**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 101-80-4 |4,4'-Diaminodiphenyl ether | 98 | 202-977-0 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T
Risk Phrases: 22 45
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful if swallowed. May cause cancer.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May cause skin sensitization, an allergic
reaction, which becomes evident upon re-exposure to this material.
Ingestion:
May cause irritation of the digestive tract. May cause
methemoglobinemia, cyanosis (bluish discoloration of skin due to
deficient oxygenation of the blood), convulsions, and death.
Methemoglobinemia is characterized by dizziness, drowsiness,
headache, shortness of breath, cyanosis (bluish discoloration of
skin due to deficient oxygenation of the blood), rapid heart rate and
chocolate-brown colored blood. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. Methemoglobinemia is
characterized by dizziness, drowsiness, headache, shortness of
breath, cyanosis (bluish discoloration of skin due to deficient
oxygenation of the blood), rapid heart rate and chocolate-brown
blood. Inhalation of aniline causes anoxia due to the formation of
methemoglobin.
Chronic:
Prolonged exposure may cause anemia and methemoglobinemia,
characterized by dizziness, drowsiness, headache, breath shortness,
cyanosis (bluish skin due to deficient oxygenation of the blood),
rapid heart rate and chocolate-brown colored blood. Repeated exposure
may cause sensitization dermatitis. Effects may be delayed. Potential
cancer hazard.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and
drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid. Do NOT use mouth-to-mouth
resuscitation.
Notes to Physician:
For methemoglobinemia, administer oxygen alone or with Methylene
Blue depending on the methemoglobin concentration in the blood.
Antidote:
Methylene blue, alone or in combination with oxygen is indicated as
a treatment in nitrite induced methemoglobinemia.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Use water
spray to keep fire-exposed containers cool. May polymerize
explosively when involved in a fire. Contact with metals may evolve
flammable hydrogen gas. Containers may explode when heated.
Combustible material; may burn but does not ignite readily.
Extinguishing Media:
Do NOT get water inside containers. For small fires, use dry
chemical, carbon dioxide, or water spray. For large fires, use dry
chemical, carbon dioxide, alcohol-resistant foam, or water spray.
Cool containers with flooding quantities of water until well after
fire is out.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective
Equipment section. Sweep up, then place into a suitable container for
disposal. Avoid generating dusty conditions. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes,
skin, and clothing. Keep container tightly closed. Avoid ingestion
and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 101-80-4:
Russia: 5 mg/m3 TWA
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Powder
Color: almost white
Odor: none reported
pH: Not available.
Vapor Pressure: 0.06 hPa @ 20 C
Viscosity: Not available.
Boiling Point: 190 deg C
Freezing/Melting Point: 188-190 deg C
Autoignition Temperature: Not applicable.
Flash Point: > 218 deg C (> 424.40 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C12H12N2O
Molecular Weight: 200.24
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 101-80-4: BY7900000
LD50/LC50:
CAS# 101-80-4: Oral, mouse: LD50 = 685 mg/kg; Oral, rabbit: LD50 =
700 mg/kg; Oral, rat: LD50 = 725 mg/kg.
Carcinogenicity:
4,4'-Diaminodiphenyl ether -
California: carcinogen, initial date 1/1/88
NTP: Suspect carcinogen
IARC: Group 2B carcinogen
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Other
For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND
EXPOSURE DATA."
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 45 May cause cancer.
R 22 Harmful if swallowed.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 101-80-4: No information available.
Canada
CAS# 101-80-4 is listed on Canada's NDSL List.
