**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 101-68-8 |Methylenedi-p-phenyl diisocyanate | >97 | 202-966-0 |
|----------------|--------------------------------------|----------|-----------|
| 128-37-0 |2,6-Di-tert-butyl-p-cresol | .01 | 204-881-4 |
|----------------|--------------------------------------|----------|-----------|
| 5873-54-1 |Diphenylmethane-2,4'-diisocyanate | <2.5 | 227-534-9 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: XN
Risk Phrases: 36/37/38 42/43 20
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. May cause
sensitization by inhalation and skin contact. Harmful by inhalation.
Potential Health Effects
Eye:
Causes eye irritation. Lachrymator (substance which increases the
flow of tears).
Skin:
Causes skin irritation. May cause skin sensitization, an allergic
reaction, which becomes evident upon re-exposure to this material. A
single prolonged skin exposure is not likely to result in the
material being absorbed in harmful amounts. Isocyanates, in general,
can cause skin discoloration (staining) and hardening of the skin
after repeated exposures.
Ingestion:
May cause irritation of the digestive tract.
Inhalation:
May be fatal if inhaled. Causes respiratory tract irritation. May
cause asthmatic attacks due to allergic sensitization of the
respiratory tract. Impaired lung functions (decreased ventilatory
capacity) has been associated with overexposure to isocyanate.
Chronic:
Repeated or prolonged exposure may cause allergic reactions in
sensitive individuals. Tissue injury in the upper respiratory tract
and lungs has been observed in laboratory animals after repeated
excessive exposures to MDI/polymeric MDI aerosols.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with soap and plenty of
water. Remove contaminated clothing and shoes. Get medical aid if
symptoms occur. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
Containers can build up pressure if exposed to heat and/or fire. As
in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases may
be generated by thermal decomposition or combustion. Approach fire
from upwind to avoid hazardous vapors and toxic decomposition
products.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide. Water or water-based
foam, if used in very large quantities, may be effective for
fighting fires involving methylene bisphenyl isocyanate (MDI).
However, care must be taken since the reaction between water or
water-based foam and hot MDI can be vigorous.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation. Evacuate unnecessary personnel.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Avoid contact with eyes, skin, and clothing. Do
not breathe dust, vapor, mist, or gas. Keep container tightly
closed. Use only with adequate ventilation.
Storage:
Store in a cool, dry place. Keep container closed when not in use.
Keep refrigerated. (Store below 4C/39F.) Store under nitrogen.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other
engineering controls to control airborne levels below recommended
exposure limits. Facilities storing or utilizing this material should
be equipped with an eyewash facility and a safety shower.
Exposure Limits
CAS# 101-68-8:
United States OSHA: ; 0.02 ppm Ceiling; 0.2 mg/m3 Ceiling
Belgium - TWA: 0.005 ppm VLE; 0.052 mg/m3 VLE
France - VME: 0.01 ppm VME; 0.1 mg/m3 VME
France - VLE: 0.02 ppm VLE (5 min); 0.2 mg/m3 VLE (5 min)
Germany: 0.05 mg/m3 TWA
Japan: 0.05 mg/m3 OEL
Malaysia: 0.005 ppm TWA; 0.051 mg/m3 TWA
Netherlands: 0.02 ppm STEL; 0.21 mg/m3 STEL
Netherlands: 0.005 ppm MAC; 0.05 mg/m3 MAC
Russia: 0.5 mg/m3 TWA
Spain: 0.005 ppm VLA-ED; 0.052 mg/m3 VLA-ED
CAS# 128-37-0:
United Kingdom, WEL - TWA: 10 mg/m3 TWA
United Kingdom, WEL - STEL: 30 mg/m3 STEL
Belgium - TWA: 10 mg/m3 VLE
France - VME: 10 mg/m3 VME
Germany: 10 mg/m3 TWA (inhalable fraction)
Malaysia: 10 mg/m3 TWA
Netherlands: 10 mg/m3 MAC
CAS# 5873-54-1:
Personal Protective Equipment
Eyes:
Wear chemical splash goggles and face shield.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Flakes
Color: white to pale yellow
Odor: slightly musty
pH: Not available.
Vapor Pressure: 0.000005 mm Hg @ 25 deg C
Viscosity: Not available.
Boiling Point: 392 deg C
Freezing/Melting Point: 38-44 deg C
Autoignition Temperature: 240 deg C ( 464.00 deg F)
Flash Point: 196 deg C ( 384.80 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: 0.2%
Specific Gravity/Density: 1.19 @ 70C
Molecular Formula: C15H10N2O2
Molecular Weight: 250.26
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures. Polymerizes if
heated above 204C / 399F. MDI is readily dimerized and trimerized
by heat. Reacts vigorously with water above 50C (122F). MDI may
undergo uncontrolled exothermic polymerization upon contact with
incompatible materials, especially strong bases, such as
triethylamine and sodium hydroxide, trialkyl phosphines, potassium
acetate, & many metal compounds soluble in organic media.
Conditions to Avoid:
High temperatures, dust generation, moisture, At room temperature,
MDI reacts slowly with water forming carbon dioxide and inert
material comprised of non-toxic polyureas which could rupture closed
containers. 4,4'-Methylene dianiline is formed as an intermediate
product in this reaction..
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, strong bases, alcohols,
amines, organotin catalysts.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: May occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 101-68-8: NQ9350000
CAS# 128-37-0: GO7875000
CAS# 5873-54-1 unlisted.
LD50/LC50:
CAS# 101-68-8: Draize test, rabbit, eye: 100 mg Moderate; Draize
test, rabbit, skin: 500 mg/24H; Inhalation, rat: LC50 = 178 mg/m3;
Oral, mouse: LD50 = 2200 mg/kg; Oral, rat: LD50 = 9200 mg/kg.
CAS# 128-37-0: Draize test, rabbit, eye: 100 mg/24H Moderate; Draize
test, rabbit, skin: 500 mg/48H Moderate; Oral, mouse: LD50 = 650
mg/kg; Oral, mouse: LD50 = 1040 mg/kg; Oral, rabbit: LD50 = 2100
mg/kg; Oral, rat: LD50 = 890 mg/kg.
CAS# 5873-54-1.
Inhalation LC50 rat: 369-380 mg/m3/4H. (ACGIH documentation)
Carcinogenicity:
Methylenedi-p-phenyl diisocyanate -
Not listed by ACGIH, IARC, or NTP.
2,6-Di-tert-butyl-p-cresol -
Not listed by ACGIH, IARC, or NTP.
Diphenylmethane-2,4'-diisocyanate -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Daphnia: Daphnia: 0.35 mg/l; 24H; EC50Fish: Zebrafish: >100 mg/l;
96H; LC50
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
USA RQ: CAS# 101-68-8: 5000 lb final RQ; 2270 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20 Harmful by inhalation.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 42/43 May cause sensitization by inhalation and
skin contact.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 101-68-8: 1
CAS# 128-37-0: 1
CAS# 5873-54-1: No information available.
Canada
CAS# 101-68-8 is listed on Canada's DSL List.
CAS# 128-37-0 is listed on Canada's DSL List.
CAS# 5873-54-1 is listed on Canada's DSL List.
CAS# 101-68-8 is listed on Canada's Ingredient Disclosure List.
CAS# 128-37-0 is listed on Canada's Ingredient Disclosure List.
CAS# 5873-54-1 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 101-68-8 is listed on the TSCA inventory.
CAS# 128-37-0 is listed on the TSCA inventory.
CAS# 5873-54-1 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
MSDS Creation Date: 3/13/1998 Revision #4 Date: 8/04/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|