 45.
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+ N
Risk Phrases:
R 26/27/28 Very toxic by inhalation, in contact with
skin and if swallowed.
R 33 Danger of cumulative effects.
R 50/53 Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 60 This material and its container must be
disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 100-25-4: 3
Canada
CAS# 100-25-4 is listed on Canada's DSL List.
CAS# 100-25-4 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 100-25-4 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 5/14/1998 Revision #3 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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