CAS# 101-80-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 101-80-4 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 9/02/1997 Revision #8 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
3'-Aminoacetophenone, 97%
| 99-03-6 |
|
8-Azaguanine, 98%
| 134-58-7 |
|
N,N-Dimethyl-p-phenylenediamine oxalate, 99% (titr.)
| 62778-12-5 |
|
4-Ethoxy-2-Buten-1-ol, 98% (Mixt. Cis and Trans Isomers)
| 123093-78-7 |
|
Decanoyl Chloride, 98%
| 112-13-0 |
|
N,N'-Bis(3-Aminopropyl)-1,3-Propane- Diamine, 97% (Titr.)
| 4605-14-5 |
|
2,3-Bis-(Bromomethyl)Quinoxaline, 98%
| 3138-86-1 |
|
4-N-propylbiphenyl-4'-carboxylic acid, 98%
| 88038-94-2 |
|
4-Nitrobenzoyl chloride, 98%
| 122-04-3 |
|
N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine, 99% (titr.)
| 140-07-8 |
|
2-(4-Carboxyphenoxy)-2-Pivaloyl-2',4'-Dichloroacetanilide, 96% (HPLC)
| 58161-93-6 |
|
Ethyl 7-nitroindole-2-carboxylate, 95+%
| 6960-46-9 |
|
Cyclohexanecarboxylic Acid Chloride, 98% by Titration
| 2719-27-9 |
|
Gadolinium atomic absorption standard solution, 1 mg/ml Gd in 2% HNO3
| 7440-54-2 |
|
trans-1,2-Dichlorocyclohexane, 97%
| 822-86-6 |
|
Ethyl 4-fluorobenzoate ,99%
| 451-46-7 |
|
4-Aminophenyl ether, 98%
| 101-80-4 |
|
Dodecylthioacetonitrile, 92% (GC)
| 51956-42-4 |
|
Cyclopropyl bromide, 99%
| 4333-56-6 |
|
Hydrogenhexahydroxyplatinate (IV), ca. 64% Pt
| 51850-20-5 |
|
Trimethyl-1,5,9-Cyclododecatriene (Mixture of Isomers), 98%
| 27193-69-7 |
|
4,4'-Diamino-2,2'-biphenyldisulfonic acid (techn), 85% (titr.)
| 117-61-3 |
|
Valeramide
| 626-97-1 |
|
4-(Chloromethyl)-3,5-Dimethyl-Isoxazole 98%
| 19788-37-5 |
|
1,2,4-Trimethylbenzene, 98%
| 95-63-6 |
|
Sec-Butyl Disulfide, 98%
| 593-30-6 |
|
Platinum(ii) chloride, 73% pt
| 10025-65-7 |
|
8-Azahypoxanthine, 98%
| 2683-90-1 |
|
(2-Bromoethyl)-Trimethylammonium Bromide, 98%
| 2758-06-7 |
|
3',5'-Dihydroxyacetophenone, 97%
| 51863-60-6 |
|
4,5-Dimethoxy-2-Mercapto-Benzylamine Hydrochloride, 92%
| 21407-29-4 |
|
4-Amino-2-methylmercaptoquinazoline
| 63963-40-6 |
|
Z-1,3-Dichloropropene
| 542-75-6 |
|
4-Fluorosulfonyl-1-hydroxy-2-naphthoic acid, 99%
| 839-78-1 |
|
Tris(2-ethylhexyl)trimellitate, 98%
| 3319-31-1 |
|
4-Methoxyphenol, 99%
| 150-76-5 |
|
Rose bengal, high purity biological stain
| 632-69-9 |
|
Thionicotinamide, 99%
| 4621-66-3 |
|
Magnesium iodate tetrahydrate, 98%
| 0-00-1 |
|
Harmaline hydrochloride dihydrate
| 6027-98-1 |
|
Trans-Aconitic Acid, 98%
| 4023-65-8 |
|
3,4-Dichlorobenzophenone, 99%
| 6284-79-3 |
|
1,4-Dichloro-2,3-butanediol, mixture of DL- and meso, 99.0%
| 2419-73-0 |
|
Di-n-octadecyl phosphite, 95% c18, (gc)
| 19047-85-9 |
|
Aza-12-Crown-4, 99.5+%
| 41775-76-2 |
|
4-Isopropylaniline, 99%
| 99-88-7 |
|
sec-Butylbenzene, 99+%
| 135-98-8 |
|
Ethyl Carbanilate
| 101-99-5 |
|
2-Chloronicotinic Acid, 98%
| 2942-59-8 |
|
2-Bromoacetamide, 98%
| 683-57-8 |
|
|